메뉴 건너뛰기




Volumn 319, Issue 3, 2013, Pages 77-88

MicroRNA-1 targets Slug and endows lung cancer A549 cells with epithelial and anti-tumorigenic properties

Author keywords

A549 cells; Adherens junction; E cadherin; MiR 1; Slug

Indexed keywords

DOXORUBICIN; LUCIFERASE; MICRORNA 1; OCCLUDIN; TRANSCRIPTION FACTOR SLUG; UVOMORULIN; VINCULIN;

EID: 84872380374     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2012.10.015     Document Type: Article
Times cited : (35)

References (51)
  • 3
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis
    • Yang J., Weinberg R.A. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell. 2008, 14:818-829.
    • (2008) Dev. Cell. , vol.14 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 4
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery J.P., Acloque H., Huang R.Y., Nieto M.A. Epithelial-mesenchymal transitions in development and disease. Cell 2009, 139:871-890.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 5
    • 34249315460 scopus 로고    scopus 로고
    • Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells
    • Funasaka T., Hu H., Yanagawa T., Hogan V., Raz A. Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells. Cancer Res. 2007, 67:4236-4243.
    • (2007) Cancer Res. , vol.67 , pp. 4236-4243
    • Funasaka, T.1    Hu, H.2    Yanagawa, T.3    Hogan, V.4    Raz, A.5
  • 6
    • 60549108144 scopus 로고    scopus 로고
    • Clusterin silencing in human lung adenocarcinoma cells induces a mesenchymal-to-epithelial transition through modulating the ERK/Slug pathway
    • Chou T.Y., Chen W.C., Lee A.C., Hung S.M., Shih N.Y., Chen M.Y. Clusterin silencing in human lung adenocarcinoma cells induces a mesenchymal-to-epithelial transition through modulating the ERK/Slug pathway. Cell. Signal 2009, 21:704-711.
    • (2009) Cell. Signal , vol.21 , pp. 704-711
    • Chou, T.Y.1    Chen, W.C.2    Lee, A.C.3    Hung, S.M.4    Shih, N.Y.5    Chen, M.Y.6
  • 8
    • 27144477683 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition
    • Thomson S., Buck E., Petti F., Griffin G., Brown E., Ramnarine N., Iwata K.K., Gibson N., Haley J.D. Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition. Cancer Res. 2005, 65:9455-9462.
    • (2005) Cancer Res. , vol.65 , pp. 9455-9462
    • Thomson, S.1    Buck, E.2    Petti, F.3    Griffin, G.4    Brown, E.5    Ramnarine, N.6    Iwata, K.K.7    Gibson, N.8    Haley, J.D.9
  • 10
    • 0142173075 scopus 로고    scopus 로고
    • Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells
    • Saxena S., Jónsson Z.O., Dutta A. Small RNAs with imperfect match to endogenous mRNA repress translation. Implications for off-target activity of small inhibitory RNA in mammalian cells. J. Biol. Chem. 2003, 278:44312-44319.
    • (2003) J. Biol. Chem. , vol.278 , pp. 44312-44319
    • Saxena, S.1    Jónsson, Z.O.2    Dutta, A.3
  • 11
    • 22144478256 scopus 로고    scopus 로고
    • MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies
    • Liu J., Valencia-Sanchez M.A., Hannon G.J., Parker R. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nat. Cell. Biol. 2005, 7:719-723.
    • (2005) Nat. Cell. Biol. , vol.7 , pp. 719-723
    • Liu, J.1    Valencia-Sanchez, M.A.2    Hannon, G.J.3    Parker, R.4
  • 12
    • 57749089758 scopus 로고    scopus 로고
    • Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
    • Nasser M.W., Datta J., Nuovo G., Kutay H., Motiwala T., Majumder S., Wang B., Suster S., Jacob S.T., Ghoshal K. Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1. J. Biol. Chem. 2008, 283:33394-33405.
