-
1
-
-
33747151426
-
Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy
-
G.M. Alexander, and D.W. Godwin Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy Epilepsy. Res. 71 2006 1 22
-
(2006)
Epilepsy. Res.
, vol.71
, pp. 1-22
-
-
Alexander, G.M.1
Godwin, D.W.2
-
2
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 72 1976 248 254
-
(1976)
Anal. Biochem.
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
3
-
-
0029863890
-
Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies
-
S.R. Bradley, A.I. Levey, S.M. Hersch, and P.J. Conn Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies J. Neurosci. 16 1996 2044 2056
-
(1996)
J. Neurosci.
, vol.16
, pp. 2044-2056
-
-
Bradley, S.R.1
Levey, A.I.2
Hersch, S.M.3
Conn, P.J.4
-
5
-
-
0033842669
-
3H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat
-
3H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat Br. J. Pharmacol. 130 2000 1927 1932
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1927-1932
-
-
Chadha, A.1
Sur, C.2
Atack, J.3
Duty, S.4
-
6
-
-
0032402061
-
The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sites of glycinergic as well as GABAergic neurones
-
F.A. Chaudhry, R.J. Reimer, E.E. Bellocchio, N.C. Danbolt, K.K. Osen, R.H. Edwards, and J. Storm-Mathisen The vesicular GABA transporter, VGAT, localizes to synaptic vesicles in sites of glycinergic as well as GABAergic neurones J. Neurosci. 18 1998 9733 9750
-
(1998)
J. Neurosci.
, vol.18
, pp. 9733-9750
-
-
Chaudhry, F.A.1
Reimer, R.J.2
Bellocchio, E.E.3
Danbolt, N.C.4
Osen, K.K.5
Edwards, R.H.6
Storm-Mathisen, J.7
-
7
-
-
0030995878
-
Pharmacology and functions of metabotropic glutamate receptors
-
P.J. Conn, and J.P. Pin Pharmacology and functions of metabotropic glutamate receptors Annu. Rev. Pharmacol. Toxicol. 37 1997 205 237
-
(1997)
Annu. Rev. Pharmacol. Toxicol.
, vol.37
, pp. 205-237
-
-
Conn, P.J.1
Pin, J.P.2
-
8
-
-
2942642590
-
Automatic and quantitative measurement of protein-protein colocalization in live cells
-
S.V. Costes, D. Daelemans, E.H. Cho, Z. Dobbin, G. Pavlakis, and S. Lockett Automatic and quantitative measurement of protein-protein colocalization in live cells Biophys. J. 86 2004 3993 4003
-
(2004)
Biophys. J.
, vol.86
, pp. 3993-4003
-
-
Costes, S.V.1
Daelemans, D.2
Cho, E.H.3
Dobbin, Z.4
Pavlakis, G.5
Lockett, S.6
-
10
-
-
0028051718
-
Metabotropic glutamate receptor-induced disinhibition is mediated by reduced transmission at excitatory synapses onto interneurons and inhibitory synapses onto pyramidal cells
-
M.A. Desai, C.J. McBain, J.A. Kauer, and P.J. Conn Metabotropic glutamate receptor-induced disinhibition is mediated by reduced transmission at excitatory synapses onto interneurons and inhibitory synapses onto pyramidal cells Neurosci. Lett. 181 1994 78 82
-
(1994)
Neurosci. Lett.
, vol.181
, pp. 78-82
-
-
Desai, M.A.1
McBain, C.J.2
Kauer, J.A.3
Conn, P.J.4
-
11
-
-
0022531676
-
A rapid method for isolation of synaptosomes on Percoll gradients
-
P.R. Dunkley, P.E. Jarvie, J.W. Heath, G.J. Kidd, and J.A. Rostas A rapid method for isolation of synaptosomes on Percoll gradients Brain. Res. 372 1986 115 129
-
(1986)
Brain. Res.
, vol.372
, pp. 115-129
-
-
Dunkley, P.R.1
Jarvie, P.E.2
Heath, J.W.3
Kidd, G.J.4
Rostas, J.A.5
-
12
-
-
77954330278
-
Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease
-
S. Duty Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease Br. J. Pharmacol. 161 2010 271 287
-
(2010)
Br. J. Pharmacol.
