Physiological correlates of aggression and impulsivity in free-ranging female primates

Neuropsychopharmacology

Volumn 28, Issue 6, 2003, Pages 1045-1055

  Westergaard, Gregory C ^a   Suomi, Stephen J ^b   Chavanne, Tara J ^a   Houser, Lisa ^a   Hurley, Anne ^c   Cleveland, Allison ^a   Snoy, Philip J ^d   Higley, J Dee ^c  

^a LABS of Virginia Inc   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c National Institute of Alcohol Abuse and Alcoholism   (United States)

^d CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

5 HIAA; Aggression; Females; Impulsivity; Macaca mulatta; Serotonin

Indexed keywords

5 HYDROXYINDOLEACETIC ACID;

AGGRESSION; ANIMAL; ANIMAL BEHAVIOR; ARTICLE; BLOOD; CEREBROSPINAL FLUID; FEMALE; IMPULSIVENESS; MACACA; METABOLISM; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; SOCIAL BEHAVIOR;

AGGRESSION; ANIMALS; BEHAVIOR, ANIMAL; FEMALE; HYDROXYINDOLEACETIC ACID; IMPULSIVE BEHAVIOR; MACACA MULATTA; SOCIAL BEHAVIOR;

EID: 0041342083     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/sj.npp.1300171     Document Type: Article

References (60)

