Glycine reduces cadmium-induced alterations in the viability and activation of macrophage U937 cells

Food and Chemical Toxicology

Volumn 48, Issue 2, 2010, Pages 536-538

  Okoko, Tebekeme ^a   Awhin, Ejiro Prosper ^b  

^a NIGER DELTA UNIVERSITY   (Nigeria)

^b DELTA STATE UNIVERSITY   (Nigeria)

Author keywords

Antioxidant; Cadmium; Glycine; Macrophage; Nitric oxide

Indexed keywords

CADMIUM; CADMIUM CHLORIDE; CATALASE; GLYCINE; INTERLEUKIN 1; INTERLEUKIN 6; NITRIC OXIDE; PHORBOL 13 ACETATE 12 MYRISTATE; TUMOR NECROSIS FACTOR ALPHA;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL ACTIVATION; CELL CULTURE; CELL STRAIN U937; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MACROPHAGE; PHASE TRANSITION; SUPERNATANT;

ANTIOXIDANTS; BIOLOGICAL MARKERS; CADMIUM CHLORIDE; CATALASE; CELL SURVIVAL; CULTURE MEDIA, CONDITIONED; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; GLYCINE; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; NITRIC OXIDE; U937 CELLS;

EID: 75049084339     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.11.027     Document Type: Article

References (34)

