The development of the vertebrate inner ear

Mechanisms of Development

Volumn 71, Issue 1-2, 1998, Pages 5-21

  Torres, Miguel ^a   Giráldez, Fernando ^b  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b Universidad de Valladolid y Consejo Superior de Investigaciones Científicas   (Spain)

Author keywords

Development; Inner ear

Indexed keywords

CELL PROLIFERATION; DEVELOPMENTAL GENETICS; ECTODERM; EMBRYO DEVELOPMENT; ENDODERM; GENE DISRUPTION; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; INNER EAR; INNERVATION; MESODERM; MULTIGENE FAMILY; NEURAL TUBE; NEUROECTODERM; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; REVIEW; SOUND DETECTION; VERTEBRATE;

MAMMALIA; RODENTIA; VERTEBRATA;

EID: 0032007713     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(97)00155-X     Document Type: Article

References (151)

1. Abbott B.D., Probst M.R. Developmental expression of two members of a new class of transcription factors. II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo. Dev. Dyn. 204:1995;144-155.
2. Abdelhak S., Kalatzis V., Heilig R., Compain S., Samson D., Vincent C., Weil D., Cruaud C., Sahly I., Leibovici M., Bitner-Glindzicz M., Francis M., Lacombe D., Vigneron J., Charachon R., Boven K., Bedbeder P., Van Regemorter N., Weissenbach J., Petit C.A. Human homologue of the Drosophila eyes absent gene underlies branchio-oto-renal (BOR) syndrome and identifies a novel gene family. Nat Genet. 15:1997;157-164.
3. Adler H.J., Raphael Y. New hair-cells arise from supporting cell conversion in the acoustically damaged chick ear. Neurosci. Lett. 205:1996;17-20.
4. Akimenko M.A., Ekker M., Wegner J., Lin W., Westerfield M. Combinatorial expression of the three zebrafish genes related to Distal-less: part of a homeobox gene code for the head. J. Neurosci. 14:1994;3475-3486.
5. Ammin Hossain W., Zhou X., Rutledge A., Baier C., Morest D.K. Basic fibroblast growth factor affects neuronal migration and differentiation in normotypic cell cultures from the cochleovestibular ganglion of the chick embryo. Exp. Neurol. 138:1996;121-143.
6. Anniko, M., 1983. Embryonic development of vestibular sense organs and their innervation. In: Romand, R. (Ed.), Development of Auditory and Vestibular Systems, Vol. 2. Elsevier, Amsterdam, pp. 375-423.
7. Avila M., Varela-Nieto I., Romero G., Mato J.M., Giraldez F., Van e Water T.R., Represa J. Brain-derived neurotrophic factor and neurotrophin-3 support the survival and neuritogenesis response of developing cochleovestibular ganglion neurons. Dev. Biol. 159:1993;266-275.
8. Barbacid, M., 1994. The Trk family of neurotrophin receptors. J. Neurobiol. 25, 1386-1403.
9. Bianchi L.M., Cohan C.S. Effects of the neurotrophins and CNTF on developing statoacoustic neurons: comparison with an otocyst-derived factor. Dev. Biol. 159:1993;353-365.
10. Biffo S., Offenhauser N., Carter B.D., Barde Y.A. Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development. Development. 121:1995;2461-2470.
11. Blitz I.L., Cho K.W. Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene orthodenticle. Development. 121:1995;993-1004.
12. Bradley D.J., Towle H.C., Young W.S. a and b thyroid hormone receptor (TR) gene expression during auditory neurogenesis: evidence for TR isoform-specific transcriptional regulation in vivo. Proc. Natl. Acad. Sci. USA. 91:1994;439-443.
13. Brand M., Heisenberg C.P., Jiang Y.J., Beuchle D., Lun K., Furutani-Seiki M., Granato M., Haffter P., Hammerschmidt M., Kane D., Kelsh R., Mullins M., Odenthal J., Nusslein-Volhard C. Mutations in zebrafish affecting the formation of the boundary between midbrain and hindbrain. Development. 123:1996;179-190.
