Binding of AP-2 adaptor complex to brain membrane is regulated by phosphorylation of proteins

Biochemical and Biophysical Research Communications

Volumn 330, Issue 3, 2005, Pages 695-700

  Alberdi, A ^a   Sartor, T ^a   Sosa, M A ^a  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

ATP; Brain; Clathrin adaptors; Membranes; Protein phosphorylation; Vesicular traffic

Indexed keywords

ALKALINE PHOSPHATASE; CYCLOSPORIN; PROTEIN DERIVATIVE; SERINE; TRANSCRIPTION FACTOR AP 2; TYRPHOSTIN;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BRAIN MEMBRANE; CELL FRACTIONATION; COMPLEX FORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; INCUBATION TIME; MEMBRANE BINDING; MOLECULAR BIOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

EID: 16244388958     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.03.038     Document Type: Article

References (21)

1. S.D. Conner, and S.L. Schmid Differential requirements for AP-2 in clathrin-mediated endocytosis J. Cell Biol. 162 2003 773 779
2. J. Hirst, and M.S. Robinson Clathrin and adaptors Biochim. Biophys. Acta 1404 1998 173 193
3. T. Kirchhausen Adaptors for clathrin-mediated traffic Annu. Rev. Cell Dev. Biol. 15 1999 705 732
4. A. Wilde, and F.M. Brodsky In vivo phosphorylation of adaptors regulates their interaction with clathrin J. Cell Biol. 135 1996 635 645
5. A. Fingerhut, K. von Figura, and S. Honing Binding of AP2 to sorting signals is modulated by AP2 phosphorylation J. Biol. Chem. 276 2001 5476 5482
6. S.D. Conner, and S.L. Schmid Identification of an adaptor-associated kinase, AAK1, as a regulator of clathrin-mediated endocytosis J. Cell Biol. 156 2002 921 929
7. F. Huang, X. Jiang, and A. Sorkin Tyrosine phosphorylation of the β2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking J. Biol. Chem. 278 2003 43411 43417
8. M.A. Sosa, F. Bertini, K. von Figura, and A. Hille-Rehfeld Is an ATPase involved in uncoating of plasma membrane adaptor complex AP-2? FEBS Lett. 407 1997 173 176
9. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
10. M.A. Cousin, and P.J. Robinson The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis Trends Neurosci. 24 2001 659 665
11. E. Smythe, L.L. Carter, and S.L. Schmid Cytosol- and clathrin-dependent stimulation of endocytosis in vitro by purified adaptors J. Cell Biol. 119 1992 1163 1171
12. M.N. Seaman, C.L. Ball, and M.S. Robinson Targeting and mistargeting of plasma membrane adaptors in vitro J. Cell Biol. 123 1993 1093 1105
13. M.A. West, N.A. Bright, and M.S. Robinson The role of ADP-ribosylation factor and phospholipase D in adaptor recruitment J. Cell Biol. 138 1997 1239 1254
14. L.A. Hannan, S.L. Newmyer, and S.L. Schmid ATP- and cytosol-dependent release of adaptor proteins from clathrin-coated vesicles: a dual role for Hsc70 Mol. Biol. Cell 9 1998 2217 2229
15. A. Umeda, A. Meyerholz, and E. Ungewickell Identification of the universal cofactor (auxilin 2) in clathrin coat dissociation Eur. J. Cell Biol. 79 2000 336 342
16. J.R. Morgan, K. Prasad, S. Jin, G.J. Augustine, and E.M. Lafer Uncoating of clathrin-coated vesicles in presynaptic terminals: roles for Hsc70 and auxilin Neuron 32 2001 289 300
17. P. Ghosh, and S. Kornfeld AP-1 binding to sorting signals and release from clathrin-coated vesicles is regulated by phosphorylation J. Cell Biol. 160 2003 699 708
18. D. Ricotta, S.D. Conner, S.L. Schmid, K. von Figura, and S. Honing Phosphorylation of the AP2 μ subunit by AAK1 mediates high affinity binding to membrane protein sorting signals J. Cell Biol. 156 2002 791 795
19. A.P. Jackson, A. Flett, C. Smythe, L. Hufton, F.R. Wettey, and E. Smythe Clathrin promotes incorporation of cargo into coated pits by activation of the AP2 adaptor μ2 kinase J. Cell Biol. 163 2003 231 236
20. I. Gaidarov, and J.H. Keen Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits J. Cell Biol. 146 1999 755 764
21. G. Rohde, D. Wenzel, and V. Haucke A phosphatidylinositol (4,5)-bisphosphate binding site within μ2-adaptin regulates clathrin-mediated endocytosis J. Cell Biol. 158 2002 209 214