Cell intrinsic and extrinsic factors contribute to enhance neural circuit reconstruction following transplantation in Parkinsonian mice

Journal of Physiology

Volumn 591, Issue 1, 2013, Pages 77-91

  Kauhausen, Jessica ^a   Thompson, Lachlan H ^a   Parish, Clare L ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL TRANSPLANTATION; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; EMBRYO; FEMALE; FUNCTIONAL ASSESSMENT; GRAFT SURVIVAL; INNERVATION; MOTOR PERFORMANCE; MOUSE; NERVE FIBER GROWTH; NONHUMAN; PARKINSONISM; PHENOTYPE; PRIORITY JOURNAL; TISSUE GRAFT;

ANIMALS; CELL TRANSPLANTATION; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FEMALE; FETAL TISSUE TRANSPLANTATION; MICE; NEURAL PATHWAYS; PARKINSON DISEASE; SUBSTANTIA NIGRA;

EID: 84872017426     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2012.243063     Document Type: Article

References (48)

1. Bayer SA, Wills KV, Triarhou LC & Ghetti B (1995). Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse. Exp Brain Res 105, 191-199.
2. Bentlage C, Nikkhah G, Cunningham MG & Bjorklund A (1999). Reformation of the nigrostriatal pathway by fetal dopaminergic micrografts into the substantia nigra is critically dependent on the age of the host. Exp Neurol 159, 177-190.
3. Bjorklund A & Dunnett SB (2007). Dopamine neuron systems in the brain: an update. Trends Neurosci 30, 194-202.
4. Bjorklund A, Rosenblad C, Winkler C & Kirik D (1997). Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiol Dis 4, 186-200.
5. Bjorklund A, Stenevi U, Schmidt RH, Dunnett SB & Gage FH (1983). Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites. Acta Physiol Scand Suppl 522, 9-18.
6. Blaess S, Bodea GO, Kabanova A, Chanet S, Mugniery E, Derouiche A, Stephen D & Joyner AL (2011). Temporal-spatial changes in Sonic Hedgehog expression and signalling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Dev 6, 29.
7. Blakely BD, Bye CR, Fernando CV, Horne MK, Macheda ML, Stacker SA, Arenas E & Parish CL (2011). Wnt5a regulates midbrain dopaminergic axon growth and guidance. PLoS One 6, e18373.
8. Brundin P, Barker RA & Parmar M (2010). Neural grafting in Parkinson's disease: problems and possibilities. Prog Brain Res 184, 265-294.
9. Brundin P, Isacson O & Bjorklund A (1985). Monitoring of cell viability in suspensions of embryonic CNS tissue and its use as a criterion for intracerebral graft survival. Brain Res 331, 251-259.
10. Bye CR, Thompson LH & Parish CL (2012). Birth dating of midbrain dopamine neurons identifies A9 enriched tissue for transplantation into Parkinsonian mice. Exp Neurol 236, 58-68.
11. Dahlström A & Fuxe K (1964). Evidence for existence of monoamine-containing neurons in central nervous system. I. Demonstration of monoamines in cell bodies of brain stem neurons. Acta Physiol Scand 62, 5-55.
12. Denham M, Parish CL, Leaw B, Wright J, Reid CA, Petrou S, Dottori M & Thompson LH (2012). Neurons derived from human embryonic stem cells extend long-distance axonal projections through growth along host white matter tracts after cerebral transplantation. Front Cell Neurosci 6, 11.
13. Dunnett SB & Bjorklund A (1997). Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain. Brain Res Brain Res Protoc 1, 91-99.
14. Dunnett SB, Bjorklund A, Schmidt RH, Stenevi U & Iversen SD (1983). Intracerebral grafting of neuronal cell suspensions. IV. Behavioural recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites. Acta Physiol Scand Suppl 522, 29-37.
15. Eslamboli A, Georgievska B, Ridley RM, Baker HF, Muzyczka N, Burger C, Mandel RJ, Annett L, Kirik D (2005). Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease. J Neurosci. 25, 769-777.
16. Franklin KBJ & Paxinos G (1997). The Mouse Brain in Stereotaxic Coordinates. Academic Press, San Diego.
17. Freeman TB, Sanberg PR, Nauert GM, Boss BD, Spector D, Olanow CW & Kordower JH (1995). The influence of donor age on the survival of solid and suspension intraparenchymal human embryonic nigral grafts. Cell Transplant 4, 141-154.
18. Gaillard A, Decressac M, Frappe I, Fernagut PO, Prestoz L, Besnard S & Jaber M (2009). Anatomical and functional reconstruction of the nigrostriatal pathway by intranigral transplants. Neurobiol Dis 35, 477-488.
19. Gates MA, Torres EM, White A, Fricker-Gates RA & Dunnett SB (2006). Re-examining the ontogeny of substantia nigra dopamine neurons. Eur J Neurosci 23, 1384-1390.
20. Grealish S, Jonsson ME, Li M, Kirik D, Bjorklund A & Thompson LH (2010). The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson's disease. Brain 133, 482-495.
21. Hahn M, Timmer M & Nikkhah G (2009). Survival and early functional integration of dopaminergic progenitor cells following transplantation in a rat model of Parkinson's disease. J Neurosci Res 87, 2006-2019.
22. Hammond R, Blaess S & Abeliovich A (2009). Sonic hedgehog is a chemoattractant for midbrain dopaminergic axons. PLoS One 4, e7007.
