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Volumn 241, Issue 4, 2012, Pages 741-758

A novel method for retinoic acid administration reveals differential and dose-dependent downregulation of Fgf3 in the developing inner ear and anterior CNS

Author keywords

Fibroblast growth factor signaling; Gavage; Hindbrain; Inner ear; Retinoic acid

Indexed keywords

FIBROBLAST GROWTH FACTOR 3; RETINOIC ACID; SUGAR;

EID: 84858285164     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.23748     Document Type: Article
Times cited : (10)

References (79)
  • 1
    • 18144372714 scopus 로고    scopus 로고
    • Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alpha
    • Abbott BD, Best DS, Narotsky MG. 2005. Teratogenic effects of retinoic acid are modulated in mice lacking expression of epidermal growth factor and transforming growth factor-alpha. Birth Defects Res A Clin Mol Teratol 73: 204-217.
    • (2005) Birth Defects Res A Clin Mol Teratol , vol.73 , pp. 204-217
    • Abbott, B.D.1    Best, D.S.2    Narotsky, M.G.3
  • 2
    • 56849097809 scopus 로고    scopus 로고
    • Retinoic acid affects craniofacial patterning by changing Fgf8 expression in the pharyngeal ectoderm
    • Abe M, Maeda T, Wakisaka S. 2008. Retinoic acid affects craniofacial patterning by changing Fgf8 expression in the pharyngeal ectoderm. Dev Growth Differ 50: 717-729.
    • (2008) Dev Growth Differ , vol.50 , pp. 717-729
    • Abe, M.1    Maeda, T.2    Wakisaka, S.3
  • 3
    • 0024441643 scopus 로고
    • Retinoic-acid-induced limb-reduction defects: perturbation of zones of programmed cell death as a pathogenetic mechanism
    • Alles AJ, Sulik KK. 1989. Retinoic-acid-induced limb-reduction defects: perturbation of zones of programmed cell death as a pathogenetic mechanism. Teratology 40: 163-171.
    • (1989) Teratology , vol.40 , pp. 163-171
    • Alles, A.J.1    Sulik, K.K.2
  • 6
    • 0030010613 scopus 로고    scopus 로고
    • Retinoic acid induces stage-specific repatterning of the rostral central nervous system
    • Avantaggiato V, Acampora D, Tuorto F, Simeone A. 1996. Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Dev Biol 175: 347-357.
    • (1996) Dev Biol , vol.175 , pp. 347-357
    • Avantaggiato, V.1    Acampora, D.2    Tuorto, F.3    Simeone, A.4
  • 7
    • 78651090768 scopus 로고    scopus 로고
    • Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear
    • Bok J, Raft S, Kong KA, Koo SK, Drager UC, Wu DK. 2011. Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear. Proc Natl Acad Sci USA 108: 161-166.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 161-166
    • Bok, J.1    Raft, S.2    Kong, K.A.3    Koo, S.K.4    Drager, U.C.5    Wu, D.K.6
  • 9
    • 4444221165 scopus 로고    scopus 로고
    • Dose-response for retinoic acid-induced forelimb malformations and cleft palate: a comparison of computerized image analysis and visual inspection
    • Campbell JL Jr, Smith MA, Fisher JW, Warren DA. 2004. Dose-response for retinoic acid-induced forelimb malformations and cleft palate: a comparison of computerized image analysis and visual inspection. Birth Defects Res B Dev Reprod Toxicol 71: 289-295.
    • (2004) Birth Defects Res B Dev Reprod Toxicol , vol.71 , pp. 289-295
    • Campbell Jr, J.L.1    Smith, M.A.2    Fisher, J.W.3    Warren, D.A.4
  • 10
    • 0032400471 scopus 로고    scopus 로고
    • The differential sensitivities of inner ear structures to retinoic acid during development
    • Choo D, Sanne JL, Wu DK. 1998. The differential sensitivities of inner ear structures to retinoic acid during development. Dev Biol 204: 136-150.
