메뉴 건너뛰기




Volumn 9, Issue 4, 2012, Pages 319-327

Anemia and Iron deficiency in heart failure

Author keywords

Anemia; Erythropoietin stimulating agents; Heart failure; Intravenous iron; Iron deficiency

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; CARVEDILOL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; HEMOGLOBIN; IRON; METOPROLOL; VALSARTAN;

EID: 84872177889     PISSN: 15469530     EISSN: 15469549     Source Type: Journal    
DOI: 10.1007/s11897-012-0112-x     Document Type: Article
Times cited : (11)

References (78)
  • 1
    • 84855353573 scopus 로고    scopus 로고
    • Heart disease and stroke statistics -2012 update: A report from the american heart association
    • Roger VL, et al. Heart disease and stroke statistics -2012 update: a report from the American Heart Association. Circulation. 2012;125 (1):e2-e220.
    • (2012) Circulation. , vol.125 , Issue.1
    • Roger, V.L.1
  • 2
    • 0034128813 scopus 로고    scopus 로고
    • The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations
    • Silverberg DS, et al. The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations. J Am Coll Cardiol. 2000;35(7):1737-44.
    • (2000) J Am Coll Cardiol. , vol.35 , Issue.7 , pp. 1737-1734
    • Silverberg, D.S.1
  • 3
    • 0142186283 scopus 로고    scopus 로고
    • Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: Randomised, double-blind, placebo-controlled trial
    • Henke M, et al. Erythropoietin to treat head and neck cancer patients with anaemia undergoing radiotherapy: randomised, double-blind, placebo-controlled trial. Lancet. 2003;362(9392):1255-60.
    • (2003) Lancet. , vol.362 , Issue.9392 , pp. 1255-1250
    • Henke, M.1
  • 4
    • 24944454286 scopus 로고    scopus 로고
    • Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: A survival study
    • Leyland-Jones B, et al. Maintaining normal hemoglobin levels with epoetin alfa in mainly nonanemic patients with metastatic breast cancer receiving first-line chemotherapy: a survival study. J Clin Oncol. 2005;23(25):5960-72.
    • (2005) J Clin Oncol. , vol.23 , Issue.25 , pp. 5960-5962
    • Leyland-Jones, B.1
  • 5
    • 33750983605 scopus 로고    scopus 로고
    • Correction of anemia with epoetin alfa in chronic kidney disease
    • Singh AK, et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med. 2006;355(20):2085-98.
    • (2006) N Engl J Med. , vol.355 , Issue.20 , pp. 2085-2088
    • Singh, A.K.1
  • 6
    • 70949108082 scopus 로고    scopus 로고
    • A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease
    • Pfeffer MA, et al. A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. N Engl J Med. 2009;361(21):2019-32.
    • (2009) N Engl J Med. , vol.361 , Issue.21 , pp. 2019-2012
    • Pfeffer, M.A.1
  • 8
    • 33645094960 scopus 로고    scopus 로고
    • Clinical correlates and consequences of anemia in a broad spectrum of patients with heart failure: Results of the candesartan in heart failure: Assessment of reduction in mortality and morbidity (charm) program
    • O'Meara E, et al. Clinical correlates and consequences of anemia in a broad spectrum of patients with heart failure: results of the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) Program. Circulation. 2006;113 (7):986-94.
    • (2006) Circulation. , vol.113 , Issue.7 , pp. 986-984
    • O'Meara, E.1
  • 9
    • 64349107250 scopus 로고    scopus 로고
    • Prospective assessment of the occurrence of anemia in patients with heart failure: Results from the study of anemia in a heart failure population (stamina-hfp) registry
    • Adams Jr KF, et al. Prospective assessment of the occurrence of anemia in patients with heart failure: results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry. Am Heart J. 2009;157(5):926-32.
    • (2009) Am Heart J. , vol.157 , Issue.5 , pp. 926-922
    • Adams Jr., K.F.1
  • 10
    • 27644522338 scopus 로고    scopus 로고
    • Anemia and outcomes in patients with heart failure: A study from the national heart care project
    • Kosiborod M, et al. Anemia and outcomes in patients with heart failure: a study from the National Heart Care Project. Arch Intern Med. 2005;165(19):2237-44.
