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Volumn 91, Issue 1, 2013, Pages 40-51

Anti-donor immune responses elicited by allogeneic mesenchymal stem cells: What have we learned so far

Author keywords

allogeneic; immune response; mesenchymal stem cells; T cells; transplant

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84872139846     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2012.67     Document Type: Review
Times cited : (208)

References (86)
  • 1
    • 0033932054 scopus 로고    scopus 로고
    • History of clinical transplantation
    • DOI 10.1007/s002680010124
    • Starzl T. History of clinical transplantation. World J Surg 2000; 24: 759-782. (Pubitemid 30437472)
    • (2000) World Journal of Surgery , vol.24 , Issue.7 , pp. 759-782
    • Starzl, T.E.1
  • 2
    • 0033768626 scopus 로고    scopus 로고
    • Transplantation and its biology: From fantasy to routine
    • Tilney NL. Transplantation and its biology: From fantasy to routine. J Appl Physiol 2000; 89: 1681-1689.
    • (2000) J Appl Physiol , vol.89 , pp. 1681-1689
    • Tilney, N.L.1
  • 3
    • 84655170198 scopus 로고    scopus 로고
    • Mechanisms of rejection: Current perspectives
    • Wood KJ, Goto R. Mechanisms of rejection: Current perspectives. Transplantation 2012; 93: 1-10.
    • (2012) Transplantation , vol.93 , pp. 1-10
    • Wood, K.J.1    Goto, R.2
  • 4
    • 77957734604 scopus 로고    scopus 로고
    • Rejection of the kidney allograft
    • Nankivell BJ, Alexander SI. Rejection of the kidney allograft. N Engl JMed 2010; 363: 1451-1462.
    • (2010) N Engl JMed , vol.363 , pp. 1451-1462
    • Nankivell, B.J.1    Alexander, S.I.2
  • 5
    • 84861553237 scopus 로고    scopus 로고
    • The impact of infection and tissue damage in solid-organ transplantation
    • Chong AS, Alegre M-L. The impact of infection and tissue damage in solid-organ transplantation. Nat Rev Immunol 2012; 12: 459-471.
    • (2012) Nat Rev Immunol , vol.12 , pp. 459-471
    • Chong, A.S.1    Alegre, M.-L.2
  • 7
    • 84863229939 scopus 로고    scopus 로고
    • Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation
    • Leventhal J, Abecassis M, Miller J, Gallon L, Ravindra K, Tollerud DJ et al. Chimerism and tolerance without GVHD or engraftment syndrome in HLA-mismatched combined kidney and hematopoietic stem cell transplantation. Science Transl Med 2012; 4: 124-128.
    • (2012) Science Transl Med , vol.4 , pp. 124-128
    • Leventhal, J.1    Abecassis, M.2    Miller, J.3    Gallon, L.4    Ravindra, K.5    Tollerud, D.J.6
  • 8
    • 68049127805 scopus 로고    scopus 로고
    • Monitoring and treating posttransplant human leukocyte antigen antibodies
    • Everly MJ, Terasaki PI. Monitoring and treating posttransplant human leukocyte antigen antibodies. Hum Immunol 2009; 70: 655-659.
    • (2009) Hum Immunol , vol.70 , pp. 655-659
    • Everly, M.J.1    Terasaki, P.I.2
  • 9
    • 47249158959 scopus 로고    scopus 로고
    • The spectrum of antibody-mediated renal allograft injury: Implications for treatment
    • DOI 10.1111/j.1600-6143.2008.02262.x
    • Gloor J, Cosio F, Lager DJ, Stegall MD. The spectrum of antibody-mediated renal allograft injury: Implications for treatment. Am J Transplant 2008; 8: 1367-1373. (Pubitemid 351989489)
    • (2008) American Journal of Transplantation , vol.8 , Issue.7 , pp. 1367-1373
    • Gloor, J.1    Cosio, F.2    Lager, D.J.3    Stegall, M.D.4
  • 10
    • 23844501054 scopus 로고    scopus 로고
    • Stem cells
    • DOI 10.1016/S0140-6736(05)66879-1, PII S0140673605668791
    • Vats A, Bielby RC, Tolley NS, Nerem R, Polak JM. Stem cells. Lancet 2005; 366: 592-602. (Pubitemid 41149084)
    • (2005) Lancet , vol.366 , Issue.9485 , pp. 592-602
    • Vats, A.1    Bielby, R.C.2    Tolley, N.S.3    Nerem, R.4    Polak, J.M.5
  • 11
    • 84856007232 scopus 로고    scopus 로고
    • The promise of induced pluripotent stem cells in research and therapy
    • Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature 2012; 481: 295-305.