    • (1998) Dev Biol , vol.204 , pp. 136-150
    • Choo, D.1    Sanne, J.L.2    Wu, D.K.3
  • 11
    • 0026491183 scopus 로고
    • Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo
    • Conlon RA, Rossant J. 1992. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development 116: 357-368.
    • (1992) Development , vol.116 , pp. 357-368
    • Conlon, R.A.1    Rossant, J.2
  • 12
    • 0021914763 scopus 로고
    • Spontaneous and retinoic acid-induced postaxial polydactyly in mice
    • Cusic AM, Dagg CP. 1985. Spontaneous and retinoic acid-induced postaxial polydactyly in mice. Teratology 31: 49-59.
    • (1985) Teratology , vol.31 , pp. 49-59
    • Cusic, A.M.1    Dagg, C.P.2
  • 13
    • 0031773906 scopus 로고    scopus 로고
    • Role of TGF-beta in RA-induced cleft palate in CD-1 mice
    • Degitz SJ, Morris D, Foley GL, Francis BM. 1998. Role of TGF-beta in RA-induced cleft palate in CD-1 mice. Teratology 58: 197-204.
    • (1998) Teratology , vol.58 , pp. 197-204
    • Degitz, S.J.1    Morris, D.2    Foley, G.L.3    Francis, B.M.4
  • 14
    • 0021032905 scopus 로고
    • Early morphological abnormalities in splotch mouse embryos and predisposition to gene- and retinoic acid-induced neural tube defects
    • Dempsey EE, Trasler DG. 1983. Early morphological abnormalities in splotch mouse embryos and predisposition to gene- and retinoic acid-induced neural tube defects. Teratology 28: 461-472.
    • (1983) Teratology , vol.28 , pp. 461-472
    • Dempsey, E.E.1    Trasler, D.G.2
  • 15
    • 68049118709 scopus 로고    scopus 로고
    • Developmental expression of retinoic acid receptors (RARs)
    • Dolle P. 2009. Developmental expression of retinoic acid receptors (RARs). Nucl Recept Signal 7: e006.
    • (2009) Nucl Recept Signal , vol.7
    • Dolle, P.1
  • 16
    • 51549116267 scopus 로고    scopus 로고
    • Retinoic acid synthesis and signaling during early organogenesis
    • Duester G. 2008. Retinoic acid synthesis and signaling during early organogenesis. Cell 134: 921-931.
    • (2008) Cell , vol.134 , pp. 921-931
    • Duester, G.1
  • 17
    • 0026669144 scopus 로고
    • Spina bifida aperta induced by valproic acid and by all-trans-retinoic acid in the mouse: distinct differences in morphology and periods of sensitivity
    • Ehlers K, Sturje H, Merker HJ, Nau H. 1992. Spina bifida aperta induced by valproic acid and by all-trans-retinoic acid in the mouse: distinct differences in morphology and periods of sensitivity. Teratology 46: 117-130.
    • (1992) Teratology , vol.46 , pp. 117-130
    • Ehlers, K.1    Sturje, H.2    Merker, H.J.3    Nau, H.4
  • 18
    • 0033145082 scopus 로고    scopus 로고
    • RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid
    • Folberg A, Nagy Kovacs E, Luo J, Giguere V, Featherstone MS. 1999. RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid. Dev Dyn 215: 96-107.
    • (1999) Dev Dyn , vol.215 , pp. 96-107
    • Folberg, A.1    Nagy Kovacs, E.2    Luo, J.3    Giguere, V.4    Featherstone, M.S.5
  • 19
    • 0031446469 scopus 로고    scopus 로고
    • Effect of retinoic acid on otic capsule chondrogenesis in high density culture suggests disruption of epithelial-mesenchymal interactions
    • Frenz D, Liu W. 1997. Effect of retinoic acid on otic capsule chondrogenesis in high density culture suggests disruption of epithelial-mesenchymal interactions. Teratology 56: 233-240.
