Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections

Journal of Clinical Microbiology

Volumn 46, Issue 2, 2008, Pages 678-684

  Campbell, Steven J ^a   Deshmukh, Hitesh S ^a   Nelson, Charlotte L ^b   Bae, In Gyu ^a,d   Stryjewski, Martin E ^b   Federspiel, Jerome J ^a   Tonthat, Giang T ^a   Rude, Thomas H ^a   Barriere, Steven L ^c   Corey, Ralph ^a,b   Fowler Jr , Vance G ^a,b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^c THERAVANCE INC   (United States)

^d Gyeongsang National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CLOXACILLIN; METICILLIN; NAFCILLIN; OXACILLIN; TELAVANCIN; VANCOMYCIN;

ADULT; AGR GENE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ETA GENE; ETB GENE; FEMALE; FNBB GENE; GENE CASSETTE; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTICENTER STUDY; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; PVL GENE; SDRC GENE; SDRD GENE; SDRE GENE; SEA GENE; SED GENE; SEE GENE; SEG GENE; SEJ GENE; SKIN INFECTION; SOUTH AFRICA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; TST GENE; UNITED STATES; V8 GENE;

ADULT; AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DNA FINGERPRINTING; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EPIDEMIOLOGY, MOLECULAR; FEMALE; GENOTYPE; HUMANS; MALE; METHICILLIN RESISTANCE; MIDDLE AGED; SOUTH AFRICA; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS; TRANS-ACTIVATORS; TREATMENT OUTCOME; UNITED STATES; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 38949112113     PISSN: 00951137     EISSN: None     Source Type: Journal    
DOI: 10.1128/JCM.01822-07     Document Type: Article

References (35)