    • (2012) Nature , vol.481 , pp. 295-305
    • Robinton, D.A.1    Daley, G.Q.2
  • 12
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008; 8: 726-736.
    • (2008) Nat Rev Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 13
    • 78649374199 scopus 로고    scopus 로고
    • Immunological aspects of allogeneic mesenchymal stem cell therapy
    • Griffin MD, Ritter T, Mahon B. Immunological aspects of allogeneic mesenchymal stem cell therapy. Hum Gene Ther 2010; 21: 1641-1655.
    • (2010) Hum Gene Ther , vol.21 , pp. 1641-1655
    • Griffin, M.D.1    Ritter, T.2    Mahon, B.3
  • 15
    • 77952319188 scopus 로고    scopus 로고
    • Mesenchymal stem cell therapy: Two steps forward, one step back
    • Ankrum J, Karp JM. Mesenchymal stem cell therapy: Two steps forward, one step back. Trends Mol Med 2010; 16: 203-209.
    • (2010) Trends Mol Med , vol.16 , pp. 203-209
    • Ankrum, J.1    Karp, J.M.2
  • 16
    • 58449135981 scopus 로고    scopus 로고
    • Why are MSCs therapeutic? New data: New insight
    • Caplan AI. Why are MSCs therapeutic? New data: New insight. J Pathol 2009; 217: 318-324.
    • (2009) J Pathol , vol.217 , pp. 318-324
    • Caplan, A.I.1
  • 17
    • 84866859990 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: A key player in 'innate tolerance'?
    • Dazzi F, Lopes L, Weng L. Mesenchymal stromal cells: A key player in 'innate tolerance'? Immunology 2012; 137: 206-213.
    • (2012) Immunology , vol.137 , pp. 206-213
    • Dazzi, F.1    Lopes, L.2    Weng, L.3
  • 18
    • 36348977575 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells
    • DOI 10.1182/blood-2007-02-069716
    • Nauta AJ, Fibbe WE. Immunomodulatory properties of mesenchymal stromal cells. Blood 2007; 110: 3499-3506. (Pubitemid 350159613)
    • (2007) Blood , vol.110 , Issue.10 , pp. 3499-3506
    • Nauta, A.J.1    Fibbe, W.E.2
  • 19
    • 84856973179 scopus 로고    scopus 로고
    • Mesenchymal stem/stromal sells (MSCs): Role as guardians of inflammation
    • Prockop DJ, Youn Oh J. Mesenchymal stem/stromal sells (MSCs): Role as guardians of inflammation. Mol Ther 2012; 20: 14-20.
    • (2012) Mol Ther , vol.20 , pp. 14-20
    • Prockop, D.J.1    Youn Oh, J.2
  • 20
    • 77956620353 scopus 로고    scopus 로고
    • Pharma's developing interest in stem cells
    • McKernan R, McNeish J, Smith D. Pharma's developing interest in stem cells. Cell Stem Cell 2010; 6: 517-520.
    • (2010) Cell Stem Cell , vol.6 , pp. 517-520
    • McKernan, R.1    McNeish, J.2    Smith, D.3
  • 21
    • 77957338676 scopus 로고    scopus 로고
    • Mesenchymal stromal cells: Facilitators of successful transplantation?
    • English K, French A, Wood KJ. Mesenchymal stromal cells: Facilitators of successful transplantation? Cell Stem Cell 2010; 7: 431-442.
    • (2010) Cell Stem Cell , vol.7 , pp. 431-442
    • English, K.1    French, A.2    Wood, K.J.3
  • 23
    • 49149111236 scopus 로고    scopus 로고
    • Exosomes as a short-range mechanism to spread alloantigen between dendritic cells during T cell allorecognition
    • Montecalvo A, Shufesky WJ, Beer Stolz D, Sullivan MG, Wang Z, Divito SJ et al. Exosomes as a short-range mechanism to spread alloantigen between dendritic cells during T cell allorecognition. J Immunol 2008; 180: 3081-3090.
    • (2008) J Immunol , vol.180 , pp. 3081-3090
    • Montecalvo, A.1    Shufesky, W.J.2    Beer Stolz, D.3    Sullivan, M.G.4    Wang, Z.5    Divito, S.J.6
  • 24
    • 80053221596 scopus 로고    scopus 로고
    • Pretreatment with interferon-gamma enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis
    • Duijvestein M, Wildenberg ME, Welling MM, Hennink S, Molendijk I, van Zuylen VL et al. Pretreatment with interferon-gamma enhances the therapeutic activity of mesenchymal stromal cells in animal models of colitis. Stem Cells 2011; 29: 1549-1558.