    • (2005) Arch Intern Med. , vol.165 , Issue.19 , pp. 2237-2234
    • Kosiborod, M.1
  • 11
    • 33745459564 scopus 로고    scopus 로고
    • Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: The anemia in chronic heart failure: Outcomes and resource utilization (anchor) study
    • Go AS, et al. Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: the Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study. Circulation. 2006;113(23):2713-23.
    • (2006) Circulation. , vol.113 , Issue.23 , pp. 2713-2713
    • Go, A.S.1
  • 12
    • 48549103362 scopus 로고    scopus 로고
    • Anemia and heart failure: A community study
    • Dunlay SM, et al. Anemia and heart failure: a community study. Am J Med. 2008;121(8):726-32.
    • (2008) Am J Med. , vol.121 , Issue.8 , pp. 726-722
    • Dunlay, S.M.1
  • 13
    • 77953598601 scopus 로고    scopus 로고
    • Epidemiology of anemia in heart failure
    • Tang WH, Yeo PS. Epidemiology of anemia in heart failure. Heart Fail Clin. 2010;6(3):271-8.
    • (2010) Heart Fail Clin. , vol.6 , Issue.3 , pp. 271-278
    • Tang, W.H.1    Yeo, P.S.2
  • 14
    • 49849088979 scopus 로고    scopus 로고
    • Anemia and mortality in heart failure patients a systematic review and meta-Analysis
    • Groenveld HF, et al. Anemia and mortality in heart failure patients a systematic review and meta-Analysis. J Am Coll Cardiol. 2008;52 (10):818-27.
    • (2008) J Am Coll Cardiol. , vol.52 , Issue.10 , pp. 818-817
    • Groenveld, H.F.1
  • 15
    • 33744996445 scopus 로고    scopus 로고
    • The prevalence, nature, and importance of hematologic abnormalities in heart failure
    • Berry C, et al. The prevalence, nature, and importance of hematologic abnormalities in heart failure. Am Heart J. 2006;151 (6):1313-21.
    • (2006) Am Heart J. , vol.151 , Issue.6 , pp. 1313-1311
    • Berry, C.1
  • 16
    • 38349101846 scopus 로고    scopus 로고
    • Evaluation and long-Term prognosis of new-onset, transient, and persistent anemia in ambulatory patients with chronic heart failure
    • Tang WH, et al. Evaluation and long-Term prognosis of new-onset, transient, and persistent anemia in ambulatory patients with chronic heart failure. J Am Coll Cardiol. 2008;51(5):569-76.
    • (2008) J Am Coll Cardiol. , vol.51 , Issue.5 , pp. 569-566
    • Tang, W.H.1
  • 17
    • 13244268473 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitor as a risk factor for the development of anemia, and the impact of incident anemia on mortality in patients with left ventricular dysfunction
    • DOI 10.1016/j.jacc.2004.10.038, PII S0735109704021345
    • Ishani A, et al. Angiotensin-converting enzyme inhibitor as a risk factor for the development of anemia, and the impact of incident anemia on mortality in patients with left ventricular dysfunction. J Am Coll Cardiol. 2005;45(3):391-9. (Pubitemid 40186790)
    • (2005) Journal of the American College of Cardiology , vol.45 , Issue.3 , pp. 391-399
    • Ishani, A.1    Weinhandl, E.2    Zhao, Z.3    Gilbertson, D.T.4    Collins, A.J.5    Yusuf, S.6    Herzog, C.A.7
  • 19
    • 77953578561 scopus 로고    scopus 로고
    • Outcomes associated with anemia in patients with heart failure
    • Salisbury AC, Kosiborod M. Outcomes associated with anemia in patients with heart failure. Heart Fail Clin. 2010;6(3):359-72.
    • (2010) Heart Fail Clin. , vol.6 , Issue.3 , pp. 359-352
    • Salisbury, A.C.1    Kosiborod, M.2
  • 20
    • 72149089881 scopus 로고    scopus 로고
    • Association of longitudinal measures of hemoglobin and outcomes after hospitalization for heart failure
    • Peterson PN, et al. Association of longitudinal measures of hemoglobin and outcomes after hospitalization for heart failure. Am Heart J. 2010;159(1):81-9.
