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Volumn 27, Issue 1, 2013, Pages 164-170

PI3K and MAPKs Regulate Neutrophil Migration Toward the Airways in Heaves

Author keywords

Horses; Inflammation; Lungs; RAO

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE;

EID: 84872399801     PISSN: 08916640     EISSN: 19391676     Source Type: Journal    
DOI: 10.1111/jvim.12008     Document Type: Article
Times cited : (14)

References (49)
  • 1
    • 0027441715 scopus 로고
    • Early neutrophil but not eosinophil or platelet recruitment to the lungs of allergic horses following antigen exposure
    • Fairbairn SM, Page CP, Lees P, Cunningham FM. Early neutrophil but not eosinophil or platelet recruitment to the lungs of allergic horses following antigen exposure. Clin Exp Allergy 1993;23:821-828.
    • (1993) Clin Exp Allergy , vol.23 , pp. 821-828
    • Fairbairn, S.M.1    Page, C.P.2    Lees, P.3    Cunningham, F.M.4
  • 4
    • 77957259884 scopus 로고    scopus 로고
    • The signaling mechanisms underlying cell polarity and chemotaxis
    • Wang F. The signaling mechanisms underlying cell polarity and chemotaxis. Cold Spring Harb Perspect Biol 2009;1:a002980.
    • (2009) Cold Spring Harb Perspect Biol , vol.1
    • Wang, F.1
  • 5
    • 0025896363 scopus 로고
    • Neutrophil migration induced by equine respiratory secretions, bronchoalveolar lavage fluids and culture supernatants of pulmonary lavage cells
    • Grunig G, Witschi U, Winder C, et al. Neutrophil migration induced by equine respiratory secretions, bronchoalveolar lavage fluids and culture supernatants of pulmonary lavage cells. Vet Immunol Immunopathol 1991;29:313-328.
    • (1991) Vet Immunol Immunopathol , vol.29 , pp. 313-328
    • Grunig, G.1    Witschi, U.2    Winder, C.3
  • 6
    • 0034331454 scopus 로고    scopus 로고
    • Interleukin-8 concentration and neutrophil chemotactic activity in bronchoalveolar lavage fluid of horses with chronic obstructive pulmonary disease following exposure to hay
    • Franchini M, Gill U, von Fellenberg R, Bracher VD. Interleukin-8 concentration and neutrophil chemotactic activity in bronchoalveolar lavage fluid of horses with chronic obstructive pulmonary disease following exposure to hay. Am J Vet Res 2000;61:1369-1374.
    • (2000) Am J Vet Res , vol.61 , pp. 1369-1374
    • Franchini, M.1    Gill, U.2    von Fellenberg, R.3    Bracher, V.D.4
  • 7
    • 0036214186 scopus 로고    scopus 로고
    • Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate
    • Giguere S, Viel L, Lee E, et al. Cytokine induction in pulmonary airways of horses with heaves and effect of therapy with inhaled fluticasone propionate. Vet Immunol Immunopathol 2002;85:147-158.
    • (2002) Vet Immunol Immunopathol , vol.85 , pp. 147-158
    • Giguere, S.1    Viel, L.2    Lee, E.3
  • 8
    • 79960035165 scopus 로고    scopus 로고
    • Cytokine mRNA expression of pulmonary macrophages varies with challenge but not with disease state in horses with heaves or in controls
    • Joubert P, Cordeau ME, Lavoie JP. Cytokine mRNA expression of pulmonary macrophages varies with challenge but not with disease state in horses with heaves or in controls. Vet Immunol Immunopathol 2011;142:236-242.
    • (2011) Vet Immunol Immunopathol , vol.142 , pp. 236-242
    • Joubert, P.1    Cordeau, M.E.2    Lavoie, J.P.3
  • 9
    • 0141428939 scopus 로고    scopus 로고
    • Recurrent airway obstruction (RAO) in horses is characterized by IFN-gamma and IL-8 production in bronchoalveolar lavage cells
    • Ainsworth DM, Grunig G, Matychak MB, et al. Recurrent airway obstruction (RAO) in horses is characterized by IFN-gamma and IL-8 production in bronchoalveolar lavage cells. Vet Immunol Immunopathol 2003;96:83-91.