14. Bulfone A., Kim H.J., Puelles L., Porteus M.H., Grippo J.F., Rubenstein J.L. The mouse Dlx-2 (Tes-1) gene is expressed in spatially restricted domains of the forebrain, face and limbs in midgestation mouse embryos. Mech. Dev. 40:1993;129-140.
15. Chao M.V. Neurotrophin receptors: a window into neuronal differentiation. Neuron. 9:1992;583-593.
16. Cheyette B.B.R., Green P.J., Martin K., Garren H., Hartestein V., Zipursky S.L. The Drosophila sine oculis locus encodes a homeodomain-containing protein required for the development of the entire visual system. Neuron. 12:1994;977-996.
17. Conlon R.A. Retinoic acid and pattern formation in vertebrates. Trends Genet. 11:1995;314-319.
18. Cordes S.P., Barsh G.S. The mouse segmentation gene kr encodes a novel basic domain-leucine zipper transcription factor. Cell. 79:1994;1025-1034.
19. Corwin J.T., Warchol M.E., Kelley M. Hair cell development. Curr. Op. Neurobiol. 3:1993;32-37.
20. D'Amico-Martel A., Noden D.M. Contributions of placodal and neural crest cells to avian peripheral ganglia. Am. J. Anat. 366:1983;445-468.
21. Daniotti J.L., Allende M.L., Weinberg E.S., Allende J.E. Cloning and expression of genes coding for protein kinase CK2 alpha and beta subunits in zebrafish (Danio rerio). Cell Mol. Biol. Res. 40:1994;431-439.
22. Deitcher D.L., Fekete D.M., Cepko C.L. Asymmetric expression of a novel homeobox gene in vertebrate sensory organs. J. Neurosci. 14:1994;486-498.
23. Deol M.S. The abnormalities in the inner ear in kreisler mice. J. Embryol. Exper. Morphol. 12:1964;475-490.
24. Deol M.S. Influence of neural tube on the differentiation of the inner ear in the mammalian embryo. Nature. 209:1966;219-220.
25. De la Pompa J.L., James D., Zeller R. Limb deformity proteins during avian neurulation and sense organ development. Dev. Dyn. 204:1995;156-167.
26. Dickson C., Peters G. Potential oncogene product related to growth factors. Nature. 326:1987;833.
27. Dirksen M.L., Morasso M.I., Sargent T.D., Jamrich M. Differential expression of a Distal-less homeobox gene Xdll-2 in ectodermal cell lineages. Mech. Dev. 46:1994;63-70.
28. Dolle P., Ruberte E., Leroy P., Morriss-Kay G., Chambon P. Retinoic acid receptors, cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development. 110:1990;1133-1151.
29. Dolle O., Fraulob V., Kastner P., Chambon P. Developmental expression of murine retinoid X receptor (RXR) genes. Mech. Dev. 45:1994;91-104.
30. Eichmann, A., Sieweke, M., Grapin-Botton, A., Kelly, L., Graf, T., Le Dourain, N.M., 1997. The expression pattern of the mafB/kreisler gene in birds and mice reveals that the kreisler phenotype does not represent null mutant. Mech. Dev. (in press).
31. Ekker M., Akimenko M.A., Bremiller R., Westerfield M. Regional expression of three homeobox transcripts in the inner ear of zebrafish embryos. Neuron. 9:1992;27-35.
32. Enfors P., Van de Water T., Loring J., Jaenich R. Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron. 14:1995;1153-1164.
33. 2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell. 67:1991;767-774.
34. Erichsen S., Bagger-Sjoback D., Curtis L., Zuo J., Rarey K., Hultcrantz M. Appearance of glucocorticoid receptors in the inner ear of the mouse during development. Acta Otolaryngol. (Stockh.). 116:1996;721-725.
