Evaluation of coupled convective-diffusive transport of drugs administered by intravitreal injection and controlled release implant

Journal of Controlled Release

Volumn 105, Issue 3, 2005, Pages 279-295

  Park, Juyoung ^a   Bungay, Peter M ^c   Lutz, Robert J ^c   Augsburger, James J ^b   Millard, Ronald W ^b   Roy, Abhijit Sinha ^a   Banerjee, Rupak K ^a  

^a University of Cincinnati   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Controlled release implant; Convective diffusive transport; Drug delivery; Drug distribution; Eye; Intravitreal injection

Indexed keywords

CONCENTRATION (PROCESS); DISEASES; DRUG PRODUCTS; FINITE ELEMENT METHOD; IMPLANTS (SURGICAL); MOLECULAR WEIGHT; PHARMACOKINETICS;

DRUG ADMINISTRATION; DRUG DISTRIBUTION; INTRAVITREAL INJECTION; RETINAL DISEASE;

CONTROLLED DRUG DELIVERY;

FLUORESCEIN;

ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG DIFFUSION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG SCREENING; DRUG TRANSPORT; FINITE ELEMENT ANALYSIS; FLUID FLOW; INJECTION; MOLECULAR MODEL; MOLECULAR WEIGHT; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RABBIT; RETINA DISEASE; SIMULATION; THERMODYNAMICS; THREE DIMENSIONAL IMAGING; VALIDATION PROCESS; VITREOUS BODY;

ALGORITHMS; ANIMALS; ANTERIOR EYE SEGMENT; AQUEOUS HUMOR; CHEMISTRY, PHYSICAL; DELAYED-ACTION PREPARATIONS; DRUG IMPLANTS; FINITE ELEMENT ANALYSIS; FLUORESCEIN; HALF-LIFE; INJECTIONS; KINETICS; MODELS, STATISTICAL; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; RABBITS; RETINA; VITREOUS BODY;

EID: 21744435077     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.03.010     Document Type: Article

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