    • (2003) Vet Immunol Immunopathol , vol.96 , pp. 83-91
    • Ainsworth, D.M.1    Grunig, G.2    Matychak, M.B.3
  • 10
    • 18144362092 scopus 로고    scopus 로고
    • Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx
    • Arndt PG, Young SK, Lieber JG, et al. Inhibition of c-Jun N-terminal kinase limits lipopolysaccharide-induced pulmonary neutrophil influx. Am J Respir Crit Care Med 2005;171:978-986.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 978-986
    • Arndt, P.G.1    Young, S.K.2    Lieber, J.G.3
  • 11
    • 64749093057 scopus 로고    scopus 로고
    • p38 mitogen-activated kinase (MAPK) is essential for equine neutrophil migration
    • Eckert RE, Sharief Y, Jones SL. p38 mitogen-activated kinase (MAPK) is essential for equine neutrophil migration. Vet Immunol Immunopathol 2009;129:181-191.
    • (2009) Vet Immunol Immunopathol , vol.129 , pp. 181-191
    • Eckert, R.E.1    Sharief, Y.2    Jones, S.L.3
  • 12
    • 0142124454 scopus 로고    scopus 로고
    • Signaling to migration in neutrophils: Importance of localized pathways
    • Niggli V. Signaling to migration in neutrophils: Importance of localized pathways. Int J Biochem Cell Biol 2003;35:1619-1638.
    • (2003) Int J Biochem Cell Biol , vol.35 , pp. 1619-1638
    • Niggli, V.1
  • 13
    • 78650883764 scopus 로고    scopus 로고
    • CXCL8 attenuates chemoattractant-induced equine neutrophil migration
    • Brooks AC, Rickards KJ, Cunningham FM. CXCL8 attenuates chemoattractant-induced equine neutrophil migration. Vet Immunol Immunopathol 2011;139(141-147):13.
    • (2011) Vet Immunol Immunopathol , vol.139 , Issue.141-147 , pp. 13
    • Brooks, A.C.1    Rickards, K.J.2    Cunningham, F.M.3
  • 14
    • 84872396937 scopus 로고    scopus 로고
    • Inhaled corticosteroids accelerate the reversal of airway smooth muscle remodeling in an equine model of chronic asthma
    • New Orleans May .A2302
    • Leclere M, Lavoie-Lamoureux A, Martin J, et al. Inhaled corticosteroids accelerate the reversal of airway smooth muscle remodeling in an equine model of chronic asthma. ATS International Conference, New Orleans May 14-19, 2010;A2302.
    • (2010) ATS International Conference , pp. 14-19
    • Leclere, M.1    Lavoie-Lamoureux, A.2    Martin, J.3
  • 15
    • 0036215785 scopus 로고    scopus 로고
    • Comparison of effects of dexamethasone and the leukotriene D4 receptor antagonist L-708,738 on lung function and airway cytologic findings in horses with recurrent airway obstruction
    • Lavoie JP, Leguillette R, Pasloske K, et al. Comparison of effects of dexamethasone and the leukotriene D4 receptor antagonist L-708, 738 on lung function and airway cytologic findings in horses with recurrent airway obstruction. Am J Vet Res 2002;63:579-585.
    • (2002) Am J Vet Res , vol.63 , pp. 579-585
    • Lavoie, J.P.1    Leguillette, R.2    Pasloske, K.3
  • 16
    • 32344431552 scopus 로고    scopus 로고
    • Lack of clinical efficacy of a phosphodiesterase-4 inhibitor for treatment of heaves in horses
    • Lavoie JP, Pasloske K, Joubert P, et al. Lack of clinical efficacy of a phosphodiesterase-4 inhibitor for treatment of heaves in horses. J Vet Intern Med 2006;20:175-181.