    • (2008) J. Biol. Chem. , vol.283 , pp. 33394-33405
    • Nasser, M.W.1    Datta, J.2    Nuovo, G.3    Kutay, H.4    Motiwala, T.5    Majumder, S.6    Wang, B.7    Suster, S.8    Jacob, S.T.9    Ghoshal, K.10
  • 16
    • 0030868453 scopus 로고    scopus 로고
    • Unanticipated temporal and spatial effects of sarcomeric alpha-actinin peptides expressed in PtK2 cells
    • Hijikata T., Lin Z.X., Holtzer S., Choi J., Sweeney H.L., Holtzer H. Unanticipated temporal and spatial effects of sarcomeric alpha-actinin peptides expressed in PtK2 cells. Cell. Motil. Cytoskeleton 1997, 38:54-74.
    • (1997) Cell. Motil. Cytoskeleton , vol.38 , pp. 54-74
    • Hijikata, T.1    Lin, Z.X.2    Holtzer, S.3    Choi, J.4    Sweeney, H.L.5    Holtzer, H.6
  • 17
    • 0013523644 scopus 로고
    • Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membrane
    • Geiger B., Tokuyasu K.T., Dutton A.H., Singer S.J. Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membrane. Proc. Nat. Acad. Sci. U.S.A. 1980, 77:4127-4131.
    • (1980) Proc. Nat. Acad. Sci. U.S.A. , vol.77 , pp. 4127-4131
    • Geiger, B.1    Tokuyasu, K.T.2    Dutton, A.H.3    Singer, S.J.4
  • 18
    • 0032482254 scopus 로고    scopus 로고
    • Vinculin is part of the cadherin-catenin junctional complex: Complex formation between a-catenin and vinculin
    • Weiss E.E., Kroemker M., Rüdiger A.-H., Jockusch B.M., Rüdiger M. Vinculin is part of the cadherin-catenin junctional complex: Complex formation between a-catenin and vinculin. J. Cell. Biol. 1998, 141:755-764.
    • (1998) J. Cell. Biol. , vol.141 , pp. 755-764
    • Weiss, E.E.1    Kroemker, M.2    Rüdiger, A.-H.3    Jockusch, B.M.4    Rüdiger, M.5
  • 19
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumor progression: an alliance against the epithelial phnotype?
    • Peinado H., Olmeda M., Cano A. Snail, Zeb and bHLH factors in tumor progression: an alliance against the epithelial phnotype?. Nat. Rev. Cancer 2007, 7:415-428.
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, M.2    Cano, A.3
  • 20
    • 30044437240 scopus 로고    scopus 로고
    • MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling
    • Kwon C., Han Z., Olson E.N., Srivastava D. MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc. Nat. Acad. Sci. U.S.A. 2005, 102:18986-18991.
    • (2005) Proc. Nat. Acad. Sci. U.S.A. , vol.102 , pp. 18986-18991
    • Kwon, C.1    Han, Z.2    Olson, E.N.3    Srivastava, D.4
  • 25
    • 84872406194 scopus 로고    scopus 로고
    • Slug contributes to cadherin switch and malignant progression in muscle-invasive bladder cancer development
    • Wu K., Zeng J., Zhou J., Fan J., Chen Y., Wang Z., Zhang T., Wang X., He D. Slug contributes to cadherin switch and malignant progression in muscle-invasive bladder cancer development. Urol. Oncol. 2012, 12:91.
    • (2012) Urol. Oncol. , vol.12 , pp. 91
    • Wu, K.1    Zeng, J.2    Zhou, J.3    Fan, J.4    Chen, Y.5    Wang, Z.6    Zhang, T.7    Wang, X.8    He, D.9
  • 26
    • 0037086277 scopus 로고    scopus 로고
    • The Slug zinc-finger protein represses E-cadherin in breast cancer
    • Hajra K.M., Chen D.Y., Fearon E.R. The Slug zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 2002, 62:1613-1618.
    • (2002) Cancer Res. , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 27
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
    • Bolós V., Peinado H., Pérez-Moreno M.A., Fraga M.F., Esteller M., Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J. Cell. Sci. 2003, 116:499-511.
    • (2003) J. Cell. Sci. , vol.116 , pp. 499-511