    • (2011) Stem Cells , vol.29 , pp. 1549-1558
    • Duijvestein, M.1    Wildenberg, M.E.2    Welling, M.M.3    Hennink, S.4    Molendijk, I.5    Van Zuylen, V.L.6
  • 25
    • 34249662219 scopus 로고    scopus 로고
    • IFN-γ and TNF-α differentially regulate immunomodulation by murine mesenchymal stem cells
    • DOI 10.1016/j.imlet.2007.04.001, PII S0165247807000739
    • English K, Barry FP, Field-Corbett CP, Mahon BP. IFN-g and TNF-a differentially regulate immunomodulation by murine mesenchymal stem cells. Immunol Lett 2007; 110: 91-100. (Pubitemid 46830943)
    • (2007) Immunology Letters , vol.110 , Issue.2 , pp. 91-100
    • English, K.1    Barry, F.P.2    Field-Corbett, C.P.3    Mahon, B.P.4
  • 26
    • 49149120713 scopus 로고    scopus 로고
    • A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1
    • Sheng H, Wang Y, Jin Y, Zhang Q, Zhang Y, Wang L et al. A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res 2008; 18: 846-857.
    • (2008) Cell Res , vol.18 , pp. 846-857
    • Sheng, H.1    Wang, Y.2    Jin, Y.3    Zhang, Q.4    Zhang, Y.5    Wang, L.6
  • 27
    • 49649106257 scopus 로고    scopus 로고
    • IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease
    • Polchert D, Sobinsky J, Douglas G, Kidd M, Moadsiri A, Reina E et al. IFN-gamma activation of mesenchymal stem cells for treatment and prevention of graft versus host disease. Eur J Immunol 2008; 38: 1745-1755.
    • (2008) Eur J Immunol , vol.38 , pp. 1745-1755
    • Polchert, D.1    Sobinsky, J.2    Douglas, G.3    Kidd, M.4    Moadsiri, A.5    Reina, E.6
  • 28
    • 33947200410 scopus 로고    scopus 로고
    • Murine Bone Marrow Stromal Progenitor Cells Elicit an In Vivo Cellular and Humoral Alloimmune Response
    • DOI 10.1016/j.bbmt.2006.12.447, PII S1083879106013097
    • Badillo AT, Beggs KJ, Javazon EH, Tebbets JC, Flake AW. Murine bone marrow stromal progenitor cells elicit an in vivo cellular and humoral alloimmune response. Biol Blood Marrow Transplant 2007; 13: 412-422. (Pubitemid 46421896)
    • (2007) Biology of Blood and Marrow Transplantation , vol.13 , Issue.4 , pp. 412-422
    • Badillo, A.T.1    Beggs, K.J.2    Javazon, E.H.3    Tebbets, J.C.4    Flake, A.W.5
  • 30
    • 80053153051 scopus 로고    scopus 로고
    • Mesenchymal stem cell inhibition of T-helper 17 cell-differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor
    • Duffy MM, Pindjakova J, Hanley SA, McCarthy C, Weidhofer GA, Sweeney EM et al. Mesenchymal stem cell inhibition of T-helper 17 cell-differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor. Eur J Immunol 2011; 41: 2840-2851.
    • (2011) Eur J Immunol , vol.41 , pp. 2840-2851
    • Duffy, M.M.1    Pindjakova, J.2    Hanley, S.A.3    McCarthy, C.4    Weidhofer, G.A.5    Sweeney, E.M.6
  • 31
    • 77958467862 scopus 로고    scopus 로고
    • Immunosuppression by mesenchymal stem cells: Mechanisms and clinical applications
    • Ghannam S, Bouffi C, Djouad F, Jorgensen C, Noel D. Immunosuppression by mesenchymal stem cells: Mechanisms and clinical applications. Stem Cell Res Ther 2010; 1: 2.
    • (2010) Stem Cell Res Ther , vol.1 , pp. 2
    • Ghannam, S.1    Bouffi, C.2    Djouad, F.3    Jorgensen, C.4    Noel, D.5
  • 32
    • 79952042164 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells
    • Kavanagh H, Mahon BP. Allogeneic mesenchymal stem cells prevent allergic airway inflammation by inducing murine regulatory T cells. Allergy 2011; 66: 523-531.