    • (2006) J Vet Intern Med , vol.20 , pp. 175-181
    • Lavoie, J.P.1    Pasloske, K.2    Joubert, P.3
  • 17
    • 0032737015 scopus 로고    scopus 로고
    • Monthly, daily, and circadian variations of measurements of pulmonary mechanics in horses with chronic obstructive pulmonary disease
    • Jean D, Vrins A, Lavoie JP. Monthly, daily, and circadian variations of measurements of pulmonary mechanics in horses with chronic obstructive pulmonary disease. Am J Vet Res 1999;60:1341-1346.
    • (1999) Am J Vet Res , vol.60 , pp. 1341-1346
    • Jean, D.1    Vrins, A.2    Lavoie, J.P.3
  • 18
    • 79958034628 scopus 로고    scopus 로고
    • Evaluation of variations in bronchoalveolar lavage fluid in horses with recurrent airway obstruction
    • Jean D, Vrins A, Beauchamp G, Lavoie JP. Evaluation of variations in bronchoalveolar lavage fluid in horses with recurrent airway obstruction. Am J Vet Res 2011;72:838-842.
    • (2011) Am J Vet Res , vol.72 , pp. 838-842
    • Jean, D.1    Vrins, A.2    Beauchamp, G.3    Lavoie, J.P.4
  • 19
    • 0018885287 scopus 로고
    • A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration
    • Falk W, Goodwin RH Jr, Leonard EJ. A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration. J Immunol Methods 1980;33:239-247.
    • (1980) J Immunol Methods , vol.33 , pp. 239-247
    • Falk, W.1    Goodwin Jr., R.H.2    Leonard, E.J.3
  • 20
    • 0014880119 scopus 로고
    • Studies on eosinophil leucocyte migration. II. Factors specifically chemotactic for eosinophils and neutrophils generated from guinea-pig serum by antigen-antibody complexes
    • Kay AB. Studies on eosinophil leucocyte migration. II. Factors specifically chemotactic for eosinophils and neutrophils generated from guinea-pig serum by antigen-antibody complexes. Clin Exp Immunol 1970;7:723-737.
    • (1970) Clin Exp Immunol , vol.7 , pp. 723-737
    • Kay, A.B.1
  • 21
  • 22
    • 50949087902 scopus 로고    scopus 로고
    • Effects of a MAPK p38 inhibitor on lung function and airway inflammation in equine recurrent airway obstruction
    • Lavoie JP, Thompson D, Hamilton E, et al. Effects of a MAPK p38 inhibitor on lung function and airway inflammation in equine recurrent airway obstruction. Equine Vet J 2008;40:577-583.
    • (2008) Equine Vet J , vol.40 , pp. 577-583
    • Lavoie, J.P.1    Thompson, D.2    Hamilton, E.3
  • 23
    • 0035575706 scopus 로고    scopus 로고
    • Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury
    • Yum HK, Arcaroli J, Kupfner J, et al. Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury. J Immunol 2001;167:6601-6608.
    • (2001) J Immunol , vol.167 , pp. 6601-6608
    • Yum, H.K.1    Arcaroli, J.2    Kupfner, J.3
  • 24
    • 77951961401 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung
    • Reutershan J, Saprito MS, Wu D, et al. Phosphoinositide 3-kinase gamma required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung. Eur Respir J 2010;35:1137-1147.
    • (2010) Eur Respir J , vol.35 , pp. 1137-1147
    • Reutershan, J.1    Saprito, M.S.2    Wu, D.3
  • 25
    • 0036838563 scopus 로고    scopus 로고
    • Selective suppression of neutrophil accumulation in ongoing pulmonary inflammation by systemic inhibition of p38 mitogen-activated protein kinase
    • Nick JA, Young SK, Arndt PG, et al. Selective suppression of neutrophil accumulation in ongoing pulmonary inflammation by systemic inhibition of p38 mitogen-activated protein kinase. J Immunol 2002;169:5260-5269.
    • (2002) J Immunol , vol.169 , pp. 5260-5269
    • Nick, J.A.1    Young, S.K.2    Arndt, P.G.3
  • 26
    • 77952758245 scopus 로고    scopus 로고
    • IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation
    • Roussel L, Houle F, Chan C, et al. IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. J Immunol 2010;184:4531-4537.
