Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation

Journal of Cell Science

Volumn 125, Issue 19, 2012, Pages 4555-4566

  Isabelle, Maxim ^a   Gagné, Jean Philippe ^a   Gallouzi, Imed Eddine ^b   Poirier, Guy G ^a  

^a University Laval   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

G3BP; pADPr; Quantitative proteomics; SILAC; Stress granules

Indexed keywords

BINDING PROTEIN; G3BP PROTEIN; LEPTOMYCIN B; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN SH3; UNCLASSIFIED DRUG;

ARTICLE; BIOINFORMATICS; CELL GRANULE; CELL STRESS; CELLULAR DISTRIBUTION; DNA ALKYLATION; DNA DAMAGE; EXPRESSION VECTOR; GENOTOXICITY; HELA CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOFLUORESCENCE; MOLECULAR IMAGING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEOMICS; STRESS GRANULE;

ALKYLATION; AMINO ACID SEQUENCE; BLOTTING, WESTERN; CARRIER PROTEINS; CLUSTER ANALYSIS; CYTOPLASMIC GRANULES; DNA; DNA DAMAGE; FATTY ACIDS, UNSATURATED; GREEN FLUORESCENT PROTEINS; HELA CELLS; HUMANS; IMAGING, THREE-DIMENSIONAL; ISOTOPE LABELING; METHYLNITRONITROSOGUANIDINE; MOLECULAR SEQUENCE DATA; POLY ADENOSINE DIPHOSPHATE RIBOSE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTEOMICS; REPRODUCIBILITY OF RESULTS; STRESS, PHYSIOLOGICAL; SUBCELLULAR FRACTIONS; TIME FACTORS;

EID: 84872189805     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.106963     Document Type: Article

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