Engineering a soluble high-affinity receptor domain that neutralizes staphylococcal enterotoxin C in rabbit models of disease

Protein Engineering, Design and Selection

Volumn 26, Issue 2, 2013, Pages 133-142

  Mattis, D M ^a   Spaulding, A R ^b,d   Chuang Smith, O N ^b   Sundberg, E J ^c,e   Schlievert, P M ^b,d   Kranz, D M ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF IOWA   (United States)

^e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

directed evolution; staphylococcal enterotoxin B (SEB); staphylococcal enterotoxin C (SEC); yeast display

Indexed keywords

CYTOKINES; DIRECTED EVOLUTION; ENTEROTOXIN; EXTRACELLULAR; IN-VITRO; INFECTIVE ENDOCARDITIS; INFLAMMATORY REACTION; NEUTRALIZING AGENTS; RABBIT MODELS; RECEPTOR DOMAINS; STAPHYLOCOCCAL ENTEROTOXIN B; STAPHYLOCOCCUS AUREUS; T CELLS; T-CELL RECEPTORS; TOXIC SHOCKS; VARIABLE DOMAIN; YEAST DISPLAY;

BACTERIA; CELL MEMBRANES; MODELS; PROTEINS; YEAST;

C (PROGRAMMING LANGUAGE);

ANTIBIOTIC AGENT; STAPHYLOCOCCUS ENTEROTOXIN B; STAPHYLOCOCCUS ENTEROTOXIN C; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG; VB L3;

ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIAL LOAD; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS REACTION; DIRECTED MOLECULAR EVOLUTION; DRUG EFFICACY; EXPERIMENTAL RABBIT; IN VITRO STUDY; IN VIVO STUDY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MORBIDITY; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ENGINEERING; PROTEIN PURIFICATION; T LYMPHOCYTE; TREATMENT DURATION; YEAST;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL LINE; CELL SURFACE DISPLAY TECHNIQUES; DIRECTED MOLECULAR EVOLUTION; DISEASE MODELS, ANIMAL; ENDOCARDITIS, BACTERIAL; ENTEROTOXINS; HUMANS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PNEUMONIA, STAPHYLOCOCCAL; PROTEIN BINDING; PROTEIN ENGINEERING; RABBITS; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECOMBINANT PROTEINS; STAPHYLOCOCCAL INFECTIONS; SUPERANTIGENS; T-LYMPHOCYTES;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; ORYCTOLAGUS CUNICULUS; STAPHYLOCOCCUS AUREUS;

EID: 84872358383     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzs094     Document Type: Article

References (44)

