Design and synthesis of aza-flavones as a new class of xanthine oxidase inhibitors

Archiv der Pharmazie

Volumn 346, Issue 1, 2013, Pages 7-16

  Dhiman, Rajni ^a   Sharma, Sahil ^a   Singh, Gagandip ^b   Nepali, Kunal ^a   Singh Bedi, Preet Mohinder ^a  

^a GURU NANAK DEV UNIVERSITY   (India)

^b ISF COLLEGE OF PHARMACY   (India)

Author keywords

Bioisosterism; Flavones; Isosteric; Quinolones; Xanthine oxidase

Indexed keywords

2 (2 METHOXYPHENYL) QUINOLIN 4(1H) ONE; 2 (2,3 DIMETHOXYPHENYL)QUINOLIN 4(1H) ONE; 2 (2,5 DIMETHOXYPHENYL) QUINOLIN 4(1H) ONE; 2 (3,4 DIMETHOXYPHENYL) QUINOLIN 4(1H) ONE; 2 (3,4 METHYLENEDIOXYPHENYL) 1,4 DIHYDRO 4 OXOQUINOLINE; 2 (3,4,5 TRIMETHOXYPHENYL) QUINOLIN 4(1H) ONE; 2 (4 CHLOROPHENYL) QUINOLIN 4(1H) ONE; 2 (4 FLUOROPHENYL) QUINOLIN 4(1H) ONE; 2 (4 METHOXYPHENYL) QUINOLIN 4(1H) ONE; 2 (4 METHYLPHENYL) 4 QUINOLONE; 2 (NAPHTHALEN 1 YL) QUINOLIN 4(1H) ONE; 2 (PYRIDIN 4 YL) QUINOLIN 4(1H) ONE; 2 (THIOPHEN 2 YL)QUINOLIN 4(1H) ONE; 2 PHENYLQUINOLIN 4(1H) ONE; 2 STYRYLQUINOLIN 4(1H) ONE; AMINO ACID; FLAVONE DERIVATIVE; UNCLASSIFIED DRUG; XANTHINE OXIDASE INHIBITOR;

ARTICLE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; MOLECULAR MODEL; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACIDS; ANIMALS; AZA COMPOUNDS; CATTLE; DRUG DESIGN; FLAVONES; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; XANTHINE OXIDASE;

EID: 84872235042     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201200296     Document Type: Article

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