    • (2011) Allergy , vol.66 , pp. 523-531
    • Kavanagh, H.1    Mahon, B.P.2
  • 33
    • 0242300602 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells
    • DOI 10.1097/01.TP.0000082540.43730.80
    • Rasmusson I, Ringdén O, Sundberg B, LeBlanc K. Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cells. Transplantation 2003; 76: 1208-1213. (Pubitemid 37339646)
    • (2003) Transplantation , vol.76 , Issue.8 , pp. 1208-1213
    • Rasmusson, I.1    Ringden, O.2    Sundberg, B.3    Le Blanc, K.4
  • 34
    • 4644232573 scopus 로고    scopus 로고
    • Human mesenchymal stem cells suppress induction of cytotoxic response to alloantigens
    • Selected Papers of the 3rd International Symposium on Mechanobiology of Cartilage and Chondrocyte
    • Angoulvant D, Clerc A, Benchalal S, Galambrun C, Farre A, Bertrand Y et al. Human mesenchymal stem cells suppress induction of cytotoxic response to alloantigens. Biorheology 2004; 41: 469-476. (Pubitemid 39277103)
    • (2004) Biorheology , vol.41 , Issue.3-4 , pp. 469-476
    • Angoulvant, D.1    Clerc, A.2    Benchalal, S.3    Galambrunc, C.4    Farre, A.5    Bertrand, Y.6    Eljaafari, A.7
  • 35
    • 37349075167 scopus 로고    scopus 로고
    • Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation
    • DOI 10.1016/j.imlet.2007.10.002, PII S016524780700257X
    • English K, Barry FP, Mahon BP. Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation. Immunol Lett 2008; 115: 50-58. (Pubitemid 350298590)
    • (2008) Immunology Letters , vol.115 , Issue.1 , pp. 50-58
    • English, K.1    Barry, F.P.2    Mahon, B.P.3
  • 38
    • 84858183288 scopus 로고    scopus 로고
    • Bi-directional exchange of membrane components occurs during co-culture of mesenchymal stem cells and nucleus pulposus cells
    • Strassburg S, Hodson NW, Hill PI, Richardson SM, Hoyland JA. Bi-directional exchange of membrane components occurs during co-culture of mesenchymal stem cells and nucleus pulposus cells. PLoS One 2012; 7: E33739.
    • (2012) PLoS One , vol.7
    • Strassburg, S.1    Hodson, N.W.2    Hill, P.I.3    Richardson, S.M.4    Hoyland, J.A.5
  • 39
    • 49149099603 scopus 로고    scopus 로고
    • The B-cell response to protein antigens in immunity and transplantation
    • Tarlinton DM, Batista F, Smith KGC. The B-cell response to protein antigens in immunity and transplantation. Transplantation 2008; 85: 1698-1704.
    • (2008) Transplantation , vol.85 , pp. 1698-1704
    • Tarlinton, D.M.1    Batista, F.2    Smith, K.G.C.3
  • 40
    • 65249180708 scopus 로고    scopus 로고
    • Mechanisms of alloantibody production in sensitized renal allograft recipients
    • Stegall MD, Dean PG, Gloor J. Mechanisms of alloantibody production in sensitized renal allograft recipients. Am J Transplant 2009; 9: 998-1005.
    • (2009) Am J Transplant , vol.9 , pp. 998-1005
    • Stegall, M.D.1    Dean, P.G.2    Gloor, J.3
  • 43
    • 33947593728 scopus 로고    scopus 로고
    • Mesenchymal stem cells stimulate antibody secretion in human B cells
    • DOI 10.1111/j.1365-3083.2007.01905.x
    • Rasmusson I, Le Blanc K, Sundberg B, Ringdén O. Mesenchymal stem cells stimulate antibody secretion in human B cells. Scand J Immunol 2007; 65: 336-343. (Pubitemid 46481102)
    • (2007) Scandinavian Journal of Immunology , vol.65 , Issue.4 , pp. 336-343
    • Rasmusson, I.1    Le Blanc, K.2    Sundberg, B.3    Ringden, O.4
  • 44
    • 79959662452 scopus 로고    scopus 로고
    • The role of natural killer cells in human solid organ and tissue transplantation
    • Villard J. The role of natural killer cells in human solid organ and tissue transplantation. J Innate Immunity 2011; 3: 395-402.
    • (2011) J Innate Immunity , vol.3 , pp. 395-402
    • Villard, J.1
  • 45
    • 77957230535 scopus 로고    scopus 로고
    • Current perspectives of natural killer cell education by MHC class I molecules
    • Hoglund P, Brodin P. Current perspectives of natural killer cell education by MHC class I molecules. Nat Rev Immunol 2010; 10: 724-734.