    • Bolós, V.1    Peinado, H.2    Pérez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 29
    • 33847282998 scopus 로고    scopus 로고
    • Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor Slug
    • Wang Z., Wade P., Mandell K.J., Akyildiz A., Parkos C.A., Mrsny R.J., Nusrat A. Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor Slug. Oncogene 2007, 26:1222-1230.
    • (2007) Oncogene , vol.26 , pp. 1222-1230
    • Wang, Z.1    Wade, P.2    Mandell, K.J.3    Akyildiz, A.4    Parkos, C.A.5    Mrsny, R.J.6    Nusrat, A.7
  • 30
    • 79952075985 scopus 로고    scopus 로고
    • Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling
    • Zhang K., Chen D., Jiao X., Zhang S., Liu X., Cao J., Wu L., Wang D. Slug enhances invasion ability of pancreatic cancer cells through upregulation of matrix metalloproteinase-9 and actin cytoskeleton remodeling. Lab. Invest. 2011, 91:426-438.
    • (2011) Lab. Invest. , vol.91 , pp. 426-438
    • Zhang, K.1    Chen, D.2    Jiao, X.3    Zhang, S.4    Liu, X.5    Cao, J.6    Wu, L.7    Wang, D.8
  • 31
    • 79956227342 scopus 로고    scopus 로고
    • Slug down-regulation by RNA interference inhibits invasion growth in human esophageal squamous cell carcinoma
    • Tang P., Yu Z., Zhang K., Wang Y., Ma Z., Zhang S., Chen D., Zhou Y. Slug down-regulation by RNA interference inhibits invasion growth in human esophageal squamous cell carcinoma. BMC Gastroenterol. 2011, 11:60.
    • (2011) BMC Gastroenterol. , vol.11 , pp. 60
    • Tang, P.1    Yu, Z.2    Zhang, K.3    Wang, Y.4    Ma, Z.5    Zhang, S.6    Chen, D.7    Zhou, Y.8
  • 32
    • 12944260524 scopus 로고    scopus 로고
    • Developmental transcription factor Slug is required for effective re-epithelialization by adult keratinocytes
    • Savagner P., Kusewitt D.F., Carver E.A., Magnino F., Choi C., Gridley T., Hudson L.G. Developmental transcription factor Slug is required for effective re-epithelialization by adult keratinocytes. J. Cell. Physiol. 2005, 202:858-866.
    • (2005) J. Cell. Physiol. , vol.202 , pp. 858-866
    • Savagner, P.1    Kusewitt, D.F.2    Carver, E.A.3    Magnino, F.4    Choi, C.5    Gridley, T.6    Hudson, L.G.7
  • 33
    • 80755143039 scopus 로고    scopus 로고
    • Slug promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis
    • Uygur B., Wu W.S. Slug promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis. Mol. Cancer 2011, 10:139.
    • (2011) Mol. Cancer , vol.10 , pp. 139
    • Uygur, B.1    Wu, W.S.2
  • 36
    • 80054784515 scopus 로고    scopus 로고
    • The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer
    • Dhasarathy A., Phadke D., Mav D., Shah R.R., Wade P.A. The transcription factors Snail and Slug activate the transforming growth factor-beta signaling pathway in breast cancer. PLoS One 2011, 6:e26514.
    • (2011) PLoS One , vol.6
    • Dhasarathy, A.1    Phadke, D.2    Mav, D.3    Shah, R.R.4    Wade, P.A.5
  • 37
    • 80054076679 scopus 로고    scopus 로고
    • MiRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line
    • Wang F., Song G., Liu M., Li X., Tang H. miRNA-1 targets fibronectin1 and suppresses the migration and invasion of the HEp2 laryngeal squamous carcinoma cell line. FEBS Lett. 2011, 585:3263-3269.
    • (2011) FEBS Lett. , vol.585 , pp. 3263-3269
    • Wang, F.1    Song, G.2    Liu, M.3    Li, X.4    Tang, H.5
  • 38
    • 70449732503 scopus 로고    scopus 로고
    • Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer
    • Roy R., Yang J, Moses M.A. Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer. J. Clin. Oncol. 2009, 27:5287-5297.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5287-5297
