The prevalence of anemia in chronic heart failure and its impact on the clinical outcomes

Heart Failure Reviews

Volumn 13, Issue 4, 2008, Pages 387-392

  Tang, Yi Da ^a   Katz, Stuart D ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anemia in CHF prevalence; Prognosis

Indexed keywords

ERYTHROPOIETIN; LOSARTAN;

AGING; ANEMIA; CHRONIC KIDNEY DISEASE; CLINICAL TRIAL; COMORBIDITY; DISEASE COURSE; DISEASE SEVERITY; HEART FAILURE; HOSPITALIZATION; HUMAN; MORTALITY; PREDICTION; PREVALENCE; PROGNOSIS; REVIEW; RISK FACTOR;

ANEMIA; COMORBIDITY; HEART FAILURE; HUMANS; PREVALENCE; PROGNOSIS;

EID: 43749091242     PISSN: 13824147     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10741-008-9089-7     Document Type: Review

References (47)

1. Silverberg DS, Wexler D, Blum M et al (2000) The use of subcutaneous erythropoietin and intravenous iron for the treatment of the anemia of severe, resistant congestive heart failure improves cardiac and renal function and functional cardiac class, and markedly reduces hospitalizations. J Am Coll Cardiol 35(7):1737-1744
2. Tanner H, Moschovitis G, Kuster GM et al (2002) The prevalence of anemia in chronic heart failure. Int J Cardiol 86(1):115-121
3. Kalra PR, Bolger AP, Francis DP et al (2003) Effect of anemia on exercise tolerance in chronic heart failure in men. Am J Cardiol 91(7):888-891
4. Brucks S, Little WC, Chao T et al (2004) Relation of anemia to diastolic heart failure and the effect on outcome. Am J Cardiol 93(8):1055-1057
5. Ezekowitz JA, McAlister FA, Armstrong PW (2005) The interaction among sex, hemoglobin and outcomes in a specialty heart failure clinic. Can J Cardiol 21(2):165-171
6. Maggioni AP, Opasich C, Anand I et al (2005) Anemia in patients with heart failure: Prevalence and prognostic role in a controlled trial and in clinical practice. J Card Fail 11(2):91-98
7. Colin-Ramirez E, Castillo-Martinez L, Orea-Tejeda A et al (2006) Body composition and echocardiographic abnormalities associated to anemia and volume overload in heart failure patients. Clin Nutr 25(5):746-757
8. Go AS, Yang J, Ackerson LM et al (2006) Hemoglobin level, chronic kidney disease, and the risks of death and hospitalization in adults with chronic heart failure: The Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study. Circulation 113(23):2713-2723
9. de Silva R, Rigby AS, Witte KK et al (2006) Anemia, renal dysfunction, and their interaction in patients with chronic heart failure. Am J Cardiol 98(3):391-398
10. Westenbrink BD, Visser FW, Voors AA et al (2007) Anaemia in chronic heart failure is not only related to impaired renal perfusion and blunted erythropoietin production, but to fluid retention as well. Eur Heart J 28(2):166-171
11. Inglis SC, Stewart S, Papachan A et al (2007) Anaemia and renal function in heart failure due to idiopathic dilated cardiomyopathy. Eur J Heart Fail 9(4):384-390
12. Cromie N, Lee C, Struthers AD (2002) Anaemia in chronic heart failure: what is its frequency in the UK and its underlying causes? Heart 87(4):377-378
13. McClellan WM, Flanders WD, Langston RD et al (2002) Anemia and renal insufficiency are independent risk factors for death among patients with congestive heart failure admitted to community hospitals: A population-based study. J Am Soc Nephrol 13(7):1928-1936
14. Horwich TB, Fonarow GC, Hamilton MA et al (2002) Anemia is associated with worse symptoms, greater impairment in functional capacity and a significant increase in mortality in patients with advanced heart failure. J Am Coll Cardiol 39(11):1780-1786
15. Szachniewicz J, Petruk-Kowalczyk J, Majda J et al (2003) Anaemia is an independent predictor of poor outcome in patients with chronic heart failure. Int J Cardiol 90(2-3):303-308
16. Androne AS, Katz SD, Lund L et al (2003) Hemodilution is common in patients with advanced heart failure. Circulation 107(2):226-229
17. Ezekowitz JA, McAlister FA, Armstrong PW (2003) Anemia is common in heart failure and is associated with poor outcomes: Insights from a cohort of 12 065 patients with new-onset heart failure. Circulation 107(2):223-225
18. Kosiborod M, Smith GL, Radford MJ et al (2003) The prognostic importance of anemia in patients with heart failure. Am J Med 114(2):112-119
19. Nordyke RJ, Kim JJ, Goldberg GA et al (2004) Impact of anemia on hospitalization time, charges, and mortality in patients with heart failure. Value Health 7(4):464-471
20. Wexler D, Silverberg D, Sheps D et al (2004) Prevalence of anemia in patients admitted to hospital with a primary diagnosis of congestive heart failure. Int J Cardiol 96(1):79-87
21. Kosiborod M, Curtis JP, Wang Y et al (2005) Anemia and outcomes in patients with heart failure: A study from the National Heart Care Project. Arch Intern Med 165(19):2237-2244