    • (2010) Nat Rev Immunol , vol.10 , pp. 724-734
    • Hoglund, P.1    Brodin, P.2
  • 46
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • DOI 10.1182/blood-2005-07-2775
    • Spaggiari GM, Capobianco A, Becchetti S, Mingari MC, Moretta L. Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation. Blood 2006; 107: 1484-1490. (Pubitemid 43242385)
    • (2006) Blood , vol.107 , Issue.4 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 49
    • 67649723480 scopus 로고    scopus 로고
    • Cellular immune response to intrastriatally implanted allogeneic bone marrow stromal cells in a rat model of Parkinson's disease
    • Camp D, Loeffler D, Farrah D, Borneman JN, LeWitt PA. Cellular immune response to intrastriatally implanted allogeneic bone marrow stromal cells in a rat model of Parkinson's disease. J Inflamm 2009; 6: 17.
    • (2009) J Inflamm , vol.6 , pp. 17
    • Camp, D.1    Loeffler, D.2    Farrah, D.3    Borneman, J.N.4    LeWitt, P.A.5
  • 50
    • 70349625785 scopus 로고    scopus 로고
    • Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice
    • Chen L, Tredget EE, Liu C, Wu Y. Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice. PLoS One 2009; 4: E7119.
    • (2009) PLoS One , vol.4
    • Chen, L.1    Tredget, E.E.2    Liu, C.3    Wu, Y.4
  • 51
    • 72849151523 scopus 로고    scopus 로고
    • Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells
    • Zangi L, Margalit R, Reich-Zeliger S, Bachar-Lustig E, Beilhack A, Negrin R et al. Direct imaging of immune rejection and memory induction by allogeneic mesenchymal stromal cells. Stem Cells 2009; 27: 2865-2874.
    • (2009) Stem Cells , vol.27 , pp. 2865-2874
    • Zangi, L.1    Margalit, R.2    Reich-Zeliger, S.3    Bachar-Lustig, E.4    Beilhack, A.5    Negrin, R.6
  • 52
    • 65349174487 scopus 로고    scopus 로고
    • Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury
    • Togel F, Cohen A, Zhang P, Yang Y, Hu Z, Westenfelder C. Autologous and allogeneic marrow stromal cells are safe and effective for the treatment of acute kidney injury. Stem Cells Dev 2009; 18: 475-485.
    • (2009) Stem Cells Dev , vol.18 , pp. 475-485
    • Togel, F.1    Cohen, A.2    Zhang, P.3    Yang, Y.4    Hu, Z.5    Westenfelder, C.6
  • 53
    • 33746514768 scopus 로고    scopus 로고
    • Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting
    • DOI 10.1182/blood-2005-11-011650
    • Nauta AJ, Westerhuis G, Kruisselbrink AB, Lurvink EG, Willemze R, Fibbe WE. Donor-derived mesenchymal stem cells are immunogenic in an allogeneic host and stimulate donor graft rejection in a nonmyeloablative setting. Blood 2006; 108: 2114-2120. (Pubitemid 44395028)
    • (2006) Blood , vol.108 , Issue.6 , pp. 2114-2120
    • Nauta, A.J.1    Westerhuis, G.2    Kruisselbrink, A.B.3    Lurvink, E.G.A.4    Willemze, R.5    Fibbe, W.E.6
  • 54
    • 70349883762 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis
    • Rafei M, Birman E, Forner K, Galipeau J. Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis. Mol Ther 2009; 17: 1799-1803.
    • (2009) Mol Ther , vol.17 , pp. 1799-1803
    • Rafei, M.1    Birman, E.2    Forner, K.3    Galipeau, J.4
  • 55
    • 78650686250 scopus 로고    scopus 로고
    • Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair/clinical perspective
    • Huang X-P, Sun Z, Miyagi Y, McDonald Kinkaid H, Zhang L, Weisl RD et al. Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair/clinical perspective. Circulation 2010; 122: 2419-2429.
    • (2010) Circulation , vol.122 , pp. 2419-2429
    • Huang, X.-P.1    Sun, Z.2    Miyagi, Y.3    McDonald Kinkaid, H.4    Zhang, L.5    Weisl, R.D.6
  • 56
    • 69549138471 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity
    • Quevedo HC, Hatzistergos KE, Oskouei BN, Feighenbaum GS, Rodriguez JE, Valdes D et al. Allogeneic mesenchymal stem cells restore cardiac function in chronic ischemic cardiomyopathy via trilineage differentiating capacity. Proc Natl Acad Sci USA 2009; 106: 14022-14027.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14022-14027
    • Quevedo, H.C.1    Hatzistergos, K.E.2    Oskouei, B.N.3    Feighenbaum, G.S.4    Rodriguez, J.E.5    Valdes, D.6
  • 57
    • 58149326737 scopus 로고    scopus 로고
    • Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production
    • Nemeth K, Leelahavanichkul A, Yuen PS, Mayer B, Parmelee A, Doi K et al. Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production. Nat Med 2009; 15: 42-49.