1. Abraham GE, Buster JE, Teller RC (1972). Radioimmunoassay of plasma cortisol. Anal Lett 5: 757-766.
2. Ballenger JC, Goodwin FK, Major LF, Brown GL (1979). Alcohol and central serotonin metabolism in man. Arch Gen Psychiatry 36: 224-227.
3. Banki CM, Molnar G, Fekete I (1981). Correlation of individual symptoms and other clinical variables with cerebrospinal fluid amine metabolites and tryptophan in depression. Arch Psychiatr Nervenkr 229: 345-353.
4. Bappenheim J, Tartabini A (1983). Different behavior patterns of mother-infant interactions. Acta Anthropogenet 7: 13-25.
5. Berman CM (1980). Early agonistic experience and rank acquisition among free-ranging infant rhesus monkeys. Int J Primatol 1: 153-170.
6. Berman CM (1983). Influence of close female relatives on peerpeer rank acquisition. In: Hinde RA (ed). Primate Social Relationships: An Integrated Approach. Sinauer Associates Inc.: Sunderland, MA. pp 157-159.
7. Bernstein IS, Ehardt CL (1986). Selective interference in rhesus monkey (Macaca mulatta) intragroup agonistic episodes by age-sex class. J Comp Psychol 100: 380-384.
8. Bernstein IS, Gordon TP (1974). The function of aggression in primate societies. Am Sci 62: 304-311.
9. Boelkins RC, Wilson AP (1972). Intergroup social dynamics of the Cayo Santiago rhesus with special reference to changes in group membership by males. Primates 13: 125-140.
10. Borg S, Kvande H, Liljeberg P, Mossberg D, Valverius P (1985). 5- Hydroxyindoleacetic acid in cerebrospinal fluid in alcoholic patients under different clinical conditions. Alcohol 2: 415-418.
11. Brown GL, Ebert MH, Goyer PF, Jimerson DC, Klein WJ, Bunney WEJ et al (1982). Aggression, suicide, and serotonin: relationships to CSF amine metabolites. Am J Psychiatry 139: 741-746.
12. Brown GL, Goodwin FK, Ballenger JC, Goyer PF, Major LF (1979). Aggression in humans correlates with cerebrospinal fluid amine metabolites. Psychiatry Res 1: 131-139.
13. de Waal F (1989). Peacemaking Among Primates, Vol. 5. Harvard University Press: Cambridge, MA.
14. Doudet D, Hommer D, Higley JD, Andreason PJ, Moneman R, Suomi SJ et al (1995). Cerebral glucose metabolism, CSF 5-HIAA levels, and aggressive behavior in rhesus monkeys. Am J Psychiatry 152: 1782-1787.
15. Fleming J, Mullen P, Sibthorpe B, Attelwell R, Bammer G (1998). The relationship between childhood sexual abuse and alcohol abuse in women—a case control study. Addiction 93: 1787-1798.
16. Harlow H (1965). Sexual behavior in rhesus monkeys. In: Beach F (ed). Sex and Behavior, Vol. 1. Wiley & Sons: New York. pp 234-265.
17. Hasegawa T, Hiraiwa M (1980). Social interactions of orphans observed in free-ranging troop of Japanese monkeys. Folia Primatol 33: 129-158.
18. Hausfater G (1972). Intergroup behavior of free-ranging rhesus monkeys (Macaca mulatta). Folia Primatol 18: 78-107.
19. Higley JD (in press). Aggression in Old World primates. In: Maestripieri D (ed). Primate Psychology: The Mind and Behavior of Human and Nonhuman Primates.
20. Higley JD, Hasert MF, Dodson A, Linnoila M, Suomi SJ (1992a). Treatment of excessive alcohol consumption using the serotonin reuptake inhibitor Sertraline in a nonhuman primate model of alcohol abuse. Paper Presented at Research Society on Alcoholism, San Diego, CA, June 13-18.
21. Higley JD, King ST, Hasert MF, Champoux M, Suomi SJ, Linnoila M (1996a). Stability of interindividual differences in serotonin function and its relationship to aggressive wounding and competent social behavior in rhesus macaque females. Neuropsychopharmacology 14: 67-76.
22. Higley JD, Linnoila M, Suomi SJ (1994). Ethological contributions: experiential and genetic contributions to the expression and inhibition of aggression in primates. In: Hersen M, Ammerman RT, Sisson L (eds). Handbook of Aggressive and Destructive Behavior in Psychiatric Patients. Plenum Press: New York. pp 17-32.
23. Higley JD, Mehlman PT, Higley SB, Fernald B, Vickers J, Lindell SG et al (1996b). Excessive mortality in young free-ranging male nonhuman primates with low cerebrospinal fluid 5-hydroxyin- doleacetic acid. Arch Gen Psychiatry 53: 537-543.
24. Higley JD, Mehlman PT, Poland RE, Taub DT, Suomi SJ, Linnoila M (1997). Aggression, social dominance, serotonin, and causal relationships. Biol Psychiatry 42: 306-307.
25. Higley JD, Mehlman PT, Poland RE, Taub DM, Vickers J, Suomi SJ et al (1996c). CSF testosterone and 5-HIAA correlate with different types of aggressive behaviors. Biol Psychiatry 40: 1067-1082.
26. Higley JD, Mehlman P, Taub D, Higley SB, Vickers JH, Suomi SJ et al (1992b). Cerebrospinal fluid monoamine and adrenal correlates of aggression in free-ranging rhesus monkeys. Arch Gen Psychiatry 49: 436-441.
27. Higley JD, Suomi SJ (1989). Temperamental reactivity in nonhuman primates. In: Kohnstamm GA, Bates JE, Rothbart MK (eds). Temperament in Childhood. John Wiley & Sons: New York. pp 153-167.
28. Higley JD, Suomi SJ (1996). Effect of reactivity and social competence on individual responses to severe stress in children: investigations using nonhuman primates. In: Pfeffer CR (ed). Intense Stress and Mental Disturbance in Children. American Psychiatric Press, Inc.: Washington, DC. pp 1-69.
29. Higley JD, Suomi SJ, Linnoila M (1996d). A nonhuman primate model of type II alcoholism? Part 2. Diminished social competence and excessive aggression correlates with low cerebrospinal fluid 5-hydroxyindoleacetic acid concentrations. Alcoholism: Clin Exp Res 20: 643-650.
