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Volumn 37, Issue 1, 2013, Pages 135-139

The A-allele of the common FTO gene variant rs9939609 complicates weight maintenance in severe obese patients

Author keywords

FTO gene; rs9939609; weight loss; Weight maintenance; weight regain

Indexed keywords

HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

EID: 84872106824     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2012.14     Document Type: Article
Times cited : (28)

References (26)
  • 1
    • 19944428203 scopus 로고    scopus 로고
    • Systematic review: An evaluation of major commercial weight loss programs in the United States
    • Tsai AG, Wadden TA. Systematic review: an evaluation of major commercial weight loss programs in the United States. Ann Intern Med 2005; 142: 56-66.
    • (2005) Ann Intern Med , vol.142 , pp. 56-66
    • Tsai, A.G.1    Wadden, T.A.2
  • 3
    • 30544444525 scopus 로고    scopus 로고
    • New advances in the genetics of early onset obesity
    • Farooqi IS, O'Rahilly S. New advances in the genetics of early onset obesity. Int J Obes 2005; 29: 1149-1152.
    • (2005) Int J Obes , vol.29 , pp. 1149-1152
    • Farooqi, I.S.1    O'Rahilly, S.2
  • 4
    • 44349142294 scopus 로고    scopus 로고
    • Common variants near MC4R are associated with fat mass, weight and risk of obesity
    • Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I et al. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nature Genet 2008; 40: 768-775.
    • (2008) Nature Genet , vol.40 , pp. 768-775
    • Loos, R.J.1    Lindgren, C.M.2    Li, S.3    Wheeler, E.4    Zhao, J.H.5    Prokopenko, I.6
  • 5
  • 6
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM,Timpson NJ,Weedon MN, Zeggini E, Freathy RM, Lindgren CM etal. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3    Zeggini, E.4    Freathy, R.M.5    Lindgren, C.M.6
  • 7
    • 0036220971 scopus 로고    scopus 로고
    • The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster
    • Peters T, Ausmeier K, Dildrop R, Rüther U. The mouse Fused toes (Ft) mutation is the result of a 1.6-Mb deletion including the entire Iroquois B gene cluster. Mamm Genome 2002; 13: 186-188.
    • (2002) Mamm Genome , vol.13 , pp. 186-188
    • Peters, T.1    Ausmeier, K.2    Dildrop, R.3    Rüther, U.4
  • 8
    • 0032886705 scopus 로고    scopus 로고
    • Cloning of Fatso (Fto), a novel gene deleted by the Fused toe (Ft) mouse mutation
    • Peters T, Ausmeier K, Rüther U. Cloning of Fatso (Fto), a novel gene deleted by the Fused toe (Ft) mouse mutation. Mamm Genome 1999; 10: 983-986.
    • (1999) Mamm Genome , vol.10 , pp. 983-986
    • Peters, T.1    Ausmeier, K.2    Rüther, U.3
  • 9
    • 34249777814 scopus 로고    scopus 로고
    • Variation in FTO contributes to childhood obesity and severe adult obesity
    • Dina C, Meyre D, Gallina S, Durand E, Körner A, Jacobson P et al. Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007; 39: 724-726.
    • (2007) Nat Genet , vol.39 , pp. 724-726
    • Dina, C.1    Meyre, D.2    Gallina, S.3    Durand, E.4    Körner, A.5    Jacobson, P.6
  • 10
    • 36749041363 scopus 로고    scopus 로고
    • The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
    • Gerken T, Girard CA, Tung YCL, Webby CJ, Saudek V, Hewitson KS et al. The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007; 318: 1469-1472.
    • (2007) Science , vol.318 , pp. 1469-1472
    • Gerken, T.1    Girard, C.A.2    Ycl, T.3    Webby, C.J.4    Saudek, V.5    Hewitson, K.S.6
  • 11
    • 78649322992 scopus 로고    scopus 로고
    • FTO influences on longitudinal BMI over childhood and adulthood and modulation on relationship between birth weight and longitudinal BMI
    • Mei H, Chen W, Srinivasan SR, Jiang F, Schork N, Murray S et al. FTO influences on longitudinal BMI over childhood and adulthood and modulation on relationship between birth weight and longitudinal BMI. Hum Genet 2010; 128: 589-596.
    • (2010) Hum Genet , vol.128 , pp. 589-596
    • Mei, H.1    Chen, W.2    Srinivasan, S.R.3    Jiang, F.4    Schork, N.5    Murray, S.6
  • 12
    • 70450165135 scopus 로고    scopus 로고
    • A common variant of the FTO gene is associated with not only increased adiposity but also elevated blood pressure in French Canadians
    • Pausova Z, Syme C, Abrahamowicz M, Xiao Y, Leonard GT, Perron M etal. A common variant of the FTO gene is associated with not only increased adiposity but also elevated blood pressure in French Canadians. Circ Cardiovasc Genet 2009;2:260-269.
    • (2009) Circ Cardiovasc Genet , vol.2 , pp. 260-269
    • Pausova, Z.1    Syme, C.2    Abrahamowicz, M.3    Xiao, Y.4    Leonard, G.T.5    Perron, M.6
