-
1
-
-
80053246700
-
The role of targeted therapy in ovarian cancer
-
Banerjee S, Kaye S, (2011) The role of targeted therapy in ovarian cancer. Eur J Cancer 47Suppl 3: S116-130.
-
(2011)
Eur J Cancer
, vol.47
-
-
Banerjee, S.1
Kaye, S.2
-
3
-
-
84861860715
-
The changing view of high-grade serous ovarian cancer
-
Berns EM, Bowtell DD, (2012) The changing view of high-grade serous ovarian cancer. Cancer Res 72: 2701-2704.
-
(2012)
Cancer Res
, vol.72
, pp. 2701-2704
-
-
Berns, E.M.1
Bowtell, D.D.2
-
4
-
-
77958484951
-
The genesis and evolution of high-grade serous ovarian cancer
-
Bowtell DD, (2010) The genesis and evolution of high-grade serous ovarian cancer. Nat Rev Cancer 10: 803-808.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 803-808
-
-
Bowtell, D.D.1
-
5
-
-
84858236146
-
Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways
-
Hiss D, (2012) Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways. J Oncol 2012: 737981.
-
(2012)
J Oncol
, vol.2012
, pp. 737981
-
-
Hiss, D.1
-
6
-
-
84858853451
-
Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the ovarian cancer association consortium (OCAC)
-
Bolton KL, Ganda C, Berchuck A, Pharaoh PD, Gayther SA (2012) Role of common genetic variants in ovarian cancer susceptibility and outcome: progress to date from the ovarian cancer association consortium (OCAC). J Intern Med.
-
(2012)
J Intern Med.
-
-
Bolton, K.L.1
Ganda, C.2
Berchuck, A.3
Pharaoh, P.D.4
Gayther, S.A.5
-
7
-
-
77951784627
-
Ovarian cancer pathogenesis: a model in evolution
-
Karst AM, Drapkin R, (2010) Ovarian cancer pathogenesis: a model in evolution. J Oncol 2010: 932371.
-
(2010)
J Oncol
, vol.2010
, pp. 932371
-
-
Karst, A.M.1
Drapkin, R.2
-
8
-
-
56749103412
-
The cell of origin of ovarian epithelial tumours
-
Dubeau L, (2008) The cell of origin of ovarian epithelial tumours. Lancet Oncol 9: 1191-1197.
-
(2008)
Lancet Oncol
, vol.9
, pp. 1191-1197
-
-
Dubeau, L.1
-
9
-
-
79958807496
-
Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment
-
Barbolina MV, Burkhalter RJ, Stack MS, (2011) Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment. Biochem J 437: 1-12.
-
(2011)
Biochem J
, vol.437
, pp. 1-12
-
-
Barbolina, M.V.1
Burkhalter, R.J.2
Stack, M.S.3
-
10
-
-
83055196860
-
Wnt and hedgehog gene pathway expression in serous ovarian cancer
-
Schmid S, Bieber M, Zhang F, Zhang M, He B, et al. (2011) Wnt and hedgehog gene pathway expression in serous ovarian cancer. Int J Gynecol Cancer 21: 975-980.
-
(2011)
Int J Gynecol Cancer
, vol.21
, pp. 975-980
-
-
Schmid, S.1
Bieber, M.2
Zhang, F.3
Zhang, M.4
He, B.5
-
11
-
-
84858605181
-
WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/beta-catenin pathway
-
Yoshioka S, King ML, Ran S, Okuda H, MacLean JA, 2nd, et al (2012) WNT7A regulates tumor growth and progression in ovarian cancer through the WNT/beta-catenin pathway. Mol Cancer Res 10: 469-482.
-
(2012)
Mol Cancer Res
, vol.10
, pp. 469-482
-
-
Yoshioka, S.1
King, M.L.2
Ran, S.3
Okuda, H.4
MacLean 2nd, J.A.5
-
12
-
-
67449150167
-
A Wnt survival guide: from flies to human disease
-
Chien AJ, Conrad WH, Moon RT, (2009) A Wnt survival guide: from flies to human disease. J Invest Dermatol 129: 1614-1627.
-
(2009)
J Invest Dermatol
, vol.129
, pp. 1614-1627
-
-
Chien, A.J.1
Conrad, W.H.2
Moon, R.T.3
-
13
-
-
77954112841
-
Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers
-
Ying Y, Tao Q, (2009) Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers. Epigenetics 4: 307-312.
-
(2009)
Epigenetics
, vol.4
, pp. 307-312
-
-
Ying, Y.1
Tao, Q.2
-
14
-
-
34548455905
-
Roles of secreted frizzled-related proteins in cancer
-
Shi Y, He B, You L, Jablons DM, (2007) Roles of secreted frizzled-related proteins in cancer. Acta Pharmacol Sin 28: 1499-1504.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 1499-1504
-
-
Shi, Y.1
He, B.2
You, L.3
Jablons, D.M.4
-
15
-
-
12144291274
-
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer
-
Suzuki H, Watkins DN, Jair KW, Schuebel KE, Markowitz SD, et al. (2004) Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 36: 417-422.