35. Erkman L., McEvilly R.J., Lou L., Ryan A.K., Hooshmand F., O'Connell S.M., Keithley E.M., Rapaport D.H., Ryan A.F., Rosenfeld M.G. Role of transcription factors BRN3.1 and Brn3.2 in auditory and visual system development. Nature. 381:1996;603-606.
36. Fekete D.M. Cell fate specification in the inner ear. Curr. Op. Neurobiol. 6:1996;533-541.
37. Fekete, D.M., Muthukumar, S., Karagoeos, D., 1995. Hair cells and supporting cells share a common progenitor in the chicken basilar papilla: retrovirus-based lineage analysis. In: The Molecular Biology of Hearing and Deafness, Abstract Book, p1.
38. Forrest D., Erway L.C., Ng L., Altschuler R., Curan T. Thyroid hormone receptor beta is essential for development of auditory function. Nature Genet. 13:1996;354-357.
39. Franklin J.I., Sargent T.D. Ventral neural cadherin, a novel cadherin expressed in a subset of neural tissues in the zebrafish embryo. Dev. Dyn. 206:1996;121-130.
40. Franz D.A., Liu W., Williams J.D., Hatcher V., Galinovic-Schwartz V., Flanders K.C., Van de Water T.R. Induction of chondrogenesis: requirement for synergistic interaction of basic fibroblast growth factor and transforming growth factor-beta. Development. 120:1994;415-424.
41. Friesel R., Brown S.A.N. Spatially restricted expression of fibroblast growth factor receptor-2 during Xenopus development. Development. 116:1992;1051-1058.
42. Fritzsh B., Silos-Santiago I., Bianchi L.M., Fariñas I. The role of neurotrophic factors in regulating the development of the ear. Trends Neurosci. 20:1997;159-164.
43. Frohman M.A., Martin G.R., Cordes S.P., Halamek L.P., Barsch G.S. Altered rhombomere-specific gene expression and hyoid bone differentiation in the mouse segmentation mutant, kreisler (kr). Development. 117:1993;925-936.
44. Gale N.W., Holland S.J., Valenzuela D., Flenniken A., Pan L., Ryan T.E., Henkemeyer M., Strebhardt K., Hirai H., Wilkinson D., Pawson T., Davis S., Yancopoulos G.D. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron. 17:1996;9-19.
45. Gallagher B.C., Jonathan J.H., Grainger R.M. Inductive processes leading to inner ear formation during Xenopus development. Dev. Biol. 175:1996;95-107.
46. Garrido J.J., Alonso M.T., Lim F., Represa J., Giraldez F., Schimmang T. Using herpes simplex virus type 1 (HSV-1) mediated gene transfer to study neurotrophins in cochlear neurons. Intl. J. Dev. Biol. Suppl. 1:1996;149S-150S.
47. Goodyear R., Holley M., Richardson G. Hair and supporting-cell differentiation during development of the avian inner ear. J. Comp. Neurol. 351:1995;81-93.
48. Goulding M.D., Chalepakis G., Deutsch U., Erselius J., Gruss P. Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J. 10:1991;1135-1147.
49. Hadrys, T., Braun, T., Rinkwitz-Brandt, S., Arnold, H.H., Bober, E., 1998. Nkx5-1 controls semicircular canal formation in the mouse inner ear. Development 125, 33-39.
50. Haffter P., Granato M., Brand M., Mullins M.C., Hammerschmidt M., Kane D.A., Odenthal J., van Eeden F.J.M., Jiang Y.J., Heisenberg C.P., Kelsh R.N., Furutani-Seiki M., Vogelsang E., Beuchle D., Schach U., Fabian C., Nusslein-Volhard C. The identification of genes with unique and essential functions in the development of the zebrafish. Danio rerio. Development. 123:1996;1-36.
51. Hadler G., Callaerts P., Gehring W.J. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science. 267:1995;1788-1792.
52. Hallböök F., Ibañez C.F., Ebendal T., Persson H. Cellular localization of Brain-Derived Neurotrophic Factor and Neurotrophin-3 messenger RNA expression in the early chicken embryo. Eur. J. Neurosci. 1:1993;1-14.