    • (2010) Am Heart J. , vol.159 , Issue.1 , pp. 81-89
    • Peterson, P.N.1
  • 21
    • 84855969520 scopus 로고    scopus 로고
    • Baseline anemia is not a predictor of all-cause mortality in outpatients with advanced heart failure or severe renal dysfunction. Results from the norwegian heart failure registry
    • This registry of 4144 chronic heart failure patients demonstrated that anemia was strongly associated with increased mortality. Yet, the study identified two subpopulations of patients in whom anemia was not a predictor of allcause mortality
    • Waldum B, et al. Baseline anemia is not a predictor of all-cause mortality in outpatients with advanced heart failure or severe renal dysfunction. Results from the Norwegian Heart Failure Registry. J Am Coll Cardiol. 2012;59(4):371-8. This registry of 4144 chronic heart failure patients demonstrated that anemia was strongly associated with increased mortality. Yet, the study identified two subpopulations of patients in whom anemia was not a predictor of allcause mortality.
    • (2012) J Am Coll Cardiol. , vol.59 , Issue.4 , pp. 371-378
    • Waldum, B.1
  • 24
    • 37549048168 scopus 로고    scopus 로고
    • Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the optimize-hf registry)
    • Young JB, et al. Relation of low hemoglobin and anemia to morbidity and mortality in patients hospitalized with heart failure (insight from the OPTIMIZE-HF registry). Am J Cardiol. 2008;101(2):223-30.
    • (2008) Am J Cardiol. , vol.101 , Issue.2 , pp. 223-220
    • Young, J.B.1
  • 25
    • 77953679829 scopus 로고    scopus 로고
    • Pathophysiology of anemia in heart failure
    • Anand IS. Pathophysiology of anemia in heart failure. Heart Fail Clin. 2010;6(3):279-88.
    • (2010) Heart Fail Clin. , vol.6 , Issue.3 , pp. 279-278
    • Anand, I.S.1
  • 26
    • 77953603162 scopus 로고    scopus 로고
    • Molecular changes in myocardium in the course of anemia or iron deficiency
    • Jankowska EA, Ponikowski. Molecular changes in myocardium in the course of anemia or iron deficiency. Heart Fail Clin. 2010;6 (3):295-304.
    • (2010) Heart Fail Clin. , vol.6 , Issue.3 , pp. 295-290
    • Jankowska, E.A.P.1
  • 27
    • 77953572552 scopus 로고    scopus 로고
    • Mediators of anemia in chronic heart failure
    • Le Jemtel TH, Arain S. Mediators of anemia in chronic heart failure. Heart Fail Clin. 2010;6(3):289-93.
    • (2010) Heart Fail Clin. , vol.6 , Issue.3 , pp. 289-283
    • Le Jemtel, T.H.1    Arain, S.2
  • 28
    • 0032849961 scopus 로고    scopus 로고
    • Angiotensin ii increases erythropoietin production in healthy human volunteers
    • Freudenthaler SM, et al. Angiotensin II increases erythropoietin production in healthy human volunteers. Eur J Clin Invest. 1999;29(10):816-23.
    • (1999) Eur J Clin Invest. , vol.29 , Issue.10 , pp. 816-813
    • Freudenthaler, S.M.1
  • 30
    • 38449104275 scopus 로고    scopus 로고
    • Erythropoietin in chronic heart failure
    • Belonje AM, et al. Erythropoietin in chronic heart failure. Congest Heart Fail. 2007;13(5):289-92.
    • (2007) Congest Heart Fail. , vol.13 , Issue.5 , pp. 289-282
    • Belonje, A.M.1
  • 31
    • 74949094517 scopus 로고    scopus 로고
    • Endogenous erythropoietin and outcome in heart failure
    • Belonje AM, et al. Endogenous erythropoietin and outcome in heart failure. Circulation. 2010;121(2):245-51.
    • (2010) Circulation. , vol.121 , Issue.2 , pp. 245-241
    • Belonje, A.M.1
  • 33
    • 33645452371 scopus 로고    scopus 로고
    • Chronic hypoxia and tubulointerstitial injury: A final common pathway to end-stage renal failure
    • Nangaku M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol. 2006;17(1):17-25.