, vol.161
, pp. 271-287
-
-
Duty, S.1
-
13
-
-
0028851850
-
Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1
-
R.W. Gereau 4th, and P.J. Conn Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1 J. Neurosci. 15 1995 6879 6889
-
(1995)
J. Neurosci.
, vol.15
, pp. 6879-6889
-
-
Gereau IV, R.W.1
Conn, P.J.2
-
14
-
-
1242306515
-
Somatostatin inhibits glutamate release from mouse cerebrocortical nerve endings trough presynaptic sst2 receptor linked to the adenylyl cyclase-protein kinase A pathway
-
M. Grilli, L. Raiteri, and A. Pittaluga Somatostatin inhibits glutamate release from mouse cerebrocortical nerve endings trough presynaptic sst2 receptor linked to the adenylyl cyclase-protein kinase A pathway Neuropharmacology 46 2004 388 396
-
(2004)
Neuropharmacology
, vol.46
, pp. 388-396
-
-
Grilli, M.1
Raiteri, L.2
Pittaluga, A.3
-
15
-
-
36849072696
-
N-methyl-D-Aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus
-
E. Luccini, V. Musante, E. Neri, M. Raiteri, and A. Pittaluga N-methyl-D-Aspartate autoreceptors respond to low and high agonist concentrations by facilitating, respectively, exocytosis and carrier-mediated release of glutamate in rat hippocampus J. Neurosci. Res. 85 2007 3657 3665
-
(2007)
J. Neurosci. Res.
, vol.85
, pp. 3657-3665
-
-
Luccini, E.1
Musante, V.2
Neri, E.3
Raiteri, M.4
Pittaluga, A.5
-
16
-
-
0027104001
-
Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy
-
E.M. Manders, J. Stap, G.J. Brakenhoff, R. van Driel, and J.A. Aten Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy J. Cell. Sci. 103 1992 857 862
-
(1992)
J. Cell. Sci.
, vol.103
, pp. 857-862
-
-
Manders, E.M.1
Stap, J.2
Brakenhoff, G.J.3
Van Driel, R.4
Aten, J.A.5
-
17
-
-
77953613109
-
Metabotropic glutamate2/3 (mGlu2/3) receptors, schizophrenia and cognition
-
G.J. Marek Metabotropic glutamate2/3 (mGlu2/3) receptors, schizophrenia and cognition Eur. J. Pharmacol. 639 2010 81 90
-
(2010)
Eur. J. Pharmacol.
, vol.639
, pp. 81-90
-
-
Marek, G.J.1
-
19
-
-
77952916153
-
The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocate Munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals
-
R. Martin, D. Durroux, F. Ciruela, M. Torres, J.P. Pin, and J. Sanchez-Prieto The metabotropic glutamate receptor mGlu7 activates phospholipase C, translocate Munc-13-1 protein, and potentiates glutamate release at cerebrocortical nerve terminals J. Biol. Chem. 285 2010 17907 17917
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 17907-17917
-
-
Martin, R.1
Durroux, D.2
Ciruela, F.3
Torres, M.4
Pin, J.P.5
Sanchez-Prieto, J.6
-
23
-
-
29444435620
-
A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo
-
K. Mitsukawa, R. Yamamoto, S. Ofner, J. Nozulak, O. Pescott, S. Lukic, N. Stoehr, C. Mombereau, R. Kuhn, K.H. McAllister, H. van der Putten, J.F. Cryan, and P.J. Flor A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo Proc. Natl. Acad. Sci. U S A 102 2005 18712 18717
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, pp. 18712-18717
-
-
Mitsukawa, K.1
Yamamoto, R.2
Ofner, S.3
Nozulak, J.4
Pescott, O.5
Lukic, S.6
Stoehr, N.7
Mombereau, C.8
Kuhn, R.9
McAllister, K.H.10
Van Der Putten, H.11
Cryan, J.F.12
Flor, P.J.13
-
24
-
-
79954614494
-
Metabotropic glutamate receptors: From the workbench to the bedside
-
F. Nicoletti, J. Bockaert, G.L. Collingridge, P.J. Conn, F. Ferraguti, D.D. Schoepp, J.T. Wroblewski, and J.P. Pin Metabotropic glutamate receptors: from the workbench to the bedside Neuropharmacology 60 2010 1017 1041
-
(2010)
Neuropharmacology
, vol.60
, pp. 1017-1041
-
-
Nicoletti, F.1
Bockaert, J.2
Collingridge, G.L.3
Conn, P.J.4
Ferraguti, F.5
Schoepp, D.D.6
Wroblewski, J.T.7
Pin, J.P.8
-
25
-
-
77949516412
-
Metabotropic glutamate receptors: Physiology, pharmacology and disease
-
C.M. Niswender, and P.J. Conn Metabotropic glutamate receptors: physiology, pharmacology and disease Annu. Rev. Pharmacol. Toxicol. 50 2010 295 322
-
(2010)
Annu. Rev. Pharmacol. Toxicol.