53. Harrison R.G. Relations of symmetry in the developing embryo. Trans. Conn. Acad. Arts Sci. 36:1945;277-330.
54. Hemond S.G., Morest D.K. Effects of otic epithelium on cochleo-vestibular ganglion fiber growth in vitro. Anat. Rec. 232:1992;273-284.
55. Hertwig, P., 1944. Die Genese de Hirn- und Gehörorganmissbildungen bei röntgenmutierten Kreisler-Mäusen. Z. KonstLehre 28, 327-354.
56. Hollyday M., McMahon J.A., McMahon A.P. Wnt expression patterns in chick embryo nervous system. Mech. Dev. 52:1995;9-25.
57. Ishii N., Wanaka A., Ohno K., Matsumoto K., Eguchi Y., Mori T., Tsujimoto Y., Tohyama M. Localization of bcl-2, bax, and bcl-x mRNAs in the developing inner ear of the mouse. Brain Res. 726:1996;123-128.
58. Jacobson A.G. The determination and positioning of the nose, lens and ear. J. Exp. Zool. 154:1963;273-303.
59. Jacobson A.G. Inductive processes in embryonic development. Science. 152:1966;25-34.
60. Jan, Y.N., Jan, L.Y., 1993. The peripheral nervous system. In: Bate, M., Martínez-Arias, A. (Eds.), The Development of Drosophila melanogaster. Cold Spring Harbor Laboratory Press, pp. 1207-1244.
61. Jiménez C., Represa J., Giraldez F., García-Díaz X. Calcium currents in dissociated cochlear neurons from the chick embryo and their modification by neurotrophin-3. Neuroscience. 77:1996;673-682.
62. Jiménez C., Nuñez L. Glutamate receptors in the developing cochlear ganglion. Intl. J. Dev. Biol. Suppl. 1:1996;149S-150S.
63. Kablar B., Vignali R., Menotti L., Pannese M., Andrezzoli M., Polo C., Giribaldi M.G., Boncinelli E., Barsacchi G. Xotx genes in the developing brain of Xenopus laevis. Mech. Dev. 55:1996;145-158.
64. Karavanov A.A., Saint-Jeannet J.P., Karavanova I., Taira M., Dawid I.B. The LIM homeodomain protein Lim-1 is widely expressed in neural, neural crest and mesoderm derivatives in vertebrate development. Intl. J. Dev. Biol. 40:1996;453-461.
65. Karperien M., Lanser P., de Laat S.W., Boonstra J., Defize L.H. Parathyroid hormone related peptide mRNA expression during murine postimplantation development: evidence for involvement in multiple differentiation processes. Intl. J. Dev. Biol. 40:1996;599-608.
66. Kelley M.W., Xiao-Mei X., Wagner M.A., Warchol M.E., Corwin J.T. The developing organ of Corti contains retinoid acid and forms supernumerary hair cells in response to exogenous retinoid acid in culture. Development. 119:1993;1041-1053.
67. Kinoshita N., Minshull J., Kirschner M.W. The identification of two novel ligands of the fgf receptor by yeast screening method and their activity in Xenopus development. Cell. 83:1995;621-630.
68. Krauss S., Johansen T., Korzh V., Fjose A. Expression of the zebrafish paired box gene paxduring early neurogenesis. Development. 113:1991;1193-1206.
69. Lallier T.E., Whittaker C.A., DeSimone D.W. Integrin alpha 6 expression is required for early nervous system development in Xenopus laevis. Development. 122:1996;2539-2554.
70. Lele Z., Krone P.H. Expression of genes encoding the collagen-binding heat shock protein (Hsp47) and type II collagen in developing zebrafish embryos. Mech. Dev. 61:1997;89-98.
71. León, Y., Sánchez, J.A., Miner, C., McNaughton, L.M., Represa, J., Giraldez, F., 1995a. Developmental regulation of Fos protein during the proliferative growth of the otic vesicle. Dev. Biol. 167, 75-86.
