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Volumn 2017, Issue 12, 2011, Pages

Glucagon-like peptide analogues for type 2 diabetes mellitus

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALBIGLUTIDE; DULAGLUTIDE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; HEMOGLOBIN A1C; INSULIN GLARGINE; LIRAGLUTIDE; LIXISENATIDE; METFORMIN; ORAL ANTIDIABETIC AGENT; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; SITAGLIPTIN; SULFONYLUREA DERIVATIVE; TASPOGLUTIDE; ANTIDIABETIC AGENT; DRUG DERIVATIVE; GLUCAGON LIKE PEPTIDE 1; GLYCOSYLATED HEMOGLOBIN;

EID: 80155183665     PISSN: 14651858     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD006423.pub2     Document Type: Review
Times cited : (125)

References (115)
  • 1
    • 70349664297 scopus 로고    scopus 로고
    • Potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes
    • Rosenstock J, Reusch J, Bush M, Yang F, Stewart M. Potential of albiglutide, a long-acting GLP-1 receptor agonist, in type 2 diabetes. Diabetes Care 2009;32(10):1880-6.
    • (2009) Diabetes Care , vol.32 , Issue.10 , pp. 1880-1886
    • Rosenstock, J.1    Reusch, J.2    Bush, M.3    Yang, F.4    Stewart, M.5
  • 2
    • 77955573674 scopus 로고    scopus 로고
    • Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial
    • Bergenstal RM, Wysham C, MacConell L, Malloy J, Walsh B, Yan P, et al. Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial. Lancet Aug 2010;376:431-9.
    • (2010) Lancet , vol.376 , pp. 431-439
    • Bergenstal, R.M.1    Wysham, C.2    MacConell, L.3    Malloy, J.4    Walsh, B.5    Yan, P.6
  • 3
    • 79955661908 scopus 로고    scopus 로고
    • DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes
    • Blevins T, Pullman J, Malloy J, Yan P, Taylor K, Schulteis C, et al. DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism 2011;96(5):1301-10.
    • (2011) The Journal of Clinical Endocrinology and Metabolism , vol.96 , Issue.5 , pp. 1301-1310
    • Blevins, T.1    Pullman, J.2    Malloy, J.3    Yan, P.4    Taylor, K.5    Schulteis, C.6
  • 4
    • 77953859640 scopus 로고    scopus 로고
    • Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial
    • Diamant M, Van GL, Stranks S, Northrup J, Cao D, Taylor K, et al. Once weekly exenatide compared with insulin glargine titrated to target in patients with type 2 diabetes (DURATION-3): an open-label randomised trial. Lancet 2010;375:2234-43.
    • (2010) Lancet , vol.375 , pp. 2234-2243
    • Diamant, M.1    Van, G.L.2    Stranks, S.3    Northrup, J.4    Cao, D.5    Taylor, K.6
  • 5
    • 67649774247 scopus 로고    scopus 로고
    • Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily
    • Best JH, Boye KS, Rubin RR, Cao D, Kim TH, Peyrot M. Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily. Diabetic Medicine 2009;26(7):722-8.
    • (2009) Diabetic Medicine , vol.26 , Issue.7 , pp. 722-728
    • Best, J.H.1    Boye, K.S.2    Rubin, R.R.3    Cao, D.4    Kim, T.H.5    Peyrot, M.6
  • 6
    • 78649344474 scopus 로고    scopus 로고
    • Higher diabetes treatment satisfaction associated with improved glucose control for both exenatide once weekly and twice daily
    • Best JH, Rubin RR, Zhuang D, Velez F, Kim T, Peyrot M. Higher diabetes treatment satisfaction associated with improved glucose control for both exenatide once weekly and twice daily. Diabetes 2008;57:A520.
    • (2008) Diabetes , vol.57 , pp. A520
    • Best, J.H.1    Rubin, R.R.2    Zhuang, D.3    Velez, F.4    Kim, T.5    Peyrot, M.6
  • 7
    • 53249142132 scopus 로고    scopus 로고
    • Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study.[see comment]
    • Drucker DJ, Buse JB, Taylor K, Kendall DM, Trautmann M, Zhuang D, et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study.[see comment]. Lancet 2008;372(9645):1240-50.
    • (2008) Lancet , vol.372 , Issue.9645 , pp. 1240-1250
    • Drucker, D.J.1    Buse, J.B.2    Taylor, K.3    Kendall, D.M.4    Trautmann, M.5    Zhuang, D.6
  • 8
    • 77955887980 scopus 로고    scopus 로고
    • Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial
    • Ratner RE, Rosenstock J, Boka G, DRI6012 Study Investigators. Dose-dependent effects of the once-daily GLP-1 receptor agonist lixisenatide in patients with Type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled trial. Diabetic Medicine 2010;27(9):1024-32.
    • (2010) Diabetic Medicine , vol.27 , Issue.9 , pp. 1024-1032
    • Ratner, R.E.1    Rosenstock, J.2    Boka, G.3
  • 9
    • 77954360414 scopus 로고    scopus 로고
    • Improved glycaemic control with minimal hypoglycaemia and no weight change with the once-daily human glucagon-like peptide-1 analogue liraglutide as add-on to sulphonylurea in Japanese patients with type 2 diabetes
    • Kaku K, Rasmussen MF, Clauson P, Seino Y. Improved glycaemic control with minimal hypoglycaemia and no weight change with the once-daily human glucagon-like peptide-1 analogue liraglutide as add-on to sulphonylurea in Japanese patients with type 2 diabetes. Diabetes Obesity and Metabolism 2010;12:341-7.
    • (2010) Diabetes Obesity and Metabolism , vol.12 , pp. 341-347
    • Kaku, K.1    Rasmussen, M.F.2    Clauson, P.3    Seino, Y.4
  • 10
    • 62449129181 scopus 로고    scopus 로고
    • Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU)
    • Marre M, Shaw J, Brändle M, Bebakar WMW, Kamaruddin NA, Strand J, et al. Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU). Diabetic Medicine 2009;26:268-78.
    • (2009) Diabetic Medicine , vol.26 , pp. 268-278
    • Marre, M.1    Shaw, J.2    Brändle, M.3    Bebakar, W.M.W.4    Kamaruddin, N.A.5    Strand, J.6
  • 11
    • 62449169287 scopus 로고    scopus 로고
    • Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study
    • Nauck M, Frid A, Hermansen K, Shah NS, Tankova T, Mitha IH, et al. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (liraglutide effect and action in diabetes)-2 study. Diabetes Care 2009;32(1):84-90.