    • (2006) J Am Soc Nephrol. , vol.17 , Issue.1 , pp. 17-15
    • Nangaku, M.1
  • 34
    • 0030273548 scopus 로고    scopus 로고
    • Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension
    • Testa M, et al. Circulating levels of cytokines and their endogenous modulators in patients with mild to severe congestive heart failure due to coronary artery disease or hypertension. J Am Coll Cardiol. 1996;28(4):964-71.
    • (1996) J Am Coll Cardiol. , vol.28 , Issue.4 , pp. 964-961
    • Testa, M.1
  • 35
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2005;352(10):1011-23.
    • (2005) N Engl J Med. , vol.352 , Issue.10 , pp. 1011-1013
    • Weiss, G.1    Goodnough, L.T.2
  • 36
    • 0037458095 scopus 로고    scopus 로고
    • Anemia is common in heart failure and is associated with poor outcomes: Insights from a cohort of 12 065 patients with new-onset heart failure
    • DOI 10.1161/01.CIR.0000052622.51963.FC
    • Ezekowitz JA, McAlister FA, Armstrong PW. Anemia is common in heart failure and is associated with poor outcomes: insights from a cohort of 12 065 patients with new-onset heart failure. Circulation. 2003;107(2):223-5. (Pubitemid 36135214)
    • (2003) Circulation , vol.107 , Issue.2 , pp. 223-225
    • Ezekowitz, J.A.1    McAlister, F.A.2    Armstrong, P.W.3
  • 37
    • 80052862992 scopus 로고    scopus 로고
    • Disordered iron homeostasis in chronic heart failure: Prevalence, predictors, and relation to anemia, exercise capacity, and survival
    • This paper demonstrates how the use of three frequently available indices (TSAT, ferritin, and TIBC) permits the biochemically meaningful discrimination between absolute iron deficiency, functional iron deficiency (ACD), and coexisting absolute + functional iron deficiency
    • Okonko DO, et al. Disordered iron homeostasis in chronic heart failure: prevalence, predictors, and relation to anemia, exercise capacity, and survival. J Am Coll Cardiol. 2011;58(12):1241-51. This paper demonstrates how the use of three frequently available indices (TSAT, ferritin, and TIBC) permits the biochemically meaningful discrimination between absolute iron deficiency, functional iron deficiency (ACD), and coexisting absolute + functional iron deficiency.
    • (2011) J Am Coll Cardiol. , vol.58 , Issue.12 , pp. 1241-1241
    • Okonko, D.O.1
  • 39
    • 43749123844 scopus 로고    scopus 로고
    • Heart failure and anemia: Mechanisms and pathophysiology
    • Anand IS. Heart failure and anemia: mechanisms and pathophysiology. Heart Fail Rev. 2008;13(4):379-86.
    • (2008) Heart Fail Rev. , vol.13 , Issue.4 , pp. 379-376
    • Anand, I.S.1
  • 42
    • 0037458102 scopus 로고    scopus 로고
    • Hemodilution is common in patients with advanced heart failure
    • Androne AS, et al. Hemodilution is common in patients with advanced heart failure. Circulation. 2003;107(2):226-9.
    • (2003) Circulation. , vol.107 , Issue.2 , pp. 226-229
    • Androne, A.S.1
  • 43
    • 84856247556 scopus 로고    scopus 로고
    • Perspectives for the treatment of anemia in heart failure: Is there a role for vasopressin antagonists?
    • Marques JS. Perspectives for the treatment of anemia in heart failure: is there a role for vasopressin antagonists? Congest Heart Fail. 2012;18(1):1-3.
    • (2012) Congest Heart Fail. , vol.18 , Issue.1 , pp. 1-3
    • Marques, J.S.1
  • 44
    • 80052102921 scopus 로고    scopus 로고
    • Anemia and iron deficiency in heart failure: Mechanisms and therapeutic approaches
    • van Veldhuisen DJ, et al. Anemia and iron deficiency in heart failure: mechanisms and therapeutic approaches. Nat Rev Cardiol. 2011;8(9):485-93.
