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Volumn 251, Issue 2, 2008, Pages 131-136

The immunosuppressive effects of human bone marrow-derived mesenchymal stem cells target T cell proliferation but not its effector function

Author keywords

Immunosuppression; Mesenchymal stem cells; T cells

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD69 ANTIGEN; INTERLEUKIN 2 RECEPTOR ALPHA; MITOGENIC AGENT; PHYTOHEMAGGLUTININ;

EID: 47249117877     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2008.04.009     Document Type: Article
Times cited : (169)

References (30)
  • 2
    • 27944435821 scopus 로고    scopus 로고
    • Clarification of the nomenclature for MSC: the international society for cellular therapy position statement
    • Horwitz E.E. Clarification of the nomenclature for MSC: the international society for cellular therapy position statement. Cytotherapy 7 (2005) 393-395
    • (2005) Cytotherapy , vol.7 , pp. 393-395
    • Horwitz, E.E.1
  • 6
    • 27144544587 scopus 로고    scopus 로고
    • Isolation and phenotypical characterization of mesenchymal stem cells from human fetal thymus
    • Rzhaninova A.A., Gornostaeva S.N., and Goldshtein D.V. Isolation and phenotypical characterization of mesenchymal stem cells from human fetal thymus. Bull. Exp. Biol. Med. 139 (2005) 134-140
    • (2005) Bull. Exp. Biol. Med. , vol.139 , pp. 134-140
    • Rzhaninova, A.A.1    Gornostaeva, S.N.2    Goldshtein, D.V.3
  • 7
    • 0034689058 scopus 로고    scopus 로고
    • An essential role for thymic mesenchyme in early T cell development
    • Suniara R.K., Jenkinson E.J., and Owen J.J. An essential role for thymic mesenchyme in early T cell development. J. Exp. Med. 191 (2000) 1051-1056
    • (2000) J. Exp. Med. , vol.191 , pp. 1051-1056
    • Suniara, R.K.1    Jenkinson, E.J.2    Owen, J.J.3
  • 8
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Nicola M., Carlo-Stella C., Magni M., Milanesi M., Longoni P.D., Matteucci P., Grisanti S., and Gianni A.M. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99 (2000) 3838-3843
    • (2000) Blood , vol.99 , pp. 3838-3843
    • Di Nicola, M.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 9
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation
    • Tse W.T., Pendleton J.D., Beyer W.M., Egalka M.C., and Guinan E.C. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation. Transplantation 75 (2003) 389-397
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3    Egalka, M.C.4    Guinan, E.C.5
  • 10
    • 0141886188 scopus 로고    scopus 로고
    • Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens
    • Potian J.A., Aviv H., Ponzio N.M., Harrison J.S., and Rameshwar P. Veto-like activity of mesenchymal stem cells: functional discrimination between cellular responses to alloantigens and recall antigens. J. Immunol. 171 (2003) 3426-3434
    • (2003) J. Immunol. , vol.171 , pp. 3426-3434
    • Potian, J.A.1    Aviv, H.2    Ponzio, N.M.3    Harrison, J.S.4    Rameshwar, P.5
  • 11
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M., Glennie S., Dyson J., Scott D., Laylor R., Simpson E., and Dazzi F. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 101 (2003) 3722-3729
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6    Dazzi, F.7
  • 12
    • 0347600715 scopus 로고    scopus 로고
    • Immunomodulatory effects of fetal and adult mesenchymal stem cells
    • Le Blanc K. Immunomodulatory effects of fetal and adult mesenchymal stem cells. Cytotherapy 5 (2003) 485-489
    • (2003) Cytotherapy , vol.5 , pp. 485-489
    • Le Blanc, K.1
  • 14
    • 0042740515 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex
    • Le Blanc K., Tammik L., Sundberg B., Haynesworth S.E., and Ringden O. Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complex. Scand. J. Immunol. 57 (2003) 11-20
    • (2003) Scand. J. Immunol. , vol.57 , pp. 11-20
    • Le Blanc, K.1    Tammik, L.2    Sundberg, B.3    Haynesworth, S.E.4    Ringden, O.5
  • 15
    • 4344683220 scopus 로고    scopus 로고
    • Mesenchymal stem cell inhibit the expression of CD25 (IL-2 receptor) and CD38 on pythohaemagglutinin activated lymphocyes
    • Le Blanc K., Gotherstrom C., and Rasmusson I. Mesenchymal stem cell inhibit the expression of CD25 (IL-2 receptor) and CD38 on pythohaemagglutinin activated lymphocyes. Scand. J. Immunol. (2004) 307-315
