TLR7 contributes to the rapid progression but not to the overall fatal outcome of secondary pneumococcal disease following influenza a virus infection

Journal of Innate Immunity

Volumn 5, Issue 1, 2013, Pages 84-96

  Stegemann Koniszewski, Sabine ^a,b   Gereke, Marcus ^a,c   Orrskog, Sofia ^e   Lienenklaus, Stefan ^a   Pasche, Bastian ^a   Bader, Sophie R ^d   Gruber, Achim D ^d   Akira, Shizuo ^f   Weiss, Siegfried ^a   Henriques Normark, Birgitta ^e   Bruder, Dunja ^a,c   Gunzer, Matthias ^b  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

^e KAROLINSKA INSTITUTE   (Sweden)

^f OSAKA UNIVERSITY   (Japan)

Author keywords

Bacterial superinfection; Influenza A virus; Innate immunity; Streptococcus pneumoniae; Toll like receptor 7

Indexed keywords

TOLL LIKE RECEPTOR 7;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL SUPERINFECTION; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL MODEL; FATALITY; FEMALE; HOST; INFLUENZA A; LUNG ALVEOLUS MACROPHAGE; MALE; MORTALITY; MOUSE; NONHUMAN; PHAGOCYTOSIS; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; SECONDARY PNEUMOCOCCAL DISEASE; VIRAL CLEARANCE; WILD TYPE;

EID: 84872267416     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000345112     Document Type: Article

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