23. Hayes L, Zhang Z, Albert P, Zervas M & Ahn S (2011). Timing of Sonic hedgehog and Gli1 expression segregates midbrain dopamine neurons. J Comp Neurol 519, 3001-3018.
24. Joksimovic M, Anderegg A, Roy A, Campochiaro L, Yun B, Kittappa R, McKay R & Awatramani R (2009). Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools. Proc Natl Acad Sci U S A 106, 19185-19190.
25. Koprivica V, Cho KS, Park JB, Yiu G, Atwal J, Gore B, Kim JA, Lin E, Tessier-Lavigne M, Chen DF & He Z (2005). EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans. Science 310, 106-110.
26. Kuan WL, Lin R, Tyers P & Barker RA (2007). The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias. Neurobiol Dis 25, 594-608.
27. Mendez I, Sanchez-Pernaute R, Cooper O, Vinuela A, Ferrari D, Bjorklund L, Dagher A & Isacson O (2005). Cell type analysis of functional fetal dopamine cell suspension transplants in the striatum and substantia nigra of patients with Parkinson's disease. Brain 128, 1498-1510.
28. Nikkhah G, Bentlage C, Cunningham MG & Bjorklund A (1994a). Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. J Neurosci 14, 3449-3461.
29. Nikkhah G, Cunningham MG, Jodicke A, Knappe U & Bjorklund A (1994b). Improved graft survival and striatal reinnervation by microtransplantation of fetal nigral cell suspensions in the rat Parkinson model. Brain Res 633, 133-143.
30. O'Keeffe FE, Scott SA, Tyers P, O'Keeffe GW, Dalley JW, Zufferey R & Caldwell MA (2008). Induction of A9 dopaminergic neurons from neural stem cells improves motor function in an animal model of Parkinson's disease. Brain 131, 630-641.
31. Parish CL, Finkelstein DI, Drago J, Borrelli E & Horne MK (2001). The role of dopamine receptors in regulating the size of axonal arbors. J Neurosci 21, 5147-5157.
32. Parish CL & Thompson LH (2012). Neural progenitor cell transplantation in Parkinson's disease models. In Neural Progenitor Cells: Methods and Protocols, ed. Reynolds LDaB. Humana Press, Totowa, NJ.
33. Rangasamy SB, Soderstrom K, Bakay RA & Kordower JH (2010). Neurotrophic factor therapy for Parkinson's disease. Prog Brain Res 184, 237-264.
34. Redmond DE Jr, Elsworth JD, Roth RH, Leranth C, Collier TJ, Blanchard B, Bjugstad KB, Samulski RJ, Aebischer P & Sladek JR Jr (2009). Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF. J Comp Neurol 515, 31-40.
35. Rosenblad C, Martinez-Serrano A & Bjorklund A (1996). Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. Neuroscience 75, 979-985.
36. Roussa E, Farkas LM & Krieglstein K (2004). TGF-β promotes survival on mesencephalic dopaminergic neurons in cooperation with Shh and FGF-8. Neurobiol Dis 16, 300-310.
37. Sauer H, Frodl EM, Kupsch A, ten Bruggencate G & Oertel WH (1992). Cryopreservation, survival and function of intrastriatal fetal mesencephalic grafts in a rat model of Parkinson's disease. Exp Brain Res 90, 54-62.
38. Sawamoto K, Nakao N, Kobayashi K, Matsushita N, Takahashi H, Kakishita K, Yamamoto A, Yoshizaki T, Terashima T, Murakami F, Itakura T & Okano H (2001). Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons. Proc Natl Acad Sci U S A 98, 6423-6428.
39. Shen Y, Tenney AP, Busch SA, Horn KP, Cuascut FX, Liu K, He Z, Silver J & Flanagan JG (2009). PTPσ is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science 326, 592-596.
40. Sinclair SR, Fawcett JW & Dunnett SB (1999). Dopamine cells in nigral grafts differentiate prior to implantation. Eur J Neurosci 11, 4341-4348.
41. Smith GA, Heuer A, Dunnett SB & Lane EL (2012). Unilateral nigrostriatal 6-hydroxydopamine lesions in mice II: predicting l-DOPA-induced dyskinesia. Behav Brain Res 226, 281-292.
42. Thompson L, Barraud P, Andersson E, Kirik D & Bjorklund A (2005). Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and efferent projections. J Neurosci 25, 6467-6477.
43. Thompson LH, Grealish S, Kirik D & Bjorklund A (2009). Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain. Eur J Neurosci 30, 625-638.
44. Torres EM, Monville C, Gates MA, Bagga V & Dunnett SB (2007). Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease. Neuroscience 146, 1606-1617.
45. Torres EM, Monville C, Lowenstein PR, Castro MG & Dunnett SB (2005). Delivery of sonic hedgehog or glial derived neurotrophic factor to dopamine-rich grafts in a rat model of Parkinson's disease using adenoviral vectors: Increased yield of dopamine cells is dependent on embryonic donor age. Brain Res Bull 68, 31-41.
46. Van Den Heuvel DM & Pasterkamp RJ (2008). Getting connected in the dopamine system. Prog Neurobiol 85, 75-93.
47. Winkler C, Kirik D & Bjorklund A (2005). Cell transplantation in Parkinson's disease: how can we make it work Trends Neurosci 28, 86-92.
48. Yurek DM (1997). Intranigral transplants of fetal ventral mesencephalic tissue attenuate D1-agonist-induced rotational behavior. Exp Neurol 143, 1-9.