    • (2004) Scand. J. Immunol. , pp. 307-315
    • Le Blanc, K.1    Gotherstrom, C.2    Rasmusson, I.3
  • 16
    • 22144473736 scopus 로고    scopus 로고
    • Human mesenchymal stem cells require monocytes mediated activation to suppress alloreactive T cells
    • Margaret Eg., Basabi M., Emese S., and Omer N.K. Human mesenchymal stem cells require monocytes mediated activation to suppress alloreactive T cells. Exp. Hematol. (2005) 928-934
    • (2005) Exp. Hematol. , pp. 928-934
    • Margaret, Eg.1    Basabi, M.2    Emese, S.3    Omer, N.K.4
  • 17
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • Aggarwal S., and Pittenger M.F. Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105 (2005) 1815-1822
    • (2005) Blood , vol.105 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 18
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • Rasmusson I., Ringden O., Sundberg B., and Le Blanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 76 (2003) 1208-1213
    • (2003) Transplantation , vol.76 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 19
    • 17844391825 scopus 로고    scopus 로고
    • Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype
    • Maccario R., Podesta M., Moretta A., Cometa A., Comoli P., Montagna D., Daudt L., Ibatici A., Piaggio G., Pozzi S., et al. Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype. Haematologica 90 (2005) 516-525
    • (2005) Haematologica , vol.90 , pp. 516-525
    • Maccario, R.1    Podesta, M.2    Moretta, A.3    Cometa, A.4    Comoli, P.5    Montagna, D.6    Daudt, L.7    Ibatici, A.8    Piaggio, G.9    Pozzi, S.10
  • 20
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • Glennie S., Soeiro I., Dyson P.J., Lam E.W.F., and Dazzi F. Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood 105 (2005) 2821-2827
    • (2005) Blood , vol.105 , pp. 2821-2827
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.F.4    Dazzi, F.5
  • 24
    • 14644387445 scopus 로고    scopus 로고
    • CD69 is an immunoregulatory molecule induced following activation
    • Sancho D., Gomez M., and Sanchez-Madrid F. CD69 is an immunoregulatory molecule induced following activation. Trends Immunol. 26 (2005) 136-140
    • (2005) Trends Immunol. , vol.26 , pp. 136-140
    • Sancho, D.1    Gomez, M.2    Sanchez-Madrid, F.3
  • 27
    • 0036050976 scopus 로고    scopus 로고
    • Treatment of hight risk acute myelogenous leukaemia by myeloblative chemotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cell from a related donor with one fully mismatched human leucocytes antigen haplotype
    • Seung Tae L., Joon Ho J., June-Won C., Jin Seok K., Ho-Young M., Jee Sook H., Yun Woong K., and You S. Treatment of hight risk acute myelogenous leukaemia by myeloblative chemotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cell from a related donor with one fully mismatched human leucocytes antigen haplotype. Br. J. Haematol. (2002) 1128-1131
    • (2002) Br. J. Haematol. , pp. 1128-1131
    • Seung Tae, L.1    Joon Ho, J.2    June-Won, C.3    Jin Seok, K.4    Ho-Young, M.5    Jee Sook, H.6    Yun Woong, K.7    You, S.8
  • 28
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K., Rasmusson I., Sundberg B., Gotherstrom C., Hassan M., Uzunel M., and Ringden O. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363 (2004) 1439-1441
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Gotherstrom, C.4    Hassan, M.5    Uzunel, M.6    Ringden, O.7
  • 29
    • 12744274892 scopus 로고    scopus 로고
    • Adoptive immunotherapy for EBV-associated malignancies
    • Gottschalk S., Heslop H.E., and Rooney C.M. Adoptive immunotherapy for EBV-associated malignancies. Leuk. Lymphoma 46 (2005) 1-10
    • (2005) Leuk. Lymphoma , vol.46 , pp. 1-10
    • Gottschalk, S.1    Heslop, H.E.2    Rooney, C.M.3
  • 30
    • 0033826799 scopus 로고    scopus 로고
    • Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia
    • Molldrem J.J., Lee P.P., Wang C., Felio K., Kantarjian H.M., Champlin R.E., and Davis M.M. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat. Med. 6 (2000) 1018-1023
    • (2000) Nat. Med. , vol.6 , pp. 1018-1023
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3    Felio, K.4    Kantarjian, H.M.5    Champlin, R.E.6    Davis, M.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.