-
1
-
-
33750354299
-
NADPH oxidase-derived ROS: Key modulators of heme-induced mitochondrial stability in human neutrophils
-
Arruda MA, Barcellos-de-Souza P., Sampaio AL, Rossi AG, Graca-Souza AV, Barja-Fidalgo C. NADPH oxidase-derived ROS: key modulators of heme-induced mitochondrial stability in human neutrophils. Exp Cell Res 312: 3939-3948, 2006.
-
(2006)
Exp Cell Res
, vol.312
, pp. 3939-3948
-
-
Arruda, M.A.1
Barcellos-de-Souza, P.2
Sampaio, A.L.3
Rossi, A.G.4
Graca-Souza, A.V.5
Barja-Fidalgo, C.6
-
2
-
-
3242741986
-
Heme inhibits human neutrophil apoptosis: Involvement of phosphoinositide 3-kinase, MAPK, and NF-kappaB
-
Arruda MA, Rossi AG, de Freitas MS, Barja-Fidalgo C, Graca-Souza AV. Heme inhibits human neutrophil apoptosis: involvement of phosphoinositide 3-kinase, MAPK, and NF-kappaB. J Immunol 173: 2023-2030, 2004.
-
(2004)
J Immunol
, vol.173
, pp. 2023-2030
-
-
Arruda, M.A.1
Rossi, A.G.2
de Freitas, M.S.3
Barja-Fidalgo, C.4
Graca-Souza, A.V.5
-
3
-
-
18344410191
-
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in crohn disease and experimental colitis in vivo
-
Atreya R, Mudter J, Finotto S, Mullberg J, Jostock T, Wirtz S, Schutz M, Bartsch B, Holtmann M, Becker C, Strand D, Czaja J, Schlaak JF, Lehr HA, Autschbach F, Schurmann G, Nishimoto N, Yoshizaki K, Ito H, Kishimoto T, Galle PR, Rose-John S, Neurath MF. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo. Nat Med 6: 583-588, 2000.
-
(2000)
Nat Med
, vol.6
, pp. 583-588
-
-
Atreya, R.1
Mudter, J.2
Finotto, S.3
Mullberg, J.4
Jostock, T.5
Wirtz, S.6
Schutz, M.7
Bartsch, B.8
Holtmann, M.9
Becker, C.10
Strand, D.11
Czaja, J.12
Schlaak, J.F.13
Lehr, H.A.14
Autschbach, F.15
Schurmann, G.16
Nishimoto, N.17
Yoshizaki, K.18
Ito, H.19
Kishimoto, T.20
Galle, P.R.21
Rose-John, S.22
Neurath, M.F.23
more..
-
4
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 87: 245-313, 2007.
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
5
-
-
58649101347
-
Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
Bollrath J, Phesse TJ, von Burstin VA, Putoczki T, Bennecke M, Bateman T, Nebelsiek T, Lundgren-May T, Canli O, Schwitalla S, Matthews V, Schmid RM, Kirchner T, Arkan MC, Ernst M, Greten FR. Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15: 91-102, 2009.
-
(2009)
Cancer Cell
, vol.15
, pp. 91-102
-
-
Bollrath, J.1
Phesse, T.J.2
von Burstin, V.A.3
Putoczki, T.4
Bennecke, M.5
Bateman, T.6
Nebelsiek, T.7
Lundgren-May, T.8
Canli, O.9
Schwitalla, S.10
Matthews, V.11
Schmid, R.M.12
Kirchner, T.13
Arkan, M.C.14
Ernst, M.15
Greten, F.R.16
-
6
-
-
70450064812
-
Mucosal immunity: Induction, dissemination, and effector functions
-
Brandtzaeg P. Mucosal immunity: induction, dissemination, and effector functions. Scandinavian J Immunol 70: 505-515, 2009.
-
(2009)
Scandinavian J Immunol
, vol.70
, pp. 505-515
-
-
Brandtzaeg, P.1
-
7
-
-
44849122358
-
Protein-tyrosine phosphatase PTPD1 regulates focal adhesion kinase autophosphorylation and cell migration
-
Carlucci A, Gedressi C, Lignitto L, Nezi L, Villa-Moruzzi E, Avvedimento EV, Gottesman M, Garbi C, Feliciello A. Protein-tyrosine phosphatase PTPD1 regulates focal adhesion kinase autophosphorylation and cell migration. J Biol Chem 283: 10919-10929, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 10919-10929
-
-
Carlucci, A.1
Gedressi, C.2
Lignitto, L.3
Nezi, L.4
Villa-Moruzzi, E.5
Avvedimento, E.V.6
Gottesman, M.7
Garbi, C.8
Feliciello, A.9
-
8
-
-
0037780966
-
Reactive oxygen species as essential mediators of cell adhesion: The oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion
-
Chiarugi P, Pani G, Giannoni E, Taddei L, Colavitti R, Raugei G, Symons M, Borrello S, Galeotti T, Ramponi G. Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion. J Cell Biol 161: 933-944, 2003.