    • (2011) Nat Rev Cardiol. , vol.8 , Issue.9 , pp. 485-483
    • Van Veldhuisen, D.J.1
  • 45
    • 32844465284 scopus 로고    scopus 로고
    • A randomized, controlled trial comparing iv iron sucrose to oral iron in anemic patients with nondialysisdependent ckd
    • Van Wyck DB, et al. A randomized, controlled trial comparing IV iron sucrose to oral iron in anemic patients with nondialysisdependent CKD. Kidney Int. 2005;68(6):2846-56.
    • (2005) Kidney Int. , vol.68 , Issue.6 , pp. 2846-2846
    • Van Wyck, D.B.1
  • 46
    • 73349121650 scopus 로고    scopus 로고
    • Iron metabolism iron deficiency thrombocytosis and the cardiorenal anemia syndrome
    • Besarab A, Horl WH, Silverberg D. Iron metabolism, iron deficiency, thrombocytosis, and the cardiorenal anemia syndrome. Oncologist. 2009;14 Suppl 1:22-33.
    • (2009) Oncologist. , vol.14 , Issue.SUPPL. 1 , pp. 22-23
    • Besarab, A.1    Horl, W.H.2    Silverberg, D.3
  • 47
    • 67650766504 scopus 로고    scopus 로고
    • Erythropoietin treatment in patients with chronic heart failure: A meta-Analysis
    • van der Meer P, et al. Erythropoietin treatment in patients with chronic heart failure: a meta-Analysis. Heart. 2009;95(16):1309-14.
    • (2009) Heart. , vol.95 , Issue.16 , pp. 1309-1304
    • Van Der Meer, P.1
  • 48
    • 33751002326 scopus 로고    scopus 로고
    • Normalization of hemoglobin level in patients with chronic kidney disease and anemia
    • Drueke TB, et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med. 2006;355 (20):2071-84.
    • (2006) N Engl J Med. , vol.355 , Issue.20 , pp. 2071-2074
    • Drueke, T.B.1
  • 49
    • 74449085180 scopus 로고    scopus 로고
    • A secondary analysis of the choir trial shows that comorbid conditions differentially affect outcomes during anemia treatment
    • This secondary analysis of the CHOIR trial did not demonstrate an increased risk of adverse events for patients with a history of heart failure who were treated with the higher hemoglobin target of 13.5 g/l as compared to those with a target of 11.3 g/l
    • Szczech LA, et al. A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment. Kidney Int. 2010;77(3):239-46. This secondary analysis of the CHOIR trial did not demonstrate an increased risk of adverse events for patients with a history of heart failure who were treated with the higher hemoglobin target of 13.5 g/l as compared to those with a target of 11.3 g/l.
    • (2010) Kidney Int. , vol.77 , Issue.3 , pp. 239-236
    • Szczech, L.A.1
  • 50
    • 77955933927 scopus 로고    scopus 로고
    • Impact of erythropoiesis-stimulating agents on morbidity and mortality in patients with heart failure: An updated, post-Treat meta-Analysis
    • This meta-Analysis of ESA treatment trials that included the subroup of patients with heart failure in the TREAT trial demonstrated that ESAs had a neutral effect on heart failure outcomes
    • Desai A, et al. Impact of erythropoiesis-stimulating agents on morbidity and mortality in patients with heart failure: an updated, post-TREAT meta-Analysis. Eur J Heart Fail. 2010;12(9):936-42. This meta-Analysis of ESA treatment trials that included the subroup of patients with heart failure in the TREAT trial demonstrated that ESAs had a neutral effect on heart failure outcomes.
    • (2010) Eur J Heart Fail. , vol.12 , Issue.9 , pp. 936-932
    • Desai, A.1
  • 51
    • 41049115024 scopus 로고    scopus 로고
    • Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia
    • Ghali JK, et al. Randomized double-blind trial of darbepoetin alfa in patients with symptomatic heart failure and anemia. Circulation. 2008;117(4):526-35.
    • (2008) Circulation. , vol.117 , Issue.4 , pp. 526-525
    • Ghali, J.K.1
  • 52
    • 35248870765 scopus 로고    scopus 로고
    • Intravenous iron reduces nt-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency
    • Toblli JE, et al. Intravenous iron reduces NT-pro-brain natriuretic peptide in anemic patients with chronic heart failure and renal insufficiency. J Am Coll Cardiol. 2007;50(17):1657-65.