1. Bachert,C., Gevaert,P., Zhang,N., van Zele,T. and Perez-Novo,C. (2007 Chem. Immunol. Allergy, 93, 214-236
2. Boder,E.T. and Wittrup,K.D. (2000) Methods Enzymol., 328, 430-444
3. Bohach,G.A., Fast,D.J., Nelson,R.D. and Schlievert,P.M. (1990) Crit. Rev. Microbiol., 17, 251-272
4. Bonsor,D.A., Postel,S., Pierce,B.G., Wang,N., Zhu,P., Buonpane,R.A., Weng,Z., Kranz,D.M. and Sundberg,E.J. (2011) J. Mol. Biol., 411, 321-328
5. Buonpane,R.A., Churchill,H.R., Moza,B., Sundberg,E.J., Peterson,M.L., Schlievert,P.M. and Kranz,D.M. (2007) Nat. Med., 13, 725-729
6. Campbell,S.J., Deshmukh,H.S., Nelson,C.L., et al. (2008) J. Clin. Microbiol., 46, 678-684
7. Cho,S., Swaminathan,C.P., Yang,J., Kerzic,M.C., Guan,R., Kieke,M.C., Kranz,D.M., Mariuzza,R.A. and Sundberg,E.J. (2005) Structure, 13, 1775-1787
8. Churchill,H.R., Andersen,P.S., Parke,E.A., Mariuzza,R.A. and Kranz,D.M. (2000) J. Exp. Med., 191, 835-846
9. Derzelle,S., Dilasser,F., Duquenne,M. and Deperrois,V. (2009) Food Microbiol., 26, 896-904
10. DeVries,A.S., Lesher,L., Schlievert,P.M., Rogers,T., Villaume,L.G., Danila,R. and Lynfield,R. (2011) PLoS One, 6, e22997
11. Dinges,M.M. and Schlievert,P.M. (2001) Infect. Immun., 69, 7169-7172
12. Fey,P.D., Said-Salim,B., Rupp,M.E., Hinrichs,S.H., Boxrud,D.J., Davis,C.C., Kreiswirth,B.N. and Schlievert,P.M. (2003) Antimicrob. Agents Chemother., 47, 196-203
13. Fowler,V.G., Jr., Miro,J.M., Hoen,B., et al. (2005) J. Am. Med. Assoc., 293, 3012-3021
14. Fraser,J.D. and Proft,T. (2008) Immunol. Rev., 225, 226-243
15. Holler,P.D. and Kranz,D.M. (2003) Immunity, 18, 255-264
16. John,C.C., Niermann,M., Sharon,B., Peterson,M.L., Kranz,D.M. and Schlievert,P.M. (2009) Clin. Infect. Dis., 49, 1893-1896
17. Kieke,M.C., Sundberg,E., Shusta,E.V., Mariuzza,R.A., Wittrup,K.D. and Kranz,D.M. (2001) J. Mol. Biol., 307, 1305-1315
18. Kos,V.N., Desjardins,C.A., Griggs,A., et al. (2012) MBio, 3(3):e00112-12. doi:10.1128/mBio.00112-12
19. Lalani,T., Federspiel,J.J., Boucher,H.W., et al. (2008) J. Clin. Microbiol., 46, 2890-2896
20. Leung,D.Y., Meissner,H.C., Shulman,S.T., et al. (2002) J. Pediatr., 140, 742-746
21. Li,H., Llera,A., Malchiodi,E.L. and Mariuzza,R.A. (1999) Annu. Rev. Immunol., 17, 435-466
22. Lowy,F.D. (1998) N. Engl. J. Med., 339, 520-532
23. Luppi,P., Rudert,W.A., Zanone,M.M., et al. (1998) Circulation, 98, 777-785
24. Macias,E.S., Pereira,F.A., Rietkerk,W. and Safai,B. (2011) J. Am. Acad. Dermatol., 64, 455-472; quiz 473-454
25. Marrack,P. and Kappler,J. (1990) Science, 248, 705-711
26. McCormick,J.K., Yarwood,J.M. and Schlievert,P.M. (2001) Annu. Rev. Microbiol., 55, 77-104
27. Mertz,P.M., Cardenas,T.C., Snyder,R.V., Kinney,M.A., Davis,S.C. and Plano,L.R. (2007) Arch. Dermatol., 143, 1259-1263
28. Moza,B., Buonpane,R.A., Zhu,P., Herfst,C.A., Rahman,A.K., McCormick,J.K., Kranz,D.M. and Sundberg,E.J. (2006) Proc. Natl Acad. Sci. USA, 103, 9867-9872
29. Nienaber,J.J., Sharma Kuinkel,B.K., Clarke-Pearson,M., et al. (2011) J. Infect. Dis., 204, 704-713
30. Papageorgiou,A.C. and Acharya,K.R. (1997) Structure, 5, 991-996
31. Parsonnet,J., Gillis,Z.A., Richter,A.G. and Pier,G.B. (1987) Infect. Immun., 55, 1070-1076
32. Pragman,A.A., Yarwood,J.M., Tripp,T.J. and Schlievert,P.M. (2004) J. Bacteriol., 186, 2430-2438
33. Resch,A., Wilke,M. and Fink,C. (2009) Eur. J. Health Econ., 10, 287-297
34. Robert,J., Tristan,A., Cavalie,L., Decousser,J.W., Bes,M., Etienne,J. and Laurent,F. (2011) Antimicrob. Agents Chemother., 55, 734- 739
35. Sacar,M., Sacar,S., Cevahir,N., et al. (2010) Tex. Heart Inst. J., 37, 400-404
36. Schlievert,P.M. (1982) Infect. Immun., 36, 123-128
37. Schlievert,P.M., Case,L.C., Nemeth,K.A., et al. (2007) Biochemistry, 46, 14349-14358
38. Schlievert,P.M., Case,L.C., Strandberg,K.L., Abrams,B.B. and Leung,D.Y. (2008) Clin. Infect. Dis., 46, 1562-1567
39. Schlievert,P.M., Gahr,P.J., Assimacopoulos,A.P., Dinges,M.M., Stoehr,J.A., Harmala,J.W., Hirt,H. and Dunny,G.M. (1998) Infect. Immun., 66, 218-223
40. Sharma-Kuinkel,B.K., Ahn,S.H., Rude,T.H., et al. (2011) J. Clin. Microbiol., 50, 848-856
41. Shilo,N. and Quach,C. (2011) Paediatr. Respir. Rev., 12, 182-189
42. Strandberg,K.L., Rotschafer,J.H., Vetter,S.M., Buonpane,R.A., Kranz,D.M. and Schlievert,P.M. (2010) J. Infect. Dis., 202, 1690- 697
43. Wang,N., Mattis,D.M., Sundberg,E.J., Schlievert,P.M. and Kranz,D.M. (2010) Clin. Vaccine Immunol., 17, 1781-1789
44. Xiong,Y.Q., Fowler,V.G., Yeaman,M.R., Perdreau-Remington,F., Kreiswirth,B.N. and Bayer,A.S. (2009) J. Infect. Dis., 199, 201- 08