Human mesenchymal stem cells shift CD8+ T cells towards a suppressive phenotype by inducing tolerogenic monocytes

Journal of Cell Science

Volumn 125, Issue 19, 2012, Pages 4640-4650

  Hof Nahor, Irit ^a   Leshansky, Lucy ^a   Shivtiel, Shoham ^a   Eldor, Liron ^b   Aberdam, Daniel ^a   Itskovitz Eldor, Joseph ^a,b   Berrih Aknin, Sonia ^c  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b Rambam Health Care Campus ^*  (Israel)

^c Sorbonne Université   (France)

Author keywords

CD8+ cells; Human mesenchymal stem cells; Humanized mice; Immunoregulation; Monocytes

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD8 ANTIGEN; COMPLEMENT COMPONENT C5A RECEPTOR; GAMMA INTERFERON; GRANZYME B; HERMES ANTIGEN;

ADULT; ANIMAL EXPERIMENT; ANTIGEN EXPRESSION; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; MESENCHYMAL STEM CELL; MONOCYTE; MOUSE; NONHUMAN; PHENOTYPE; POLYCLONAL ACTIVATION; PRIORITY JOURNAL;

ADULT; ANIMALS; ANTIGENS, CD14; ANTIGENS, CD8; BIOLOGICAL MARKERS; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; DOWN-REGULATION; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNIZATION; LYMPHOCYTE ACTIVATION; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MONOCYTES; PHENOTYPE; TRANSCRIPTION, GENETIC;

MUS;

EID: 84872180528     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.108860     Document Type: Article

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