72. León, Y., Vazquez, E., Sanz, C., Vega, J.A., Mato, J.M., Giraldez, F., Represa, J., Varela-Nieto, I., 1995b. Insulin-like Growth Factor-I regulates cell proliferation in the developing inner ear, activating glycosyl-phosphatidylinositol hydrolysis and Fos expression. Endocrinol. 136, 3494-3503.
73. Lindberg, K.H., VanDeRyt, J.T., Dressler, G.R., Barald, K.F., 1995. The cellular environment controls the expression of Pax-2 protein in the otocyst during development of the chick inner ear. In: The Molecular Biology of Hearing and Deafness, Abstract book, p26.
74. Li Y., Allende M.L., Filkelstein R., Weinberg E.S. Expression of two zebrafish orthodenticle-related genes in the embryonic brain. Mech. Dev. 48:1994;229-244.
75. Li C.W., Van de Water T.R., Ruben R.J. The fate of the eleventh and twelfth day mouse otocyst: an in vitro study of the sites of origin of the embryonic inner ear sensory structures. J. Morphol. 157:1978;249-268.
76. Maden M., Gale E., Kosteskii I., Zile M. Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Curr. Biol. 6:1996;417-426.
77. Mahamood R., Kiefer P., Gunthrie S., Dickson C., Mason I. Multiple roles for fgf-3 during cranial neural development in the chicken. Development. 121:1995;1399-1410.
78. Mansour S.L., Goddard J.M., Cappechi M.R. Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development. 117:1993;13-28.
79. Manzanares, M., Cordes, S., Kwan, CT, Sham, M.H., Barsh, G.S., Krumlauf, R., 1997. Segmental regulation of Hoxb-3 vy kreisler. Nature (in press).
80. Mark M., Lufkin T., Vonesch J.L., Ruberte E., Olivo J.C., Dollé P., Gorry P., Lumsden A., Chambon P. Two rhombomeres are altered in Hoxa-1 mutant mice. Development. 119:1993;319-338.
81. McKay I.J., Muchamore I., Krumlauf R., Maden M., Lumsden A., Lewis J. The kreisler mouse: a hindbrain segmentation mutant that lacks two rhombomeres. Development. 120:1994;2199-2211.
82. Mendelsohn C., Ruberte E., LeMeur M., Morriss-Kay G., Chambon P. Developmental analysis of the retinoic acid-inducible RAR-beta 2 promoter in transgenic animals. Development. 113:1991;723-734.
83. Minichiello L., Piehl F., Vázquez E., Schimmang T., Hökfelt T., Represa J., Klein R. Differential effect of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons. Development. 121:1995;4067-4075.
84. Morasso M.I., Mahon K.A., Sargent T.D. A Xenopus distal-less gene in transgenic mice: conserved regulation in distal limb epidermis and other sites of epithelial-mesenchymal interaction. Proc. Natl. Acad. Sci. USA. 92:1995;3968-3972.
85. More R., Casey G., Brookes S., Dixon M., Peters G., Dickson C. Sequence topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus. EMBO J. 5:1986;919-924.
86. Morgan J.I., Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Ann. Rev. Neurosci. 14:1991;421-451.
87. Myat A., Henrique D., Ish-Horowitz D., Lewis J. A chick homologue Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev. Biol. 174:1996;233-247.
88. Nieto M.A., Gilardi-Hebenstreit P., Charnay P., Wilkinson D.G. A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm. Development. 116:1992;1137-1150.
89. Ng L.J., Wheatley S., Muscat G.E., Conway-Campbell J., Bowles J., Wright E., Bell D.M., Tam P.P., Cheah K.S., Koopman P. SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev. Biol. 183:1997;108-121.
90. Noden, D.M., Van De Water, T.R., 1986. The developing ear: tissue origins and interactions. In: Ruben et al. (Eds.), The Biology of Change in Otolaryngology. Elsevier, Amsterdam, pp 15-46.