    • (2009) Diabetes Care , vol.32 , Issue.1 , pp. 84-90
    • Nauck, M.1    Frid, A.2    Hermansen, K.3    Shah, N.S.4    Tankova, T.5    Mitha, I.H.6
  • 12
    • 67650066860 scopus 로고    scopus 로고
    • Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD)
    • Zinman B, Gerich J, Buse JB, Lewin A, Schwartz S, Raskin P, et al. Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met+TZD). Diabetes Care 2009;32(7):1224-30.
    • (2009) Diabetes Care , vol.32 , Issue.7 , pp. 1224-1230
    • Zinman, B.1    Gerich, J.2    Buse, J.B.3    Lewin, A.4    Schwartz, S.5    Raskin, P.6
  • 13
    • 69949117621 scopus 로고    scopus 로고
    • Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial
    • Russell-Jones D, Vaag A, Schmitz O, Sethi BK, Lalic N, Antic S, et al. Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus (LEAD-5 met+SU): a randomised controlled trial. Diabetologia 2009;52:2046-55.
    • (2009) Diabetologia , vol.52 , pp. 2046-2055
    • Russell-Jones, D.1    Vaag, A.2    Schmitz, O.3    Sethi, B.K.4    Lalic, N.5    Antic, S.6
  • 14
    • 77953633959 scopus 로고    scopus 로고
    • Switching from twice-daily exenatide to once-daily liraglutide improves glycemic control in T2D on oral agents
    • Buse J, Sesti G, Schmidt WE, Montanya E, Chang CT, Xu Y, et al. Switching from twice-daily exenatide to once-daily liraglutide improves glycemic control in T2D on oral agents. American Diabetes Association. 2009:591-P.
    • (2009) American Diabetes Association , pp. 591-595
    • Buse, J.1    Sesti, G.2    Schmidt, W.E.3    Montanya, E.4    Chang, C.T.5    Xu, Y.6
  • 15
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6).[see comment]
    • Buse JB, Rosenstock J, Sesti G, Schmidt WE, Montanya E, Brett JH, et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6).[see comment]. Lancet 2009;374(9683):39-47.
    • (2009) Lancet , vol.374 , Issue.9683 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3    Schmidt, W.E.4    Montanya, E.5    Brett, J.H.6
  • 16
    • 77952309372 scopus 로고    scopus 로고
    • Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial
    • Pratley RE, Nauck M, Bailey T, Montanya E, Cuddihy R, Filetti S, et al. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet 2010;375:1447-56.
    • (2010) Lancet , vol.375 , pp. 1447-1456
    • Pratley, R.E.1    Nauck, M.2    Bailey, T.3    Montanya, E.4    Cuddihy, R.5    Filetti, S.6
  • 17
    • 79953035319 scopus 로고    scopus 로고
    • The effects of LY2189265, a long-acting glucagon-like peptide-1 analog, in a randomized, placebo-controlled, double-blind study of overweight/obese patients with type 2 diabetes: the EGO study
    • Umpierrez GE, Blevins T, Rosenstock J, Cheng C, Anderson JH, Bastyr EJ 3rd, EGO Study Group. The effects of LY2189265, a long-acting glucagon-like peptide-1 analog, in a randomized, placebo-controlled, double-blind study of overweight/obese patients with type 2 diabetes: the EGO study. Diabetes, Obesity and Metabolism Jan 2011;13:418-25.
    • (2011) Diabetes, Obesity and Metabolism , vol.13 , pp. 418-425
    • Umpierrez, G.E.1    Blevins, T.2    Rosenstock, J.3    Cheng, C.4    Anderson, J.H.5    Bastyr, E.J.6
  • 18
    • 78649709557 scopus 로고    scopus 로고
    • Liraglutide provides similar glycaemic control as glimepiride (both in combination with metformin) and reduces body weight and systolic blood pressure in Asian population with type 2 diabetes from China, South Korea and India: a 16-week, randomized, double-blind, active control trial
    • Yang W, Chen L, Ji Q, Liu X, Ma J, Tandon N, et al. Liraglutide provides similar glycaemic control as glimepiride (both in combination with metformin) and reduces body weight and systolic blood pressure in Asian population with type 2 diabetes from China, South Korea and India: a 16-week, randomized, double-blind, active control trial. Diabetes, Obesity and Metabolism Jan 2011;13(1):81-88.
    • (2011) Diabetes, Obesity and Metabolism , vol.13 , Issue.1 , pp. 81-88
    • Yang, W.1    Chen, L.2    Ji, Q.3    Liu, X.4    Ma, J.5    Tandon, N.6
  • 19
    • 67649523294 scopus 로고    scopus 로고
    • Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combination with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: a double-blind placebo-controlled study
    • Nauck MA, Ratner RE, Kapitza C, Berria R, Boldrin M, Balena R. Treatment with the human once-weekly glucagon-like peptide-1 analog taspoglutide in combination with metformin improves glycemic control and lowers body weight in patients with type 2 diabetes inadequately controlled with metformin alone: a double-blind placebo-controlled study. Diabetes Care 2009;32(7):1237-43.
    • (2009) Diabetes Care , vol.32 , Issue.7 , pp. 1237-1243
    • Nauck, M.A.1    Ratner, R.E.2    Kapitza, C.3    Berria, R.4    Boldrin, M.5    Balena, R.6
  • 20
    • 77951277026 scopus 로고    scopus 로고
    • Safety and tolerability of high doses of taspoglutide, a once-weekly human GLP-1 analogue, in diabetic patients treated with metformin: a randomized double-blind placebo-controlled study
    • Ratner R, Nauck M, Kapitza C, Asnaghi V, Boldrin M, Balena R. Safety and tolerability of high doses of taspoglutide, a once-weekly human GLP-1 analogue, in diabetic patients treated with metformin: a randomized double-blind placebo-controlled study. Diabetic Medicine 2010;27:556-62.
    • (2010) Diabetic Medicine , vol.27 , pp. 556-562
    • Ratner, R.1    Nauck, M.2    Kapitza, C.3    Asnaghi, V.4    Boldrin, M.5    Balena, R.6
  • 21
    • 70350619609 scopus 로고    scopus 로고
    • Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
    • 2009 Nov 7
    • Astrup A, Rossner S, Van Gaal L, Rissanen A, Niskanen L, Al Hakim M, et al. NN8022-1807 Study Group. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet 2009 Nov 7;374:1606-16.
    • Lancet , vol.374 , pp. 1606-1616
    • Astrup, A.1    Rossner, S.2    Van Gaal, L.3    Rissanen, A.4    Niskanen, L.5    Al Hakim, M.6
  • 22
    • 37349008890 scopus 로고    scopus 로고
    • Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial
    • Barnett AH, Burger J, Johns D, Brodows R, Kendall DM, Roberts A, et al. Tolerability and efficacy of exenatide and titrated insulin glargine in adult patients with type 2 diabetes previously uncontrolled with metformin or a sulfonylurea: a multinational, randomized, open-label, two-period, crossover noninferiority trial. Clinical Therapeutics 2007;29:2333-48.
