IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 299, Issue 4, 2010, Pages

  Lavoie Lamoureux, Anouk ^a   Moran, Kantuta ^a   Beauchamp, Guy ^a   Mauel, Susanne ^b   Steinbach, Falko ^c   Lefebvre Lavoie, Josiane ^a   Martin, James G ^d   Lavoie, Jean Pierre ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c VETERINARY LABORATORIES AGENCY   (United Kingdom)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

Allergy; Cytokines; Equine asthma

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CHEMOTACTIC FACTOR; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; RECOMBINANT INTERLEUKIN 4; STAT6 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; STAT6 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; CELL ACTIVATION; CELL ISOLATION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE TIME EFFECT RELATION; ENDOTHELIUM CELL; EX VIVO STUDY; GENE EXPRESSION; HORSE; INFLAMMATION; LONG TERM EXPOSURE; LUNG ENDOTHELIUM; MEDIATOR RELEASE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NEUTROPHILIA; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RESPIRATORY TRACT INFLAMMATION; SUPERNATANT; TH2 CELL; UPREGULATION; ANIMAL; ENZYME IMMUNOASSAY; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; LEUKOCYTE ACTIVATION; METABOLISM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ASTHMA; BLOTTING, WESTERN; CHEMOTAXIS, LEUKOCYTE; GENE EXPRESSION PROFILING; HORSES; IMMUNOENZYME TECHNIQUES; INFLAMMATION; INTERLEUKIN-4; INTERLEUKIN-8; NEUTROPHIL ACTIVATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAT6 TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR-ALPHA; PHOSPHATIDYLINOSITOL 3-KINASES;

EID: 77957326613     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00135.2009     Document Type: Article

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