Pilot study of changes in salivary metabolic profiles induced by template therapy

In Vivo

Volumn 26, Issue 6, 2012, Pages 1015-1020

  Tanaka, Shoji ^a   Taga, Hitoshi ^b   Maehara, Kiyoshi ^a   Kaneshima, Azusa ^a   Machino, Mamoru ^a   Onuma, Hiromi ^c   Kaneko, Miku ^c   Sakagami, Hiroshi ^a   Sugimoto, Masahiro ^c,d   Soga, Tomoyoshi ^c   Tomita, Masaru ^c  

^a MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

^b JR Tokyo General Hospital   (Japan)

^c KEIO UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Metabolite profiling; Salivary glycine; Template therapy

Indexed keywords

4 HYDROXYPHENYLACETIC ACID; ALANINE; GLYCINE; N ACETYLNEURAMINATE; PROLINE; SERINE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CAPILLARY ELECTROPHORESIS; CONSERVATIVE TREATMENT; FEMALE; HEADACHE; HUMAN; METABOLOMICS; PILOT STUDY; SALIVA; SALIVA ANALYSIS; SALIVA LEVEL; TEMPLATE THERAPY; TIME OF FLIGHT MASS SPECTROMETRY;

EID: 84872200034     PISSN: 0258851X     EISSN: 17917549     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Maehara K, Tsuruhara T, Hase Y, Fukuda Y, Sawada Y, Yamamoto Y, Nakamura S, Takesada M, Nakajima A, Ito H, Matsui T, Takada F, Ueda T, Guzay C and Sato S: A template therapy approach for non-specific complaints. Basal Facts 8: 22-35, 1986.
2. Nobili A and Adversi R: Relationship between posture and occlusion; A clinical and experimental investigation. J Craniomandib Pract 14: 274-285, 1996.
3. Milani RS, de Periere DD and Micallef J-P: Relationship between dental occlusion and visual focusing. J Craniomandib Pract 16: 109-118, 1998.
4. Tokita K, Ito R, Kawamura H, Sato Y, Terada K, Yamada M and Henomatsu H: Studies on teeth extraction phenomena. Comparative studies on electrocardiographic and histologic findings in rats, mice, hamsters and guinea-pigs. J Am College Cardiol 24: 975-976, 1960.
5. Abe K, Yokota Y, Kawazoe T, Hioki S, Kishimoto T and Dawes C: The effects of an incisal bite plane on rat submandibular gland. J Dent Res 62: 721-724, 1983.
6. Hioki S, Niwa K, Kishimoto T, Kawazoe T, Yokota Y, Abe K and Dawes C: The effects of an incisal bite plane on rat sublingual glands. J Dent Res 62: 715-721, 1983.
7. Ueda T: Effects of occlusal destruction on posture in rats. J Gifu Dent Soc 18: 192-202, 1991 (in Japanese).
8. Sumioka T: Systemic effects of the peripheral disturbance of the trigeminal system. Influence of the occlusal destruction in dogs. J Kyoto Pref Univ Med 98: 1077-1085, 1991.
9. Azuma Y, Maehara K, Tokunaga T, Hashimoto M, Ieoka K and Sakagami H: Systemic effects of the occlusal destruction in guinea pigs. In Vivo 13: 519-524, 1999.
10. Taga H, Azuma Y, Maehara K and Nomura S: Effects of changes in occlusal vertical dimension on heart rate fluctuations in guinea pigs. In Vivo 28: 177-182, 2012
11. Soga T, Baran R, Suematsu M, Ueno Y, Ikeda S, Sakurakawa T, Kakazu Y, Ishikawa T, Robert M, Nishioka T and Tomita M: Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption. J Biol Chem 281: 16768-16776, 2006.
12. Sugimoto M, Wong DT, Hirayama A, Soga T and Tomita M: Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics 6: 78-95, 2010.
13. Soga T, Igarashi K, Ito C, Mizobuchi K, Zimmermann HP and Tomita M: Metabolomic profiling of anionic metabolites by capillary electrophoresis mass spectrometry. Analytical chemistry 81: 6165-6174, 2009.
14. Sugimoto M, Kawakami M, Robert M, Soga T and Tomita M: Bioinformatics tools for mass spectroscopy-based metabolomic data processing and analysis. Curr Bioinform 7: 96-108, 2012.
15. Van Wuyckhuyse BC, Perinpanayagam HER, Bevacqua D, Raubertas RFm Billings RJ, Bowen WH and Tabak LA: Association of free arginine and lysine concentrations in human parotid saliva with caries experience. J Dent Res 74: 686-690, 1995.
16. Fonteles CSR, Guerra MH, Ribeiro TR, Mendonça DN, de Carualho CBM, Monteiro AJ, Toyama DO, Toyama MH and Fonteles MC: Association of free amino acids with caries experience and mutansstreptococci levels in whole saliva of children with early childhood caries. Arch Oral Biol 54: 80-85, 2009.
17. Syrjänen S, Piironen P and Markkanen H: Free amino acid composition of wax-stimulated whole saliva in human subjects with healthy periodontium, severe chronic periodontitis and post-juvenile periodontitis. Arch Oral Biol 29: 735-738, 1984.