91. Nornes H.O., Dressler G.R., Knapik E.W., Deutsch U., Gruss P. Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development. 109:1990;797-809.
92. Nosrat C.A., Tomac A., Lindqvist E., Lindskog S., Humpel C., Stromberg I., Ebendal T., Hoffer B.J., Olson L. Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system. Cell Tissue Res. 286:1996;191-207.
93. Oh S.H., Johnson R., Wu D.K. Differential expression of bone morphogenetic proteins in the developing vestibular and auditory sensory organs. J. Neurosci. 16(20):1996;6463-6475.
94. Oliver G., Mailhos A., Wehr R., Copeland N.G., Jenkins N.A., Gruss P. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. Development. 121:1995;4045-4055.
95. Oliver G., Wehr R., Jenkins N.A., Copeland N.G., Cheyette B.N.R., Hartenstein V., Zipursky S.L., Gruss P. Homeobox genes and connective tissue patterning. Development. 121:1995;693-705.
96. Ott T., Kaestner K.H., Monaghan A.P., Schutz G. The mouse homolog of the region specific homeotic gene spalt of Drosophila is expressed in the developing nervous system and in mesoderm-derived structures. Mech. Dev. 56:1996;117-128.
97. Parr B.A., Shea M.J., Vassileva G., McMahon A.P. Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development. 119:1993;247-261.
98. Papalopulu N., Kintner C. Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. Development. 117:1993;961-975.
99. Peters G., Brookes S., Smith R., Dickson J.C. Tumorigenesis by mouse mammary tumour virus: evidence for a common region for provirus integration in mammary tumours. Cell. 33:1983;369-377.
100. Pirvola U., Ylikoski J., Palgi J., Lehtonen E., Arumae U., Saarma M. Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear ganglia. Proc. Natl. Acad. Sci. USA. 89:1992;9915-9919.
101. Quin F., Kirby M.L. int-2 influences the development of the nodose ganglion. Pediatr. Res. 38(4):1995;485-492.
102. Represa J., Miner C., Barbosa E., Giraldez F. Bombesin and other growth factors activate cell proliferation in chick embryo otic vesicles in culture. Development. 102:1988;87-91.
103. Represa J., Sanchez A., Miner C., Lewis J., Giraldez F. Retinoic acid modulation of the early development of the inner ear is associated with the control of c-fos expression. Development. 110:1990;1081-1090.
104. Represa, J., León, Y., Miner, C., Giraldez, F., 1991a. The proto-oncogene int-2 is responsible for induction of the inner ear. Nature 353, 561-563.
105. Represa, J., Avila, M.A., Miner, C., Giraldez, F., Romero, G., Clemente, R., Mato, J.M., Varela-Nieto, I., 1991b. Glycosyl-phosphatidylinositol/ inositol phosphoglycan: a signalling system for the low affinity nerve growth factor receptor. Proc. Natl. Acad. Sci. USA 88, 8016-8019.
106. Represa J., Avila M.A., Romero G., Mato J.M., Giraldez F., Varela-Nieto I. Neurotrophic factors regulate cell proliferation during inner ear development trough glycosyl-phosphatidylinositol hydrolysis. Dev. Biol. 159:1993;257-265.
107. Richardson G.P., Crossin K.L., Chuong C.M., Edelman G.M. Expression of cell adhesion molecules during embryonic induction. III. Development of the otic placode. Dev. Biol. 119:1987;217-230.
108. Rinkwitz-Brandt S., Justus M., Oldenettel I., Arnold H.H., Bober E. Distinct temporal expression of mouse Nkx5.1 and Nkx5.2 homeobox genes during brain and ear development. Mech. Dev. 52:1995;371-381.
109. Rinkwitz-Brandt, S., Arnold, H.H., Bober, E., 1996. Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development. Hearing Research 99, 129-138.
110. Robinson G.W., Mahon K.A. Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech. Dev. 48:1994;199-215.
111. Ruberte E., Friederich V., Morris-Kay G., Chambon P. Differential distribution of CRABP I and CRABP II transcripts during mouse embryogenesis. Development. 115:1992;973-987.
