Long-term treatment of osteoporosis: Safety and efficacy appraisal of denosumab

Therapeutics and Clinical Risk Management

Volumn 8, Issue , 2012, Pages 295-306

  Anastasilakis, Athanasios D ^a   Toulis, Konstantinos A ^a   Polyzos, Stergios A ^b   Anastasilakis, Chrysostomos D ^a   Makras, Polyzois ^c  

^a 424 General Army Hospital   (Greece)

^b ARISTOTLE UNIVERSITY MEDICAL SCHOOL   (Greece)

^c IASO GENERAL HOSPITAL   (Greece)

Author keywords

Adverse event; Denosumab; Efficacy; Fracture; Osteoporosis; Safety

Indexed keywords

ALKALINE PHOSPHATASE; AMINO TERMINAL TELOPEPTIDE; BISPHOSPHONIC ACID DERIVATIVE; CARBOXY TERMINAL TELOPEPTIDE; DENOSUMAB; MONOCLONAL ANTIBODY; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PLACEBO; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

BONE DENSITY; BONE TURNOVER; COST EFFECTIVENESS ANALYSIS; DRUG ABSORPTION; DRUG EFFICACY; DRUG HALF LIFE; DRUG SAFETY; DRUG WITHDRAWAL; HIP FRACTURE; HUMAN; KIDNEY DYSFUNCTION; LONG TERM CARE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOPENIA; OSTEOPOROSIS; PHARMACODYNAMICS; POSTMENOPAUSE OSTEOPOROSIS; REGULATORY T LYMPHOCYTE; REVIEW; RISK REDUCTION; SINGLE DRUG DOSE; SPINE FRACTURE;

EID: 84872292524     PISSN: 11766336     EISSN: 1178203X     Source Type: Journal    
DOI: 10.2147/TCRM.S24239     Document Type: Review

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