18. Syrjänen S, Piironen P and Markkanen H: Free amino acid content of wax-stimulated human whole saliva as related to periodontal disease. Arch Oral Biol 32: 607-610, 1987.
19. Syrjänen SM, Alakuijala P, Markkanen SO and Markkanen H: Free amino acid levels in oral fluids of normal subjects and patients with periodontal disease. Arch Oral Biol 35: 189-193, 1990.
20. Liappis N, Pohl B, Weber HP and el-Karkani H: Free amino acids in saliva of children with phenylketonuria. Klin Padiatr 198: 25-28,1986.
21. Rajda C, Tajti J, Komoróczy R, Seres E, Klivényi P and Vécsei L: Amino acids in the saliva of patients with migraine. Headache 39: 644-649, 1999.
22. Linkosalo E, Markkanen H and Syrjanen S: Effects of a lactoovo vegetarian diet on the free amino acid composition of wax-stimulated whole human saliva. J Nutr 115: 588-592, 1985.
23. Takeda I, Stretch C, Barnaby P, Bhatnager K, Rankin K, Fu H, Weljie A, Jha N and Slupsky C: Understanding the human salivary metabolome. NMR Biomed 22: 577-584, 2009.
24. Bertram HC, Eggers N and Eller N: Potential of human saliva for nuclear magnetic resonance-based metabolomics and for health-related biomarker identification. Anal Chem 81: 9188-9193, 2009.
25. Tanaka S, Machino M, Akita S, Yokote Y and Sakagami H: Changes in salivary amino acid composition during aging. In Vivo 24: 853-856, 2010.
26. Maehara K, Taga H, Takayama F and Sakagami H: Biochemical Analysis of Occlusal Destruction. 48th Japanese Association for Oral Biology, Tsurumi, Kanagawa, Japan, 2006 abstract poster no. 374.
27. Carmans S, Hendriks JJ, Thewissen K, Van den Eynden J, Stinissen P, Rigo JM and Hellings N: The inhibitory neurotransmitter glycine modulates macrophage activity by activation of neutral amino acid transporters. J Neurosci Res 88: 2420-2430, 2010.
28. Rausch-Fan X, Ulm C, Jensen-Jarolim E, Shcedle A, Boltz-Nitulescu G, Rausch WD and Matejka M: Interleukin-1β-inducedprostaglandin E2 production by human gingival fibroblasts is upregulated by glycine. J Periodontol 76: 1182-1188, 2005.
29. Tanaka J, Toku K, Matsuda S, Sudo S, Fujita H, Sakanaka M and Maeda N: Induction of resting microglia in culture medium devoid of glycine and serine. Glia 24: 198-215, 1998.
30. McCarty MF, Barroso-Aranda J and Contreras F: The hyperpolarizing impact of glycine on endothelial cells may be anti-atherogenic. Med Hypotheses 73: 263-264, 2009.
31. Okoto T and Awhin EP: Glycine reduces cadmium-induced alterations in the viability and activation of macrophage U937 cells. Food Chem Toxicol 48: 536-538, 2010.
32. Thurman RG, Zhong Z, von Frankenberg M, Stachlewitz RF and Bunzendahl H: Prevention of cyclosporine-induced nephrotoxicity with dietary glycine. Transplantation 63: 1661-1667, 1997.
33. Benko T, Freda S, Gu Y, Best J, Baba HA, Schlaak JF, de Groot H, Fandrey J and Rauen U: Glycine pretreatment ameliorates liver injury after partial hepatectomy in the rat. J Invest Surg 23:12-20, 2010.
34. You HB, Wang Q, Li XH, Chen XF, Liu Zj and Gong JP: The protection mechanisms of glycine against liver injury induced by lipopolysaccharides. Zhonghua Gan Zang Bing Za Zhi 14: 574-577, 2006 (in Chinese).
35. Zinellu A, Sotgia S, Pisanu E, Scanu B, Sanna M, Usai MF, Chessa R, Deiana L and Carru C: Quantification of neurotransmitter amino acids by capillary electrophoresis laser-induced fluorescence detection in biological fluids. Anal Bioanal Chem 398: 1973-1978, 2010.
36. Hegde AM, Kavita R, Sushma KS and Suchetha S: Salivary sialic acid levels and dental health in children with congenital heart disease. J Clin Pediatr Dent 36: 293-296, 2012.
37. Oktay S, Basar I, Emekli-Alturfan E, Malali E, Elemek E, Ayan F, Koldas L, Noyan U and Emekli N: Serum and saliva sialic acid in periodontitis patients with and without cardiovascular disease. Pathophysiol Haemost Thromb 37: 67-71, 2010.
38. Ozturk LK, Emekli-Alturfan E, Kasikci E, Demir G and Yarat A: Salivary total sialic acid levels increase in breast cancer patients: A preliminary study. Med Chem 7: 443-447, 2011.
39. O'Connor KE, Witholt B and Duetz W: p-Hydroxyphenylacetic acid metabolism in Pseudomonas putida F6. J Bacteriol 183:928-933, 2001.