    • (1997) Teratology , vol.56 , pp. 233-240
    • Frenz, D.1    Liu, W.2
  • 20
    • 0034076178 scopus 로고    scopus 로고
    • Treatment with all-trans-retinoic acid decreases levels of endogenous TGF-beta(1) in the mesenchyme of the developing mouse inner ear
    • Frenz DA, Liu W. 2000. Treatment with all-trans-retinoic acid decreases levels of endogenous TGF-beta(1) in the mesenchyme of the developing mouse inner ear. Teratology 61: 297-304.
    • (2000) Teratology , vol.61 , pp. 297-304
    • Frenz, D.A.1    Liu, W.2
  • 23
  • 24
    • 34447500463 scopus 로고    scopus 로고
    • Changes in retinoic acid signaling alter otic patterning
    • Hans S, Westerfield M. 2007. Changes in retinoic acid signaling alter otic patterning. Development 134: 2449-2458.
    • (2007) Development , vol.134 , pp. 2449-2458
    • Hans, S.1    Westerfield, M.2
  • 25
    • 0001323773 scopus 로고
    • Relations of symmetry in the developing ear of amblystoma punctatum
    • Harrison RG. 1936. Relations of symmetry in the developing ear of amblystoma punctatum. Proc Natl Acad Sci USA 22: 238-247.
    • (1936) Proc Natl Acad Sci USA , vol.22 , pp. 238-247
    • Harrison, R.G.1
  • 26
    • 0034988903 scopus 로고    scopus 로고
    • Retinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopod
    • Hayes C, Morriss-Kay GM. 2001. Retinoic acid specifically downregulates Fgf4 and inhibits posterior cell proliferation in the developing mouse autopod. J Anat 198: 561-568.
    • (2001) J Anat , vol.198 , pp. 561-568
    • Hayes, C.1    Morriss-Kay, G.M.2
  • 27
    • 77953193898 scopus 로고    scopus 로고
    • A spoonful of sugar helps the medicine go down: a novel technique to improve oral gavage in mice
    • Hoggatt A, Hoggatt J, Honerlaw M, Pelus LM. 2010. A spoonful of sugar helps the medicine go down: a novel technique to improve oral gavage in mice. JAALAS 49: 329-334.
    • (2010) JAALAS , vol.49 , pp. 329-334
    • Hoggatt, A.1    Hoggatt, J.2    Honerlaw, M.3    Pelus, L.M.4
  • 28
    • 77957680809 scopus 로고    scopus 로고
    • Taming anxiety in laboratory mice
    • Hurst J, West R. 2010. Taming anxiety in laboratory mice. Nature Methods 7: 825-826.
    • (2010) Nature Methods , vol.7 , pp. 825-826
    • Hurst, J.1    West, R.2
  • 30
    • 0030949889 scopus 로고    scopus 로고
    • Contribution of retinoic acid receptor gamma to retinoid-induced craniofacial and axial defects
    • Iulianella A, Lohnes D. 1997. Contribution of retinoic acid receptor gamma to retinoid-induced craniofacial and axial defects. Dev Dyn 209: 92-104.
    • (1997) Dev Dyn , vol.209 , pp. 92-104
    • Iulianella, A.1    Lohnes, D.2
  • 31
    • 0023936633 scopus 로고
    • Histological comparison of the effects of the splotch gene and retinoic acid on the closure of the mouse neural tube
    • Kapron-Bras CM, Trasler DG. 1988. Histological comparison of the effects of the splotch gene and retinoic acid on the closure of the mouse neural tube. Teratology 37: 389-399.
    • (1988) Teratology , vol.37 , pp. 389-399
    • Kapron-Bras, C.M.1    Trasler, D.G.2
  • 33
    • 0346025629 scopus 로고    scopus 로고
    • Axial skeletal and Hox expression domain alterations induced by retinoic acid, valproic acid, and bromoxynil during murine development
    • Kawanishi CY, Hartig P, Bobseine KL, Schmid J, Cardon M, Massenburg G, Chernoff N. 2003. Axial skeletal and Hox expression domain alterations induced by retinoic acid, valproic acid, and bromoxynil during murine development. J Biochem Mol Toxicol 17: 346-356.