1. Adem, P. V., C. P. Montgomery, A. N. Husain, T. K. Koogler, V. Arangelovich, M. Humilier, S. Boyle-Vavra, and R. S. Daum. 2005. Staphylococcus aureus sepsis and the Waterhouse-Friderichsen syndrome in children. N. Engl. J. Med. 353:1245-1251.
2. Baba, T., F. Takeuchi, M. Kuroda, H. Yuzawa, K. Aoki, A. Oguchi, Y. Nagai, N. Iwama, K. Asano, T. Naimi, H. Kuroda, L. Cui, K. Yamamoto, and K. Hiramatsu. 2002. Genome and virulence determinants of high virulence community-acquired MRSA. Lancet 359:1819-1827.
3. Bhattacharya, D., H. Carleton, C. J. Tsai, E. J. Baron, and F. Perdreau-Remington. 2007. Differences in clinical and molecular characteristics of skin and soft tissue methicillin-resistant Staphylococcus aureus isolates between two hospitals in Northern California. J. Clin. Microbiol. 45:1798-1803.
4. Corey, G. R., M. E. Stryjewski, W. D. O'Riordan, V. G. Fowler, Jr., A. Hopkins, M. M. Kitt, and S. L. Barriere. The ATLAS studies: double-blind, randomised, active controlled, multinational phase 3 trials comparing telavancin with vancomycin for the treatment of complicated skin and skin structure infections, abstr. 1733_342. Abstr. 17th Eur. Cong. Clin. Microbiol. Infect. Dis., Munich, Germany, 31 March to 4 April 2007.
5. Cribier, B., G. Prevost, P. Couppie, V. Finck-Barbancon, E. Grosshans, and Y. Piemont. 1992. Staphylococcus aureus leukocidin: a new virulence factor in cutaneous infections? An epidemiological and experimental study. Dermatology 185:175-180.
6. Crum, N. F., R. U. Lee, S. A. Thornton, O. C. Stine, M. R. Wallace, C. Barrozo, A. Keefer-Norris, S. Judd, and K. L. Russell. 2006. Fifteen-year study of the changing epidemiology of methicillin-resistant Staphylococcus aureus. Am. J. Med. 119:943-951.
7. Daum, R. S. 2007. Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. N. Engl. J. Med. 357:380-390.
8. Diekema, D. J., M. A. Pfaller, F. J. Schmitz, J. Smayevsky, J. Bell, R. N. Jones, and M. Beach. 2001. Survey of infections due to Staphylococcus species: frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999. Clin. Infect. Dis. 32(Suppl. 2):S114-S132.
9. Diep, B. A., S. R. Gill, R. F. Chang, T. H. Phan, J. H. Chen, M. G. Davidson, F. Lin, J. Lin, H. A. Carleton, E. F. Mongodin, G. F. Sensabaugh, and F. Perdreau-Remington. 2006. Complete genome sequence of USA300, an epidemic clone of community-acquired methicillin-resistant Staphylococcus aureus. Lancet 367:731-739.
10. Fowler, V. G., Jr., J. M. Miro, B. Hoen, C. H. Cabell, E. Abrutyn, E. Rubinstein, G. R. Corey, D. Spelman, S. F. Bradley, B. Barsic, P. A. Pappas, K. J. Anstrom, D. Wray, C. Q. Fortes, I. Anguera, E. Athan, P. Jones, J. T. van der Meer, T. S. Elliott, D. P. Levine, and A. S. Bayer. 2005. Staphylococcus aureus endocarditis: a consequence of medical progress. JAMA 293: 3012-3021.
11. Fowler, V. G., Jr., C. L. Nelson, L. M. McIntyre, B. N. Kreiswirth, A. Monk, G. L. Archer, J. Federspiel, S. Naidich, B. Remortel, T. Rude, P. Brown, L. B. Reller, G. R. Corey, and S. R. Gill. 2007. Potential associations between hematogenous complications and bacterial genotype in Staphylococcus aureus Infection. J. Infect. Dis. 196:738-747.
12. Fridkin, S. K., J. C. Hageman, M. Morrison, L. T. Sanza, K. Como-Sabetti, J. A. Jernigan, K. Harriman, L. H. Harrison, R. Lynfield, and M. M. Farley. 2005. Methicillin-resistant Staphylococcus aureus disease in three communities. N. Engl. J. Med. 352:1436-1444.
13. Grundmann, H., S. Hori, and G. Tanner. 2001. Determining confidence intervals when measuring genetic diversity and the discriminatory abilities of typing methods for microorganisms. J. Clin. Microbiol. 39:4190-4192.
14. King, M. D., B. J. Humphrey, Y. F. Wang, E. V. Kourbatova, S. M. Ray, and H. M. Blumberg. 2006. Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections. Ann. Intern. Med. 144:309-317.
15. Labandeira-Rey, M., F. Couzon, S. Boisset, E. L. Brown, M. Bes, Y. Benito, E. M. Barbu, V. Vazquez, M. Hook, J. Etienne, F. Vandenesch, and M. G. Bowden. 2007. Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science 315:1130-1133.
16. Lee, M. C., A. M. Rios, M. F. Aten, A. Mejias, D. Cavuoti, G. H. McCracken, Jr., and R. D. Hardy. 2004. Management and outcome of children with skin and soft tissue abscesses caused by community-acquired methicillin-resistant Staphylococcus aureus. Pediatr. Infect. Dis. J. 23:123-127.