    • (2007) J Am Coll Cardiol. , vol.50 , Issue.17 , pp. 1657-1655
    • Toblli, J.E.1
  • 53
    • 37849053243 scopus 로고    scopus 로고
    • Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency ferric-hf: A randomized, controlled, observer-blinded trial
    • Okonko DO, et al. Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial. J Am Coll Cardiol. 2008;51(2):103-12.
    • (2008) J Am Coll Cardiol. , vol.51 , Issue.2 , pp. 103-102
    • Okonko, D.O.1
  • 54
    • 72449156527 scopus 로고    scopus 로고
    • Ferric carboxymaltose in patients with heart failure and iron deficiency
    • Anker SD, et al. Ferric carboxymaltose in patients with heart failure and iron deficiency. N Engl J Med. 2009;361(25):2436-48.
    • (2009) N Engl J Med. , vol.361 , Issue.25 , pp. 2436-2438
    • Anker, S.D.1
  • 55
    • 40449087690 scopus 로고    scopus 로고
    • The non-haematopoietic biological effects of erythropoietin
    • Arcasoy MO. The non-haematopoietic biological effects of erythropoietin. Br J Haematol. 2008;141(1):14-31.
    • (2008) Br J Haematol. , vol.141 , Issue.1 , pp. 14-11
    • Arcasoy, M.O.1
  • 56
    • 57349135281 scopus 로고    scopus 로고
    • Darbepoetin-Alpha prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure
    • Rastogi S, et al. Darbepoetin-Alpha prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure. Am J Physiol Heart Circ Physiol. 2008;295(6):H2475-82.
    • (2008) Am J Physiol Heart Circ Physiol. , vol.295 , Issue.6
    • Rastogi, S.1
  • 57
    • 80054105158 scopus 로고    scopus 로고
    • The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression
    • Hedley BD, Allan AL, Xenocostas A. The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression. Clin Cancer Res. 2011;17(20):6373-80.
    • (2011) Clin Cancer Res. , vol.17 , Issue.20 , pp. 6373-6370
    • Hedley, B.D.1    Allan, A.L.2    Xenocostas, A.3
  • 58
    • 84862783287 scopus 로고    scopus 로고
    • Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents
    • Tanaka T, Nangaku M. Recent advances and clinical application of erythropoietin and erythropoiesis-stimulating agents. Exp Cell Res. 2012.
    • (2012) Exp Cell Res.
    • Tanaka, T.1    Nangaku, M.2
  • 59
    • 85047691007 scopus 로고    scopus 로고
    • A novel protective effect of erythropoietin in the infarcted heart
    • Parsa CJ, et al. A novel protective effect of erythropoietin in the infarcted heart. J Clin Invest. 2003;112(7):999-1007.
    • (2003) J Clin Invest. , vol.112 , Issue.7 , pp. 999-990
    • Parsa, C.J.1
  • 60
    • 77956704796 scopus 로고    scopus 로고
    • Erythropoietic response and outcomes in kidney disease and type 2 diabetes
    • Solomon SD, et al. Erythropoietic response and outcomes in kidney disease and type 2 diabetes. N Engl J Med. 2010;363(12):1146-55.
    • (2010) N Engl J Med. , vol.363 , Issue.12 , pp. 1146-1145
    • Solomon, S.D.1
  • 61
    • 84859218749 scopus 로고    scopus 로고
    • Effects of erythropoietin receptors and erythropoiesisstimulating agents on disease progression in cancer
    • AaproM. et al. Effects of erythropoietin receptors and erythropoiesisstimulating agents on disease progression in cancer. Br J Cancer. 2012.
    • (2012) Br J Cancer.
    • Aapro, M.1
  • 62
    • 77952582859 scopus 로고    scopus 로고
    • Erythropoiesis stimulating agents, thrombosis and cancer
    • Barbera L, Thomas G. Erythropoiesis stimulating agents, thrombosis and cancer. Radiother Oncol. 2010;95(3):269-76.
    • (2010) Radiother Oncol. , vol.95 , Issue.3 , pp. 269-266
    • Barbera, L.1    Thomas, G.2
  • 63
    • 43749091242 scopus 로고    scopus 로고
    • The prevalence of anemia in chronic heart failure and its impact on the clinical outcomes
    • Tang YD, Katz SD. The prevalence of anemia in chronic heart failure and its impact on the clinical outcomes. Heart Fail Rev. 2008;13(4):387-92.