, vol.50
, pp. 295-322
-
-
Niswender, C.M.1
Conn, P.J.2
-
26
-
-
77956257563
-
The antidepressant-like action of metabotropic glutamate 7 receptor agonist N, N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent
-
A. Pałucha-Poniewiera, P. Brański, T. Lenda, and A. Pilc The antidepressant-like action of metabotropic glutamate 7 receptor agonist N, N'-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent J. Pharmacol. Exp. Ther. 334 2010 1066 1074
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.334
, pp. 1066-1074
-
-
Pałucha-Poniewiera, A.1
Brański, P.2
Lenda, T.3
Pilc, A.4
-
27
-
-
33845871976
-
MGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082
-
K. Pelkey, X. Yaun, G. Lavezzari, K.W. Roche, and C.J. Mc Bain mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082 Neuropharmacology 52 2007 108 117
-
(2007)
Neuropharmacology
, vol.52
, pp. 108-117
-
-
Pelkey, K.1
Yaun, X.2
Lavezzari, G.3
Roche, K.W.4
Mc Bain, C.J.5
-
28
-
-
0028912822
-
The metabotropic glutamate receptors: Structure and functions
-
J.P. Pin, and R. Duvoisin The metabotropic glutamate receptors: structure and functions Neuropharmacology 34 1995 1 26
-
(1995)
Neuropharmacology
, vol.34
, pp. 1-26
-
-
Pin, J.P.1
Duvoisin, R.2
-
29
-
-
0001050066
-
The metabotropic glutamate receptors: Structure, activation mechanism and pharmacology
-
J.P. Pin, and F. Ascher The metabotropic glutamate receptors: structure, activation mechanism and pharmacology Curr. Drug. Targets. CNS. Neurol. Disord. 1 2002 297 317
-
(2002)
Curr. Drug. Targets. CNS. Neurol. Disord.
, vol.1
, pp. 297-317
-
-
Pin, J.P.1
Ascher, F.2
-
31
-
-
0031007560
-
Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function
-
A. Pittaluga, A. Bonfanti, and M. Raiteri Differential desensitization of ionotropic non-NMDA receptors having distinct neuronal location and function Naunyn. Schmiedebergs. Arch. Pharmacol. 356 1997 29 38
-
(1997)
Naunyn. Schmiedebergs. Arch. Pharmacol.
, vol.356
, pp. 29-38
-
-
Pittaluga, A.1
Bonfanti, A.2
Raiteri, M.3
-
33
-
-
0034302965
-
Synaptosomes still viable after 25 years of superfusion
-
L. Raiteri, and M. Raiteri Synaptosomes still viable after 25 years of superfusion Neurochem. Res. 25 2000 1265 1274
-
(2000)
Neurochem. Res.
, vol.25
, pp. 1265-1274
-
-
Raiteri, L.1
Raiteri, M.2
-
34
-
-
0015944309
-
A simple apparatus for studying the release of neurotransmitters from synaptosomes
-
M. Raiteri, F. Angelini, and G. Levi A simple apparatus for studying the release of neurotransmitters from synaptosomes Eur. J. Pharmacol. 25 1974 411 414
-
(1974)
Eur. J. Pharmacol.
