Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity

Cell Death and Differentiation

Volumn 20, Issue 2, 2013, Pages 353-365

  Kushnareva, Y E ^a,d   Gerencser, A A ^a,e   Bossy, B ^a,b   Ju, W K ^a,f   White, A D ^c   Waggoner, J ^c   Ellisman, M H ^c   Perkins, G ^c   Bossy Wetzel, E ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^e BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

calcium; mitochondria; OPA1

Indexed keywords

GLUTAMIC ACID; GUANOSINE TRIPHOSPHATASE; HISTAMINE; MITOCHONDRIAL DNA; NICOTINAMIDE ADENINE DINUCLEOTIDE; OPTIC ATROPHY 1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOENERGY; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL MEMBRANE PERMEABILITY; CELL STRUCTURE; CELL ULTRASTRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOSOL; ELECTRON MICROSCOPY; EXCITOTOXICITY; GENE SILENCING; HELA CELL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NERVE CELL LESION; NUCLEOTIDE SEQUENCE; OXIDATION; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RETINA GANGLION CELL; SENSITIZATION;

APOPTOSIS; CALCIUM; DNA, MITOCHONDRIAL; GTP PHOSPHOHYDROLASES; HELA CELLS; HISTAMINE; HUMANS; MITOCHONDRIA; NAD; OPTIC ATROPHY, AUTOSOMAL DOMINANT; OXIDATION-REDUCTION; OXIDATIVE PHOSPHORYLATION; RETINAL GANGLION CELLS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84872356908     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2012.128     Document Type: Article

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