High-tidal volume ventilation aggravates sepsis-induced multiorgan dysfunction in a dexamethasone-inhibitable manner

Shock

Volumn 31, Issue 4, 2009, Pages 429-434

  Nin, Nicolás ^a,b   Lorente, José A ^a   Fernández Segoviano, Pilar ^a   De Paula, Maria ^a   Ferruelo, Antonio ^a,c   Esteban, Andrés ^a  

^a HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Dexamethasone; Mechanical ventilation; Multiorgan dysfunction; Sepsis; Ventilator induced lung injury

Indexed keywords

CYCLOOXYGENASE 2; DEXAMETHASONE; INDUCIBLE NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY CATHETER; ARTICLE; ARTIFICIAL VENTILATION; BLOOD CHEMISTRY; BLOOD FLOW; CECUM; CONTROL GROUP; CONTROLLED STUDY; GAS EXCHANGE; HEART; HEMODYNAMICS; HISTOPATHOLOGY; HYPERLACTATEMIA; HYPOTENSION; INFLAMMATION; LIGATION; LIVER; LIVER INJURY; LUNG INJURY; LUNG MECHANICS; LUNG VENTILATION; MALE; METABOLIC ACIDOSIS; MULTIPLE ORGAN FAILURE; NONHUMAN; POSITIVE END EXPIRATORY PRESSURE; PUNCTURE; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPSIS; THORACIC AORTA; TIDAL VOLUME; UPREGULATION; VENTILATED PATIENT;

ANIMALS; CECUM; CYCLOOXYGENASE 2; DEXAMETHASONE; GENE EXPRESSION; MALE; MULTIPLE ORGAN FAILURE; NITRIC OXIDE SYNTHASE TYPE II; POSITIVE-PRESSURE RESPIRATION; RATS; RATS, SPRAGUE-DAWLEY; RNA; SEPSIS;

EID: 64849116789     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e318188b720     Document Type: Article

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