Development of a new nasal drug delivery system of diazepam with natural mucoadhesive agent from Trigonella foenum-graecum L

Journal of Scientific and Industrial Research

Volumn 64, Issue 12, 2005, Pages 973-977

  Datta, Rimi ^a   Bandyopadhyay, A K ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

Diazepam; Nasal drug; Synthetic polymers

Indexed keywords

PHARMACEUTICAL INDUSTRY;

BOVINAE; TRIGONELLA FOENUM GRAECUM;

EID: 29244456429     PISSN: 00224456     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Nakamura K, Maitani Y, Lowman A M, Takayama K, Peppas N A & Nagai T, Uptake and release of budesonide from mucoadhesive, pH sensitive copolymers and their application to nasal delivery, J Control Rel, 61 (1999) 329-335.
2. Lee C P, de Vrueh R L A & Smith P L, Selection of development candidates based on in vitro permeability measurements, Adv Drug Del Rev, 23 (1997) 47-62.
3. Jorgensen L & Bechgaard E, Intranasal permeation of thyrotropin releasing hormone: In vitro study of permeation and enzymatic degradation, Int J Pharm, 107 (1994) 231-237.
4. Kubo H, Hosoya K I, Natsume H, Sugibayashi K & Morimoto Y, In vitro permeation of several model drugs across rabbit nasal mucosa, Int J Pharm, 103 (1994) 27-36.
5. Wheatley M A, Dent J, Wheeldon E B & Smith P L, Nasal drug delivery: an in vitro characterization of transepithelial electrical properties and fluxes in the presence or absence of enhancers, J Control Rel, 8 (1988) 167-177.
6. Hosoya K I, Kubo H, Natsume H, Sugibayashi K, Morimoto Y & Yamashita S, The structural barrier of absorptive mucosae: site difference of the permeability of fluoroscein isothiocyanate-labelled dextran in rabbits, Biopharm Drug Disp, 14 (1993) 685-696.
7. Khullar P, Khar R K & Agarwal S P, Evaluation of guar gum in the preparation of sustained-release matrix tablets, Drug Dev Ind Pharm, 24 (1998) 1095-1099.
8. Rao P S & Srivastava H C, Tamarind, in Industrial Gums, 2nd edn, edited by R L Whistler (Academic Press, New York) 1973, 369-411.
9. Rao Y M, Vani G & Bala Ramesha Chary R, Design and evaluation of mucoadhesive drug delivery systems, Indian Drugs, 35 (1998) 558-565.
10. Park K & Robinson R, Bioadhesive platforms for oral-controlled drug delivery: method to study bioadhesion, Int J Pharm, 19 (1984) 107-127.
11. Schmidt M C, Simmen D, Hilbe M, Boderke P, Ditzinger G N, Sandow J R, Lang S, Rubas W & Merkle H P, Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium, J Pharm Sci, 89 (2000) 396-407.
12. Frantz S W, Instrumentation and methodology for in vitro skin diffusion cells in methodology for skin absorption, in Methods for Skin Absorption (CRC Press, Florida) 1990, 35-59.