    • (2003) J Biochem Mol Toxicol , vol.17 , pp. 346-356
    • Kawanishi, C.Y.1    Hartig, P.2    Bobseine, K.L.3    Schmid, J.4    Cardon, M.5    Massenburg, G.6    Chernoff, N.7
  • 34
    • 0027493926 scopus 로고
    • The developing organ of Corti contains retinoic acid and forms supernumerary hair cells in response to exogenous retinoic acid in culture
    • Kelley MW, Xu X-M, Wagner MA, Warchol ME, Corwin JT. 1993. The developing organ of Corti contains retinoic acid and forms supernumerary hair cells in response to exogenous retinoic acid in culture. Development 119: 1041-1053.
    • (1993) Development , vol.119 , pp. 1041-1053
    • Kelley, M.W.1    Xu, X.-M.2    Wagner, M.A.3    Warchol, M.E.4    Corwin, J.T.5
  • 35
    • 0015785215 scopus 로고
    • Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid
    • Kochhar DM. 1973. Limb development in mouse embryos. I. Analysis of teratogenic effects of retinoic acid. Teratology 7: 289-298.
    • (1973) Teratology , vol.7 , pp. 289-298
    • Kochhar, D.M.1
  • 36
    • 0021592919 scopus 로고
    • Comparative teratogenic activities of two retinoids: effects on palate and limb development
    • Kochhar DM, Penner JD, Tellone CI. 1984. Comparative teratogenic activities of two retinoids: effects on palate and limb development. Teratog Carcinog Mutagen 4: 377-387.
    • (1984) Teratog Carcinog Mutagen , vol.4 , pp. 377-387
    • Kochhar, D.M.1    Penner, J.D.2    Tellone, C.I.3
  • 37
    • 0032764419 scopus 로고    scopus 로고
    • Determination of the optimal time and dosage of all-trans retinoic acid for induction of murine exencephaly
    • Kuno N, Kadomatsu K, Muramatsu T. 1999. Determination of the optimal time and dosage of all-trans retinoic acid for induction of murine exencephaly. Teratology 60: 63-67.
    • (1999) Teratology , vol.60 , pp. 63-67
    • Kuno, N.1    Kadomatsu, K.2    Muramatsu, T.3
  • 38
    • 0019239355 scopus 로고
    • Estimation of creatine phosphokinase and hydroxyproline in the developing limb: its use in evaluating the effect of teratogens on myogenesis and chondrogenesis
    • Kwasigroch TE, Neubert D. 1980. Estimation of creatine phosphokinase and hydroxyproline in the developing limb: its use in evaluating the effect of teratogens on myogenesis and chondrogenesis. Teratog Carcinog Mutagen 1: 181-191.
    • (1980) Teratog Carcinog Mutagen , vol.1 , pp. 181-191
    • Kwasigroch, T.E.1    Neubert, D.2
  • 39
    • 0021167320 scopus 로고
    • Mouse limb bud development in submerged culture: quantitative assessment of the effects of in vivo exposure to retinoic acid
    • Kwasigroch TE, Skalko RG, Church JK. 1984. Mouse limb bud development in submerged culture: quantitative assessment of the effects of in vivo exposure to retinoic acid. Teratog Carcinog Mutagen 4: 311-326.
    • (1984) Teratog Carcinog Mutagen , vol.4 , pp. 311-326
    • Kwasigroch, T.E.1    Skalko, R.G.2    Church, J.K.3
  • 40
    • 32444444859 scopus 로고    scopus 로고
    • Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 mice
    • Lee GS, Liao X, Cantor RM, Collins MD. 2006. Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 mice. Birth Defects Res A Clin Mol Teratol 76: 19-28.
    • (2006) Birth Defects Res A Clin Mol Teratol , vol.76 , pp. 19-28
    • Lee, G.S.1    Liao, X.2    Cantor, R.M.3    Collins, M.D.4
  • 41
    • 0028913872 scopus 로고
    • Anteriorization of CRABP-I expression by retinoic acid in the developing mouse central nervous system and its relationship to teratogenesis
    • Leonard L, Horton C, Maden M, Pizzey JA. 1995. Anteriorization of CRABP-I expression by retinoic acid in the developing mouse central nervous system and its relationship to teratogenesis. Dev Biol 168: 514-528.
