Simulating intravitreal injections in anatomically accurate models for rabbit, monkey, and human eyes

Pharmaceutical Research

Volumn 29, Issue 12, 2012, Pages 3251-3272

  Missel, Paul J ^a  

^a ALCON RESEARCH LTD   (United States)

Author keywords

Computational Fluid Dynamics (CFD); Convective diffusion; Drug clearance; Intravitreal injection

Indexed keywords

ACCURACY; ARTICLE; BOLUS INJECTION; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DIFFUSION; DRUG UPTAKE; EYE; GEOMETRY; HUMAN; INTRAOCULAR PRESSURE; INTRAVITREAL DRUG ADMINISTRATION; MATHEMATICAL MODEL; MOLECULAR WEIGHT; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RABBIT; RHESUS MONKEY; SIMULATION; THERMODYNAMICS;

ANIMALS; COMPUTER SIMULATION; EYE; HAPLORHINI; HUMANS; HYDRODYNAMICS; INTRAVITREAL INJECTIONS; METABOLIC CLEARANCE RATE; MODELS, ANATOMIC; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RABBITS;

EID: 84872065953     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-012-0721-9     Document Type: Article

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