PKD2 and PKD3 promote prostate cancer cell invasion by modulating NF-κB- and HDAC1-mediated expression and activation of uPA

Journal of Cell Science

Volumn 125, Issue 20, 2012, Pages 4800-4811

  Zou, Zhipeng ^a   Zeng, Fangyin ^a   Xu, Wanfu ^a   Wang, Chunxia ^a   Ke, Zhiyong ^a   Wang, Q Jane ^b   Deng, Fan ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

HDAC1; Invasion; NF B; PKD; Prostate cancer; uPA

Indexed keywords

GELATINASE B; HISTONE DEACETYLASE 1; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 2; POLYCYSTIN; POLYCYSTIN 2; POLYCYSTIN 3; SERINE; TRANSCRIPTION FACTOR RELA; UNCLASSIFIED DRUG; UROKINASE;

ARTICLE; CANCER CELL; CELL INVASION; CELL MIGRATION; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROSTATE CANCER; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION TERMINATION;

CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONE DEACETYLASE 1; HUMANS; MALE; MATRIX METALLOPROTEINASE 9; NEOPLASM INVASIVENESS; PHOSPHORYLATION; PROSTATIC NEOPLASMS; PROTEIN KINASE C; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; TRANSCRIPTIONAL ACTIVATION; TRPP CATION CHANNELS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84872191888     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.106542     Document Type: Article

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