    • (1995) Dev Biol , vol.168 , pp. 514-528
    • Leonard, L.1    Horton, C.2    Maden, M.3    Pizzey, J.A.4
  • 42
    • 43049124793 scopus 로고    scopus 로고
    • Retinoic acid-induced inner ear teratogenesis caused by defective Fgf3/Fgf10-dependent Dlx5 signaling
    • Liu W, Levi G, Shanske A, Frenz DA. 2008. Retinoic acid-induced inner ear teratogenesis caused by defective Fgf3/Fgf10-dependent Dlx5 signaling. Birth Defects Res B Dev Reprod Toxicol 83: 134-144.
    • (2008) Birth Defects Res B Dev Reprod Toxicol , vol.83 , pp. 134-144
    • Liu, W.1    Levi, G.2    Shanske, A.3    Frenz, D.A.4
  • 43
    • 0021592097 scopus 로고
    • Fetal hydrocephalus and ear anomalies associated with maternal use of isotretinoin
    • Lott IT, Bocian M, Pribram HW, Leitner M. 1984. Fetal hydrocephalus and ear anomalies associated with maternal use of isotretinoin. J Pediatr 105: 597-600.
    • (1984) J Pediatr , vol.105 , pp. 597-600
    • Lott, I.T.1    Bocian, M.2    Pribram, H.W.3    Leitner, M.4
  • 44
    • 0030005342 scopus 로고    scopus 로고
    • Expression of Fgf-3 in relation to hindbrain segmentation, otic pit position and pharyngeal arch morphology in normal and retinoic acid-exposed mouse embryos
    • Mahmood R, Mason IJ, Morriss-Kay GM. 1996. Expression of Fgf-3 in relation to hindbrain segmentation, otic pit position and pharyngeal arch morphology in normal and retinoic acid-exposed mouse embryos. Anat Embryol (Berl) 194: 13-22.
    • (1996) Anat Embryol (Berl) , vol.194 , pp. 13-22
    • Mahmood, R.1    Mason, I.J.2    Morriss-Kay, G.M.3
  • 45
    • 0030865243 scopus 로고    scopus 로고
    • Segmental identity can change independently in the hindbrain and rhombencephalic neural crest
    • Mallo M, Brandlin I. 1997. Segmental identity can change independently in the hindbrain and rhombencephalic neural crest. Dev Dyn 210: 146-156.
    • (1997) Dev Dyn , vol.210 , pp. 146-156
    • Mallo, M.1    Brandlin, I.2
  • 46
    • 0027500633 scopus 로고
    • Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear
    • Mansour SL, Goddard JM, Capecchi MR. 1993. Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development 117:13-28.
    • (1993) Development , vol.117 , pp. 13-28
    • Mansour, S.L.1    Goddard, J.M.2    Capecchi, M.R.3
  • 47
    • 66849101522 scopus 로고    scopus 로고
    • Function of retinoic acid receptors during embryonic development
    • Mark M, Ghyselinck NB, Chambon P. 2009. Function of retinoic acid receptors during embryonic development. Nucl Recept Signal 7: e002.
    • (2009) Nucl Recept Signal , vol.7
    • Mark, M.1    Ghyselinck, N.B.2    Chambon, P.3
  • 48
    • 0027103903 scopus 로고
    • Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity
    • Marshall H, Nonchev S, Sham MH, Muchamore I, Lumsden A, Krumlauf R. 1992. Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identity. Nature 360: 737-741.
    • (1992) Nature , vol.360 , pp. 737-741
    • Marshall, H.1    Nonchev, S.2    Sham, M.H.3    Muchamore, I.4    Lumsden, A.5    Krumlauf, R.6
  • 49
    • 0030005799 scopus 로고    scopus 로고
    • The role of Fgf-3 in early inner ear development: An analysis in normal and kreisler mutant mice
    • McKay I, Lewis J, Lumsden A. 1996. The role of Fgf-3 in early inner ear development: An analysis in normal and kreisler mutant mice. Dev Biol 174: 370-378.