112. Ruberte E., Dolle P., Chambon P., Morris-Kay G., Chambon P. Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos. Development. 111:1991;45-60.
113. Russell W.L. Splotch, a new mutation in the house mouse Mus musculus. Genetics. 32:1947;107.
114. Ruberte E., Friederich V., Morris-Kay G., Chambon P. Differential distribution of CRABP I and CRABP II transcripts during mouse embryogenesis. Development. 115:1993;973-987.
115. San José, I., Vega, J.A., Atares, N., Carreres, J., Represa, J., 1997. Differential regulation of microfilament associated proteins (MAPs) by BDNF in the cochleo vestibular ganglion. Intl. J. Dev. (in press).
116. Schecterson L.C., Bothwell M. Neurotrophin and neurotrophin receptor mRNA expression in developing inner ear. Hear Res. 73:1994;92-100.
117. Schimmang T., Minchiello L., Vázquez E., San José I., Giráldez F., Klein R., Represa J. Developing inner ear sensory neurons require TrkB and TrkC receptors for innervation of their peripheral targets. Development. 121:1995;3381-3391.
118. Simeone A., Acampora D., Mallamaci A., Stornaiuolo A., D'Apice M.R., Nigro V., Boncinelli E. A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J. 12:1993;2735-2747.
119. Simeone A., Acampora D., Pannese M., D'Esposito M., Stornaiuolo A., Gulisano M., Mallamaci A., Kastury K., Druck T., Hueber K., Boncinelli E. Cloning and characterization of two members of the vertebrate Dlx gene family. Proc. Natl. Acad. Sci. USA. 91:1994;2250-2254.
120. Snider W.D. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us? Cell. 77:1994;627-638.
121. Stadler H.S., Solursh M. Characterization of the homeobox-containing gene GH6 identifies novel regions of homeobox gene expression in the developing chick embryo. Dev. Biol. 161:1994;251-262.
122. Steel K.P. Inherited hearing defects in mice. Ann. Rev. Genet. 29:1995;675-701.
123. Steel K.P., Brown D.M. Genes and deafness. Trends Genet. 10:1994;428-435.
124. Streeter G.L. On the development of the membranous labyrinth and the acoustic and facial nerves in the human embryo. Am. J. Anat. 6:1906;139-166.
125. Stone J.S., Leaño S.G., Baker L.P., Rubel E.W. Hair cell differentiation in chick cochlear epithelium after aminoglycoside toxicity: in vivo and in vitro observations. J. Neurosci. 16:1996;6157-6174.
126. Suzuki R., Padanilam B.J., Vitale E., Ramirez F., Solhursh M. Repeating developmental expression of G-Hox7, a novel Homeobox-containing gene in the chicken. Dev. Biol. 148:1991;375-388.
127. Swanson G.J., Howard M., Lewis J. Epithelial autonomy in the development of the inner ear of a bird embryo. Dev. Biol. 137:1990;243-257.
128. Tannahill D., Isaacs H.V., Close M.J., Peters G., Slack J.M.W. Developmental expression of the Xenopus int-2 (fgf-3) gene: activation by mesodermal and neural induction. Development. 115:1992;695-702.
129. Tashiro K., Tooi O., Nakamura H., Koga C., Ito Y., Hikasa H., Shiokawa K. Cloning and expression studies of cDNA for a novel Xenopus cadherin (XmN-cadherin), expressed maternally and later neural-specifically in embryogenesis. Mech. Dev. 54:1996;161-171.
130. Torres, M., Gómez-Pardo, E., Gruss, P., 1996. Pax2 Contributes to inner ear patterning and optic nerve trajectory. Development 121, 4057-4065.
131. Van de Water, T.R., Conley, X., 1982. Neural inductive message to the developing mammalian inner ear: contact mediated versus extracelular matrix interaction. Anat. Rec., 195A.
