Simulating dissolution of intravitreal triamcinolone acetonide suspensions in an anatomically accurate rabbit eye model

Pharmaceutical Research

Volumn 27, Issue 8, 2010, Pages 1530-1546

  Missel, Paul J ^a   Horner, Marc ^b   Muralikrishnan, R ^c  

^a ALCON RESEARCH LTD   (United States)

^b ANSYS INC   (United States)

^c Fluent India Private Limited   (India)

Author keywords

computational fluid dynamics (CFD); convective diffusion; dissolution; drug clearance; intravitreal injection; volume of fluid (VOF)

Indexed keywords

TRIAMCINOLONE ACETONIDE; TRIESENCE; UNCLASSIFIED DRUG; SUSPENSION;

AQUEOUS HUMOR; ARTICLE; COMPUTATIONAL FLUID DYNAMICS; COMPUTER SIMULATION; CONTROLLED STUDY; DIFFUSION; DRUG CLEARANCE; DRUG RELEASE; DRUG SOLUBILITY; INTRAOCULAR PRESSURE; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PREDICTION; PRIORITY JOURNAL; RABBIT; SUSPENSION; ANIMAL; AUDIOVISUAL EQUIPMENT; CHEMISTRY; SOLUBILITY;

ANIMALS; COMPUTER SIMULATION; MODELS, ANATOMIC; PARTICLE SIZE; RABBITS; SOLUBILITY; SUSPENSIONS; TRIAMCINOLONE ACETONIDE;

EID: 77955472632     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0163-1     Document Type: Article

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