Tumour inflammasome-derived IL-1β recruits neutrophils and improves local recurrence-free survival in EBV-induced nasopharyngeal carcinoma

EMBO Molecular Medicine

Volumn 4, Issue 12, 2012, Pages 1276-1293

  Chen, Lih Chyang ^a   Wang, Li Jie ^a   Tsang, Nang Ming ^b   Ojcius, David M ^a,c   Chen, Chia Chun ^a   Ouyang, Chun Nan ^a   Hsueh, Chuen ^a,b   Liang, Ying ^a   Chang, Kai Ping ^b   Chen, Chiu Chin ^a   Chang, Yu Sun ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cancer; Inflammasome; Neutrophil; Prognosis; Therapy

Indexed keywords

CRYOPYRIN; GENOMIC DNA; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN; PROTEIN AIM2; PROTEIN NLRC4; PROTEIN NLRP7; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; VIRUS DNA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE FREE SURVIVAL; EPSTEIN BARR VIRUS; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LOCAL RECURRENCE FREE SURVIVAL; NASOPHARYNX CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; TUMOR MICROENVIRONMENT;

ANIMALS; COHORT STUDIES; HERPESVIRUS 4, HUMAN; HUMANS; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1BETA; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; NASOPHARYNGEAL NEOPLASMS; NEUTROPHIL INFILTRATION; NEUTROPHILS; REACTIVE OXYGEN SPECIES; RETROSPECTIVE STUDIES;

EID: 84872402053     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201569     Document Type: Article

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