Proteasome inhibition attenuates heart failure during the late stages of pressure overload through alterations in collagen expression

Biochemical Pharmacology

Volumn 85, Issue 2, 2013, Pages 223-233

  Ma, Yuedong ^a   Chen, Yili ^a   Yang, Yang ^b   Chen, Baolin ^c   Liu, Dan ^a   Xiong, Zhaojun ^b   Zhang, Chengxi ^b   Dong, Yugang ^a,d  

^a THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c GUIZHOU PROVINCIAL PEOPLE'S HOSPITAL   (China)

^d BEIJING HOSPITAL   (China)

Author keywords

Collagen expression; Heart failure; Late stage of pressure overload; NF B; Proteasome inhibitor

Indexed keywords

ANGIOTENSIN II; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; COLLAGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEASOME; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CLINICAL EVALUATION; COLLAGEN SYNTHESIS; COMORBIDITY; CONTROLLED STUDY; ENZYME INHIBITION; FIBROBLAST; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SHAM PROCEDURE; SIGNAL TRANSDUCTION; TREATMENT DURATION; UBIQUITINATION;

ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; COLLAGEN; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FIBROSIS; HEART FAILURE; HEART VENTRICLES; HYPERTENSION; LEUPEPTINS; MALE; PROTEASOME INHIBITORS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SEVERITY OF ILLNESS INDEX; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84872010741     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.10.025     Document Type: Article

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