1. Aebi H. Catalase in vitro. Methods in Enzymology 105 (1984) 121-126
2. Afshar, M., Ghazaei, S., Saad, E., 2000. Determination of cadmium in amol and Thailand rice. Fourth international Iranian Congress on poisoning, Tehran, Iran, p. 44.
3. Baker T.K., VanVooren H.B., Smith W.C., and Carfagna M.A. Involvement of calcium channels in the sexual dimorphism of cadmium-induced hepatotoxicity. Toxicology Letters 137 (2003) 185-192
4. Berglund M., Akesson A., Bjellerup P., and Vahter M. Metal-bone interactions. Toxicology Letters 112-113 (2002) 219-225
5. Borges L.P., Brandao R., Godoi B., Nogueira C.W., and Zeni G. Oral administration of diphenyl diselenide protects against cadmium-induced liver damage in rats. Chemico-Biological Interactions 171 (2008) 15-25
6. Chabrier P.E., Demerle-Pallardy C., and Auguet M. Nitric oxide synthases; targets for therapeutic strategies in neurological diseases. Cell and Molecular Life Sciences 55 (1999) 1029-1035
7. Dawson K.M., Collins J.L., and Baltz J.M. Osmolarity-dependent glycine accumulation indicates a role for glycine as an organic osmolyte in early preimplantation mouse embryos. Biology of Reproduction 59 (1998) 225-232
8. Domingo J.L. Metal-induced developmental toxicity in mammals: a review. Journal of Toxicology and Environmental Health 42 (1994) 123-141
9. Fotakis G., and Timbrell J.A. Role of trace elements in cadmium chloride uptake in hepatoma cell lines. Toxicology Letters 164 (2006) 97-103
10. Galan A., Troyano A., Vilaboa N.R., Fenandez C., de Blas E., and Aller P. Modulation of the stress response during apoptosis and necrosis induction in cadmium-treated U-937 human promonocytic cells. Biochimie and Biophysics 1538 (2001) 38-46
11. Goldsby A.G., Kindt T.J., Osborn B.O., and Kuby J. Hypersensitivity reactions. Immunology. fifth ed. (2003), Freeman and Company 381-382
12. Hsieh Y.H., Kuo P.M., Chien S.C., Shyur L.F., and Wang S.Y. Effects of Chamaecyparis formosensis Matasumura extractivities on lipopolysaccharide-induced release of nitric oxide. Phytomedicine 14 (2007) 675-680
13. Hovland D.N., Machado A.F., Scott W.J., and Collins M.D. Differential sensitivity of the SWV and C57BL/6 mouse strains to the teratogenic action of single administrations of cadmium given throughout the period of anterior neuropore closure. Teratology 60 (1999) 13-21
14. Hwang B.Y., Lee J.H., Koo T.H., Hong Y.S., Ro I.S., Lee K.S., and Lee J.J. Furanoligularenone, an eremophilane from Ligularia fischerri inhibits the lipopolysaccharide-induced production of nitric oxide and prostaglandin E2 in macrophage RAW264.7 cells. Planta Medica 68 (2002) 101-105
15. International Agency for Research on Cancer, 1993. IARC Monographs on the Evaluation of Carcinogenic Risk to Humans, vol. 58, pp. 119-237.
16. Joyce D.A., and Steer J.H. Differentiation of U-937 promonocytic cell line induced by phorbol myristate acetate or retinoic acid: effect of aurothiomalate. Agents Actions 37 (1992) 305-310
17. Keefer L.K., and Wink D. DNA damage and nitric oxide. Advances in Experimental Medicine and Biology 387 (1996) 177-185
18. Klassen C.D., Liu L., and Choudhuri S. Metallothionein: an intracellular protein to protect against cadmium toxicity. Annual Reviews in Pharmacology and Toxicology 39 (1999) 267-294
19. 2+) administered via osmotic minipumps to gravid CF-1 mice. Toxicology Letters 76 (1995) 195-202
20. Matilla B., Mauriz J.L., Culebras J.M., Gonzalez-Gallego J., and González P. Glycine: a cell-protecting anti-oxidant nutrient. Nutrición Hospitalaria 17 (2002) 2-9
21. Meng F., and Lowell C.A. Lipopolysaccharide-induced macrophage activation and signal transduction in the absence of Src family kinases Hck, Fgr, and Lyn. Journal of Experimental Medicine 189 (1997) 1661-1670
22. Okoko T., and Oruambo I.F. Garcinia kola extract reduced lipopolysaccharide activation of macrophages using U-937 cells as a model. African Journal Biotechnology 7 (2008) 792-795
23. Okoko T., and Oruambo I.F. Inhibitory activity of quercetin and its metabolite on lipopolysaccharide-induced activation of macrophage U-937 cells. Food and Chemical Toxicology 47 (2009) 809-812
24. Paniagua-Castro N., Escalona-Cardoso G., and Chamorro-Cevallos G. Glycine reduces cadmium-induced teratogenicity in mice. Reproductive Toxicology 23 (2007) 92-97
25. Paniagua-Castro N., Escalona-Cardoso G., Madrigal-Bujaidar E., Martinez-Galero E., and Chamorro-Cevallos G. Protection against cadmium-induced teratogenicity in vitro by glycine. Toxicology in Vitro 22 (2008) 75-79
26. Rikans L.E., and Yamano T. Mechanisms of cadmium-mediated acute hepatotoxicity. Journal of Biochemistry and Molecular Toxicology 14 (2000) 110-117
27. Roitt I., Brostoff J., and Male D. Hypersensitivity-type III. Immunology. sixth ed. (2002), Moshby 357
28. Surh Y.J., Chun K.S., Cha H.H., Han S.S., Keun Y.S., Park K.K., and Lee S.S. Molecular mechanisms underlying chemoprotective activities of anti-inflammatory phytochemicals; down regulation of cox-2, and iNOS through suppression of NF-kB activation. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 480-481 (2001) 243-268
29. Tamir S., and Tannenbaum S.R. The role of nitric oxide (NO) in the carcinogenesis process. Biochimie Biophysics Acta 1288 (1996) F31-F36
30. Thijssen S., Cuypers S.A., Maringwa J., Smeets K., Horemans N., Lambrichts I., and Kerkhove E.V. Low cadmium exposure triggers a biphasic oxidative stress response in mice kidneys. Toxicology 236 (2007) 29-41
31. Wang Y., Fang J., Leonard S.S., and Rao K.M. Cadmium inhibits the electron transfer chain and induces reactive oxygen species. Free Radical Biological Medicine 36 (2004) 1434-1443
32. Wheeler W., Stachlewitz R.F., Yamashina S., Ikejima K., Morrow A.L., and Thurman R.G. Glycine-gated chloride channels in neutrophils attenuate calcium influx and superoxide production. FASEB J. 14 (2000) 476-484
33. World Health Organisation. International Programme on Chemical Safety, Environment Health Criteria, No. 134 (2002), Cadmium, Geneva
34. Zhong A., Wheeler M.D., Li X., Froh M., Schener P., Yin M., Bunzendaul H., Bradford B., and Lemasters J.J. l-Glycine: a novel antiinflammatory, immunomodulatory, and cytoprotective agent. Current Opinion in Clinical Nutrition and Metabolic Care 6 (2003) 229-240