    • (2008) Heart Fail Rev. , vol.13 , Issue.4 , pp. 387-382
    • Tang, Y.D.1    Katz, S.D.2
  • 64
    • 67749103752 scopus 로고    scopus 로고
    • Design of the reduction of events with darbepoetin alfa in heart failure (red-hf): A phase iii, anaemia correction, morbidity-mortality trial
    • McMurray JJ, et al. Design of the Reduction of Events with Darbepoetin alfa in Heart Failure (RED-HF): a Phase III, anaemia correction, morbidity-mortality trial. Eur J Heart Fail. 2009;11 (8):795-801.
    • (2009) Eur J Heart Fail. , vol.11 , Issue.8 , pp. 795-790
    • McMurray, J.J.1
  • 65
    • 21344459065 scopus 로고    scopus 로고
    • Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarction
    • van der Meer P, et al. Erythropoietin induces neovascularization and improves cardiac function in rats with heart failure after myocardial infarction. J Am Coll Cardiol. 2005;46(1):125-33.
    • (2005) J Am Coll Cardiol. , vol.46 , Issue.1 , pp. 125-123
    • Van Der Meer, P.1
  • 66
    • 33745250458 scopus 로고    scopus 로고
    • Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs
    • Hirata A, et al. Erythropoietin enhances neovascularization of ischemic myocardium and improves left ventricular dysfunction after myocardial infarction in dogs. J Am Coll Cardiol. 2006;48(1):176-84.
    • (2006) J Am Coll Cardiol. , vol.48 , Issue.1 , pp. 176-174
    • Hirata, A.1
  • 67
    • 34548767764 scopus 로고    scopus 로고
    • Effects of beta-erythropoietin treatment on left ventricular remodeling, systolic function, and b-Type natriuretic peptide levels in patients with the cardiorenal anemia syndrome
    • e9-5
    • Palazzuoli A, et al. Effects of beta-erythropoietin treatment on left ventricular remodeling, systolic function, and B-Type natriuretic peptide levels in patients with the cardiorenal anemia syndrome. Am Heart J. 2007;154(4):645 e9-15.
    • (2007) Am Heart J. , vol.154 , Issue.4 , pp. 645
    • Palazzuoli, A.1
  • 68
    • 6944237300 scopus 로고    scopus 로고
    • Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor
    • Brines M, et al. Erythropoietin mediates tissue protection through an erythropoietin and common beta-subunit heteroreceptor. Proc Natl Acad Sci U S A. 2004;101(41):14907-12.
    • (2004) Proc Natl Acad Sci U S A. , vol.101 , Issue.41 , pp. 14907-14902
    • Brines, M.1
  • 69
    • 13844320400 scopus 로고    scopus 로고
    • A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury
    • Fiordaliso F, et al. A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia-reperfusion injury. Proc Natl Acad Sci U S A. 2005;102(6):2046-51.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , Issue.6 , pp. 2046-2041
    • Fiordaliso, F.1
  • 70
    • 43749089210 scopus 로고    scopus 로고
    • Anemia and chronic heart failure implications and treatment options
    • Anand IS. Anemia and chronic heart failure implications and treatment options. J Am Coll Cardiol. 2008;52(7):501-11.
    • (2008) J Am Coll Cardiol. , vol.52 , Issue.7 , pp. 501-501
    • Anand, I.S.1
  • 71
    • 77955453008 scopus 로고    scopus 로고
    • Iron deficiency: An ominous sign in patients with systolic chronic heart failure
    • Prevalence of iron deficiency in patients with heart failure is typically discussed in the context of anemia. To our knowledge, this is the first study to provide an estimate of the prevalence of iron deficiency in patients with chronic systolic heart failure with or without anemia. Iron deficiency, regardless of the anemia status was shown to be an independent predictor of adverse outcomes
    • Jankowska EA, et al. Iron deficiency: an ominous sign in patients with systolic chronic heart failure. Eur Heart J. 2010;31 (15):1872-80. Prevalence of iron deficiency in patients with heart failure is typically discussed in the context of anemia. To our knowledge, this is the first study to provide an estimate of the prevalence of iron deficiency in patients with chronic systolic heart failure with or without anemia. Iron deficiency, regardless of the anemia status was shown to be an independent predictor of adverse outcomes.