    • (2007) Clinical Therapeutics , vol.29 , pp. 2333-2348
    • Barnett, A.H.1    Burger, J.2    Johns, D.3    Brodows, R.4    Kendall, D.M.5    Roberts, A.6
  • 23
    • 85036524817 scopus 로고    scopus 로고
    • Improved treatment satisfaction in patients with type-2 diabetes treated with exenatide or insulin glargine
    • Secnik K, Hayes C, Matza L, Kim S, Oglesby A, Yurgin N, et al. Improved treatment satisfaction in patients with type-2 diabetes treated with exenatide or insulin glargine. Value in Health 2005;8:A155-A156.
    • (2005) Value in Health , vol.8 , pp. A155-A156
    • Secnik, K.1    Hayes, C.2    Matza, L.3    Kim, S.4    Oglesby, A.5    Yurgin, N.6
  • 24
    • 48749109684 scopus 로고    scopus 로고
    • Less hypoglycemia with exenatide versus insulin glargine, despite similar Hba(1c) improvement, in patients with T2dm adjunctively treated with metformin
    • Trautmann M, Burger J, Johns D, Brodows R, Okerson T, Roberts A, et al. Less hypoglycemia with exenatide versus insulin glargine, despite similar Hba(1c) improvement, in patients with T2dm adjunctively treated with metformin. Diabetes 2007;56:A45.
    • (2007) Diabetes , vol.56 , pp. A45
    • Trautmann, M.1    Burger, J.2    Johns, D.3    Brodows, R.4    Okerson, T.5    Roberts, A.6
  • 25
    • 85036546964 scopus 로고    scopus 로고
    • Relationship between hypoglycaemia, background oral antidiabetic agent, and glycaemic control in patients treated with exenatide or insulin glargine
    • Trautmann M, Burger J, Johns D, Brodows R, Okerson T, Roberts A, et al. Relationship between hypoglycaemia, background oral antidiabetic agent, and glycaemic control in patients treated with exenatide or insulin glargine. Diabetologia 2007;50:S338.
    • (2007) Diabetologia , vol.50 , pp. S338
    • Trautmann, M.1    Burger, J.2    Johns, D.3    Brodows, R.4    Okerson, T.5    Roberts, A.6
  • 26
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C,weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes
    • Blonde L, Klein EJ, Han J, Zhang B, Mac SM, Poon TH, et al. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82 weeks in 314 overweight patients with type 2 diabetes. Diabetes, Obesity and Metabolism 2006;8:436-47.
    • (2006) Diabetes, Obesity and Metabolism , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3    Zhang, B.4    Mac, S.M.5    Poon, T.H.6
  • 27
    • 77954184211 scopus 로고    scopus 로고
    • Patient-reported outcomes following treatment with the human GLP-1 analogue liraglutide or glimepiride in monotherapy: results from a randomized controlled trial in patients with type 2 diabetes
    • Bode BW, Testa MA, Magwire M, Hale PM, Hammer M, Blonde L, et al. LEAD-3 Study Group. Patient-reported outcomes following treatment with the human GLP-1 analogue liraglutide or glimepiride in monotherapy: results from a randomized controlled trial in patients with type 2 diabetes. Diabetes Obesity and Metabolism 2010 Jul;12(7):604-12.
    • (2010) Diabetes Obesity and Metabolism , vol.12 , Issue.7 , pp. 604-612
    • Bode, B.W.1    Testa, M.A.2    Magwire, M.3    Hale, P.M.4    Hammer, M.5    Blonde, L.6
  • 28
    • 70450203583 scopus 로고    scopus 로고
    • Six-month outcomes on A1C and cardiovascular risk factors in patients with type 2 diabetes treated with exenatide in an ambulatory care setting
    • Brixner DI, McAdam-Marx C, Ye X, Boye KS, Nielsen LL, Wintle M, et al. Six-month outcomes on A1C and cardiovascular risk factors in patients with type 2 diabetes treated with exenatide in an ambulatory care setting. Diabetes Obesity and Metabolism 2009 Dec;11(12):1122-30.
    • (2009) Diabetes Obesity and Metabolism , vol.11 , Issue.12 , pp. 1122-1130
    • Brixner, D.I.1    McAdam-Marx, C.2    Ye, X.3    Boye, K.S.4    Nielsen, L.L.5    Wintle, M.6
  • 29
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • Buse JB, Henry RR, Han J, Kim DD, Fineman MS, Baron AD. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 2004;27(11):2628-35.
    • (2004) Diabetes Care , vol.27 , Issue.11 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3    Kim, D.D.4    Fineman, M.S.5    Baron, A.D.6
  • 30
    • 22644444292 scopus 로고    scopus 로고
    • Effects of liraglutide (NN2211), a long-acting GLP-1analogue, on glycaemic control and bodyweight in subjects with type 2 diabetes
    • Feinglos MN, Saad MF, Pi-Sunyer FX, An B, Santiago O, Liraglutide Dose-Response Study Group. Effects of liraglutide (NN2211), a long-acting GLP-1analogue, on glycaemic control and bodyweight in subjects with type 2 diabetes. Diabetic Medicine 2005;22:1016-23.
    • (2005) Diabetic Medicine , vol.22 , pp. 1016-1023
    • Feinglos, M.N.1    Saad, M.F.2    Pi-Sunyer, F.X.3    An, B.4    Santiago, O.5
  • 31
    • 72449154207 scopus 로고    scopus 로고
    • Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time
    • Gallwitz B, Vaag A, Falahati A, Madsbad S. Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time. International Journal of Clinical Practice 2010 Jan;64(2):267-76.
    • (2010) International Journal of Clinical Practice , vol.64 , Issue.2 , pp. 267-276
    • Gallwitz, B.1    Vaag, A.2    Falahati, A.3    Madsbad, S.4
  • 32
    • 59449101432 scopus 로고    scopus 로고
    • Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial.[see comment]
    • Garber A, Henry R, Ratner R, Garcia-Hernandez PA, Rodriguez-Pattzi H, Olvera-Alvarez I, et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial.[see comment]. Lancet 2009;373(9662):473-81.
    • (2009) Lancet , vol.373 , Issue.9662 , pp. 473-481
    • Garber, A.1    Henry, R.2    Ratner, R.3    Garcia-Hernandez, P.A.4    Rodriguez-Pattzi, H.5    Olvera-Alvarez, I.6
  • 33
    • 70350764845 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic properties of taspoglutide, a once-weekly, human GLP-1 analogue, after single-dose administration in patients with Type 2 diabetes
    • Kapitza C, Heise T, Birman P, Jallet K, Ramis J, Balena R. Pharmacokinetic and pharmacodynamic properties of taspoglutide, a once-weekly, human GLP-1 analogue, after single-dose administration in patients with Type 2 diabetes. Diabetic Medicine 2009 Nov;26(11):1156-64.