    • (2010) J Immunol , vol.184 , pp. 4531-4537
    • Roussel, L.1    Houle, F.2    Chan, C.3
  • 27
    • 13844288120 scopus 로고    scopus 로고
    • SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung
    • Underwood DC, Osborn RR, Bochnowicz S, et al. SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. Am J Physiol Lung Cell Mol Physiol 2000;279:L895-L902.
    • (2000) Am J Physiol Lung Cell Mol Physiol , vol.279
    • Underwood, D.C.1    Osborn, R.R.2    Bochnowicz, S.3
  • 28
    • 80053298261 scopus 로고    scopus 로고
    • Emerging mechanisms of neutrophil recruitment across endothelium
    • Williams MR, Azcutia V, Newton G, et al. Emerging mechanisms of neutrophil recruitment across endothelium. Trends Immunol 2011;32:461-469.
    • (2011) Trends Immunol , vol.32 , pp. 461-469
    • Williams, M.R.1    Azcutia, V.2    Newton, G.3
  • 29
    • 0035512544 scopus 로고    scopus 로고
    • Equine neutrophils express mRNA for tumour necrosis factor-alpha, interleukin (IL)-1beta, IL-6, IL-8, macrophage-inflammatory-protein-2 but not for IL-4, IL-5 and interferon-gamma
    • Joubert P, Silversides DW, Lavoie JP. Equine neutrophils express mRNA for tumour necrosis factor-alpha, interleukin (IL)-1beta, IL-6, IL-8, macrophage-inflammatory-protein-2 but not for IL-4, IL-5 and interferon-gamma. Equine Vet J 2001;33:730-733.
    • (2001) Equine Vet J , vol.33 , pp. 730-733
    • Joubert, P.1    Silversides, D.W.2    Lavoie, J.P.3
  • 30
    • 37249051855 scopus 로고    scopus 로고
    • Effects of in vitro exposure to hay dust on expression of interleukin-17, -23, -8, and -1beta and chemokine (C-X-C motif) ligand 2 by pulmonary mononuclear cells isolated from horses chronically affected with recurrent airway disease
    • Ainsworth DM, Wagner B, Erb HN, et al. Effects of in vitro exposure to hay dust on expression of interleukin-17, -23, -8, and -1beta and chemokine (C-X-C motif) ligand 2 by pulmonary mononuclear cells isolated from horses chronically affected with recurrent airway disease. Am J Vet Res 2007;68:1361-1369.
    • (2007) Am J Vet Res , vol.68 , pp. 1361-1369
    • Ainsworth, D.M.1    Wagner, B.2    Erb, H.N.3
  • 31
    • 63249110290 scopus 로고    scopus 로고
    • Effects of in vitro exposure to hay dust on the gene expression of chemokines and cell-surface receptors in primary bronchial epithelial cell cultures established from horses with chronic recurrent airway obstruction
    • Ainsworth DM, Matychak M, Reyner CL, et al. Effects of in vitro exposure to hay dust on the gene expression of chemokines and cell-surface receptors in primary bronchial epithelial cell cultures established from horses with chronic recurrent airway obstruction. Am J Vet Res 2009;70:365-372.
    • (2009) Am J Vet Res , vol.70 , pp. 365-372
    • Ainsworth, D.M.1    Matychak, M.2    Reyner, C.L.3
  • 32
    • 0036017292 scopus 로고    scopus 로고
    • Evaluation of leukotriene biosynthetic capacity in lung tissues from horses with recurrent airway obstruction
    • Lindberg A, Nasman-Glaser B, Lindgren JA, Robinson NE. Evaluation of leukotriene biosynthetic capacity in lung tissues from horses with recurrent airway obstruction. Am J Vet Res 2002;63:794-798.
