Metabolic pathway analysis and kinetic studies for production of nattokinase in Bacillus subtilis

Bioprocess and Biosystems Engineering

Volumn 36, Issue 1, 2013, Pages 45-56

  Unrean, Pornkamol ^a,b   Nguyen, Nhung H A ^a  

^a KING MONGKUT'S UNIVERSITY OF TECHNOLOGY THONBURI   (Thailand)

^b NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

Author keywords

Bacillus subtilis; Culture condition optimization; Elementary mode analysis; Metabolic network model; Nattokinase; Target gene for engineering

Indexed keywords

BACILLUS SUBTILIS; ELEMENTARY MODE; METABOLIC NETWORK; NATTOKINASE; TARGET GENES;

CELL CULTURE; CELL ENGINEERING; EXPERIMENTS; FORECASTING; GENES; METABOLISM; OPTIMIZATION; PRODUCT DESIGN; SYNTHESIS (CHEMICAL);

SUBSTRATES;

2,3 BUTANEDIOL; ACETIC ACID; ALCOHOL; BACTERIAL ENZYME; LACTIC ACID; NATTOKINASE; OXYGEN; SUCCINIC ACID; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BACILLUS SUBTILIS; BACTERIAL CELL; BACTERIAL STRAIN; BACTERIUM CULTURE; BATCH FERMENTATION; CELL METABOLISM; CONTROLLED STUDY; ELEMENTARY MODE ANALYSIS; ENZYME KINETICS; ENZYME SUBSTRATE; ENZYME SYNTHESIS; FEASIBILITY STUDY; GENE DELETION; GENE TARGETING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; WASTE MANAGEMENT;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; COMPUTER SIMULATION; KINETICS; METABOLIC CLEARANCE RATE; METABOLOME; MODELS, BIOLOGICAL; OXYGEN; SUBTILISINS;

BACILLUS SUBTILIS;

EID: 84872329288     PISSN: 16157591     EISSN: 16157605     Source Type: Journal    
DOI: 10.1007/s00449-012-0760-y     Document Type: Article

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