Mutant huntingtin affects endocytosis in striatal cells by altering the binding of AP-2 to membranes

Experimental Neurology

Volumn 241, Issue 1, 2013, Pages 75-83

  Borgonovo, Janina E ^a   Troncoso, Mariana ^a,c   Lucas, José J ^b   Sosa, Miguel A ^a,c  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

^b CSIC   (Spain)

^c UNIVERSIDAD NACIONAL DE CUYO   (Argentina)

Author keywords

Clathrin coated vesicles; Endocytosis; Huntingtin; HuntingtonD s disease; Neurodegeneration

Indexed keywords

COAT PROTEIN; HUNTINGTIN; MUTANT PROTEIN; POLYGLUTAMINE; PROTEIN AP 2; PROTEIN AP 2 ALPHA SUBUNIT; QUINOLINIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CONTROLLED STUDY; CORPUS STRIATUM; CYTOSOL; ENDOCYTOSIS; INTERNALIZATION; MEMBRANE BINDING; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEFECT; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; STRIATAL CELL;

ANIMALS; CELL ADHESION; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; CLATHRIN; CORPUS STRIATUM; CYTOSOL; ENDOCYTOSIS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MUTATION; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; PROTEIN BINDING; QUINOLINIC ACID; STATISTICS, NONPARAMETRIC; TIME FACTORS; TRANSCRIPTION FACTOR AP-2; TRANSFERRIN;

EID: 84872183040     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2012.11.025     Document Type: Article

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