17. Lina, G., Y. Piemont, F. Godail-Gamot, M. Bes, M. O. Peter, V. Gauduchon, F. Vandenesch, and J. Etienne. 1999. Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin. Infect. Dis. 29:1128-1132.
18. Lo, W. T., W. J. Lin, M. H. Tseng, S. R. Wang, M. L. Chu, and C. C. Wang. 2006. Methicillin-resistant Staphylococcus aureus in children, Taiwan. Emerg. Infect. Dis. 12:1267-1270.
19. McDougal, L. K., C. D. Steward, G. E. Killgore, J. M. Chaitram, S. K. McAllister, and F. C. Tenover. 2003. Pulsed-field gel electrophoresis typing of oxacillin-resistant Staphylococcus aureus isolates from the United States: establishing a national database. J. Clin. Microbiol. 41:5113-5120.
20. Miller, L. G., F. Perdreau-Remington, A. S. Bayer, B. Diep, N. Tan, K. Bharadwa, J. Tsui, J. Perlroth, A. Shay, G. Tagudar, U. Ibebuogu, and B. Spellberg. 2007. Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin-susceptible S. aureus infection: a prospective investigation. Clin. Infect. Dis. 44:471-482.
21. Moran, G. J., A. Krishnadasan, R. J. Gorwitz, G. E. Fosheim, L. K. McDougal, R. B. Carey, and D. A. Talan. 2006. Methicillin-resistant S. aureus infections among patients in the emergency department. N. Engl. J. Med. 355:666-674.
22. Naimi, T. S., K. H. LeDell, K. Como-Sabetti, S. M. Borchardt, D. J. Boxrud, J. Etienne, S. K. Johnson, F. Vandenesch, S. Fridkin, C. O'Boyle, R. N. Danila, and R. Lynfield. 2003. Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection. JAMA 290: 2976-2984.
23. Novick, R. P., and A. Subedi. 2007. The SaPIs: mobile pathogenicity islands of Staphylococcus. Chem. Immunol. Allergy 93:42-57.
24. Okuma, K., K. Iwakawa, J. D. Turnidge, W. B. Grubb, J. M. Bell, F. G. O'Brien, G. W. Coombs, J. W. Pearman, F. C. Tenover, M. Kapi, C. Tiensasitorn, T. Ito, and K. Hiramatsu. 2002. Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community. J. Clin. Microbiol. 40:4289-4294.
25. Oliveira, D. C., and H. de Lencastre. 2002. Multiplex PCR strategy for rapid identification of structural types and variants of the mec element in methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 46: 2155-2161.
26. Peacock, S. J., C. E. Moore, A. Justice, M. Kantzanou, L. Story, K. Mackie, G. O'Neill, and N. P. Day. 2002. Virulent combinations of adhesin and toxin genes in natural populations of Staphylococcus aureus. Infect. Immun. 70: 4987-4996.
27. Reiner, A., D. Yekutieli, and Y. Benjamini. 2003. Identifying differentially expressed genes using false discovery rate controlling procedures. Bioinformatics 19:368-375.
28. Robinson, D. A., and M. C. Enright. 2004. Evolution of Staphylococcus aureus by large chromosomal replacements. J. Bacteriol. 186:1060-1064.
29. Simpson, E. H. 1949. Measurement of diversity. Nature 163:688.
30. Stryjewski, M. E., V. H. Chu, W. D. O'Riordan, B. L. Warren, L. M. Dunbar, D. M. Young, M. Vallee, V. G. Fowler, Jr., J. Morganroth, S. L. Barriere, M. M. Kitt, and G. R. Corey. 2006. Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study. Antimicrob. Agents Chemother. 50:862-867.
31. Vandenesch, F., T. Naimi, M. C. Enright, G. Lina, G. R. Nimmo, H. Heffernan, N. Liassine, M. Bes, T. Greenland, M. E. Reverdy, and J. Etienne. 2003. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg. Infect. Dis. 9:978-984.
32. Voyich, J. M., M. Otto, B. Mathema, K. R. Braughton, A. R. Whitney, D. Welty, R. D. Long, D. W. Dorward, D. J. Gardner, G. Lina, B. N. Kreiswirth, and F. R. DeLeo. 2006. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J. Infect. Dis. 194:1761-1770.
33. Xu, Y., J. M. Rivas, E. L. Brown, X. Liang, and M. Hook. 2004. Virulence potential of the staphylococcal adhesin CNA in experimental arthritis is determined by its affinity for collagen. J. Infect. Dis. 189:2323- 2333.
34. Yamasaki, O., J. Kaneko, S. Morizane, H. Akiyama, J. Arata, S. Narita, J. Chiba, Y. Kamio, and K. Iwatsuki. 2005. The association between Staphylococcus aureus strains carrying Panton-Valentine leukocidin genes and the development of deep-seated follicular infection. Clin. Infect. Dis. 40:381-385.
35. Zhang, K., J. A. McClure, S. Elsayed, T. Louie, and J. M. Conly. 2005. Novel multiplex PCR assay for characterization and concomitant subtyping of staphylococcal cassette chromosome mec types I to V in methicillin-resistant Staphylococcus aureus. J. Clin. Microbiol. 43:5026-5033.