22. Ceresa M, Capomolla S, Pinna G et al (2005) Anemia in chronic heart failure patients: Comparison between invasive and non-invasive prognostic markers. Monaldi Arch Chest Dis 64(2):124-133
23. Gardner RS, Chong KS, Morton JJ et al (2005) N-terminal brain natriuretic peptide, but not anemia, is a powerful predictor of mortality in advanced heart failure. J Card Fail 11(5 Suppl):S47-53
24. Maraldi C, Volpato S, Cesari M et al (2006) Anemia, physical disability, and survival in older patients with heart failure. J Card Fail 12(7):533-539
25. Newton JD, Squire IB (2006) Glucose and haemoglobin in the assessment of prognosis after first hospitalisation for heart failure. Heart 92(10):1441-1446
26. Sanchez-Torrijos J, Gudin-Uriel M, Nadal-Barange M et al (2006) Prognostic value of discharge hemoglobin level in patients hospitalized for acute heart failure. Rev Esp Cardiol 59(12):1276-1282
27. Grigorian Shamagian L, Varela Roman A, Garcia-Acuna JM et al (2006) Anaemia is associated with higher mortality among patients with heart failure with preserved systolic function. Heart 92(6):780-784
28. Berry C, Norrie J, Hogg K et al (2006) The prevalence, nature, and importance of hematologic abnormalities in heart failure. Am Heart J 151(6):1313-1321
29. Varadarajan P, Gandhi S, Sharma S et al (2006) Prognostic significance of hemoglobin level in patients with congestive heart failure and normal ejection fraction. Clin Cardiol 29(10):444-449
30. Silva RP, Barbosa PH, Kimura OS et al (2007) Prevalence of anemia and its association with cardio-renal syndrome. Int J Cardiol 120(2):232-236
31. Baggish AL, van Kimmenade R, Bayes-Genis A et al (2007) Hemoglobin and N-terminal pro-brain natriuretic peptide: Independent and synergistic predictors of mortality in patients with acute heart failure results from the International Collaborative of NT-proBNP (ICON) study. Clin Chim Acta 381(2):145-150
32. Al-Ahmad A, Rand WM, Manjunath G et al (2001) Reduced kidney function and anemia as risk factors for mortality in patients with left ventricular dysfunction. J Am Coll Cardiol 38(4):955-962
33. Mozaffarian D, Nye R, Levy WC (2003) Anemia predicts mortality in severe heart failure: The prospective randomized amlodipine survival evaluation (PRAISE). J Am Coll Cardiol 41(11):1933-1939
34. Felker GM, Gattis WA, Leimberger JD et al (2003) Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure. Am J Cardiol 92(5):625-628
35. Kalra PR, Collier T, Cowie MR et al (2003) Haemoglobin concentration and prognosis in new cases of heart failure. Lancet 362(9379):211-212
36. Sharma R, Francis DP, Pitt B et al (2004) Haemoglobin predicts survival in patients with chronic heart failure: A substudy of the ELITE II trial. Eur Heart J 25(12):1021-1028
37. Anand I, McMurray JJ, Whitmore J et al (2004) Anemia and its relationship to clinical outcome in heart failure. Circulation 110(2):149-154
38. Anand IS (2005) Pathogenesis of anemia in cardiorenal disease. Rev Cardiovasc Med 6(Suppl 3):S13-21
39. Ishani A, Weinhandl E, Zhao Z et al (2005) Angiotensin-converting enzyme inhibitor as a risk factor for the development of anemia, and the impact of incident anemia on mortality in patients with left ventricular dysfunction. J Am Coll Cardiol 45(3):391-399
40. O'Meara E, Clayton T, McEntegart MB et al (2006) Clinical correlates and consequences of anemia in a broad spectrum of patients with heart failure: Results of the Candesartan in Heart Failure: Assessment of Reduction in Mortality and Morbidity (CHARM) Program. Circulation 113(7):986-994
41. Komajda M, Anker SD, Charlesworth A et al (2006) The impact of new onset anaemia on morbidity and mortality in chronic heart failure: Results from COMET. Eur Heart J 27(12):1440-1446
42. Valeur N, Nielsen OW, McMurray JJ et al (2006) Anaemia is an independent predictor of mortality in patients with left ventricular systolic dysfunction following acute myocardial infarction. Eur J Heart Fail 8(6):577-584
43. Izaks GJ, Westendorp RG, Knook DL (1999) The definition of anemia in older persons. JAMA 281(18):1714-1717
44. IV. NKF-K/DOQI Clinical Practice Guidelines for Anemia of Chronic Kidney Disease: Update 2000 (2001). Am J Kidney Dis 37(1 Suppl 1):S182-238
45. Beutler E, Waalen J (2006) The definition of anemia: What is the lower limit of normal of the blood hemoglobin concentration? Blood 107(5):1747-1750
46. Gagnon DR, Zhang TJ, Brand FN et al (1994) Hematocrit and the risk of cardiovascular disease-the Framingham study: A 34-year follow-up. Am Heart J 127(3):674-682
47. Brown DW, Giles WH, Croft JB (2001) Hematocrit and the risk of coronary heart disease mortality. Am Heart J 142(4):657-663