    • (2010) Eur Heart J. , vol.31 , Issue.15 , pp. 80
    • Jankowska, E.A.1
  • 72
    • 25144483332 scopus 로고    scopus 로고
    • Dietary iron deficiency induces ventricular dilation, mitochondrial ultrastructural aberrations and cytochrome c release: Involvement of nitric oxide synthase and protein tyrosine nitration
    • Dong F, et al. Dietary iron deficiency induces ventricular dilation, mitochondrial ultrastructural aberrations and cytochrome c release: involvement of nitric oxide synthase and protein tyrosine nitration. Clin Sci (Lond). 2005;109(3):277-86.
    • (2005) Clin Sci (Lond). , vol.109 , Issue.3 , pp. 277-276
    • Dong, F.1
  • 73
    • 0035370037 scopus 로고    scopus 로고
    • The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: A randomized controlled study
    • Silverberg DS, et al. The effect of correction of mild anemia in severe, resistant congestive heart failure using subcutaneous erythropoietin and intravenous iron: a randomized controlled study. J Am Coll Cardiol. 2001;37(7):1775-80.
    • (2001) J Am Coll Cardiol. , vol.37 , Issue.7 , pp. 1775-1770
    • Silverberg, D.S.1
  • 74
    • 0037458127 scopus 로고    scopus 로고
    • Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure
    • DOI 10.1161/01.CIR.0000044914.42696.6A
    • Mancini DM, et al. Effect of erythropoietin on exercise capacity in patients with moderate to severe chronic heart failure. Circulation. 2003;107(2):294-9. (Pubitemid 36135227)
    • (2003) Circulation , vol.107 , Issue.2 , pp. 294-299
    • Mancini, D.M.1    Katz, S.D.2    Lang, C.C.3    LaManca, J.4    Hudaihed, A.5    Androne, A.-S.6
  • 75
    • 68249099779 scopus 로고    scopus 로고
    • Beta-erythropoietin effects on ventricular remodeling, left and right systolic function, pulmonary pressure, and hospitalizations in patients affected with heart failure and anemia
    • Palazzuoli A, et al. Beta-erythropoietin effects on ventricular remodeling, left and right systolic function, pulmonary pressure, and hospitalizations in patients affected with heart failure and anemia. J Cardiovasc Pharmacol. 2009;53(6):462-7.
    • (2009) J Cardiovasc Pharmacol. , vol.53 , Issue.6 , pp. 462-467
    • Palazzuoli, A.1
  • 76
    • 33846936320 scopus 로고    scopus 로고
    • Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: A randomized, double-blind, placebo-controlled trial
    • Ponikowski P, et al. Effect of darbepoetin alfa on exercise tolerance in anemic patients with symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled trial. J Am Coll Cardiol. 2007;49(7):753-62.
    • (2007) J Am Coll Cardiol. , vol.49 , Issue.7 , pp. 753-752
    • Ponikowski, P.1
  • 77
    • 34548798205 scopus 로고    scopus 로고
    • Randomized, double-blind, placebocontrolled study to evaluate the effect of two dosing regimens of darbepoetin alfa in patients with heart failure and anaemia
    • van Veldhuisen DJ, et al. Randomized, double-blind, placebocontrolled study to evaluate the effect of two dosing regimens of darbepoetin alfa in patients with heart failure and anaemia. Eur Heart J. 2007;28(18):2208-16.
    • (2007) Eur Heart J. , vol.28 , Issue.18 , pp. 2208-2206
    • Van Veldhuisen, D.J.1
  • 78
    • 40849133773 scopus 로고    scopus 로고
    • Effects of darbepoetin alpha on right and left ventricular systolic and diastolic function in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy
    • e1-7
    • Parissis JT, et al. Effects of darbepoetin alpha on right and left ventricular systolic and diastolic function in anemic patients with chronic heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am Heart J. 2008;155(4):751 e1-7.
    • (2008) Am Heart J. , vol.155 , Issue.4 , pp. 751
    • Parissis, J.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.