    • (2009) Diabetic Medicine , vol.26 , Issue.11 , pp. 1156-1164
    • Kapitza, C.1    Heise, T.2    Birman, P.3    Jallet, K.4    Ramis, J.5    Balena, R.6
  • 34
    • 34249891874 scopus 로고    scopus 로고
    • Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes
    • Kim D, MacConell L, Zhuang D, Kothare PA, Trautmann M, Fineman M, et al. Effects of once-weekly dosing of a long-acting release formulation of exenatide on glucose control and body weight in subjects with type 2 diabetes. Diabetes Care 2007;30:1487-93.
    • (2007) Diabetes Care , vol.30 , pp. 1487-1493
    • Kim, D.1    MacConell, L.2    Zhuang, D.3    Kothare, P.A.4    Trautmann, M.5    Fineman, M.6
  • 35
    • 2542451393 scopus 로고    scopus 로고
    • Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211)
    • Madsbad S, Schmitz O, Ranstam J, Jakobsen G, Matthews DR, NN2211-1310 International study group. Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211). Diabetes Care 2004;27:1335-42.
    • (2004) Diabetes Care , vol.27 , pp. 1335-1342
    • Madsbad, S.1    Schmitz, O.2    Ranstam, J.3    Jakobsen, G.4    Matthews, D.R.5
  • 36
    • 65549096266 scopus 로고    scopus 로고
    • Pharmacology and tolerability of a single dose of exenatide in adolescent patients with type 2 diabetes mellitus being treated with metformin: a randomized, placebo-controlled, single-blind, dose-escalation, crossover study
    • Malloy J, Capparelli E, Gottschalk M, Guan X, Kothare P, Fineman M. Pharmacology and tolerability of a single dose of exenatide in adolescent patients with type 2 diabetes mellitus being treated with metformin: a randomized, placebo-controlled, single-blind, dose-escalation, crossover study. Clinical Therapeutics 2009 Apr;31(4):806-15.
    • (2009) Clinical Therapeutics , vol.31 , Issue.4 , pp. 806-815
    • Malloy, J.1    Capparelli, E.2    Gottschalk, M.3    Guan, X.4    Kothare, P.5    Fineman, M.6
  • 37
    • 51549095571 scopus 로고    scopus 로고
    • Efficacy and tolerability of exenatide monotherapy over 24 weeks in antidiabetic drug-naive patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel-group study
    • Moretto TJ, Milton DR, Ridge TD, Macconell LA, Okerson T, Wolka AM, et al. Efficacy and tolerability of exenatide monotherapy over 24 weeks in antidiabetic drug-naive patients with type 2 diabetes: a randomized, double-blind, placebo-controlled, parallel-group study. Clinical Therapeutics 2008;30:1448-60.
    • (2008) Clinical Therapeutics , vol.30 , pp. 1448-1460
    • Moretto, T.J.1    Milton, D.R.2    Ridge, T.D.3    Macconell, L.A.4    Okerson, T.5    Wolka, A.M.6
  • 38
    • 3342984674 scopus 로고    scopus 로고
    • The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes
    • Harder H, Nielsen L, Thi TDT, Astrup A. The effect of liraglutide, a long-acting glucagon-like peptide 1 derivative, on glycemic control, body composition, and 24-h energy expenditure in patients with type 2 diabetes. Diabetes Care 2004;27:1915-21.
    • (2004) Diabetes Care , vol.27 , pp. 1915-1921
    • Harder, H.1    Nielsen, L.2    Thi, T.D.T.3    Astrup, A.4
  • 39
    • 67549125152 scopus 로고    scopus 로고
    • Adding liraglutide to oral antidiabetic drug monotherapy: efficacy and weight benefits
    • Nauck M, Marre M. Adding liraglutide to oral antidiabetic drug monotherapy: efficacy and weight benefits. Postgraduate Medicine 2009;121(3):5-15.
    • (2009) Postgraduate Medicine , vol.121 , Issue.3 , pp. 5-15
    • Nauck, M.1    Marre, M.2
  • 40
    • 76749161358 scopus 로고    scopus 로고
    • Effects of exenatide on systolic blood pressure in subjects with type 2 diabetes
    • Okerson T, Yan P, Stonehouse A, Brodows R. Effects of exenatide on systolic blood pressure in subjects with type 2 diabetes. American Journal of Hypertension 2010 Mar;23(3):334-39.
    • (2010) American Journal of Hypertension , vol.23 , Issue.3 , pp. 334-339
    • Okerson, T.1    Yan, P.2    Stonehouse, A.3    Brodows, R.4
  • 41
    • 33749364478 scopus 로고    scopus 로고
    • Exenatide elicits sustained glycaemic control and progressive reduction of body weight in patients with type 2 diabetes inadequately controlled by sulphonylureas with or without metformin
    • Riddle MC, Henry RR, Poon TH, Zhang B, Mac MS, John HH, et al. Exenatide elicits sustained glycaemic control and progressive reduction of body weight in patients with type 2 diabetes inadequately controlled by sulphonylureas with or without metformin. Diabetes/Metabolism Research and Reviews 2006;22:483-91.
    • (2006) Diabetes/Metabolism Research and Reviews , vol.22 , pp. 483-491
    • Riddle, M.C.1    Henry, R.R.2    Poon, T.H.3    Zhang, B.4    Mac, M.S.5    John, H.H.6
  • 42
    • 47649094517 scopus 로고    scopus 로고
    • Dose-dependent improvement in glycemia with once-daily liraglutide without hypoglycemia or weight gain: A double-blind, randomized, controlled trial in Japanese patients with type 2 diabetes
    • Seino Y, Rasmussen MF, Zdravkovic M, Kaku K. Dose-dependent improvement in glycemia with once-daily liraglutide without hypoglycemia or weight gain: A double-blind, randomized, controlled trial in Japanese patients with type 2 diabetes. Diabetes Research and Clinical Practice 2008;81(2):161-8.
    • (2008) Diabetes Research and Clinical Practice , vol.81 , Issue.2 , pp. 161-168
    • Seino, Y.1    Rasmussen, M.F.2    Zdravkovic, M.3    Kaku, K.4
  • 44
    • 50649110233 scopus 로고    scopus 로고
    • Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with type 2 diabetes
    • Courreges JP, Vilsboll T, Zdravkovic M, Le-Thi T, Krarup T, Schmitz O, et al. Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with type 2 diabetes. Diabetic Medicine 2008;25(9):1129-31.