30. Hiroeh U, Appleby L, Mortensen PB, Dunn G (2001). Death by homicide, suicide, and other unnatural causes in people with mental illness: a population-based study. Lancet 358: 2110-2112.
31. Jonsson EG, Norton N, Gustavsson JP, Oreland L, Owen MJ, Sedvall GC (2000). A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers. J Psychiatr Res 34: 239-244.
32. Kalin NH (1999). Primate models to understand human aggression. J Clin Psychiatry 60(Suppl 15): 29-32.
33. Kelley S (1998). Stress and coping behaviors of substance-abusing mothers. J Soc Pediatr Nurses 3: 103-112.
34. Koford CB (1965). Population dynamics of rhesus monkeys on Cayo Santiago. In: DeVore I (ed). Primate Behavior: Field Studies of Monkeys and Apes. Holt, Rinehart & Winston: New York. pp 53-110.
35. Kruesi MJ, Swedo S, Leonard H, Rubinow DR, Rapoport JL (1990). CSF somatostatin in childhood psychiatric disorders: a preliminary investigation. Psychiatry Res 33: 277-284.
36. Kyes RC, Botchin MB, Kaplan JR, Manuck SB, Mann JJ (1995). Aggression and brain serotonergic responsivity: response to slides in male macaques. Physiol Behav 57: 205-208.
37. Lindburg DG (1971). The rhesus monkey in North India: an ecological and behavioral study. In: Rosenblum LA (ed). Primate Behavior: Developments in Field and Laboratory Research, Vol. 2. Academic Press: New York. pp 1-106.
38. Linnoila VM, Virkkunen M (1992). Aggression, suicidality, and serotonin. J Clin Psychiatry 53: 46-51.
39. Linnoila M, Virkkunen M, Scheinin M, Nuutila A, Rimon R, Goodwin FK (1983). Low cerebrospinal fluid 5-hydroxyindolea- cetic acid concentration differentiates impulsive from nonimpulsive violent behavior. Life Sci 33: 2609-2614.
40. Manuck SB, Flory JD, McCaffery J, Matthews K, Mann J, Muldoon M (1998). Aggression, impulsivity, and central nervous system serotonergic responsivity in a nonpatient sample. Neuropsychopharmacology 19: 287-299.
41. Mason W (1960). The effects of social restriction on the behavior of rhesus monkeys: I. Free social behavior. J Comp Physiol Psychol 53: 582-589.
42. Mehlman PT, Higley JD, Faucher I, Lilly AA, Taub DM, Suomi S et al (1994). Low CSF 5-HIAA concentrations and severe aggression and impaired impulse control in nonhuman primates. Am J Psychiatry 151: 1485-1491.
43. Mehlman P, Higley JD, Faucher I, Lilly AA, Taub DM, Vickers JH et al (1995). Correlation of CSF 5-HIAA concentration with sociality and the timing of emigration in free-ranging primates. Am J Psychiatry 152: 907-913.
44. Mehlman PT, Higley JD, Fernald BJ, Sallee FR, Suomi SJ, Linnoila M (1997). CSF 5-HIAA, testosterone, and sociosexual behaviors in free-ranging male rhesus macaques in the mating season. Psychiatry Res 72: 89-102.
45. Mehlman PT, Westergaard GC, Hoos BJ, Sallee FR, Marsh S, Suomi SJ et al (2000). CSF 5-HIAA and nighttime activity in free- ranging primates. Neuropsychopharmacology 22: 210-218.
46. Mitchell G (1968). Attachment differences in male and female infant monkeys. Child Dev 39: 611-620.
47. Moss HB (1987). Serotonergic activity and disinhibitory psychopathy in alcoholism. Med Hypotheses 23: 353-361.
48. Preuss U, Schuckit M, Smith T, Danko G (2002). A comparison of alcohol-induced and independent depression in alcoholics with histories of suicide attempts. J Stud Alcohol 63: 498-502.
49. Redmond DEJ, Katz MM, Maas JW, Swann A, Casper R, Davis JM (1986). Cerebrospinal fluid amine metabolites. Relationships with behavioral measurements in depressed, manic, and healthy control subjects. Arch Gen Psychiatry 43: 938-947.
50. Roy A, De JJ, Linnoila M (1989). Cerebrospinal fluid monoamine metabolites and suicidal behavior in depressed patients. A 5-year follow-up study. Arch Gen Psychiatry 46: 609-612.
51. Scheinin M, Chang WH, Kirk KL, Linnoila M (1983). Simultaneous determination of 3-methoxy-4-hydroxyphenylglycol, 5-hydro- xyindoleacetic acid, and homovanillic acid in cerebrospinal fluid with high-performance liquid chromatography using electrochemical detection. Anal Biochem 131: 246-253.
52. Shively CA, Fontenot MB, Kaplan JR (1995). Social status, behavior, and central serotonergic responsivity in female cynomolgus monkeys. Am J Primatol 37: 333-340.
53. Soubrié P (1986). Reconciling the role of central serotonin neurons in human and animal behavior. Behav Brain Sci 9: 319-364.
54. Spencer-Booth Y (1968). The behavior of group companions towards rhesus monkey infants. Anim Behav 16: 541-557.
55. Taub DM, Mehlman PT (1989). Development of the Morgan Island Rhesus Monkey colony. Puerto Rico Health Sci J 8: 159-169.
56. Virkkunen M, De Jong J, Bartko J, Linnoila M (1989). Psychobiological concomitants of history of suicide attempts among violent offenders and impulsive fire setters. Arch Gen Psychiatry 46: 604-606.
57. Virkkunen M, Kallio E, Rawlings R, Tokola R, Poland RE, Guidotti A et al (1994a). Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51: 28-33.
58. Virkkunen M, Rawlings R, Tokola R, Poland RE, Guidotti A, Nemeroff C et al (1994b). CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51: 20-27.
59. Westergaard GC, Mehlman PT, Shoaf SE, Suomi SJ, Higley JD (1999). CSF 5-HIAA and aggression in female primates: species and interindividual differences. Psychopharmacology 146: 440-446.
60. Zuckerman M (1985). Sensation seeking, mania, and monoamines. Neuropsychobiology 13: 121-128.