132. Varela-Nieto I., Represa J., Avila M.A., Miner C., Mato J.M., Giraldez F. Inositol phospho-oligosaccharide stimulates cell proliferation in the early developing inner ear. Dev. Biol. 143:1991;432-435.
133. Vazquez E., Van de Water T.R., Del Valle M., Vega J.A., Staeker H., Giraldez F., Represa J. Pattern of trkB protein-like immunoreactivity and in vitro effects of brain-derived neurotrophic factor on developing cochlear and vestibular neurons. Anat. Embryol. 189:1994;157-167.
134. Vazquez E., Geijo E., Schimmang T., Giraldez F. Compartmental structure of the otic placode: junctional permeability and clonal resriction. Intl. J. Dev. Suppl. 1:1996;236S-237S.
135. Vogel K.S., Davies A.M. Heterotopic transplantation of presumptive placodal ectoderm changes the fate of sensory neuron precursors. Development. 119:1993;263-276.
136. Von Bartheld, C.S., Patterson, S.L., Hener, J.G., Wheeler, E.F., Bothwell, M., Rubel, E., 1991. Expression of nerve growth factor (NGF) receptors in the developing inner ear of chicken and rat. Development 113, 455-470.
137. Waddington C.H. The determination of the auditory placode in the chick. J. Exp. Biol. 14:1937;232-239.
138. Walther C., Gruss P. Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 113:1991;1435-1449.
139. Wanake A., Milbrandt J., Johnson E.M. Expression of FGF receptor gene in rat development. Development. 111:1991;455-468.
140. Warchol M.E., Corwin J.T. Regenerative proliferation in organ cultures of the avian cochlea: identification of the initial progenitors and determination of the latency of the proliferative response. J. Neurosci. 16:1996;5466-5477.
141. Wasserman, K.M., Lewandosky, M., Campbell, K., Joyner, A.L., Rubenstein, J.L.R., Martínez, S., Martin, G., 1997. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organiser is dependent on Gbx2 gene function. Development (in press).
142. Whitfield T.T., Granato M., van Eeden F.J.M., Schach U., Brand M., Furutani-Seiki M., Haffter P., Hammerschmidt M., Heisenberg C.P., Jiang Y.J., Kane D.A., Kelsh R.N., Mullins M.C., Odenthal J., Nusslein-Volhard C. Mutations affecting the development of the zebrafish inner ear and lateral line. Development. 123:1996;241-254.
143. Wilkinson D.G., Peters G., Dickson C., McMahon A.P. Expression of the fgf-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J. 7:1988;691-695.
144. Wilkinson D.G., Peters G., Dickson C., McMahon A.P. Expression pattern of the fgf-related proto-oncogene int-2 suggests multiple roles in fetal development. Development. 105:1989;131-136.
145. Williams R., Backstrom A., Ebendal T., Hallbook F. Molecular cloning and cellular localization of trkC in the chicken embryo. Brain Res. Dev. Brain. Res. 75:1993;235-252.
146. Wu D.K., Oh S.H. Sensory organ generation in the chick inner ear. J. Neurosci. 16:1996;6454-6462.
147. Xu P.X., Woo I., Her H., Beier D.R., Maas R.L. Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development. 124:1997;219-231.
148. Yamaguchi T.O., Rossant J. Fibroblast growth factors in mammalian development. Curr. Op. Gen. Dev. 5:1995;485-491.
149. Yntema C.L. Experiments on the determination of the ear ectoderm in the embryo of amblyostoma punctatum. J. Exp. Zool. 65:1933;317-357.
150. Yntema C.L. An analysis of induction of the ear from foreign ectoderm in the salamander embryo. J. Exp. Zool. 113:1950;211-244.
151. Zimmerman J.E., Bui Q.T., Steingrimsson E., Nagle D.L., Fu W., Genin A., Spinner N.B., Copeland N.G., Jenkins N.A., Bucan M., Bonini N.M. Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene. Genome Res. 7:1997;128-141.