    • (2008) Diabetic Medicine , vol.25 , Issue.9 , pp. 1129-1131
    • Courreges, J.P.1    Vilsboll, T.2    Zdravkovic, M.3    Le-Thi, T.4    Krarup, T.5    Schmitz, O.6
  • 45
    • 45449114603 scopus 로고    scopus 로고
    • Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide
    • Horowitz M. Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide. Diabetes, Obesity and Metabolism 2008;10:593-02.
    • (2008) Diabetes, Obesity and Metabolism , vol.10 , pp. 502-593
    • Horowitz, M.1
  • 46
    • 85036556741 scopus 로고    scopus 로고
    • Projecting the long-term clinical benefits of treatment with the GLP-1 analogue liraglutide in subjects with type 2 diabetes
    • Valentine WJ, Hammer M, Palmer AJ, Ray JA. Projecting the long-term clinical benefits of treatment with the GLP-1 analogue liraglutide in subjects with type 2 diabetes. Diabetes 2007;56:A568.
    • (2007) Diabetes , vol.56 , pp. A568
    • Valentine, W.J.1    Hammer, M.2    Palmer, A.J.3    Ray, J.A.4
  • 47
    • 39749143348 scopus 로고    scopus 로고
    • Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with type 2 diabetes mellitus
    • Vilsboll T, Brock B, Perrild H, Levin K, Lervang HH, Kolendorf K, et al. Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with type 2 diabetes mellitus. Diabetic Medicine 2008;25(2):152-56.
    • (2008) Diabetic Medicine , vol.25 , Issue.2 , pp. 152-156
    • Vilsboll, T.1    Brock, B.2    Perrild, H.3    Levin, K.4    Lervang, H.H.5    Kolendorf, K.6
  • 48
    • 34249869806 scopus 로고    scopus 로고
    • Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes
    • Vilsboll T, Zdravkovic M, Le-Thi T, Krarup T, Schmitz O, Courreges JP, et al. Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes. Diabetes Care 2007;30:1608-10.
    • (2007) Diabetes Care , vol.30 , pp. 1608-1610
    • Vilsboll, T.1    Zdravkovic, M.2    Le-Thi, T.3    Krarup, T.4    Schmitz, O.5    Courreges, J.P.6
  • 49
    • 85020487985 scopus 로고    scopus 로고
    • Efficacy and safety of albiglutide in treatment of type 2 diabetes
    • NCT00838903. Efficacy and safety of albiglutide in treatment of type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT00838903.
  • 50
    • 85036552941 scopus 로고    scopus 로고
    • A study to determine the safety and efficacy of albiglutide in patients with type 2 diabetes
    • NCT00838916. A study to determine the safety and efficacy of albiglutide in patients with type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT00838916.
  • 51
    • 85020524000 scopus 로고    scopus 로고
    • Safety and efficacy study of albiglutide in type 2 diabetes
    • NCT00849017. Safety and efficacy study of albiglutide in type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT00849017.
  • 52
    • 85036593623 scopus 로고    scopus 로고
    • Safety and efficacy of albiglutide in type 2 diabetes
    • NCT00849056. Safety and efficacy of albiglutide in type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT00849056.
  • 53
    • 85036591435 scopus 로고    scopus 로고
    • Dose ranging study of albiglutide in Japanese subjects
    • NCT01098461. Dose ranging study of albiglutide in Japanese subjects. http://clinicaltrials.gov/ct2/show/NCT01098461.
  • 54
    • 85036581641 scopus 로고    scopus 로고
    • A study to determine the efficacy and safety of albiglutide as compared with liraglutide.
    • accessed 17 June 2011
    • NCT01128894. A study to determine the efficacy and safety of albiglutide as compared with liraglutide. http://clinicaltrials.gov/ct2/show/NCT01128894 accessed 17 June 2011.
  • 55
    • 85036506285 scopus 로고    scopus 로고
    • Efficacy of exenatide once weekly and once-daily insulin glargine in patients with type 2 diabetes treated with metformin alone or in combination with sulfonylurea (DURATION - 3)
    • NCT00641056. Efficacy of exenatide once weekly and once-daily insulin glargine in patients with type 2 diabetes treated with metformin alone or in combination with sulfonylurea (DURATION - 3). http://clinicaltrials.gov/ct2/show/NCT00641056.
  • 56
    • 85036545061 scopus 로고    scopus 로고
    • A study to examine the effects of exenatide once-weekly injection on glucose control and safety in Asian subjects
    • NCT00917267. A study to examine the effects of exenatide once-weekly injection on glucose control and safety in Asian subjects. http://clinicaltrials.gov/ct2/show/NCT00917267.
  • 57
    • 85036558676 scopus 로고    scopus 로고
    • Study to evaluate the efficacy and safety of exenatide once-weekly injection compared to once-daily insulin in type 2 diabetes mellitus
    • NCT00935532. Study to evaluate the efficacy and safety of exenatide once-weekly injection compared to once-daily insulin in type 2 diabetes mellitus. http://clinicaltrials.gov/ct2/show/NCT00935532.
  • 58
    • 85036562582 scopus 로고    scopus 로고
    • Efficacy of once-weekly exenatide versus once or twice daily insulin detemir in patients with type 2 diabetes
    • NCT01003184. Efficacy of once-weekly exenatide versus once or twice daily insulin detemir in patients with type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT01003184.
  • 59
    • 85036566635 scopus 로고    scopus 로고
    • Safety and efficacy of exenatide once weekly versus liraglutide in subjects with type 2 diabetes
    • accessed 17 June 2011
    • NCT01029886. Safety and efficacy of exenatide once weekly versus liraglutide in subjects with type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT01029886 accessed 17 June 2011.
  • 60
    • 84872326015 scopus 로고    scopus 로고
    • Exenatide study of cardiovascular event lowering trial (EXSCEL): a trial to evaluate cardiovascular outcomes after treatment with exenatide once weekly in patients with type 2 diabetes mellitus
    • NCT01144338. Exenatide study of cardiovascular event lowering trial (EXSCEL): a trial to evaluate cardiovascular outcomes after treatment with exenatide once weekly in patients with type 2 diabetes mellitus. http://clinicaltrials.gov/ct2/show/NCT01144338.
  • 61
    • 84877863308 scopus 로고    scopus 로고
    • The effect of insulin detemir in combination with liraglutide and metformin compared to liraglutide and metformin in subjects with type 2 diabetes
    • accessed 17 June 2011
    • NCT00856986. The effect of insulin detemir in combination with liraglutide and metformin compared to liraglutide and metformin in subjects with type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT00856986 accessed 17 June 2011.
