MG132 treatment attenuates cardiac remodeling and dysfunction following aortic banding in rats via the NF-κB/TGFβ1 pathway

Biochemical Pharmacology

Volumn 81, Issue 10, 2011, Pages 1228-1236

  Ma, Yuedong ^a   Chen, Baolin ^b   Liu, Dan ^a   Yang, Yang ^a   Xiong, Zhaojun ^a   Zeng, Junyi ^a   Dong, Yugang ^a,c  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUIZHOU PROVINCIAL PEOPLE'S HOSPITAL   (China)

^c BEIJING HOSPITAL   (China)

Author keywords

Cardiac remodeling; Heart failure; NF B; Pressure overload; Proteasome inhibition

Indexed keywords

ANGIOTENSIN II; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; COLLAGEN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEASOME; SMAD2 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN;

ABDOMINAL AORTA; ANGIOTENSIN BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; BODY WEIGHT; CARDIAC REMODELING; CONTROLLED STUDY; DOPPLER ECHOCARDIOGRAPHY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; HEART DISEASE; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE; HEART MUSCLE FIBROSIS; HEART VENTRICLE SEPTUM; HYPERTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; ANIMALS; AORTA, ABDOMINAL; COLLAGEN; CONSTRICTION; FIBROSIS; HEMODYNAMICS; HYPERTENSION; LEUPEPTINS; MALE; MYOCARDIUM; NF-KAPPA B; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; UBIQUITIN; VENTRICULAR REMODELING;

EID: 79955464405     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2011.03.009     Document Type: Article

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