Behavioral Stress Fails to Accelerate the Onset and Progression of Plaque Pathology in the Brain of a Mouse Model of Alzheimer's Disease

PLoS ONE

Volumn 8, Issue 1, 2013, Pages

  Yuan, Qiuju ^a   Su, Huanxing ^b   Chau, Wing Hin ^c   Toa Ng, Cheung ^c   Huang, Jian Dong ^c   Wu, Wutian ^c,d,e   Lin, Zhi Xiu ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF MACAU   (Macao)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIORAL STRESS; BRAIN CORTEX; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; HIPPOCAMPUS; HISTOPATHOLOGY; IMMOBILIZATION STRESS; MOUSE; NONHUMAN;

MUS; MUS MUSCULUS;

EID: 84872254790     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0053480     Document Type: Article

References (44)

1. Huang Y, Mucke L, (2012) Alzheimer mechanisms and therapeutic strategies. Cell 148: 1204-1222.
2. Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, et al. (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261: 921-923.
3. Hyman BT, Gomez-Isla T, Rebeck GW, Briggs M, Chung H, et al. (1996) Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease. Ann N Y Acad Sci 802: 1-5.
4. Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, et al. (1993) Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43: 1467-1472.
5. Selkoe DJ, (1999) Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 399: A23-A31.
6. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, et al. (1993) Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 90: 1977-1981.
7. Goedert M, Spillantini MG, (2006) A century of Alzheimer's disease. Science 314: 777-781.
8. Selkoe DJ, Schenk D, (2003) Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. Annu Rev Pharmacol Toxicol 43: 545-584.
9. Wilson RS, Schneider JA, Bienias JL, Arnold SE, Evans DA, et al. (2003) Depressive symptoms, clinical AD, and cortical plaques and tangles in older persons. Neurology 61: 1102-1107.
10. Wilson RS, Scherr PA, Hoganson G, Bienias JL, Evans DA, et al. (2005) Early life socioeconomic status and late life risk of Alzheimer's disease. Neuroepidemiology 25: 8-14.
11. Small DH, Mok SS, Bornstein JC, (2001) Alzheimer's disease and Abeta toxicity: from top to bottom. Nat Rev Neurosci 2: 595-598.
12. Spires TL, Hyman BT, (2005) Transgenic models of Alzheimer's disease: learning from animals. NeuroRx 2: 423-437.
13. Nithianantharajah J, Hannan AJ, (2006) Enriched environments, experience-dependent plasticity and disorders of the nervous system. Nat Rev Neurosci 7: 697-709.
14. Cotel MC, Jawhar S, Christensen DZ, Bayer TA, Wirths O, (2012) Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice. Neurobiol Aging 33: 96-107.
15. Cuadrado-Tejedor M, Ricobaraza A, Frechilla D, Franco R, Perez-Mediavilla A, et al. (2012) Chronic mild stress accelerates the onset and progression of the Alzheimer's disease phenotype in Tg2576 mice. J Alzheimers Dis 28: 567-578.
16. Devi L, Alldred MJ, Ginsberg SD, Ohno M, (2010) Sex- and brain region-specific acceleration of beta-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease. Mol Brain 3: 34.
17. Mayeux R, (2003) Epidemiology of neurodegeneration. Annu Rev Neurosci 26: 81-104.
18. Adlard PA, Perreau VM, Pop V, Cotman CW, (2005) Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J Neurosci 25: 4217-4221.
19. Ambree O, Leimer U, Herring A, Gortz N, Sachser N, et al. (2006) Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. Am J Pathol 169: 544-552.
20. Costa DA, Cracchiolo JR, Bachstetter AD, Hughes TF, Bales KR, et al. (2007) Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms. Neurobiol Aging 28: 831-844.
21. Lazarov O, Robinson J, Tang YP, Hairston IS, Korade-Mirnics Z, et al. (2005) Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 120: 701-713.
22. Arendash GW, Lewis J, Leighty RE, McGowan E, Cracchiolo JR, et al. (2004) Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: linkage of poorer cognitive performance to tau pathology in forebrain. Brain Res 1012: 29-41.
23. Wolf SA, Kronenberg G, Lehmann K, Blankenship A, Overall R, et al. (2006) Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biol Psychiatry 60: 1314-1323.
