Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: Design, optimization and evaluation

International Journal of Biological Macromolecules

Volumn 54, Issue 1, 2013, Pages 144-154

  Nayak, Amit Kumar ^a   Pal, Dilipkumar ^b   Pradhan, Jyotiprakash ^a   Hasnain, M Saquib ^a  

^a SEEMANTA INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

^b GURU GHASIDAS UNIVERSITY   (India)

Author keywords

Alginate; Controlled drug release; Factorial design; Fenugreek seed mucilage; Metformin HCl; Mucoadhesion; Trigonella foenum graecum L.

Indexed keywords

ALGINIC ACID; CALCIUM CHLORIDE; METFORMIN;

ALLOXAN DIABETES MELLITUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DEGRADATION; DRUG DESIGN; DRUG DOSAGE FORM COMPARISON; DRUG ENCAPSULATION EFFICIENCY; DRUG RELEASE; ENCAPSULATION; FENUGREEK; GELATION; IN VITRO STUDY; INFRARED SPECTROSCOPY; MALE; MUCILAGE; MUCOADHESIVITY; NONHUMAN; PARTICLE SIZE; PH; PHARMACOLOGICAL PARAMETERS; PLANT SEED; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SCANNING ELECTRON MICROSCOPY;

RATTUS; TRIGONELLA FOENUM-GRAECUM;

EID: 84872367575     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2012.12.008     Document Type: Article

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