메뉴 건너뛰기




Volumn 304, Issue 2, 2013, Pages

Improved glycemic control in mice lacking Sglt1 and Sglt2

Author keywords

Diabetes; GLP 1; Knockout; SGLT1; SGLT2

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; GLUCOSE; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 84872407235     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00439.2012     Document Type: Article
Times cited : (138)

References (58)
  • 1
    • 0035122471 scopus 로고    scopus 로고
    • Improved diabetic syndrome in C57BL/KsJdb/db mice by oral administration of the Na(+)-glucose cotransporter inhibitor T-1095
    • Arakawa K, Ishihara T, Oku A, Nawano M, Ueta K, Kitamura K, Matsumoto M, Saito A. Improved diabetic syndrome in C57BL/KsJdb/db mice by oral administration of the Na(+)-glucose cotransporter inhibitor T-1095. Br J Pharmacol 132: 578-586, 2001.
    • (2001) Br J Pharmacol , vol.132 , pp. 578-586
    • Arakawa, K.1    Ishihara, T.2    Oku, A.3    Nawano, M.4    Ueta, K.5    Kitamura, K.6    Matsumoto, M.7    Saito, A.8
  • 6
    • 77954242599 scopus 로고    scopus 로고
    • SGLT2 inhibition-a novel strategy for diabetes treatment
    • Chao EC, Henry RR. SGLT2 inhibition-a novel strategy for diabetes treatment. Nat Rev Drug Discov 9: 551-559, 2010.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 551-559
    • Chao, E.C.1    Henry, R.R.2
  • 7
    • 79952721660 scopus 로고    scopus 로고
    • Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members
    • Chen J, Williams S, Ho S, Loraine H, Hagan D, Whaley JM, Feder JN. Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members. Diabetes Ther 1: 57-92, 2010.
    • (2010) Diabetes Ther , vol.1 , pp. 57-92
    • Chen, J.1    Williams, S.2    Ho, S.3    Loraine, H.4    Hagan, D.5    Whaley, J.M.6    Feder, J.N.7
  • 8
    • 84860252876 scopus 로고    scopus 로고
    • Canagliflozin improves glycemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin
    • Devineni D, Morrow L, Hompesch M, Skee D, Vandebosch A, Murphy J, Ways K, Schwartz S. Canagliflozin improves glycemic control over 28 days in subjects with type 2 diabetes not optimally controlled on insulin. Diabetes Obes Metab 14: 539-545, 2012.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 539-545
    • Devineni, D.1    Morrow, L.2    Hompesch, M.3    Skee, D.4    Vandebosch, A.5    Murphy, J.6    Ways, K.7    Schwartz, S.8
  • 10
    • 0014710867 scopus 로고
    • Free flow micropuncture studies of glucose transport in the rat nephron
    • Frohnert PP, Höhmann B, Zwiebel R, Baumann K. Free flow micropuncture studies of glucose transport in the rat nephron. Pflügers Arch 315: 66-85, 1970.
    • (1970) Pflügers Arch , vol.315 , pp. 66-85
    • Frohnert, P.P.1    Höhmann, B.2    Zwiebel, R.3    Baumann, K.4
  • 11
    • 52649083832 scopus 로고    scopus 로고
    • Remogliflozin etabonate, in a novel category of selective lowaffinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models
    • Fujimori Y, Katsuno K, Nakashima I, Ishikawa-Takemura Y, Fujikura H, Isaji M. Remogliflozin etabonate, in a novel category of selective lowaffinity sodium glucose cotransporter (SGLT2) inhibitors, exhibits antidiabetic efficacy in rodent models. J Pharmacol Exp Ther 327: 268-276, 2008.
    • (2008) J Pharmacol Exp Ther , vol.327 , pp. 268-276
    • Fujimori, Y.1    Katsuno, K.2    Nakashima, I.3    Ishikawa-Takemura, Y.4    Fujikura, H.5    Isaji, M.6
  • 12
    • 64549093267 scopus 로고    scopus 로고
    • Sergliflozin etabonate, a selective SGLT2 inhibitor, improves glycemic control in streptozotocin-induced diabetic rats and Zucker fatty rats
    • Fujimori Y, Katsuno K, Ojima K, Nakashima I, Nakano S, Ishikawa-Takemura Y, Kusama H, Isaji M. Sergliflozin etabonate, a selective SGLT2 inhibitor, improves glycemic control in streptozotocin-induced diabetic rats and Zucker fatty rats. Eur J Pharmacol 609: 148-154, 2009.
    • (2009) Eur J Pharmacol , vol.609 , pp. 148-154
    • Fujimori, Y.1    Katsuno, K.2    Ojima, K.3    Nakashima, I.4    Nakano, S.5    Ishikawa-Takemura, Y.6    Kusama, H.7    Isaji, M.8
  • 16
    • 0018652484 scopus 로고
    • Biochemistry of intestinal development