    • (2002) Am J Vet Res , vol.63 , pp. 794-798
    • Lindberg, A.1    Nasman-Glaser, B.2    Lindgren, J.A.3    Robinson, N.E.4
  • 33
    • 0032059761 scopus 로고    scopus 로고
    • Inhaled leukotrienes cause bronchoconstriction and neutrophil accumulation in horses
    • Marr KA, Lees P, Page CP, Cunningham FM. Inhaled leukotrienes cause bronchoconstriction and neutrophil accumulation in horses. Res Vet Sci 1998;64:219-224.
    • (1998) Res Vet Sci , vol.64 , pp. 219-224
    • Marr, K.A.1    Lees, P.2    Page, C.P.3    Cunningham, F.M.4
  • 34
    • 0033430377 scopus 로고    scopus 로고
    • Reversal of human neutrophil survival by leukotriene B(4) receptor blockade and 5-lipoxygenase and 5-lipoxygenase activating protein inhibitors
    • Lee E, Lindo T, Jackson N, et al. Reversal of human neutrophil survival by leukotriene B(4) receptor blockade and 5-lipoxygenase and 5-lipoxygenase activating protein inhibitors. Am J Respir Crit Care Med 1999;160:2079-2085.
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 2079-2085
    • Lee, E.1    Lindo, T.2    Jackson, N.3
  • 35
    • 22144438655 scopus 로고    scopus 로고
    • TNF-alpha promotes a stop signal that inhibits neutrophil polarization and migration via a p38 MAPK pathway
    • Lokuta MA, Huttenlocher A. TNF-alpha promotes a stop signal that inhibits neutrophil polarization and migration via a p38 MAPK pathway. J Leuk Biol 2005;78:210-219.
    • (2005) J Leuk Biol , vol.78 , pp. 210-219
    • Lokuta, M.A.1    Huttenlocher, A.2
  • 36
    • 77957326613 scopus 로고    scopus 로고
    • IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo
    • Lavoie-Lamoureux A, Moran K, Beauchamp G, et al. IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo. Am J Physiol Lung Cell Mol Physiol 2010;299:L472-482.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.299
    • Lavoie-Lamoureux, A.1    Moran, K.2    Beauchamp, G.3
  • 37
    • 0026777610 scopus 로고
    • Selective induction of intercellular adhesion molecule-1 by interferon-gamma in human airway epithelial cells
    • Look DC, Rapp SR, Keller BT, Holtzman MJ. Selective induction of intercellular adhesion molecule-1 by interferon-gamma in human airway epithelial cells. Am J Physiol 1992;263:L79-L87.
    • (1992) Am J Physiol , vol.263
    • Look, D.C.1    Rapp, S.R.2    Keller, B.T.3    Holtzman, M.J.4
  • 38
    • 80555133279 scopus 로고    scopus 로고
    • IL-1alpha and IL-1beta recruit different myeloid cells and promote different stages of sterile inflammation
    • Rider P, Carmi Y, Guttman O, et al. IL-1alpha and IL-1beta recruit different myeloid cells and promote different stages of sterile inflammation. J Immunol 2011;187:4835-4843.
    • (2011) J Immunol , vol.187 , pp. 4835-4843
    • Rider, P.1    Carmi, Y.2    Guttman, O.3
  • 39
    • 0034086432 scopus 로고    scopus 로고
    • Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression
    • Krunkosky TM, Fischer BM, Martin LD, et al. Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. Am J Respir Cell Mol Biol 2000;22:685-692.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 685-692
    • Krunkosky, T.M.1    Fischer, B.M.2    Martin, L.D.3
  • 40
    • 33745028391 scopus 로고    scopus 로고
    • Rapid, multiwell colorimetric assay for measuring neutrophil chemoattractant activity in bronchoalveolar lavage fluid of horses with recurrent airway obstruction
    • Hall JA, Hoyt D, Zuver C, et al. Rapid, multiwell colorimetric assay for measuring neutrophil chemoattractant activity in bronchoalveolar lavage fluid of horses with recurrent airway obstruction. J Vet Diagn Invest 2006;18:257-263.