  • 62
    • 85036508176 scopus 로고    scopus 로고
    • Efficacy assessment of insulin glargine versus liraglutide after oral agent failure (EAGLE)
    • accessed 17 June 2011
    • NCT01117350. Efficacy assessment of insulin glargine versus liraglutide after oral agent failure (EAGLE). http://clinicaltrials.gov/ct2/show/NCT01117350 accessed 17 June 2011.
  • 63
    • 85036514857 scopus 로고    scopus 로고
    • Comparison of two treatment regimens (sitagliptin versus liraglutide) on participants who failed to achieve good glucose control on metformin alone (MK-0431-403)
    • accessed 17 June 2011
    • NCT01296412. Comparison of two treatment regimens (sitagliptin versus liraglutide) on participants who failed to achieve good glucose control on metformin alone (MK-0431-403). http://clinicaltrials.gov/ct2/show/NCT01296412 accessed 17 June 2011.
  • 64
    • 85036587896 scopus 로고    scopus 로고
    • Dual action of liraglutide and insulin degludec in type 2 diabetes: a trial comparing the efficacy and safety of insulin degludec/liraglutide, insulin degludec and liraglutide in subjects with type 2 diabetes (DUAL™ I)
    • accessed 17 June 2011
    • NCT01336023. Dual action of liraglutide and insulin degludec in type 2 diabetes: a trial comparing the efficacy and safety of insulin degludec/liraglutide, insulin degludec and liraglutide in subjects with type 2 diabetes (DUAL™ I). http://clinicaltrials.gov/ct2/show/NCT01336023 accessed 17 June 2011.
  • 65
    • 66749139207 scopus 로고    scopus 로고
    • GLP-1 agonist AVE0010 versus exenatide in patients with type 2 diabetes for glycemic control and safety evaluation, on top of metformin (GETGOAL-X)
    • accessed 17 June 2011
    • NCT00707031. GLP-1 agonist AVE0010 versus exenatide in patients with type 2 diabetes for glycemic control and safety evaluation, on top of metformin (GETGOAL-X). http://clinicaltrials.gov/ct2/show/NCT00707031 accessed 17 June 2011.
  • 66
    • 66749139207 scopus 로고    scopus 로고
    • GLP-1 agonist AVE0010 in patients with type 2 diabetes for glycemic control and safety evaluation, on top of sulfonylurea (GETGOAL-S)
    • accessed 17 June 2011
    • NCT00713830. GLP-1 agonist AVE0010 in patients with type 2 diabetes for glycemic control and safety evaluation, on top of sulfonylurea (GETGOAL-S). http://clinicaltrials.gov/ct2/show/NCT00713830 accessed 17 June 2011.
  • 67
    • 66749139207 scopus 로고    scopus 로고
    • GLP-1 agonist AVE0010 in patients with type 2 diabetes for glycemic control and safety evaluation, on top of pioglitazone (GETGOAL-P)
    • accessed 17 June 2011
    • NCT00763815. GLP-1 agonist AVE0010 in patients with type 2 diabetes for glycemic control and safety evaluation, on top of pioglitazone (GETGOAL-P). http://clinicaltrials.gov/ct2/show/NCT00763815 accessed 17 June 2011.
  • 68
    • 84877848456 scopus 로고    scopus 로고
    • 24-week treatment with lixisenatide in type 2 diabetes insufficiently controlled with metformin and insulin glargine
    • accessed 17 June 2011
    • NCT00975286. 24-week treatment with lixisenatide in type 2 diabetes insufficiently controlled with metformin and insulin glargine. http://clinicaltrials.gov/ct2/show/NCT00975286 accessed 17 June 2011.
  • 69
    • 85036499374 scopus 로고    scopus 로고
    • 24-week study comparing lixisenatide to sitagliptin as add-on to metformin in obese type 2 diabetic patients younger than 50
    • accessed 17 June 2011
    • NCT00976937. 24-week study comparing lixisenatide to sitagliptin as add-on to metformin in obese type 2 diabetic patients younger than 50. http://clinicaltrials.gov/ct2/show/NCT00976937 accessed 17 June 2011.
  • 70
    • 85036503458 scopus 로고    scopus 로고
    • A randomised controlled clinical trial in type 2 diabetes comparing semaglutide to placebo and liraglutide
    • accessed 17 June 2011
    • NCT00696657. A randomised controlled clinical trial in type 2 diabetes comparing semaglutide to placebo and liraglutide. http://clinicaltrials.gov/ct2/show/NCT00696657 accessed 17 June 2011.
  • 71
    • 85036552465 scopus 로고    scopus 로고
    • A study of taspoglutide versus exenatide for the treatment of patients with type 2 diabetes mellitus inadequately controlled with metformin, thiazolidinedione or a combination of both
    • accessed 17 June 2011
    • NCT00717457. A study of taspoglutide versus exenatide for the treatment of patients with type 2 diabetes mellitus inadequately controlled with metformin, thiazolidinedione or a combination of both. http://clinicaltrials.gov/ct2/show/NCT00717457 accessed 17 June 2011.
  • 72
    • 66749116810 scopus 로고    scopus 로고
    • A study of taspoglutide versus placebo for the treatment of patients with type 2 diabetes mellitus inadequately controlled with metformin plus pioglitazone
    • accessed 17 June 2011
    • NCT00744367. A study of taspoglutide versus placebo for the treatment of patients with type 2 diabetes mellitus inadequately controlled with metformin plus pioglitazone. http://clinicaltrials.gov/ct2/show/NCT00744367 accessed 17 June 2011.
  • 73
    • 66749116810 scopus 로고    scopus 로고
    • A study of taspoglutide versus sitagliptin for the treatment of patients with type 2 diabetes mellitus inadequately controlled with metformin
    • accessed 17 June 2011
    • NCT00754988. A study of taspoglutide versus sitagliptin for the treatment of patients with type 2 diabetes mellitus inadequately controlled with metformin. http://clinicaltrials.gov/ct2/show/NCT00754988 accessed 17 June 2011.
  • 74
    • 66749087110 scopus 로고    scopus 로고
    • A study of the safety, tolerability and effect on glycemic control of taspoglutide versus insulin glargine in insulin naive type 2 diabetic patients inadequately controlled with metformin plus sulphonylurea
    • accessed 17 June 2011
    • NCT00755287. A study of the safety, tolerability and effect on glycemic control of taspoglutide versus insulin glargine in insulin naive type 2 diabetic patients inadequately controlled with metformin plus sulphonylurea. http://clinicaltrials.gov/ct2/show/NCT00755287 accessed 17 June 2011.
  • 75
    • 85036562558 scopus 로고    scopus 로고
    • A study of taspoglutide versus placebo for the treatment of obese patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy
    • accessed 17 June 2011
    • NCT00823992. A study of taspoglutide versus placebo for the treatment of obese patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy. http://clinicaltrials.gov/ct2/show/NCT00823992 accessed 17 June 2011.
