Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: Intermolecular bivalent binding

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1834, Issue 2, 2013, Pages 524-535

  De Mol, Nico J ^a   Kruijtzer, John A W ^a   Moret, Ed E ^a   Broutin, Isabelle ^b   Liskamp, Rob M J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Divalent binding; Grb2; Polyproline; SH3 domain; Sos protein; Surface plasmon resonance (SPR)

Indexed keywords

DIVALENT CATION; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; POLYPROLINE; PROTEIN SH3; SOS PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; KINETICS; LIGAND BINDING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN IMMOBILIZATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SENSOR; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GRB2 ADAPTOR PROTEIN; HUMANS; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 84872005064     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2012.11.001     Document Type: Article

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