    • Henning SJ. Biochemistry of intestinal development. Environ Health Perspect 33: 9-16, 1979.
    • (1979) Environ Health Perspect , vol.33 , pp. 9-16
    • Henning, S.J.1
  • 20
    • 0028044629 scopus 로고
    • +/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose
    • +/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose. J Clin Invest 93: 397-404, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 397-404
    • Kanai, Y.1    Lee, W.S.2    You, G.3    Brown, D.4    Hediger, M.A.5
  • 21
    • 68949186346 scopus 로고    scopus 로고
    • Long-term treatment with sergliflozin etabonate improves disturbed glucose metabolism in KK-A(y) mice
    • Katsuno K, Fujimori Y, Ishikawa-Takemura Y, Isaji M. Long-term treatment with sergliflozin etabonate improves disturbed glucose metabolism in KK-A(y) mice. Eur J Pharmacol 618: 98-104, 2009.
    • (2009) Eur J Pharmacol , vol.618 , pp. 98-104
    • Katsuno, K.1    Fujimori, Y.2    Ishikawa-Takemura, Y.3    Isaji, M.4
  • 22
    • 67349275999 scopus 로고    scopus 로고
    • Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus
    • Komoroski B, Vachharajani N, Feng Y, Li L, Kornhauser D, Pfister M. Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther 85: 513-519, 2009.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 513-519
    • Komoroski, B.1    Vachharajani, N.2    Feng, Y.3    Li, L.4    Kornhauser, D.5    Pfister, M.6
  • 24
    • 65349196064 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care 32: 650-657, 2009.
    • (2009) Diabetes Care , vol.32 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3    Tang, W.4    Fiedorek, F.T.5
  • 25
    • 84867142771 scopus 로고    scopus 로고
    • Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin
    • Ljunggren O, Bolinder J, Johansson L, Wilding J, Langkilde AM, Sjöström CD, Sugg J, Parikh S. Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin. Diabetes Obes Metab 14: 990-999, 2012.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 990-999
    • Ljunggren, O.1    Bolinder, J.2    Johansson, L.3    Wilding, J.4    Langkilde, A.M.5    Sjöström, C.D.6    Sugg, J.7    Parikh, S.8
  • 28
    • 0030070055 scopus 로고    scopus 로고
    • +/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption
    • +/glucose cotransporter (SGLT1) trafficking and function cause glucose-galactose malabsorption. Nat Genet 12: 216-220, 1996.
    • (1996) Nat Genet , vol.12 , pp. 216-220
    • Martín, M.G.1    Turk, E.2    Lostao, M.P.3    Kerner, C.4    Wright, E.M.5
  • 29
    • 0021123648 scopus 로고
    • Segmental analysis of renal glucose transport in young female rats
    • McSherry NR, Wen SF. Segmental analysis of renal glucose transport in young female rats. J Physiol 356: 9-19, 1984.
    • (1984) J Physiol , vol.356 , pp. 9-19
    • McSherry, N.R.1    Wen, S.F.2
  • 30
    • 0035857020 scopus 로고    scopus 로고
    • New drug targets for type 2 diabetes and the metabolic syndrome
    • Moller DE. New drug targets for type 2 diabetes and the metabolic syndrome. Nature 414: 821-827, 2001.
    • (2001) Nature , vol.414 , pp. 821-827
    • Moller, D.E.1
  • 31
    • 72249113386 scopus 로고    scopus 로고
    • Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice
    • Moriya R, Shirakura T, Ito J, Mashiko S, Seo T. Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice. Am J Physiol Endocrinol Metab 297: E1358-E1365, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Moriya, R.1    Shirakura, T.2    Ito, J.3    Mashiko, S.4    Seo, T.5
  • 32
    • 84856006973 scopus 로고    scopus 로고
    • A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-transport (SGLT) inhibitors. Systematic review and meta-analysis of randomized trials
    • Musso G, Gambino R, Cassader M, Pagano G. A novel approach to control hyperglycemia in type 2 diabetes: Sodium glucose co-transport (SGLT) inhibitors. Systematic review and meta-analysis of randomized trials. Ann Med Early Online: 1-19, 2011.
    • (2011) Ann Med Early Online , pp. 1-19
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 33
    • 0023130568 scopus 로고
    • Complete absence of tubular glucose reabsorption: A new type of renal glucosuria (type 0)