, vol.25
, pp. 411-414
-
-
Raiteri, M.1
Angelini, F.2
Levi, G.3
-
35
-
-
83455229501
-
The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signalling
-
S. Risso Bradley, J.M. Uslaner, R.B. Flick, A. Lee, K.M. Groover, and P.H. Huston The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signalling Pharmacol. Biochem. Behav. 101 2012 35 40
-
(2012)
Pharmacol. Biochem. Behav.
, vol.101
, pp. 35-40
-
-
Risso Bradley, S.1
Uslaner, J.M.2
Flick, R.B.3
Lee, A.4
Groover, K.M.5
Huston, P.H.6
-
36
-
-
0035890279
-
Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7
-
G. Sansig, T.J. Bushell, V.R. Clarke, A. Rozov, N. Burnashev, C. Portet, F. Gasparini, M. Schmutz, K. Klebs, R. Shigemoto, P.J. Flor, R. Kuhn, T. Knoepfel, M. Schroeder, D.R. Hampson, V.J. Collett, C. Zhang, R.M. Duvoisin, G.L. Collingridge, and H. van Der Putten Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 J. Neurosci. 21 2001 8734 8745
-
(2001)
J. Neurosci.
, vol.21
, pp. 8734-8745
-
-
Sansig, G.1
Bushell, T.J.2
Clarke, V.R.3
Rozov, A.4
Burnashev, N.5
Portet, C.6
Gasparini, F.7
Schmutz, M.8
Klebs, K.9
Shigemoto, R.10
Flor, P.J.11
Kuhn, R.12
Knoepfel, T.13
Schroeder, M.14
Hampson, D.R.15
Collett, V.J.16
Zhang, C.17
Duvoisin, R.M.18
Collingridge, G.L.19
Van Der Putten, H.20
more..
-
37
-
-
0034811597
-
Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system
-
D.D. Schoepp Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system J. Pharmacol. Exp. Ther. 299 2001 12 20
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.299
, pp. 12-20
-
-
Schoepp, D.D.1
-
38
-
-
0035906241
-
Presynaptic N-methyl-D-Aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals
-
S.M. Sequeira, J.O. Malva, A.P. Carvalho, and C.M. Carvalho Presynaptic N-methyl-D-Aspartate receptor activation inhibits neurotransmitter release through nitric oxide formation in rat hippocampal nerve terminals Mol. Brain. Res. 89 2001 111 118
-
(2001)
Mol. Brain. Res.
, vol.89
, pp. 111-118
-
-
Sequeira, S.M.1
Malva, J.O.2
Carvalho, A.P.3
Carvalho, C.M.4
-
39
-
-
0030821474
-
Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus
-
R. Shigemoto, A. Kinoshita, E. Wada, S. Nomura, H. Ohishi, M. Takada, P.J. Flor, A. Neki, T. Abe, S. Nakanishi, and N. Mizuno Differential presynaptic localization of metabotropic glutamate receptor subtypes in the rat hippocampus J. Neurosci. 17 1997 7503 7522
-
(1997)
J. Neurosci.
, vol.17
, pp. 7503-7522
-
-
Shigemoto, R.1
Kinoshita, A.2
Wada, E.3
Nomura, S.4
Ohishi, H.5
Takada, M.6
Flor, P.J.7
Neki, A.8
Abe, T.9
Nakanishi, S.10
Mizuno, N.11
-
41
-
-
0042868860
-
Insight into the function of group i and group II metabotropic glutamate (mGlu) receptors: Behavioural characterization and implications for the treatment of CNS disorders
-
W. Spooren, T. Ballard, F. Gasparini, M. Amalric, V. Mutel, and R. Schreiber Insight into the function of group I and group II metabotropic glutamate (mGlu) receptors: behavioural characterization and implications for the treatment of CNS disorders Behav. Pharmacol. 14 2003 257 277
-
(2003)
Behav. Pharmacol.
, vol.14
, pp. 257-277
-
-
Spooren, W.1
Ballard, T.2
Gasparini, F.3
Amalric, M.4
Mutel, V.5
Schreiber, R.6
-
42
-
-
79959527317
-
The metabotropic glutamate receptor 7 allosteric modulator AMN082: A monoaminergic agent in disguise?