-
(2003)
J Cell Biol
, vol.161
, pp. 933-944
-
-
Chiarugi, P.1
Pani, G.2
Giannoni, E.3
Taddei, L.4
Colavitti, R.5
Raugei, G.6
Symons, M.7
Borrello, S.8
Galeotti, T.9
Ramponi, G.10
-
9
-
-
77953769774
-
Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis
-
Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem 285: 20202-20212, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 20202-20212
-
-
Flier, S.N.1
Tanjore, H.2
Kokkotou, E.G.3
Sugimoto, H.4
Zeisberg, M.5
Kalluri, R.6
-
10
-
-
78049361778
-
Mechanical integration of actin and adhesion dynamics in cell migration
-
Gardel ML, Schneider IC, Aratyn-Schaus Y, Waterman CM. Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol 26: 315-333, 2010.
-
(2010)
Annu Rev Cell Dev Biol
, vol.26
, pp. 315-333
-
-
Gardel, M.L.1
Schneider, I.C.2
Aratyn-Schaus, Y.3
Waterman, C.M.4
-
11
-
-
80051507729
-
From intestinal stem cells to inflammatory bowel diseases
-
Gersemann M, Stange EF, Wehkamp J. From intestinal stem cells to inflammatory bowel diseases. World J Gastroenterol 17: 3198-3203, 2011.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 3198-3203
-
-
Gersemann, M.1
Stange, E.F.2
Wehkamp, J.3
-
12
-
-
0036624989
-
Neutrophil activation by heme: Implications for inflammatory processes
-
Graca-Souza AV, Arruda MA, de Freitas MS, Barja-Fidalgo C, Oliveira PL. Neutrophil activation by heme: implications for inflammatory processes. Blood 99: 4160-4165, 2002.
-
(2002)
Blood
, vol.99
, pp. 4160-4165
-
-
Graca-Souza, A.V.1
Arruda, M.A.2
de Freitas, M.S.3
Barja-Fidalgo, C.4
Oliveira, P.L.5
-
13
-
-
55049110418
-
No longer an innocent bystander: Epithelial toll-like receptor signaling in the development of mucosal inflammation
-
Gribar SC, Richardson WM, Sodhi CP, Hackam DJ. No longer an innocent bystander: epithelial toll-like receptor signaling in the development of mucosal inflammation. Mol Med 14: 645-659, 2008.
-
(2008)
Mol Med
, vol.14
, pp. 645-659
-
-
Gribar, S.C.1
Richardson, W.M.2
Sodhi, C.P.3
Hackam, D.J.4
-
14
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
Grivennikov S, Karin E, Terzic J, Mucida D, Yu GY, Vallabhapurapu S, Scheller J, Rose-John S, Cheroutre H, Eckmann L, Karin M. IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer. Cancer Cell 15: 103-113, 2009.
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
Scheller, J.7
Rose-John, S.8
Cheroutre, H.9
Eckmann, L.10
Karin, M.11
-
15
-
-
37849018402
-
Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB
-
Hasan RN, Schafer AI. Hemin upregulates Egr-1 expression in vascular smooth muscle cells via reactive oxygen species ERK-1/2-Elk-1 and NF-kappaB. Circ Res 102: 42-50, 2008.
-
(2008)
Circ Res
, vol.102
, pp. 42-50
-
-
Hasan, R.N.1
Schafer, A.I.2
-
16
-
-
79952026736
-
NADPH oxidase-mediated redox signaling: Roles in cellular stress response, stress tolerance, and tissue repair
-
Jiang F, Zhang Y, Dusting GJ. NADPH oxidase-mediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair. Pharmacol Rev 63: 218-242, 2011.
-
(2011)
Pharmacol Rev
, vol.63
, pp. 218-242
-
-
Jiang, F.1
Zhang, Y.2
Dusting, G.J.3
-
17
-
-
56849115896
-
FAK expression regulation and therapeutic potential
-
Li S, Hua ZC. FAK expression regulation and therapeutic potential. Adv Cancer Res 101: 45-61, 2008.
-
(2008)
Adv Cancer Res
, vol.101
, pp. 45-61
-
-
Li, S.1
Hua, Z.C.2
-
18
-
-
77954542760
-
REDOX regulation of IL-13 signaling in intestinal epithelial cells: Usage of alternate pathways mediates distinct gene expression patterns
-
Mandal D, Fu P, Levine AD. REDOX regulation of IL-13 signaling in intestinal epithelial cells: usage of alternate pathways mediates distinct gene expression patterns. Cell Signal 22: 1485-1494, 2010.
