Dissociation of inflammatory mediators and function: Experimental lung injury in nonpulmonary sepsis

Critical Care Medicine

Volumn 41, Issue 1, 2013, Pages 151-158

  Uematsu, Satoko ^a   Engelberts, Doreen ^a   Peltekova, Vanya ^a   Otulakowski, Gail ^a   Post, Martin ^a   Kavanagh, Brian P ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

lung injury; mechanical ventilation; mediators; sepsis

Indexed keywords

CHEMOKINE; DEXAMETHASONE; INTERLEUKIN 6; KERATINOCYTE STIMULATING FACTOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CECAL LIGATION AND PERFORATION; CECUM DISEASE; DRUG MECHANISM; LUNG ALVEOLUS PROTEINOSIS; LUNG FUNCTION; LUNG INJURY; LUNG LAVAGE; MALE; MOUSE; NONHUMAN; OXYGENATION; PNEUMONIA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEPSIS; TIDAL VOLUME;

ANIMALS; BIOLOGICAL MARKERS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOKINES; INFLAMMATION MEDIATORS; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; RANDOM ALLOCATION; RESPIRATION, ARTIFICIAL; SEPSIS; TIDAL VOLUME; TUMOR NECROSIS FACTOR-ALPHA; VENTILATOR-INDUCED LUNG INJURY;

EID: 84872054757     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e318267606f     Document Type: Article

References (33)

1. Villar J, Blanco J, Añón JM, et al; ALIEN Network: The ALIEN study: Incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intensive Care Med 2011; 37:1932-1941
2. Puneet P, Moochhala S, Bhatia M: Chemokines in acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 2005; 288: L3-15
3. Jaecklin T, Otulakowski G, Kavanagh BP: Do soluble mediators cause ventilator-induced lung injury and multi-organ failure? Intensive Care Med 2010; 36:750-757
4. Plötz FB, Slutsky AS, van Vught AJ, et al: Ventilator-induced lung injury and multiple system organ failure: A critical review of facts and hypotheses. Intensive Care Med 2004; 30:1865-1872
5. Altemeier WA, Matute-Bello G, Frevert CW, et al: Mechanical ventilation with moderate tidal volumes synergistically increases lung cytokine response to systemic endotoxin. Am J Physiol Lung Cell Mol Physiol 2004; 287:L533-L542
6. O'Dea KP, Wilson MR, Dokpesi JO, et al: Mobilization and margination of bone marrow Gr-1high monocytes during subclinical endotoxemia predisposes the lungs toward acute injury. J Immunol 2009; 182:1155-1166
7. UematsuS, Engelberts S, Peltekova S, et al: Effects of dexamethasone on priming of acute lung injury [abstract, ATS International Conference, Toronto]. Am J Respir Crit Care Med 2008; 177:177-178
8. Abcejo A, Andrejko KM, Ochroch EA, et al: Impaired hepatocellular regeneration in murine sepsis is dependent on regulatory protein levels. Shock 2011; 36:471-477
9. Ngiam N, Peltekova V, Engelberts D, et al: Early growth response-1 worsens ventilator-induced lung injury by up-regulating prostanoid synthesis. Am J Respir Crit Care Med 2010; 181:947-956
10. Peltekova V, Engelberts D, Otulakowski G, et al: Hypercapnic acidosis in ventilator-induced lung injury. Intensive Care Med 2010; 36:869-878
11. Brégeon F, Delpierre S, Chetaille B, et al: Mechanical ventilation affects lung function and cytokine production in an experimental model of endotoxemia. Anesthesiology 2005; 102:331-339
12. Schreiber T, Hueter L, Schwarzkopf K, et al: Increased susceptibility to ventilator-associated lung injury persists after clinical recovery from experimental endotoxemia. Anesthesiology 2006; 104: 133-141
13. Kawano T, Mori S, Cybulsky M, et al: Effect of granulocyte depletion in a ventilated surfactant-depleted lung. J Appl Physiol 1987; 62:27-33
14. Bhatia M, Zemans RL, Jeyaseelan S: Role of chemokines in the pathogenesis of acute lung injury. Am J Respir Cell Mol Biol 2012; 46:566-572
15. Copland IB, Reynaud D, Pace-Asciak C, et al: Mechanotransduction of stretch-induced prostanoid release by fetal lung epithelial cells. Am J Physiol Lung Cell Mol Physiol 2006; 291:L487-L495
16. Kuipers MT, van der Poll T, Schultz MJ, et al: Bench-to-bedside review: Damage-associated molecular patterns in the onset of ventilator-induced lung injury. Crit Care 2011; 15:235
17. Vlahakis NE, Hubmayr RD: Cellular stress failure in ventilator-injured lungs. Am J Respir Crit Care Med 2005; 171:1328-1342
18. Dreyfuss D, Saumon G: Ventilator-induced lung injury: Lessons from experimental studies. Am J Respir Crit Care Med 1998; 157: 294-323
19. Pierrakos C, Vincent JL: The changing pattern of ARDS over time: A comparison of two periods. Eur Respir J 2012; 40:589-595
20. Alcón A, Fàbregas N, Torres A: Pathophysiology of pneumonia. Clin Chest Med 2005; 26:39-46
21. Rentsendorj O, Damarla M, Aggarwal NR, et al: Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury. Am J Physiol Lung Cell Mol Physiol 2011; 301:L161-L170
22. Silva PL, Cruz FF, Fujisaki LC, et al: Hypervolemia induces and potentiates lung damage after recruitment maneuver in a model of sepsis-induced acute lung injury. Crit Care 2010; 14:R114
23. Hu G, Malik AB, Minshall RD: Toll-like receptor 4 mediates neutrophil sequestration and lung injury induced by endotoxin and hyperinflation. Crit Care Med 2010; 38:194-201
24. Silliman CC, Moore EE, Kelher MR, et al: Identification of lipids that accumulate during the routine storage of prestorage leukoreduced red blood cells and cause acute lung injury. Transfusion 2011; 51:2549-2554
25. Lee JS, Su X, Rackley C, et al: Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury. Anat Rec (Hoboken) 2011; 294:165-172
26. Lee L, Kelher MR, Moore EE, et al: Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase. J Surg Res 2012; 174:24-28
27. de Araújo CC, Silva JD, Samary CS, et al: Regular and moderate exercise before experimental sepsis reduces the risk of lung and distal organ injury. J Appl Physiol 2012; 112:1206-1214
28. Kim SD, Lee HY, Shim JW, et al: Activation of CXCR2 by extracellular matrix degradation product acetylated Pro-Gly-Pro has therapeutic effects against sepsis. Am J Respir Crit Care Med 2011; 184:243-251
29. Imai Y, Parodo J, Kajikawa O, et al: Injurious mechanical ventilation and end-organ epithelial cell apoptosis and organ dysfunction in an experimental model of acute respiratory distress syndrome. JAMA 2003; 289:2104-2112
30. Marik PE, Meduri GU, Rocco PR, et al: Glucocorticoid treatment in acute lung injury and acute respiratory distress syndrome. Crit Care Clin 2011; 27:589-607
31. Nin N, Lorente JA, Fernández-Segoviano P, et al: High-tidal volume ventilation aggravates sepsis-induced multiorgan dysfunction in a dexamethasone-inhibitable manner. Shock 2009; 31:429-434
32. Copland IB, Kavanagh BP, Engelberts D, et al: Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med 2003; 168:1051-1059
33. O'Mahony DS, Liles WC, Altemeier WA, et al: Mechanical ventilation interacts with endotoxemia to induce extrapulmonary organ dysfunction. Crit Care 2006; 10:R136