    • (1996) Dev Biol , vol.174 , pp. 370-378
    • McKay, I.1    Lewis, J.2    Lumsden, A.3
  • 50
    • 33750095436 scopus 로고    scopus 로고
    • Effect of restraint and injection methods on heart rate and body temperature in mice
    • Meijer MK, Spruijt BM, van Zutphen LF, Baumans V. 2006. Effect of restraint and injection methods on heart rate and body temperature in mice. Lab Anim 40: 382-391.
    • (2006) Lab Anim , vol.40 , pp. 382-391
    • Meijer, M.K.1    Spruijt, B.M.2    van Zutphen, L.F.3    Baumans, V.4
  • 51
    • 0025733962 scopus 로고
    • Effects of retinoic acid excess on expression of Hox-2.9 and Krox-20 and on morphological segmentation in the hindbrain of mouse embryos
    • Morriss-Kay GM, Murphy P, Hill RE, Davidson DR. 1991. Effects of retinoic acid excess on expression of Hox-2.9 and Krox-20 and on morphological segmentation in the hindbrain of mouse embryos. EMBO J 10: 2985-2995.
    • (1991) EMBO J , vol.10 , pp. 2985-2995
    • Morriss-Kay, G.M.1    Murphy, P.2    Hill, R.E.3    Davidson, D.R.4
  • 52
    • 0033808942 scopus 로고    scopus 로고
    • Effects of excess vitamin A on development of cranial neural crest-derived structures: a neonatal and embryologic study
    • Mulder GB, Manley N, Grant J, Schmidt K, Zeng W, Eckhoff C, Maggio-Price L. 2000. Effects of excess vitamin A on development of cranial neural crest-derived structures: a neonatal and embryologic study. Teratology 62: 214-226.
    • (2000) Teratology , vol.62 , pp. 214-226
    • Mulder, G.B.1    Manley, N.2    Grant, J.3    Schmidt, K.4    Zeng, W.5    Eckhoff, C.6    Maggio-Price, L.7
  • 54
    • 0032077830 scopus 로고    scopus 로고
    • Developmental eye abnormalities in mouse fetuses induced by retinoic acid
    • Ozeki H, Shirai S. 1998. Developmental eye abnormalities in mouse fetuses induced by retinoic acid. Jpn J Ophthalmol 42: 162-167.
    • (1998) Jpn J Ophthalmol , vol.42 , pp. 162-167
    • Ozeki, H.1    Shirai, S.2
  • 56
    • 2142808843 scopus 로고    scopus 로고
    • Regulatory analysis of the mouse Fgf3 gene: Identification of an enhancer that mediates embryonic expression patterns and its partial dependence upon sonic hedgehog (Shh) signalling
    • Powles N, Marshall H, Economou A, Chiang C, Murakami A, Dickson C, Krumlauf R, Maconochie M. 2004. Regulatory analysis of the mouse Fgf3 gene: Identification of an enhancer that mediates embryonic expression patterns and its partial dependence upon sonic hedgehog (Shh) signalling. Dev Dyn 230: 44-68.
    • (2004) Dev Dyn , vol.230 , pp. 44-68
    • Powles, N.1    Marshall, H.2    Economou, A.3    Chiang, C.4    Murakami, A.5    Dickson, C.6    Krumlauf, R.7    Maconochie, M.8
  • 57
    • 78751526821 scopus 로고    scopus 로고
    • Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear
    • Radosevic M, Robert-Moreno A, Coolen M, Bally-Cuif L, Alsina B. 2011. Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear. Development 138: 397-408.