-
S.J. Sukoff Rizzo, S.K. Leonard, A. Gilbert, P. Dollings, D.L. Smith, M.Y. Zhang, L. Di, B.J. Platt, S. Neal, J.M. Dwyer, C.N. Bender, J. Zhang, T. Lock, D. Kowal, A. Kramer, A. Randall, C. Huselton, K. Vishwanathan, S.Y. Tse, J. Butera, R.H. Ring, S. Rosenzweig-Lipson, Z.A. Hughes, and J. Dunlop The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise? J. Pharmacol. Exp. Ther. 338 2011 345 352
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.338
, pp. 345-352
-
-
Sukoff Rizzo, S.J.1
Leonard, S.K.2
Gilbert, A.3
Dollings, P.4
Smith, D.L.5
Zhang, M.Y.6
Di, L.7
Platt, B.J.8
Neal, S.9
Dwyer, J.M.10
Bender, C.N.11
Zhang, J.12
Lock, T.13
Kowal, D.14
Kramer, A.15
Randall, A.16
Huselton, C.17
Vishwanathan, K.18
Tse, S.Y.19
Butera, J.20
Ring, R.H.21
Rosenzweig-Lipson, S.22
Hughes, Z.A.23
Dunlop, J.24
more..
-
43
-
-
34548848868
-
In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists
-
G. Suzuki, N. Tsukamoto, H. Fushiki, A. Kawagishi, M. Nakamura, H. Kurihara, M. Mitsuya, M. Ohkubo, and H. Ohta In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists J. Pharmacol. Exp. Ther. 323 2007 147 156
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.323
, pp. 147-156
-
-
Suzuki, G.1
Tsukamoto, N.2
Fushiki, H.3
Kawagishi, A.4
Nakamura, M.5
Kurihara, H.6
Mitsuya, M.7
Ohkubo, M.8
Ohta, H.9
-
44
-
-
14044258729
-
Metabotropic glutamate receptors as novel targets for anxiety and stress disorders
-
C.J. Swanson, M. Bures, M.P. Johnson, A.M. Linden, J.A. Monn, and D.D. Schoepp Metabotropic glutamate receptors as novel targets for anxiety and stress disorders Nat. Rev. Drug. Discov. 4 2005 131 144
-
(2005)
Nat. Rev. Drug. Discov.
, vol.4
, pp. 131-144
-
-
Swanson, C.J.1
Bures, M.2
Johnson, M.P.3
Linden, A.M.4
Monn, J.A.5
Schoepp, D.D.6
-
45
-
-
64949091023
-
Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs
-
J.M. Wierońska, and A. Pilc Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs Neurochem. Int. 55 2009 85 97
-
(2009)
Neurochem. Int.
, vol.55
, pp. 85-97
-
-
Wierońska, J.M.1
Pilc, A.2
-
46
-
-
77952109021
-
GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and increased reelin proteins in the hippocampus
-
J.M. Wierońska, P. Brański, A. Siwek, M. Dybala, G. Nowak, and A. Pilc GABAergic dysfunction in mGlu7 receptor-deficient mice as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and increased reelin proteins in the hippocampus Brain. Res. 1334 2010 12 24
-
(2010)
Brain. Res.
, vol.1334
, pp. 12-24
-
-
Wierońska, J.M.1
Brański, P.2
Siwek, A.3
Dybala, M.4
Nowak, G.5
Pilc, A.6
-
48
-
-
77953210405
-
Synaptic and vesicular coexistence of VGLUT and VGAT in selected excitatory and inhibitory synapses
-
J.F. Zander, A. Münster-Wandowsky, I. Brunk, G. Gomez-Lira, U. Heinemann, R. Gutirrez, G. Laube, and G. Ahnert-Hilger Synaptic and vesicular coexistence of VGLUT and VGAT in selected excitatory and inhibitory synapses J. Neurosci. 30 2010 7634 7645
-
(2010)
J. Neurosci.
, vol.30
, pp. 7634-7645
-
-
Zander, J.F.1
Münster-Wandowsky, A.2
Brunk, I.3
Gomez-Lira, G.4
Heinemann, U.5
Gutirrez, R.6
Laube, G.7
Ahnert-Hilger, G.8
|