Slug expression enhances tumor formation in a noninvasive rectal cancer model

Journal of Surgical Research

Volumn 170, Issue 1, 2011, Pages 56-63

  Camp, E Ramsay ^a,c   Findlay, Victoria J ^a,b   Vaena, Silvia G ^a   Walsh, Jarret ^a   Lewin, David N ^a   Turner, David P ^a,b   Watson, Dennis K ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

colorectal cancer; e cadherin; rectal tumor model; slug

Indexed keywords

TRANSCRIPTION FACTOR SLUG; UVOMORULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CANCER MODEL; CANCER TISSUE; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM CANCER; TUMOR PROMOTION;

ANIMALS; CADHERINS; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; HUMANS; MICE; RECTAL NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 80051548247     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2011.02.012     Document Type: Article

References (20)

1. H. Acloque, M.S. Adams, and K. Fishwick Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease J Clin Invest 119 2009 1438
2. J.P. Thiery, and J.P. Sleeman Complex networks orchestrate epithelial-mesenchymal transitions Nat Rev 7 2006 131
3. J.P. Thiery, H. Acloque, and R.Y. Huang Epithelial-mesenchymal transitions in development and disease Cell 139 2009 871
4. D. Olmeda, G. Moreno-Bueno, and J.M. Flores SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells Cancer Res 67 2007 11721
5. M. Leptin Twist and snail as positive and negative regulators during Drosophila mesoderm development Genes Dev 5 1991 1568
6. M. Kajita, K.N. McClinic, and P.A. Wade Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress Mol Cell Biol 24 2004 7559
7. C. Tribulo, M.J. Aybar, and S.S. Sanchez Balance between the anti-apoptotic activity of Slug and the apoptotic activity of msx1 is required for the proper development of the neural crest Dev Biology 275 2004 325
8. M.V. Cespedes, C. Espina, and M.A. Garcia-Cabezas Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites Am J Pathol 170 2007 1077
9. T.W. Bauer, F. Fan, and W. Liu Targeting of insulin-like growth factor-I receptor with a monoclonal antibody inhibits growth of hepatic metastases from human colon carcinoma in mice Ann Surg Oncol 14 2007 2838
10. M. Donigan, L.S. Norcross, and J. Aversa Novel murine model for colon cancer: Non-operative trans-anal rectal injection J Surg Res 154 2009 299
11. S. Gagos, V.L. Hopwood, and D. Iliopoulos Chromosomal markers associated with metastasis in two colon cancer cell lines established from the same patient Anticancer Res 15 1995 369
12. L. Maehle, E. Eilertsen, and S. Mollerup Effects of n-3 fatty acids during neoplastic progression and comparison of in vitro and in vivo sensitivity of two human tumor cell lines Br J Cancer 71 1995 691
13. I. Tatar, P.C. Chou, and M.M. Desouki Evaluating regional blood spinal cord barrier dysfunction following spinal cord injury using longitudinal dynamic contrast-enhanced MRI BMC Med Imaging 9 2009 10
14. G.C. Balch, A. De Meo, and J.G. Guillem Modern management of rectal cancer: A 2006 update World J Gastroenterol 12 2006 3186
15. J.G. Guillem, D.B. Chessin, and A.M. Cohen Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer Ann Surg 241 2005 829 discussion 836
16. H. Sasaki, K. Miura, and A. Horii Orthotopic implantation mouse model and cDNA microarray analysis indicates several genes potentially involved in lymph node metastasis of colorectal cancer Cancer Sci 99 2008 711
17. E. Batlle, E. Sancho, and C. Franci The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells Nat Cell Biol 2 2000 84
18. A. Cano, M.A. Perez-Moreno, and I. Rodrigo The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression Nat Cell Biol 2 2000 76
19. S. Vega, A.V. Morales, and O.H. Ocana Snail blocks the cell cycle and confers resistance to cell death Genes Dev 18 2004 1131
20. A.D. Yang, F. Fan, and E.R. Camp Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines Clin Cancer Res 12 2006 4147