    • (2011) Development , vol.138 , pp. 397-408
    • Radosevic, M.1    Robert-Moreno, A.2    Coolen, M.3    Bally-Cuif, L.4    Alsina, B.5
  • 58
    • 0041935939 scopus 로고    scopus 로고
    • National Institute of Health, Bethesda, Maryland, USA:
    • Rasband W. 1997. ImageJ. National Institute of Health, Bethesda, Maryland, USA:
    • (1997) ImageJ
    • Rasband, W.1
  • 59
    • 0029064965 scopus 로고
    • Enhancement of the teratogenicity of all-trans-retinoic acid by maternal restraint stress in mice as a function of treatment timing
    • Rasco JF, Hood RD. 1995a. Enhancement of the teratogenicity of all-trans-retinoic acid by maternal restraint stress in mice as a function of treatment timing. Teratology 51: 63-70.
    • (1995) Teratology , vol.51 , pp. 63-70
    • Rasco, J.F.1    Hood, R.D.2
  • 60
    • 0029052943 scopus 로고
    • Maternal restraint stress-enhanced teratogenicity of all-trans-retinoic acid in CD-1 mice
    • Rasco JF, Hood RD. 1995b. Maternal restraint stress-enhanced teratogenicity of all-trans-retinoic acid in CD-1 mice. Teratology 51: 57-62.
    • (1995) Teratology , vol.51 , pp. 57-62
    • Rasco, J.F.1    Hood, R.D.2
  • 62
    • 1842837852 scopus 로고    scopus 로고
    • The retinoic acid receptors RARalpha and RARgamma are required for inner ear development
    • Romand R, Hashino E, Dolle P, Vonesch JL, Chambon P, Ghyselinck NB. 2002. The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev 119: 213-223.
    • (2002) Mech Dev , vol.119 , pp. 213-223
    • Romand, R.1    Hashino, E.2    Dolle, P.3    Vonesch, J.L.4    Chambon, P.5    Ghyselinck, N.B.6
  • 63
    • 33745303735 scopus 로고    scopus 로고
    • Retinoid signaling in inner ear development
    • Romand R, Dolle P, Hashino E. 2006a. Retinoid signaling in inner ear development. J Neurobiol 66: 687-704.
    • (2006) J Neurobiol , vol.66 , pp. 687-704
    • Romand, R.1    Dolle, P.2    Hashino, E.3
  • 64
    • 33645967476 scopus 로고    scopus 로고
    • Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear
    • Romand R, Kondo T, Fraulob V, Petkovich M, Dolle P, Hashino E. 2006b. Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear. J Comp Neurol 496: 643-654.
    • (2006) J Comp Neurol , vol.496 , pp. 643-654
    • Romand, R.1    Kondo, T.2    Fraulob, V.3    Petkovich, M.4    Dolle, P.5    Hashino, E.6
  • 65
    • 34250341329 scopus 로고    scopus 로고
    • Altered localization of gene expression in both ectoderm and mesoderm is associated with a murine strain difference in retinoic acid-induced forelimb ectrodactyly
    • Shimizu H, Lee GS, Beedanagari SR, Collins MD. 2007. Altered localization of gene expression in both ectoderm and mesoderm is associated with a murine strain difference in retinoic acid-induced forelimb ectrodactyly. Birth Defects Res A Clin Mol Teratol 79: 465-482.
    • (2007) Birth Defects Res A Clin Mol Teratol , vol.79 , pp. 465-482
    • Shimizu, H.1    Lee, G.S.2    Beedanagari, S.R.3    Collins, M.D.4
  • 68
    • 0029129462 scopus 로고
    • Teratogenicity of low doses of all-trans retinoic acid in presomite mouse embryos
    • Sulik KK, Dehart DB, Rogers JM, Chernoff N. 1995. Teratogenicity of low doses of all-trans retinoic acid in presomite mouse embryos. Teratology 51: 398-403.
    • (1995) Teratology , vol.51 , pp. 398-403
    • Sulik, K.K.1    Dehart, D.B.2    Rogers, J.M.3    Chernoff, N.4
  • 69
    • 0028929844 scopus 로고
    • Altered gene expression in murine branchial arches following in utero exposure to retinoic acid
    • Taylor LE, Bennett GD, Finnell RH. 1995. Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol 15: 13-25.