    • Roy, R.1    Yang, J.2    Moses, M.A.3
  • 40
    • 36148932553 scopus 로고    scopus 로고
    • Chemokines: novel targets for breast cancer metastasis
    • Ali S., Lazennec G. Chemokines: novel targets for breast cancer metastasis. Cancer Metastasis Rev. 2007, 26:401-420.
    • (2007) Cancer Metastasis Rev. , vol.26 , pp. 401-420
    • Ali, S.1    Lazennec, G.2
  • 43
    • 33745086313 scopus 로고    scopus 로고
    • Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
    • Shioiri M., Shida T., Koda K., Oda K., Seike K., Nishimura M., Takano S., Miyazaki M. Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients. Br. J. Cancer 2006, 94:1816-1822.
    • (2006) Br. J. Cancer , vol.94 , pp. 1816-1822
    • Shioiri, M.1    Shida, T.2    Koda, K.3    Oda, K.4    Seike, K.5    Nishimura, M.6    Takano, S.7    Miyazaki, M.8
  • 46
    • 27744547091 scopus 로고    scopus 로고
    • Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma
    • Wu W.S., Heinrichs S., Xu D., Garrison S.P., Zambetti G.P., Adams J.M., Look A.T. Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 2005, 123:641-653.
    • (2005) Cell , vol.123 , pp. 641-653
    • Wu, W.S.1    Heinrichs, S.2    Xu, D.3    Garrison, S.P.4    Zambetti, G.P.5    Adams, J.M.6    Look, A.T.7
  • 48
    • 84655165026 scopus 로고    scopus 로고
    • Slug regulates proliferation and invasiveness of esophageal adenocarcinoma cells in vitro and in vivo
    • Zhang K., Zhang S., Jiao X., Wang H., Zhang D., Niu Z., Shen Y., Lv L., Zhou Y. Slug regulates proliferation and invasiveness of esophageal adenocarcinoma cells in vitro and in vivo. Med. Oncol. 2011, 28:1089-1100.
    • (2011) Med. Oncol. , vol.28 , pp. 1089-1100
    • Zhang, K.1    Zhang, S.2    Jiao, X.3    Wang, H.4    Zhang, D.5    Niu, Z.6    Shen, Y.7    Lv, L.8    Zhou, Y.9
  • 49
    • 79251610744 scopus 로고    scopus 로고
    • RNA Interference Targeting Slug Increases Cholangiocarcinoma Cell Sensitivity to Cisplatin via Upregulating PUMA
    • Zhang K., Chen D., Wang X., Zhang S., Wang J., Gao Y., Yan B. RNA Interference Targeting Slug Increases Cholangiocarcinoma Cell Sensitivity to Cisplatin via Upregulating PUMA. Int. J. Mol. Sci. 2011, 12:385-400.
    • (2011) Int. J. Mol. Sci. , vol.12 , pp. 385-400
    • Zhang, K.1    Chen, D.2    Wang, X.3    Zhang, S.4    Wang, J.5    Gao, Y.6    Yan, B.7
  • 50
    • 34447136179 scopus 로고    scopus 로고
    • Short interfering RNA directed against the Slug gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine
    • Vannini I., Bonafe M., Tesei A., Rosetti M., Fabbri F., Storci G., Ulivi P., Brigliadori G., Amadori D., Zoli W. Short interfering RNA directed against the Slug gene increases cell death induction in human melanoma cell lines exposed to cisplatin and fotemustine. Cell. Oncol. 2007, 29:279-287.
    • (2007) Cell. Oncol. , vol.29 , pp. 279-287
    • Vannini, I.1    Bonafe, M.2    Tesei, A.3    Rosetti, M.4    Fabbri, F.5    Storci, G.6    Ulivi, P.7    Brigliadori, G.8    Amadori, D.9    Zoli, W.10
  • 51
    • 84861617311 scopus 로고    scopus 로고
    • Prognostic Role of Twist, Slug, and Foxc2 Expression in Stage I Non-Small-Cell Lung Cancer After Curative Resection
    • Jiang W., Pang X.G., Wang Q., Shen Y.X., Chen X X.K., Xi J.J. Prognostic Role of Twist, Slug, and Foxc2 Expression in Stage I Non-Small-Cell Lung Cancer After Curative Resection. Clin. Lung. Cancer 2012, 13:280-287.
    • (2012) Clin. Lung. Cancer , vol.13 , pp. 280-287
    • Jiang, W.1    Pang, X.G.2    Wang, Q.3    Shen, Y.X.4    Chen, X.X.K.5    Xi, J.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.