  • 13
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J et al. Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLo S Genetics 2007; 3: 1200-1210.
    • (2007) PLo S Genetics , vol.3 , pp. 1200-1210
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3    Uda, M.4    Albai, G.5    Strait, J.6
  • 14
    • 80052762427 scopus 로고    scopus 로고
    • Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - The Finnish Diabetes Prevention Study
    • Lappalainen T, Kolehmainen M, Schwab US, Tolppanen AM, Stanèáková A, Lindström J et al. Association of the FTO gene variant (rs9939609) with cardiovascular disease in men with abnormal glucose metabolism - the Finnish Diabetes Prevention Study. Nutr Metab Cardiovasc Dis 2011; 21: 691 -698.
    • (2011) Nutr Metab Cardiovasc Dis , vol.21 , pp. 691-698
    • Lappalainen, T.1    Kolehmainen, M.2    Schwab, U.S.3    Tolppanen, A.M.4    Stanèáková, A.5    Lindström, J.6
  • 15
    • 63049108553 scopus 로고    scopus 로고
    • The common variant in the FTO gene did not modify the effect of lifestyle changes on body weight: The Finnish Diabetes Prevention Study
    • Lappalainen TJ, Tolppanen AM, Kolehmainen M, Schwab U, Lindström J, Tuomilehto J et al. The common variant in the FTO gene did not modify the effect of lifestyle changes on body weight: the Finnish Diabetes Prevention Study. Obesity 2009; 17: 832-836.
    • (2009) Obesity , vol.17 , pp. 832-836
    • Lappalainen, T.J.1    Tolppanen, A.M.2    Kolehmainen, M.3    Schwab, U.4    Lindström, J.5    Tuomilehto, J.6
  • 16
    • 78649459183 scopus 로고    scopus 로고
    • Overexpression of Fto leads to increased food intake and results in obesity
    • Church C, Moir L, Mc Murray F, Girard C, Banks GT, Teboul L et al. Overexpression of Fto leads to increased food intake and results in obesity. Nat Genet 2010; 42: 1086-1092.
    • (2010) Nat Genet , vol.42 , pp. 1086-1092
    • Church, C.1    Moir, L.2    Mc Murray, F.3    Girard, C.4    Banks, G.T.5    Teboul, L.6
  • 17
    • 77955981202 scopus 로고    scopus 로고
    • The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels
    • Berulava T, Horsthemke B. The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur J Hum Genet 2010; 18: 1054-1056.
    • (2010) Eur J Hum Genet , vol.18 , pp. 1054-1056
    • Berulava, T.1    Horsthemke, B.2
  • 18
    • 48749132799 scopus 로고    scopus 로고
    • Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure
    • Speakman JR, Rance KA, Johnstone AM. Polymorphisms of the FTO gene are associated with variation in energy intake, but not energy expenditure. Obesity 2008; 16: 1961 -1965.
    • (2008) Obesity , vol.16 , pp. 1961-1965
    • Speakman, J.R.1    Rance, K.A.2    Johnstone, A.M.3
  • 22
    • 53049097172 scopus 로고    scopus 로고
    • Fat mass and obesity associated' gene (FTO): No significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents
    • Müller TD, Hinney A, Scherag A, Nguyen TT, Schreiner F, Schäfer H et al. Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents. BMC Med Genet 2008; 9:85.
    • (2008) BMC Med Genet , vol.9 , pp. 85
    • Müller, T.D.1    Hinney, A.2    Scherag, A.3    Nguyen, T.T.4    Schreiner, F.5    Schäfer, H.6
  • 23
    • 70450273183 scopus 로고    scopus 로고
    • Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans
    • Grau K, Hansen T, Holst C, Astrup A, Saris WH, Arner P et al. Macronutrient-specific effect of FTO rs9939609 in response to a 10-week randomized hypo-energetic diet among obese Europeans. Int J Obes 2009; 33: 1227-1234.
    • (2009) Int J Obes , vol.33 , pp. 1227-1234
    • Grau, K.1    Hansen, T.2    Holst, C.3    Astrup, A.4    Saris, W.H.5    Arner, P.6
  • 24
    • 84859637663 scopus 로고    scopus 로고
    • Multicenter evaluation of an interdisciplinary 52-week weight loss program for obesity with regard to body weight, comorbidities and quality of life - A prospective study
    • e-pub ahead of print 14 June 2011; doi: 10.1038/ijo.2011.107
    • Bischoff SC, Damms-Machado A, Betz C, Herpertz S, Legenbauer T, Löw T et al. Multicenter evaluation of an interdisciplinary 52-week weight loss program for obesity with regard to body weight, comorbidities and quality of life - a prospective study. Int J Obes 2011. e-pub ahead of print 14 June 2011; doi: 10.1038/ijo.2011.107.
    • (2011) Int J Obes
    • Bischoff, S.C.1    Damms-Machado, A.2    Betz, C.3    Herpertz, S.4    Legenbauer, T.5    Löw, T.6
  • 26
    • 84872104348 scopus 로고    scopus 로고
    • International Hap Map Project Internet
    • International Hap Map Project. Internet: http://hapmap.ncbi.nlm.nih.gov/.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.