    • (1995) J Craniofac Genet Dev Biol , vol.15 , pp. 13-25
    • Taylor, L.E.1    Bennett, G.D.2    Finnell, R.H.3
  • 70
    • 0037378477 scopus 로고    scopus 로고
    • Retinoic acid repression of bone morphogenetic protein 4 in inner ear development
    • Thompson DL, Gerlach-Bank LM, Barald KF, Koenig RJ. 2003. Retinoic acid repression of bone morphogenetic protein 4 in inner ear development. Mol Cell Biol 23: 2277-2286.
    • (2003) Mol Cell Biol , vol.23 , pp. 2277-2286
    • Thompson, D.L.1    Gerlach-Bank, L.M.2    Barald, K.F.3    Koenig, R.J.4
  • 71
    • 1542328215 scopus 로고    scopus 로고
    • [Histologic and ultrastructural features of cell death both physiological and induced by two different teratogens in branchial arches of mouse embryo]
    • Vanmuylder N, Evrard L, Glineur R, Salmon I, Gashegu J, Rooze M, Louryan S. 2004. [Histologic and ultrastructural features of cell death both physiological and induced by two different teratogens in branchial arches of mouse embryo]. Rev Med Brux 25: 14-20.
    • (2004) Rev Med Brux , vol.25 , pp. 14-20
    • Vanmuylder, N.1    Evrard, L.2    Glineur, R.3    Salmon, I.4    Gashegu, J.5    Rooze, M.6    Louryan, S.7
  • 72
    • 70349186848 scopus 로고    scopus 로고
    • Smad2/3 is involved in growth inhibition of mouse embryonic palate mesenchymal cells induced by all-trans retinoic acid
    • Wang M, Huang H, Chen Y. 2009. Smad2/3 is involved in growth inhibition of mouse embryonic palate mesenchymal cells induced by all-trans retinoic acid. Birth Defects Res A Clin Mol Teratol 85: 780-790.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 780-790
    • Wang, M.1    Huang, H.2    Chen, Y.3
  • 73
    • 0033571603 scopus 로고    scopus 로고
    • Retinoic acid affects left-right patterning
    • Wasiak S, Lohnes D. 1999. Retinoic acid affects left-right patterning. Dev Biol 215: 332-342.
    • (1999) Dev Biol , vol.215 , pp. 332-342
    • Wasiak, S.1    Lohnes, D.2
  • 74
    • 37249079634 scopus 로고    scopus 로고
    • Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo
    • White RJ, Nie Q, Lander AD, Schilling TF. 2007. Complex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo. PLoS Biol 5: e304.
    • (2007) PLoS Biol , vol.5
    • White, R.J.1    Nie, Q.2    Lander, A.D.3    Schilling, T.F.4
  • 75
    • 0028100538 scopus 로고
    • Exposure to retinoic acid before or after the onset of somitogenesis reveals separate effects on rhombomeric segmentation and 3' HoxB gene expression domains
    • Wood H, Pall G, Morriss-Kay G. 1994. Exposure to retinoic acid before or after the onset of somitogenesis reveals separate effects on rhombomeric segmentation and 3' HoxB gene expression domains. Development 120: 2279-2285.
    • (1994) Development , vol.120 , pp. 2279-2285
    • Wood, H.1    Pall, G.2    Morriss-Kay, G.3
  • 76
    • 0042831024 scopus 로고    scopus 로고
    • Fgf3 and Fgf10 are required for mouse otic placode induction
    • Wright TJ, Mansour SL. 2003. Fgf3 and Fgf10 are required for mouse otic placode induction. Development 130: 3379-3390.
    • (2003) Development , vol.130 , pp. 3379-3390
    • Wright, T.J.1    Mansour, S.L.2
  • 77
    • 0031974843 scopus 로고    scopus 로고
    • Axial specification for sensory organs versus non-sensory structures of the chicken inner ear
    • Wu DK, Nunes FD, Choo D. 1998. Axial specification for sensory organs versus non-sensory structures of the chicken inner ear. Development 125: 11-20.
    • (1998) Development , vol.125 , pp. 11-20
    • Wu, D.K.1    Nunes, F.D.2    Choo, D.3


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