Ligand of numb proteins LNX1p80 and LNX2 interact with the human glycoprotein CD8α and promote its ubiquitylation and endocytosis

Journal of Cell Science

Volumn 124, Issue 21, 2011, Pages 3545-3556

  D'Agostino, Massimo ^a   Tornillo, Giusy ^a   Caporaso, Maria Gabriella ^a   Barone, Maria Vittoria ^a   Ghigo, Eric ^b   Bonatti, Stefano ^a   Mottola, Giovanna ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b AIX MARSEILLE UNIVERSITÉ   (France)

Author keywords

CD8; E3 ligase; Endocytosis; LNX protein; Ubiquitylation

Indexed keywords

CD8ALPHA ANTIGEN; MESSENGER RNA; PROTEIN LNX1; PROTEIN LNX2; UNCLASSIFIED DRUG; VALINE;

ARTICLE; CELL ASSAY; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; ENDOCYTOSIS; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; PDZ DOMAIN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; T LYMPHOCYTE; UBIQUITINATION;

ANTIGENS, CD8; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; ENDOCYTOSIS; HUMANS; PDZ DOMAINS; PROTEIN BINDING; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 81355161233     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.081224     Document Type: Article

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