-
(2004)
Nat Genet
, vol.36
, pp. 417-422
-
-
Suzuki, H.1
Watkins, D.N.2
Jair, K.W.3
Schuebel, K.E.4
Markowitz, S.D.5
-
16
-
-
67349239320
-
Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma
-
Jost E, Gezer D, Wilop S, Suzuki H, Herman JG, et al. (2009) Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma. Cancer Lett 281: 24-31.
-
(2009)
Cancer Lett
, vol.281
, pp. 24-31
-
-
Jost, E.1
Gezer, D.2
Wilop, S.3
Suzuki, H.4
Herman, J.G.5
-
17
-
-
34547770885
-
Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma
-
Huang J, Zhang YL, Teng XM, Lin Y, Zheng DL, et al. (2007) Down-regulation of SFRP1 as a putative tumor suppressor gene can contribute to human hepatocellular carcinoma. BMC Cancer 7: 126.
-
(2007)
BMC Cancer
, vol.7
, pp. 126
-
-
Huang, J.1
Zhang, Y.L.2
Teng, X.M.3
Lin, Y.4
Zheng, D.L.5
-
18
-
-
84857402982
-
Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients
-
Jacob F, Ukegijni K, Nixdorf S, Ford C, Olivier J, et al. (2012) Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patients. PLoS One 7: e31885.
-
(2012)
PLoS One
, vol.7
-
-
Jacob, F.1
Ukegijni, K.2
Nixdorf, S.3
Ford, C.4
Olivier, J.5
-
19
-
-
80052712201
-
The ins and outs of the epithelial to mesenchymal transition in health and disease
-
Nieto MA, (2011) The ins and outs of the epithelial to mesenchymal transition in health and disease. Annu Rev Cell Dev Biol 27: 347-376.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 347-376
-
-
Nieto, M.A.1
-
20
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
-
(2009)
Cell
, vol.139
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
21
-
-
77954860342
-
Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression
-
Micalizzi DS, Farabaugh SM, Ford HL, (2010) Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression. J Mammary Gland Biol Neoplasia 15: 117-134.
-
(2010)
J Mammary Gland Biol Neoplasia
, vol.15
, pp. 117-134
-
-
Micalizzi, D.S.1
Farabaugh, S.M.2
Ford, H.L.3
-
22
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
RESEARCH0034
-
Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034.
-
(2002)
Genome Biol
, vol.3
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
Poppe, B.4
Van Roy, N.5
-
23
-
-
0242361176
-
Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta
-
Rask K, Nilsson A, Brannstrom M, Carlsson P, Hellberg P, et al. (2003) Wnt-signalling pathway in ovarian epithelial tumours: increased expression of beta-catenin and GSK3beta. Br J Cancer 89: 1298-1304.
-
(2003)
Br J Cancer
, vol.89
, pp. 1298-1304
-
-
Rask, K.1
Nilsson, A.2
Brannstrom, M.3
Carlsson, P.4
Hellberg, P.5
-
24
-
-
18244389736
-
Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors
-
Yan D, Wiesmann M, Rohan M, Chan V, Jefferson AB, et al. (2001) Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta-catenin signaling is activated in human colon tumors. Proc Natl Acad Sci U S A 98: 14973-14978.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 14973-14978
-
-
Yan, D.1
Wiesmann, M.2
Rohan, M.3
Chan, V.4
Jefferson, A.B.5
-
25
-
-
0036149985
-
Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors
-
Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, et al. (2002) Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors. Mol Cell Biol 22: 1184-1193.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 1184-1193
-
-
Lustig, B.1
Jerchow, B.2
Sachs, M.3
Weiler, S.4
Pietsch, T.5
-
26
-
-
77950368590
-
Conductin/axin2 and Wnt signalling regulates centrosome cohesion
-
Hadjihannas MV, Bruckner M, Behrens J, (2010) Conductin/axin2 and Wnt signalling regulates centrosome cohesion. EMBO Rep 11: 317-324.
-
(2010)
EMBO Rep
, vol.11
, pp. 317-324
-
-
Hadjihannas, M.V.1
Bruckner, M.2
Behrens, J.3
-
27
-
-
84863895600
-
Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
-
Wu ZQ, Brabletz T, Fearon E, Willis AL, Hu CY, et al. (2012) Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc Natl Acad Sci U S A.
-
(2012)
Proc Natl Acad Sci U S A.
-
-
Wu, Z.Q.1
Brabletz, T.2
Fearon, E.3
Willis, A.L.4
Hu, C.Y.5
-
28
-
-
1242274540
-
Alteration of cell cycle regulators correlates with survival in epithelial ovarian cancer patients
-
Hashiguchi Y, Tsuda H, Inoue T, Nishimura S, Suzuki T, et al. (2004) Alteration of cell cycle regulators correlates with survival in epithelial ovarian cancer patients. Hum Pathol 35: 165-175.
