A nanobiohybrid complex of recombinant baculovirus and Tat/DNA nanoparticles for delivery of Ang-1 transgene in myocardial infarction therapy

Biomaterials

Volumn 32, Issue 32, 2011, Pages 8304-8318

  Paul, Arghya ^a   Binsalamah, Zyad M ^b   Khan, Afshan A ^c   Abbasia, Sana ^a   Elias, Cynthia B ^c   Shum Tim, Dominique ^b   Prakash, Satya ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^c Sanofi Pasteur   (Canada)

Author keywords

Baculovirus; Encapsulation; Gene therapy; Microencapsulation; Myocardial angiogenesis; Nanoparticle

Indexed keywords

ACUTE MYOCARDIAL INFARCTION; ANGIOGENESIS; BACULOVIRUS; BINARY COMPLEXES; CAPILLARY DENSITY; CARDIOMYOCYTES; CONTROL GROUPS; FUNCTIONAL ASSAYS; GENE DELIVERY; GENE DELIVERY SYSTEMS; IMMUNOGENICITY; IN-VIVO ANALYSIS; INFARCT SIZE; MICROENCAPSULATION; MYOCARDIAL INFARCTION; NANO-DELIVERY SYSTEMS; NONVIRAL; POSITIVELY CHARGED; RAT MODEL; RECOMBINANT BACULOVIRUS; SCALE-UP; SELF-ASSEMBLED; SYNERGISTIC EFFECT; TAT PEPTIDE; THERAPEUTIC APPLICATION; TRANSDUCTION EFFICIENCY; TRANSGENE; VECTOR COMPONENTS;

AMINO ACIDS; BACTERIOPHAGES; ECHOCARDIOGRAPHY; ENCAPSULATION; GENE TRANSFER; NANOPARTICLES;

GENE THERAPY;

ANGIOPOIETIN 1; BETA GALACTOSIDASE; DNA; NANOPARTICLE; VIRUS DNA; VIRUS VECTOR;

ACUTE HEART INFARCTION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOLE; ARTICLE; BACULOVIRUS; CAPILLARY DENSITY; COMPARATIVE STUDY; CONTROLLED STUDY; ECHOCARDIOGRAPHY; EMBRYO; FEMALE; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSDUCTION; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; MOLECULAR HYBRIDIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TRANSGENE; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ANGIOPOIETIN-1; ANIMALS; BACULOVIRIDAE; CHEMOTAXIS; DISEASE MODELS, ANIMAL; DNA; GENE PRODUCTS, TAT; GENE THERAPY; HEART FUNCTION TESTS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MITOSIS; MYOCARDIAL INFARCTION; MYOCARDIUM; NANOPARTICLES; NEOVASCULARIZATION, PHYSIOLOGIC; ORGANOGENESIS; RATS; RECOMBINATION, GENETIC; TRANSDUCTION, GENETIC; TRANSGENES;

RATTUS;

EID: 80052369921     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.07.042     Document Type: Article

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