  • 76
    • 85036495218 scopus 로고    scopus 로고
    • A study of taspoglutide versus pioglitazone in patients with type 2 diabetes
    • accessed 17 June 2011
    • NCT00909597. A study of taspoglutide versus pioglitazone in patients with type 2 diabetes. http://clinicaltrials.gov/ct2/show/NCT00909597 accessed 17 June 2011.
  • 77
    • 0036323269 scopus 로고    scopus 로고
    • Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells
    • Abraham EJ, Leech CA, Lin JC, Zulewski H, Habener JF. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology 2002;143(8):3152-61.
    • (2002) Endocrinology , vol.143 , Issue.8 , pp. 3152-3161
    • Abraham, E.J.1    Leech, C.A.2    Lin, J.C.3    Zulewski, H.4    Habener, J.F.5
  • 78
    • 0003172751 scopus 로고    scopus 로고
    • Report on the Expert Committee on the Diagnosis and Classication of Diabetes Mellitus
    • American Diabetes Association. Report on the Expert Committee on the Diagnosis and Classication of Diabetes Mellitus. Diabetes Care 1997;20(Suppl 1):S5-20.
    • (1997) Diabetes Care , vol.20 , pp. S5-20
  • 79
    • 0032952815 scopus 로고    scopus 로고
    • Report of the Expert Committee on the diagnosis and classification of diabetes mellitus
    • The Expert Committee on the Diagnosis and Classication of Diabetes Mellitus. Report of the Expert Committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 1999;22(Suppl 1):S5-19.
    • (1999) Diabetes Care , vol.22 , pp. S5-19
  • 81
    • 4344667831 scopus 로고    scopus 로고
    • A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis
    • Baggio LL, Huang Q, Brown TJ, Drucker DJ. A recombinant human glucagon-like peptide (GLP)-1-albumin protein (albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis. Diabetes 2004;53(9):2492-500.
    • (2004) Diabetes , vol.53 , Issue.9 , pp. 2492-2500
    • Baggio, L.L.1    Huang, Q.2    Brown, T.J.3    Drucker, D.J.4
  • 82
    • 60349099802 scopus 로고    scopus 로고
    • New treatments in type 2 diabetes: a focus on the incretin-based therapies
    • Barnett AH. New treatments in type 2 diabetes: a focus on the incretin-based therapies. Clinical Endocrinology 2009;70:343-53.
    • (2009) Clinical Endocrinology , vol.70 , pp. 343-353
    • Barnett, A.H.1
  • 83
    • 72449148137 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 therapy and the exocrine pancreas: innocent bystander or friendly fire?
    • Butler PC, Matveyenko AV, Dry S, Bhushan A, Elashoff R. Glucagon-like peptide-1 therapy and the exocrine pancreas: innocent bystander or friendly fire?. Diabetologia 2010;53:1-5.
    • (2010) Diabetologia , vol.53 , pp. 1-5
    • Butler, P.C.1    Matveyenko, A.V.2    Dry, S.3    Bhushan, A.4    Elashoff, R.5
  • 85
    • 85036568888 scopus 로고    scopus 로고
    • Assessment report for Victoza (liraglutide)
    • accessed 10 March 2010
    • EMEA. Assessment report for Victoza (liraglutide). http://www.emea.europa.eu/humandocs/PDFs/EPAR/victoza/H-1026-en6.pdf accessed 10 March 2010.
  • 86
    • 0345374580 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets.[see comment]
    • Farilla L, Bulotta A, Hirshberg B, Li CS, Khoury N, Noushmehr H, et al. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets.[see comment]. Endocrinology 2003;144(12):5149-58.
    • (2003) Endocrinology , vol.144 , Issue.12 , pp. 5149-5158
    • Farilla, L.1    Bulotta, A.2    Hirshberg, B.3    Li, C.S.4    Khoury, N.5    Noushmehr, H.6
  • 87
    • 84877598164 scopus 로고    scopus 로고
    • Information for Healthcare Professionals: Exenatide (marketed as Byetta)
    • accessed 10 March 2010
    • FDA. Information for Healthcare Professionals: Exenatide (marketed as Byetta). http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm124713.htm accessed 10 March 2010.
  • 88
    • 77956600662 scopus 로고    scopus 로고
    • Byetta (exenatide) prescribing information
    • accessed 10 March 2010
    • FDA. Byetta (exenatide) prescribing information. http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021773s9s11s18s22s25lbl.pdf accessed 10 March 2010.
  • 89
    • 84860703963 scopus 로고    scopus 로고
    • Information for Healthcare Professionals: Reports of Altered Kidney Function in patients using Exenatide (Marketed as Byetta)
    • accessed 10 March 2010
    • FDA. Information for Healthcare Professionals: Reports of Altered Kidney Function in patients using Exenatide (Marketed as Byetta). http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm188656.htm accessed 10 March 2010.
  • 90
    • 84871354194 scopus 로고    scopus 로고
    • Byetta Safety Update for Healthcare Professionals
    • accessed 10 March 2010
    • FDA. Byetta Safety Update for Healthcare Professionals. http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/DrugSafetyInformationforHeathcareProfessionals/ucm190406.htm accessed 10 March 2010.
  • 94
    • 63849105841 scopus 로고    scopus 로고
    • Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]
    • editors
    • Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org.
    • (2011) The Cochrane Collaboration
    • Higgins, J.P.T.1    Green, S.2
  • 95
    • 85036527155 scopus 로고    scopus 로고
    • FDA Reminds Clinicians of Liraglutide's Risks for Pancreatitis and Cancer
    • accessed 17 June 2011
    • Journal Watch. FDA Reminds Clinicians of Liraglutide's Risks for Pancreatitis and Cancer. http://firstwatch.jwatch.org/cgi/content/full/2011/614/2?q=topic_diabetes accessed 17 June 2011.
    • Journal, W.1
  • 96
    • 77954360414 scopus 로고    scopus 로고
    • Improved glycaemic control with minimal hypoglycaemiaand no weight change with the once-daily humanglucagon-like peptide-1 analogue liraglutide as add-onto sulphonylurea in Japanese patients with type 2 diabetes
    • Kaku K, Rasmussen MF, Clauson P, Seino Y. Improved glycaemic control with minimal hypoglycaemiaand no weight change with the once-daily humanglucagon-like peptide-1 analogue liraglutide as add-onto sulphonylurea in Japanese patients with type 2 diabetes. Diabetes, Obesity and Metabolism 2010;12:341-7.