-
(2004)
Hum Pathol
, vol.35
, pp. 165-175
-
-
Hashiguchi, Y.1
Tsuda, H.2
Inoue, T.3
Nishimura, S.4
Suzuki, T.5
-
29
-
-
84858439409
-
BRCA1-mediated signaling pathways in ovarian carcinogenesis
-
Karve TM, Li X, Saha T, (2012) BRCA1-mediated signaling pathways in ovarian carcinogenesis. Funct Integr Genomics 12: 63-79.
-
(2012)
Funct Integr Genomics
, vol.12
, pp. 63-79
-
-
Karve, T.M.1
Li, X.2
Saha, T.3
-
30
-
-
79954618976
-
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
-
Helland A, Anglesio MS, George J, Cowin PA, Johnstone CN, et al. (2011) Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers. PLoS One 6: e18064.
-
(2011)
PLoS One
, vol.6
-
-
Helland, A.1
Anglesio, M.S.2
George, J.3
Cowin, P.A.4
Johnstone, C.N.5
-
31
-
-
79956084010
-
Prognostic impact of p53, p27, and C-MYC on clinicopathological features and outcome in early-stage (FIGO I-II) epithelial ovarian cancer
-
Skirnisdottir IA, Sorbe B, Lindborg K, Seidal T, (2011) Prognostic impact of p53, p27, and C-MYC on clinicopathological features and outcome in early-stage (FIGO I-II) epithelial ovarian cancer. Int J Gynecol Cancer 21: 236-244.
-
(2011)
Int J Gynecol Cancer
, vol.21
, pp. 236-244
-
-
Skirnisdottir, I.A.1
Sorbe, B.2
Lindborg, K.3
Seidal, T.4
-
32
-
-
77956938052
-
Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling
-
von Marschall Z, Fisher LW, (2010) Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling. Biochem Biophys Res Commun 400: 299-304.
-
(2010)
Biochem Biophys Res Commun
, vol.400
, pp. 299-304
-
-
von Marschall, Z.1
Fisher, L.W.2
-
33
-
-
80054706701
-
Secreted Wnt "inhibitors" are not just inhibitors: regulation of extracellular Wnt by secreted Frizzled-related proteins
-
Mii Y, Taira M, (2011) Secreted Wnt "inhibitors" are not just inhibitors: regulation of extracellular Wnt by secreted Frizzled-related proteins. Dev Growth Differ 53: 911-923.
-
(2011)
Dev Growth Differ
, vol.53
, pp. 911-923
-
-
Mii, Y.1
Taira, M.2
-
34
-
-
0038783316
-
Secreted antagonists of the Wnt signalling pathway
-
Kawano Y, Kypta R, (2003) Secreted antagonists of the Wnt signalling pathway. J Cell Sci 116: 2627-2634.
-
(2003)
J Cell Sci
, vol.116
, pp. 2627-2634
-
-
Kawano, Y.1
Kypta, R.2
-
35
-
-
34250861254
-
Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer
-
Horvath LG, Lelliott JE, Kench JG, Lee CS, Williams ED, et al. (2007) Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer. Prostate 67: 1081-1090.
-
(2007)
Prostate
, vol.67
, pp. 1081-1090
-
-
Horvath, L.G.1
Lelliott, J.E.2
Kench, J.G.3
Lee, C.S.4
Williams, E.D.5
-
36
-
-
50349095325
-
Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells
-
Carmon KS, Loose DS, (2008) Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells. Mol Cancer Res 6: 1017-1028.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 1017-1028
-
-
Carmon, K.S.1
Loose, D.S.2
-
37
-
-
79551600015
-
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
-
Takebe N, Harris PJ, Warren RQ, Ivy SP, (2011) Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol 8: 97-106.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 97-106
-
-
Takebe, N.1
Harris, P.J.2
Warren, R.Q.3
Ivy, S.P.4
-
38
-
-
84861986053
-
Wnt/beta-Catenin Signaling and Disease
-
Clevers H, Nusse R, (2012) Wnt/beta-Catenin Signaling and Disease. Cell 149: 1192-1205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
39
-
-
80054083873
-
Targeting the Wnt pathway in cancer: the emerging role of Dickkopf-3
-
Veeck J, Dahl E, (2012) Targeting the Wnt pathway in cancer: the emerging role of Dickkopf-3. Biochim Biophys Acta 1825: 18-28.
-
(2012)
Biochim Biophys Acta
, vol.1825
, pp. 18-28
-
-
Veeck, J.1
Dahl, E.2
-
40
-
-
84860800881
-
A new validated mathematical model of the Wnt signalling pathway predicts effective combinational therapy by sFRP and Dkk
-
Kogan Y, Halevi-Tobias KE, Hochman G, Baczmanska AK, Leyns L, et al. (2012) A new validated mathematical model of the Wnt signalling pathway predicts effective combinational therapy by sFRP and Dkk. Biochem J 444: 115-125.
-
(2012)
Biochem J
, vol.444
, pp. 115-125
-
-
Kogan, Y.1
Halevi-Tobias, K.E.2
Hochman, G.3
Baczmanska, A.K.4
Leyns, L.5
|