    • (2009) Nat Med , vol.15 , pp. 42-49
    • Nemeth, K.1    Leelahavanichkul, A.2    Yuen, P.S.3    Mayer, B.4    Parmelee, A.5    Doi, K.6
  • 59
    • 28844483809 scopus 로고    scopus 로고
    • Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice
    • DOI 10.1182/blood-2005-03-1004
    • Eliopoulos N, Stagg J, Lejeune L, Pommey S, Galipeau J. Allogeneic marrow stromal cells are immune rejected by MHC class I-and class II-mismatched recipient mice. Blood 2005; 106: 4057-4065. (Pubitemid 41775910)
    • (2005) Blood , vol.106 , Issue.13 , pp. 4057-4065
    • Eliopoulos, N.1    Stagg, J.2    Lejeune, L.3    Pommey, S.4    Galipeau, J.5
  • 60
    • 77956618495 scopus 로고    scopus 로고
    • Cell-dose-dependent increases in circulating levels of immune effector cells in rhesus macaques following intracranial injection of allogeneic MSCs
    • Isakova IA, Dufour J, Lanclos C, Bruhn J, Phinney DG. Cell-dose-dependent increases in circulating levels of immune effector cells in rhesus macaques following intracranial injection of allogeneic MSCs. Exp Hematol 2010; 38: 957-967.
    • (2010) Exp Hematol , vol.38 , pp. 957-967
    • Isakova, I.A.1    Dufour, J.2    Lanclos, C.3    Bruhn, J.4    Phinney, D.G.5
  • 61
    • 34147174435 scopus 로고    scopus 로고
    • Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo
    • DOI 10.1097/01.tp.0000258649.23081.a3, PII 0000789020070327000021
    • Poncelet AJ, Vercruysse J, Saliez A, Gianello P. Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo. Transplantation 2007; 83: 783-790. (Pubitemid 46569198)
    • (2007) Transplantation , vol.83 , Issue.6 , pp. 783-790
    • Poncelet, A.J.1    Vercruysse, J.2    Saliez, A.3    Gianello, P.4
  • 62
    • 84872164299 scopus 로고    scopus 로고
    • Detrimental effects of rat mesenchymal stromal cell pre-treatment in a model of acute kidney rejection
    • Seifert M, Stolk M, Polenz D, Volk HD. Detrimental effects of rat mesenchymal stromal cell pre-treatment in a model of acute kidney rejection. Front Immunol 2012; 3: 202.
    • (2012) Front Immunol , vol.3 , pp. 202
    • Seifert, M.1    Stolk, M.2    Polenz, D.3    Volk, H.D.4
  • 63
    • 67650932291 scopus 로고    scopus 로고
    • Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance
    • Ge W, Jiang J, Baroja ML, Arp J, Zassoko R, Liu W et al. Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance. Am J Transplant 2009; 9: 1760-1772.
    • (2009) Am J Transplant , vol.9 , pp. 1760-1772
    • Ge, W.1    Jiang, J.2    Baroja, M.L.3    Arp, J.4    Zassoko, R.5    Liu, W.6
  • 64
    • 78650827566 scopus 로고    scopus 로고
    • Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression
    • Ge W, Jiang J, Arp J, Liu W, Garcia B, Wang H. Regulatory T-cell generation and kidney allograft tolerance induced by mesenchymal stem cells associated with indoleamine 2,3-dioxygenase expression. Transplantation 2010; 90: 1312-1320.
    • (2010) Transplantation , vol.90 , pp. 1312-1320
    • Ge, W.1    Jiang, J.2    Arp, J.3    Liu, W.4    Garcia, B.5    Wang, H.6
  • 65
    • 84865578483 scopus 로고    scopus 로고
    • Localization of mesenchymal stromal cells dictates their immune or proinflammatory effects in kidney transplantation
    • Casiraghi F, Azzollini N, Todeschini M, Cavinato RA, Cassis P, Solini S et al. Localization of mesenchymal stromal cells dictates their immune or proinflammatory effects in kidney transplantation. Am J Transplant 2012; 12: 2373-2383.