24. Jankowsky JL, Xu G, Fromholt D, Gonzales V, Borchelt DR, (2003) Environmental enrichment exacerbates amyloid plaque formation in a transgenic mouse model of Alzheimer disease. J Neuropathol Exp Neurol 62: 1220-1227.
25. Jankowsky JL, Melnikova T, Fadale DJ, Xu GM, Slunt HH, et al. (2005) Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease. J Neurosci 25: 5217-5224.
26. Bao AM, Meynen G, Swaab DF, (2008) The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Res Rev 57: 531-553.
27. Harvey SC, Shorto A, Viney ME, (2008) Quantitative genetic analysis of life-history traits of Caenorhabditis elegans in stressful environments. BMC Evol Biol 8: 15.
28. Swaab DF, Bao AM, Lucassen PJ, (2005) The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 4: 141-194.
29. Lemaire V, Koehl M, Le MM, Abrous DN, (2000) Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus. Proc Natl Acad Sci U S A 97: 11032-11037.
30. Buynitsky T, Mostofsky DI, (2009) Restraint stress in biobehavioral research: Recent developments. Neurosci Biobehav Rev 33: 1089-1098.
31. Lee KW, Kim JB, Seo JS, Kim TK, Im JY, et al. (2009) Behavioral stress accelerates plaque pathogenesis in the brain of Tg2576 mice via generation of metabolic oxidative stress. J Neurochem 108: 165-175.
32. Chishti MA, Yang DS, Janus C, Phinney AL, Horne P, et al. (2001) Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J Biol Chem 276: 21562-21570.
33. Jeong YH, Park CH, Yoo J, Shin KY, Ahn SM, et al. (2006) Chronic stress accelerates learning and memory impairments and increases amyloid deposition in APPV717I-CT100 transgenic mice, an Alzheimer's disease model. FASEB J 20: 729-731.
34. Chadda R, Devaud LL, (2005) Differential effects of mild repeated restraint stress on behaviors and GABA(A) receptors in male and female rats. Pharmacol Biochem Behav 81: 854-863.
35. Masuda J, Mitsushima D, Kimura F, (2004) Female rats living in small cages respond to restraint stress with both adrenocortical corticosterone release and acetylcholine release in the hippocampus. Neurosci Lett 358: 169-172.
36. Yuan Q, Xie Y, So KF, Wu W, (2003) Inflammatory response associated with axonal injury to spinal motoneurons in newborn rats. Dev Neurosci 25: 72-78.
37. Durairajan SS, Liu LF, Lu JH, Chen LL, Yuan Q, et al. (2012) Berberine ameliorates beta-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model. Neurobiol Aging.
38. Nomura M, Saito J, Ueta Y, Muglia LJ, Pfaff DW, et al. (2003) Enhanced up-regulation of corticotropin-releasing hormone gene expression in response to restraint stress in the hypothalamic paraventricular nucleus of oxytocin gene-deficient male mice. J Neuroendocrinol 15: 1054-1061.
39. Chagra SL, Zavala JK, Hall MV, Gosselink KL, (2011) Acute and repeated restraint differentially activate orexigenic pathways in the rat hypothalamus. Regul Pept 167: 70-78.
40. Zavala JK, Fernandez AA, Gosselink KL, (2011) Female responses to acute and repeated restraint stress differ from those in males. Physiol Behav 104: 215-221.
41. Sterrenburg L, Gaszner B, Boerrigter J, Santbergen L, Bramini M, et al. (2012) Sex-dependent and differential responses to acute restraint stress of corticotropin-releasing factor-producing neurons in the rat paraventricular nucleus, central amygdala, and bed nucleus of the stria terminalis. J Neurosci Res 90: 179-192.
42. Umriukhin PE, Koplik EV, Sudakov KV, (2012) Dizocilpine and cycloheximide prevent inhibition of c-Fos gene expression by delta sleep-inducing peptide in the paraventricular nucleus of the hypothalamus in rats with different resistance to emotional stress. Neurosci Lett 506: 184-187.
43. D'Alton S, George DR, (2011) Changing perspectives on Alzheimer's disease: thinking outside the amyloid box. J Alzheimers Dis 25: 571-581.
44. Jeong YH, Kim JM, Yoo J, Lee SH, Kim HS, et al. (2011) Environmental enrichment compensates for the effects of stress on disease progression in Tg2576 mice, an Alzheimer's disease model. J Neurochem 119: 1282-1293.