-
(2010)
Cell Signal
, vol.22
, pp. 1485-1494
-
-
Mandal, D.1
Fu, P.2
Levine, A.D.3
-
19
-
-
0027226245
-
Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6
-
McGee DW, Beagley KW, Aicher WK, McGhee JR. Transforming growth factor-beta and IL-1 beta act in synergy to enhance IL-6 secretion by the intestinal epithelial cell line, IEC-6. J Immunol 151: 970-978, 1993.
-
(1993)
J Immunol
, vol.151
, pp. 970-978
-
-
McGee, D.W.1
Beagley, K.W.2
Aicher, W.K.3
McGhee, J.R.4
-
20
-
-
0026802580
-
Transforming growth factor-beta enhances interleukin-6 secretion by intestinal epithelial cells
-
McGee DW, Beagley KW, Aicher WK, McGhee JR. Transforming growth factor-beta enhances interleukin-6 secretion by intestinal epithelial cells. Immunology 77: 7-12, 1992.
-
(1992)
Immunology
, vol.77
, pp. 7-12
-
-
McGee, D.W.1
Beagley, K.W.2
Aicher, W.K.3
McGhee, J.R.4
-
21
-
-
84866546199
-
Heme modulates smooth muscle cell proliferation and migration via NADPH oxidase: A counter-regulatory role for heme oxygenase system
-
Moraes JA, Barcellos-de-Souza P., Rodrigues G., Nascimento-Silva V., Silva SV, Assreuy J, Arruda MA, Barja-Fidalgo C. Heme modulates smooth muscle cell proliferation and migration via NADPH oxidase: a counter-regulatory role for heme oxygenase system. Atherosclerosis 224: 394-400, 2012.
-
(2012)
Atherosclerosis
, vol.224
, pp. 394-400
-
-
Moraes, J.A.1
Barcellos-de-Souza, P.2
Rodrigues, G.3
Nascimento-Silva, V.4
Silva, S.V.5
Assreuy, J.6
Arruda, M.A.7
Barja-Fidalgo, C.8
-
22
-
-
33746906722
-
Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility
-
Oates PS, West AR. Heme in intestinal epithelial cell turnover, differentiation, detoxification, inflammation, carcinogenesis, absorption and motility. World J Gastroenterol 12: 4281-4295, 2006.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 4281-4295
-
-
Oates, P.S.1
West, A.R.2
-
23
-
-
3242754353
-
The role of RBC destruction in vascular regions with high turbulence on atherosclerosis
-
Olgun A, Akman S, Erbil MK. The role of RBC destruction in vascular regions with high turbulence on atherosclerosis. Med Hypotheses 63: 283-284, 2004.
-
(2004)
Med Hypotheses
, vol.63
, pp. 283-284
-
-
Olgun, A.1
Akman, S.2
Erbil, M.K.3
-
24
-
-
80051980558
-
FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing
-
Owen KA, Abshire MY, Tilghman RW, Casanova JE, Bouton AH. FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing. PLos One 6: e23123, 2011.
-
(2011)
PLos One
, vol.6
-
-
Owen, K.A.1
Abshire, M.Y.2
Tilghman, R.W.3
Casanova, J.E.4
Bouton, A.H.5
-
25
-
-
0142185379
-
Meat and cancer: Haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats
-
Pierre F, Tache S, Petit CR, Van der Meer R, Corpet DE. Meat and cancer: haemoglobin and haemin in a low-calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats. Carcinogenesis 24: 1683-1690, 2003.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1683-1690
-
-
Pierre, F.1
Tache, S.2
Petit, C.R.3
Van der Meer, R.4
Corpet, D.E.5
-
26
-
-
78650869592
-
Mitochondrial ROS generation and its regulation: Mechanisms involved in H(2)O(2) signaling
-
Rigoulet M, Yoboue ED, Devin A. Mitochondrial ROS generation and its regulation: mechanisms involved in H(2)O(2) signaling. Antioxid Redox Signal 14: 459-468, 2011.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 459-468
-
-
Rigoulet, M.1
Yoboue, E.D.2
Devin, A.3
-
27
-
-
55149113944
-
Welcome to the neighborhood: Epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites
-
Saenz SA, Taylor BC, Artis D. Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites. Immunol Rev 226: 172-190, 2008.