    • (2012) Am J Transplant , vol.12 , pp. 2373-2383
    • Casiraghi, F.1    Azzollini, N.2    Todeschini, M.3    Cavinato, R.A.4    Cassis, P.5    Solini, S.6
  • 66
    • 56149110595 scopus 로고    scopus 로고
    • Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory t cells
    • Casiraghi F, Azzollini N, Cassis P, Imberti B, Morigi M, Cugini D et al. Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory t cells. J Immunol 2008; 181: 3933-3946.
    • (2008) J Immunol , vol.181 , pp. 3933-3946
    • Casiraghi, F.1    Azzollini, N.2    Cassis, P.3    Imberti, B.4    Morigi, M.5    Cugini, D.6
  • 67
    • 0037313473 scopus 로고    scopus 로고
    • The complementary roles of deletion and regulation in transplantation tolerance
    • DOI 10.1038/nri1002
    • Lechler RI, Garden OA, Turka LA. The complementary roles of deletion and regulation in transplantation tolerance. Nat Rev Immunol 2003; 3: 147-158. (Pubitemid 37328692)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.2 , pp. 147-158
    • Lechler, R.I.1    Garden, O.A.2    Turka, L.A.3
  • 68
    • 50549095803 scopus 로고    scopus 로고
    • Post-transplantation antibody monitoring and HLA antibody epitope identification
    • Cai J, Terasaki PI. Post-transplantation antibody monitoring and HLA antibody epitope identification. Curr Opin Immunol 2008; 20: 602-606.
    • (2008) Curr Opin Immunol , vol.20 , pp. 602-606
    • Cai, J.1    Terasaki, P.I.2
  • 69
    • 58149341592 scopus 로고    scopus 로고
    • Inhibition of humoral response to allogeneic porcine mesenchymal stem cell with 12 days of tacrolimus
    • Poncelet AJ, Nizet Y, Vercruysse J, Hiel AL, Saliez A, Gianello P. Inhibition of humoral response to allogeneic porcine mesenchymal stem cell with 12 days of tacrolimus. Transplantation 2008; 86: 1586-1595.
    • (2008) Transplantation , vol.86 , pp. 1586-1595
    • Poncelet, A.J.1    Nizet, Y.2    Vercruysse, J.3    Hiel, A.L.4    Saliez, A.5    Gianello, P.6
  • 72
    • 38649105374 scopus 로고    scopus 로고
    • Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide
    • DOI 10.1016/j.stem.2007.11.014, PII S1934590907003141
    • Ren G, Zhang L, Zhao X, Zhang L, Zhang J, Roberts AI et al. Mesenchymal stem cellmediated immunosuppression occurs via concerted action of chemokines and nitric oxide. Cell Stem Cell 2008; 2: 141-150. (Pubitemid 351181031)
    • (2008) Cell Stem Cell , vol.2 , Issue.2 , pp. 141-150
    • Ren, G.1    Zhang, L.2    Zhao, X.3    Xu, G.4    Zhang, Y.5    Roberts, A.I.6    Zhao, R.C.7    Shi, Y.8
  • 74
    • 80052487336 scopus 로고    scopus 로고
    • Mesenchymal stromal cell 'licensing': A multistep process
    • Krampera M. Mesenchymal stromal cell 'licensing': A multistep process. Leukemia 2011; 25: 1408-1414.
    • (2011) Leukemia , vol.25 , pp. 1408-1414
    • Krampera, M.1
  • 75
    • 53749106408 scopus 로고    scopus 로고
    • MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-g challenge
    • Chan WK, Lau AS, Li JC, Law HK, Lau YL, Chan GC. MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-g challenge. Exp Hematol 2008; 36: 1545-1555.
    • (2008) Exp Hematol , vol.36 , pp. 1545-1555
    • Chan, W.K.1    Lau, A.S.2    Li, J.C.3    Law, H.K.4    Lau, Y.L.5    Chan, G.C.6
  • 77
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • DOI 10.1161/01.RES.0000135902.99383.6f
    • Pittenger MF, Martin BJ. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 2004; 95: 9-20. (Pubitemid 38931831)
    • (2004) Circulation Research , vol.95 , Issue.1 , pp. 9-20
    • Pittenger, M.F.1    Martin, B.J.2
  • 78
    • 84859105553 scopus 로고    scopus 로고
    • Current trends in mesenchymal stem cell application in bone augmentation: A review of the literature
    • Khojasteh A, Behnia H, Dashti SG, Stevens M. Current trends in mesenchymal stem cell application in bone augmentation: A review of the literature. J Oral Maxillofacial Surg 2012; 70: 972-982.