    • (2006) J Vet Diagn Invest , vol.18 , pp. 257-263
    • Hall, J.A.1    Hoyt, D.2    Zuver, C.3
  • 41
    • 0032491373 scopus 로고    scopus 로고
    • The role of neutrophil chemotactic cytokines in the pathogenesis of equine chronic obstructive pulmonary disease (COPD)
    • Franchini M, Gilli U, Akens MK, et al. The role of neutrophil chemotactic cytokines in the pathogenesis of equine chronic obstructive pulmonary disease (COPD). Vet Immunol Immunopathol 1998;66:53-65.
    • (1998) Vet Immunol Immunopathol , vol.66 , pp. 53-65
    • Franchini, M.1    Gilli, U.2    Akens, M.K.3
  • 42
    • 21244504902 scopus 로고    scopus 로고
    • Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils
    • Chen LW, Lin MW, Hsu CM. Different pathways leading to activation of extracellular signal-regulated kinase and p38 MAP kinase by formyl-methionyl-leucyl-phenylalanine or platelet activating factor in human neutrophils. J Biomed Sci 2005;12:311-319.
    • (2005) J Biomed Sci , vol.12 , pp. 311-319
    • Chen, L.W.1    Lin, M.W.2    Hsu, C.M.3
  • 43
    • 0035145860 scopus 로고    scopus 로고
    • N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells
    • Hashimoto S, Gon Y, Matsumoto K, et al. N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells. Br J Pharmacol 2001;132:270-276.
    • (2001) Br J Pharmacol , vol.132 , pp. 270-276
    • Hashimoto, S.1    Gon, Y.2    Matsumoto, K.3
  • 44
    • 84862812798 scopus 로고    scopus 로고
    • Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease
    • Kim SR, Lee KS, Park SJ, et al. Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease. J Clin Immunol 2012;32(3):574-586.
    • (2012) J Clin Immunol , vol.32 , Issue.3 , pp. 574-586
    • Kim, S.R.1    Lee, K.S.2    Park, S.J.3
  • 45
    • 77953633984 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: Role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways
    • Shan L, Redhu NS, Saleh A, et al. Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: Role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways. J Immunol 2010;184:7134-7143.
    • (2010) J Immunol , vol.184 , pp. 7134-7143
    • Shan, L.1    Redhu, N.S.2    Saleh, A.3
  • 46
    • 79952116012 scopus 로고    scopus 로고
    • Pro-inflammatory angiogenesis is mediated by p38 MAP kinase
    • Rajashekhar G, Kamocka M, Marin A, et al. Pro-inflammatory angiogenesis is mediated by p38 MAP kinase. J Cell Physiol 2011;226:800-808.
    • (2011) J Cell Physiol , vol.226 , pp. 800-808
    • Rajashekhar, G.1    Kamocka, M.2    Marin, A.3
  • 47
    • 70350028721 scopus 로고    scopus 로고
    • Regulation of JNK and p38 MAPK in the immune system: Signal integration, propagation and termination
    • Huang G, Shi LZ, Chi H. Regulation of JNK and p38 MAPK in the immune system: Signal integration, propagation and termination. Cytokine 2009;48:161-169.
    • (2009) Cytokine , vol.48 , pp. 161-169
    • Huang, G.1    Shi, L.Z.2    Chi, H.3
  • 48
    • 38849139073 scopus 로고    scopus 로고
    • Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase isoforms for neutrophil recruitment induced by chemoattractants in vivo
    • Pinho V, Russo RC, Amaral FA, et al. Tissue- and stimulus-dependent role of phosphatidylinositol 3-kinase isoforms for neutrophil recruitment induced by chemoattractants in vivo. J Immunol 2007;179:7891-7898.
    • (2007) J Immunol , vol.179 , pp. 7891-7898
    • Pinho, V.1    Russo, R.C.2    Amaral, F.A.3
  • 49
    • 20244364825 scopus 로고    scopus 로고
    • Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases
    • Thomas MJ, Smith A, Head DH, et al. Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases. Eur J Immunol 2005;35:1283-1291.
    • (2005) Eur J Immunol , vol.35 , pp. 1283-1291
    • Thomas, M.J.1    Smith, A.2    Head, D.H.3


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