Synthesis, anti-schistosomal activity and molecular modeling of two novel 8-hydroxyquinoline derivatives

Anti-Infective Agents

Volumn 11, Issue 1, 2012, Pages 31-40

  Eweas, Ahmad F ^a,b   Allam, Gamal ^a,c   Abu Elsaad, Abdelaziz S A ^a,c   Maghrabi, Ibrahim A ^a   ALGhamdi, Abdul Hamid ^c  

^a TAIF UNIVERSITY   (Saudi Arabia)

^b NATIONAL RESEARCH CENTRE   (Egypt)

^c Beni Suef University   (Egypt)

Author keywords

8 hydroxyquinoline; Anti schistosomal; Molecular docking; Thioredoxin glutatione reductase (TGR)

Indexed keywords

1 [(8 HYDROXYQUINOLIN 5 YL)SULFONYL] 3 METHYL 1H PYRAZOL 5(4H) ONE 4; 3 AMINO 1 [(8 HYDROXYQUINOLIN 5 YL)SULFONYL] 1H PYRAZOL 5(4H) ONE 3; 8 HYDROXYQUINOLINE 5 SULFONOHYDRAZIDE 2; 8 HYDROXYQUINOLINE 5 SULFONYL CHLORIDE 1; 8 QUINOLINOL DERIVATIVE; PRAZIQUANTEL; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIPROTOZOAL ACTIVITY; ARTICLE; BINDING AFFINITY; CELL DEATH; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; EGG LAYING; EGG PRODUCTION; FEMALE; MALE; MOLECULAR DOCKING; MOTOR ACTIVITY; MOUSE; NONHUMAN; SCHISTOSOMA MANSONI;

EID: 84872259429     PISSN: 22113525     EISSN: 22113533     Source Type: Journal    
DOI: 10.2174/22113626130104     Document Type: Article

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