    • (2010) Diabetes, Obesity and Metabolism , vol.12 , pp. 341-347
    • Kaku, K.1    Rasmussen, M.F.2    Clauson, P.3    Seino, Y.4
  • 98
    • 46149110432 scopus 로고    scopus 로고
    • Efficacy of exenatide therapy over 12 months in a "real world" setting
    • Loh JA, Clement SC. Efficacy of exenatide therapy over 12 months in a "real world" setting. Diabetes 2007;56:A152.
    • (2007) Diabetes , vol.56 , pp. A152
    • Loh, J.A.1    Clement, S.C.2
  • 99
    • 69449100622 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analysis: the PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA group. Preferred reporting items for systematic reviews and meta-analysis: the PRISMA statement. British Medical Journal 2009;339:b2535.
    • (2009) British Medical Journal , vol.339
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 100
    • 66149108722 scopus 로고    scopus 로고
    • Glucagon like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials
    • Monami M, Marchionni N, Mannucci E. Glucagon like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized clinical trials. European Journal of Endocrinology 2009;160:909-17.
    • (2009) European Journal of Endocrinology , vol.160 , pp. 909-917
    • Monami, M.1    Marchionni, N.2    Mannucci, E.3
  • 101
    • 60449089649 scopus 로고    scopus 로고
    • Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • Nathan DM, Buse JB, Davidson MB, Ferrannini E, Holman RR, Sherwin R, et al. American Diabetes Association, European Association for Study of Diabetes. Medical management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2009;32(1):193-03.
    • (2009) Diabetes Care , vol.32 , Issue.1 , pp. 103-193
    • Nathan, D.M.1    Buse, J.B.2    Davidson, M.B.3    Ferrannini, E.4    Holman, R.R.5    Sherwin, R.6
  • 102
    • 0027248866 scopus 로고
    • Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
    • Nauck MA, Kleine N, Orskov C, Holst JJ, Willms B, Creutzfeldt W. Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1993;36(8):741-4.
    • (1993) Diabetologia , vol.36 , Issue.8 , pp. 741-744
    • Nauck, M.A.1    Kleine, N.2    Orskov, C.3    Holst, J.J.4    Willms, B.5    Creutzfeldt, W.6
  • 103
    • 0036959991 scopus 로고    scopus 로고
    • Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycaemic clamp experiments in healthy volunteers
    • Nauck MA, Heimesaat MM, Behle K, Holst JJ, Nauck MS, Ritzel R, et al. Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycaemic clamp experiments in healthy volunteers. The Journal of Clinical Endocrinology and Metabolism 2002;87(3):1239-46.
    • (2002) The Journal of Clinical Endocrinology and Metabolism , vol.87 , Issue.3 , pp. 1239-1246
    • Nauck, M.A.1    Heimesaat, M.M.2    Behle, K.3    Holst, J.J.4    Nauck, M.S.5    Ritzel, R.6
  • 104
    • 85036534435 scopus 로고    scopus 로고
    • Type 2 diabetes: national clinical guideline for management in primary and secondary care
    • National Collaborating Centre for Chronic Conditions. Type 2 diabetes: national clinical guideline for management in primary and secondary care. London: Royal College of Physicians 2008; Vol. http://www.nice.org.uk/nicemedia/pdf/CG66FullGuideline0509.pdf.
    • (2008) London: Royal College of Physicians
  • 105
    • 84920644277 scopus 로고    scopus 로고
    • Type 2 diabetes: the management of type 2 diabetes
    • National Institute for Health and Clinical Excellence. Type 2 diabetes: the management of type 2 diabetes. NICE clinical guideline 87 2009; Vol. http://www.nice.org.uk/cg87.
    • (2009) NICE clinical guideline 87
  • 106
    • 79956152407 scopus 로고    scopus 로고
    • Liraglutide for the treatment of type 2 diabetes mellitus. NICE technology appraisal guidance 203
    • National Institute for Health and Clinical Excellence. Liraglutide for the treatment of type 2 diabetes mellitus. NICE technology appraisal guidance 203. http://guidance.nice.org.uk/TA203 2010.
    • (2010)
  • 108
    • 50949113950 scopus 로고    scopus 로고
    • Overview of glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors for type 2 diabetes
    • Pratley RE. Overview of glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors for type 2 diabetes. Medscape Journal of Medicine 2008;10(7):171.
    • (2008) Medscape Journal of Medicine , vol.10 , Issue.7 , pp. 171
    • Pratley, R.E.1
  • 109
    • 78649800940 scopus 로고    scopus 로고
    • Glucagon-like peptide analogues for type 2 diabetes mellitus: systematic review and meta-analysis
    • Shyangdan DS, Royle PL, Clar C, Sharma P, Waugh NR. Glucagon-like peptide analogues for type 2 diabetes mellitus: systematic review and meta-analysis. BMC Endocrine Disorders 2010;10:20.
    • (2010) BMC Endocrine Disorders , vol.10 , pp. 20
    • Shyangdan, D.S.1    Royle, P.L.2    Clar, C.3    Sharma, P.4    Waugh, N.R.5
  • 111
    • 0029840022 scopus 로고    scopus 로고
    • The UK Prospective Diabetes Study. UK Prospective Diabetes Study Group
    • Turner RC, Holman RR. The UK Prospective Diabetes Study. UK Prospective Diabetes Study Group. Annals of Medicine 1996;28(5):439-44.
    • (1996) Annals of Medicine , vol.28 , Issue.5 , pp. 439-444
    • Turner, R.C.1    Holman, R.R.2
  • 112
    • 0028817815 scopus 로고
    • UKPDS 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. UK Prospective Diabetes Study Group
    • UKPDS Study Group. UKPDS 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. UK Prospective Diabetes Study Group. Diabetes 1995;44:1249-58.
    • (1995) Diabetes , vol.44 , pp. 1249-1258
  • 113
    • 84886943101 scopus 로고    scopus 로고
    • Newer agents for blood glucose control in type 2 diabetes: systematic review and economic evaluation
    • Waugh N, Cummins E, Royle P, Clar C, Marien M, Richter B, et al. Newer agents for blood glucose control in type 2 diabetes: systematic review and economic evaluation. Health Technology Assessment July 2010;14(36):1-248.
    • (2010) Health Technology Assessment , vol.14 , Issue.36 , pp. 1-248
    • Waugh, N.1    Cummins, E.2    Royle, P.3    Clar, C.4    Marien, M.5    Richter, B.6
  • 114
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its compliactions. Part I: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation
    • Alberti KM, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its compliactions. Part I: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabetic Medicine 1998;15:539-53.
    • (1998) Diabetic Medicine , vol.15 , pp. 539-553
    • Alberti, K.M.1    Zimmet, P.Z.2
  • 115
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta- cell mass and improved glucose tolerance in diabetic rats
    • Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta- cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999;48(12):2270-6.
    • (1999) Diabetes , vol.48 , Issue.12 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4


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