    • Oemar BS, Byrd DJ, Brodehl J. Complete absence of tubular glucose reabsorption: a new type of renal glucosuria (type 0). Clin Nephrol 27: 156-160, 1987.
    • (1987) Clin Nephrol , vol.27 , pp. 156-160
    • Oemar, B.S.1    Byrd, D.J.2    Brodehl, J.3
  • 39
    • 0023275573 scopus 로고
    • Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats
    • Rossetti L, Smith D, Shulman GI, Papachristou D, DeFronzo RA. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest 79: 1510-1515, 1987.
    • (1987) J Clin Invest , vol.79 , pp. 1510-1515
    • Rossetti, L.1    Smith, D.2    Shulman, G.I.3    Papachristou, D.4    Defronzo, R.A.5
  • 41
    • 77951063464 scopus 로고    scopus 로고
    • Simple pharmacometric tools for oral anti-diabetic drug development: Competitive landscape for oral non-insulin therapies in type 2 diabetes
    • Samtani MN. Simple pharmacometric tools for oral anti-diabetic drug development: competitive landscape for oral non-insulin therapies in type 2 diabetes. Biopharm Drug Dispos 31: 162-177, 2010.
    • (2010) Biopharm Drug Dispos , vol.31 , pp. 162-177
    • Samtani, M.N.1
  • 43
    • 4544284779 scopus 로고    scopus 로고
    • Long-term outcome of renal glucosuria type 0: The original patient and his natural history
    • Scholl-Burgi S, Santer R, Ehrich JHH. Long-term outcome of renal glucosuria type 0: the original patient and his natural history. Nephrol Dial Transplant 19: 2394-2396, 2004.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 2394-2396
    • Scholl-Burgi, S.1    Santer, R.2    Ehrich, J.H.H.3
  • 46
    • 79952728903 scopus 로고    scopus 로고
    • Dapagliflozin: A sodium glucose cotransporter 2 inhibitor in development for type 2 diabetes
    • Tahrani AA, Barnett AH. Dapagliflozin: a sodium glucose cotransporter 2 inhibitor in development for type 2 diabetes. Diabetes Ther 1: 45-56, 2010.
    • (2010) Diabetes Ther , vol.1 , pp. 45-56
    • Tahrani, A.A.1    Barnett, A.H.2
  • 47
    • 0015107142 scopus 로고
    • Glucose transport by proximal renal tubules
    • Tune BM, Burg MB. Glucose transport by proximal renal tubules. Am J Physiol 221: 580-585, 1971.
    • (1971) Am J Physiol , vol.221 , pp. 580-585
    • Tune, B.M.1    Burg, M.B.2
  • 48
    • 0020445298 scopus 로고
    • Further studies of proximal tubular brush border membrane D-glucose transport heterogeneity
    • Turner RJ, Moran A. Further studies of proximal tubular brush border membrane D-glucose transport heterogeneity. J Membr Biol 70: 37-45, 1982.
    • (1982) J Membr Biol , vol.70 , pp. 37-45
    • Turner, R.J.1    Moran, A.2
  • 49
    • 0000920044 scopus 로고
    • Heterogeneity of sodium-dependent D-glucose transport sites along the proximal tubule: Evidence from vesicle studies
    • Turner RJ, Moran A. Heterogeneity of sodium-dependent D-glucose transport sites along the proximal tubule: evidence from vesicle studies. Am J Physiol Renal Fluid Electrolyte Physiol 242: F406-F414, 1982.
    • (1982) Am J Physiol Renal Fluid Electrolyte Physiol , vol.242
    • Turner, R.J.1    Moran, A.2
  • 50
    • 15544383811 scopus 로고    scopus 로고
    • +-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats
    • +-glucose cotransporter inhibitor T-1095 causes sustained improvement in hyperglycemia and prevents diabetic neuropathy in Goto-Kakizaki Rats. Life Sci 76: 2655-2668, 2005.
    • (2005) Life Sci , vol.76 , pp. 2655-2668
    • Ueta, K.1    Ishihara, T.2    Matsumoto, Y.3    Oku, A.4    Nawano, M.5    Fujita, T.6    Saito, A.7    Arakawa, K.8
  • 52
    • 78651349221 scopus 로고    scopus 로고
    • Biology of human sodium glucose transporters
    • Wright EM, Loo DD, Hirayama BA. Biology of human sodium glucose transporters. Physiol Rev 91: 733-794, 2011.
    • (2011) Physiol Rev , vol.91 , pp. 733-794
    • Wright, E.M.1    Loo, D.D.2    Hirayama, B.A.3
  • 56
    • 0037267313 scopus 로고    scopus 로고
    • Knockouts model the 100 best-selling drugs-will they model the next 100?
    • Zambrowicz BP, Sands AT. Knockouts model the 100 best-selling drugs-will they model the next 100? Nat Rev Drug Discov 2: 38-51, 2003.
    • (2003) Nat Rev Drug Discov , vol.2 , pp. 38-51
    • Zambrowicz, B.P.1    Sands, A.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.