-
(2008)
Immunol Rev
, vol.226
, pp. 172-190
-
-
Saenz, S.A.1
Taylor, B.C.2
Artis, D.3
-
28
-
-
77949772131
-
Isoform specific functions of Nox protein-derived reactive oxygen species in the vasculature
-
Schroder K. Isoform specific functions of Nox protein-derived reactive oxygen species in the vasculature. Curr Opin Pharmacol 10: 122-126, 2010.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 122-126
-
-
Schroder, K.1
-
29
-
-
84155184582
-
Mucins in inflammatory bowel diseases and colorectal cancer
-
Sheng YH, Hasnain SZ, Florin TH, McGuckin MA. Mucins in inflammatory bowel diseases and colorectal cancer. J Gastroenterol Hepatol 27: 28-38, 2012.
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 28-38
-
-
Sheng, Y.H.1
Hasnain, S.Z.2
Florin, T.H.3
McGuckin, M.A.4
-
30
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC. Measurement of protein using bicinchoninic acid. Anal Biochem 150: 76-85, 1985.
-
(1985)
Anal Biochem
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
31
-
-
33847381116
-
The fundamental basis of inflammatory bowel disease
-
Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 117: 514-521, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 514-521
-
-
Strober, W.1
Fuss, I.2
Mannon, P.3
-
32
-
-
79957670765
-
Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases
-
Swanson PA, Kumar A 2nd, Samarin S, Vijay-Kumar M, Kundu K, Murthy N, Hansen J, Nusrat A, Neish AS. Enteric commensal bacteria potentiate epithelial restitution via reactive oxygen species-mediated inactivation of focal adhesion kinase phosphatases. Proc Natl Acad Sci USA 108: 8803-8808, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 8803-8808
-
-
Swanson, P.A.1
Kumar, A.2
Samarin, S.3
Vijay-Kumar, M.4
Kundu, K.5
Murthy, N.6
Hansen, J.7
Nusrat, A.8
Neish, A.S.9
-
33
-
-
65349157681
-
Compartmentalization of redox signaling through NADPH oxidase-derived ROS
-
Ushio-Fukai M. Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Tedox Signal 11: 1289-1299, 2009.
-
(2009)
Antioxid Tedox Signal
, vol.11
, pp. 1289-1299
-
-
Ushio-Fukai, M.1
-
34
-
-
0035885926
-
Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase
-
Wagener FA, Eggert A, Boerman OC, Oyen WJ, Verhofstad A, Abraham NG, Adema G, van Kooyk Y, de Witte T, Figdor CG. Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase. Blood 98: 1802-1811, 2001.
-
(2001)
Blood
, vol.98
, pp. 1802-1811
-
-
Wagener, F.A.1
Eggert, A.2
Boerman, O.C.3
Oyen, W.J.4
Verhofstad, A.5
Abraham, N.G.6
Adema, G.7
van Kooyk, Y.8
de Witte, T.9
Figdor, C.G.10
-
35
-
-
0041967387
-
Different faces of the heme-heme oxygenase system in inflammation
-
Wagener FA, Volk HD, Willis D, Abraham NG, Soares MP, Adema GJ, Figdor CG. Different faces of the heme-heme oxygenase system in inflammation. Pharmacol Rev 55: 551-571, 2003.
-
(2003)
Pharmacol Rev
, vol.55
, pp. 551-571
-
-
Wagener, F.A.1
Volk, H.D.2
Willis, D.3
Abraham, N.G.4
Soares, M.P.5
Adema, G.J.6
Figdor, C.G.7
-
36
-
-
64549129621
-
Hemin promotes proliferation and differentiation of endothelial progenitor cells via activation of AKT and ERK
-
Wang JY, Lee YT, Chang PF, Chau LY. Hemin promotes proliferation and differentiation of endothelial progenitor cells via activation of AKT and ERK. J Cell Physiol 219: 617-625, 2009.
-
(2009)
J Cell Physiol
, vol.219
, pp. 617-625
-
-
Wang, J.Y.1
Lee, Y.T.2
Chang, P.F.3
Chau, L.Y.4
-
37
-
-
34547672619
-
Intestinal epithelial cell signalling and chronic inflammation: From the proteome to specific molecular mechanisms
-
Werner T, Haller D. Intestinal epithelial cell signalling and chronic inflammation: From the proteome to specific molecular mechanisms. Mutat Res 622: 42-57, 2007.
-
(2007)
Mutat Res
, vol.622
, pp. 42-57
-
-
Werner, T.1
Haller, D.2
-
38
-
-
0024767010
-
Haem in the gut I Fate of haemoproteins and the absorption of haem
-
Young GP, Rose IS, St John DJ. Haem in the gut I Fate of haemoproteins and the absorption of haem. J Gastroenterol Hepatol 4: 537-545, 1989.
-
(1989)
J Gastroenterol Hepatol
, vol.4
, pp. 537-545
-
-
Young, G.P.1
Rose, I.S.2
John St, D.J.3
|