    • (2012) J Oral Maxillofacial Surg , vol.70 , pp. 972-982
    • Khojasteh, A.1    Behnia, H.2    Dashti, S.G.3    Stevens, M.4
  • 79
    • 53749098532 scopus 로고    scopus 로고
    • In vivo survival and osteogenic differentiation of allogeneic rat bone marrow mesenchymal stem cells (MSCs)
    • Kotobuki N, Katsube Y, Katou Y, Tadokoro M, Hirose M, Ohgushi H. In vivo survival and osteogenic differentiation of allogeneic rat bone marrow mesenchymal stem cells (MSCs). Cell Transplant 2008; 17: 705-712.
    • (2008) Cell Transplant , vol.17 , pp. 705-712
    • Kotobuki, N.1    Katsube, Y.2    Katou, Y.3    Tadokoro, M.4    Hirose, M.5    Ohgushi, H.6
  • 80
    • 33644522374 scopus 로고    scopus 로고
    • The immunogenicity and immunomodulatory function of osteogenic cells differentiated from mesenchymal stem cells
    • Liu H, Kemeny DM, Heng BC, Ouyang HW, Melendez AJ, Cao T. The immunogenicity and immunomodulatory function of osteogenic cells differentiated from mesenchymal stem cells. J Immunol 2006; 176: 2864-2871.
    • (2006) J Immunol , vol.176 , pp. 2864-2871
    • Liu, H.1    Kemeny, D.M.2    Heng, B.C.3    Ouyang, H.W.4    Melendez, A.J.5    Cao, T.6
  • 81
    • 80053552289 scopus 로고    scopus 로고
    • Mesenchymal stem cells
    • Williams AR, Hare JM. Mesenchymal stem cells. Circ Res 2011; 109: 923-940.
    • (2011) Circ Res , vol.109 , pp. 923-940
    • Williams, A.R.1    Hare, J.M.2
  • 82
    • 22144475112 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium: Short- and long-term effects
    • DOI 10.1161/CIRCULATIONAHA.104.527937
    • Dai W, Hale SL, Martin BJ, Kuang JQ, Dow JS, Wold LE et al. Allogeneic mesenchymal stem cell transplantation in postinfarcted rat myocardium. Circulation 2005; 112: 214-223. (Pubitemid 40982304)
    • (2005) Circulation , vol.112 , Issue.2 , pp. 214-223
    • Dai, W.1    Hale, S.L.2    Martin, B.J.3    Kuang, J.-Q.4    Dow, J.S.5    Wold, L.E.6    Kloner, R.A.7
  • 83
    • 84857032992 scopus 로고    scopus 로고
    • Mesenchymal stromal cell therapy: A revolution in regenerative medicine
    • Bernardo ME, Pagliara D, Locatelli F. Mesenchymal stromal cell therapy: A revolution in regenerative medicine. Bone Marrow Transplant 2012; 47: 164-171.
    • (2012) Bone Marrow Transplant , vol.47 , pp. 164-171
    • Bernardo, M.E.1    Pagliara, D.2    Locatelli, F.3
  • 84
    • 84862219665 scopus 로고    scopus 로고
    • Clinical applications of mesenchymal stem cells
    • Wang S, Xuebin Q, Zhao R. Clinical applications of mesenchymal stem cells. J Hematol Oncol 2012; 5: 19.
    • (2012) J Hematol Oncol , vol.5 , pp. 19
    • Wang, S.1    Xuebin, Q.2    Zhao, R.3
  • 85
    • 70549103270 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (Prochymal) after acute myocardial infarction
    • Hare JM, Traverse JH, Henry TD, Dib N, Strumpf RK, Schulman SP et al. A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (Prochymal) after acute myocardial infarction. J Am Coll Cardiol 2009; 54: 2277-2286.
    • (2009) J Am Coll Cardiol , vol.54 , pp. 2277-2286
    • Hare, J.M.1    Traverse, J.H.2    Henry, T.D.3    Dib, N.4    Strumpf, R.K.5    Schulman, S.P.6
  • 86
    • 34249791487 scopus 로고    scopus 로고
    • Transfusion-related acute lung injury and leucocyte-reacting antibodies
    • DOI 10.1111/j.1423-0410.2007.00920.x
    • Zupanska B, Uhrynowska M, Michur H, Maslanka K, Zajko M. Transfusion-related acute lung injury and leucocyte-reacting antibodies. Vox Sang 2007; 93: 70-77. (Pubitemid 46850710)
    • (2007) Vox Sanguinis , vol.93 , Issue.1 , pp. 70-77
    • Zupanska, B.1    Uhrynowska, M.2    Michur, H.3    Maslanka, K.4    Zajko, M.5


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