메뉴 건너뛰기




Volumn 87, Issue 2, 2013, Pages 935-950

Viral genome methylation differentially affects the ability of BZLF1 versus BRLF1 to activate Epstein-Barr virus lytic gene expression and viral replication

Author keywords

[No Author keywords available]

Indexed keywords

IMMEDIATE EARLY PROTEIN BRLF1; IMMEDIATE EARLY PROTEIN BZLF1; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

EID: 84871986829     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01790-12     Document Type: Article
Times cited : (55)

References (67)
  • 2
    • 84871957374 scopus 로고    scopus 로고
    • In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott Williams&Wilkins, Philadelphia, PA.
    • Kieff E, Rickinson AB. 2007. Epstein-Barr virus and Its Replication, p 1225-2654. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott Williams&Wilkins, Philadelphia, PA.
    • (2007) Epstein-Barr virus and Its Replication , pp. 1225-2654
    • Kieff, E.1    Rickinson, A.B.2
  • 3
    • 34249064632 scopus 로고    scopus 로고
    • In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott Williams&Wilkins, Philadelphia, PA.
    • Rickinson AB, Kieff E. 2007. Epsetin-Barr virus, p 2655-2700. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott Williams&Wilkins, Philadelphia, PA.
    • (2007) Epsetin-Barr virus , pp. 2655-2700
    • Rickinson, A.B.1    Kieff, E.2
  • 6
    • 0026004036 scopus 로고
    • Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cells
    • Yates JL, Guan N. 1991. Epstein-Barr virus-derived plasmids replicate only once per cell cycle and are not amplified after entry into cells. J. Virol. 65:483-488.
    • (1991) J. Virol. , vol.65 , pp. 483-488
    • Yates, J.L.1    Guan, N.2
  • 8
    • 0026316328 scopus 로고
    • Epstein-Barr virus infection in oral hairy leukoplakia: virus replication in the absence of a detectable latent phase
    • Niedobitek G, Young LS, Lau R, Brooks L, Greenspan D, Greenspan JS, Rickinson AB. 1991. Epstein-Barr virus infection in oral hairy leukoplakia: virus replication in the absence of a detectable latent phase. J. Gen. Virol. 72:3035-3046.
    • (1991) J. Gen. Virol. , vol.72 , pp. 3035-3046
    • Niedobitek, G.1    Young, L.S.2    Lau, R.3    Brooks, L.4    Greenspan, D.5    Greenspan, J.S.6    Rickinson, A.B.7
  • 9
    • 84855980581 scopus 로고    scopus 로고
    • The lytic phase of Epstein- Barr virus requires a viral genome with 5-methylcytosine residues in CpG sites
    • Kalla M, Göbel C, Hammerschmidt W. 2012. The lytic phase of Epstein- Barr virus requires a viral genome with 5-methylcytosine residues in CpG sites. J. Virol. 86:447-458.
    • (2012) J. Virol. , vol.86 , pp. 447-458
    • Kalla, M.1    Göbel, C.2    Hammerschmidt, W.3
  • 11
    • 76249132533 scopus 로고    scopus 로고
    • AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome
    • Kalla M, Schmeinck A, Bergbauer M, Pich D, Hammerschmidt W. 2010. AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc. Natl. Acad. Sci. U. S. A. 107:850-855.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 850-855
    • Kalla, M.1    Schmeinck, A.2    Bergbauer, M.3    Pich, D.4    Hammerschmidt, W.5
  • 12
    • 80052476882 scopus 로고    scopus 로고
    • Epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal center B cells and their relevance to the pathogenesis of Hodgkin's lymphoma
    • Leonard S, Wei W, Anderton J, Vockerodt M, Rowe M, Murray PG, Woodman CB. 2011. Epigenetic and transcriptional changes which follow Epstein-Barr virus infection of germinal center B cells and their relevance to the pathogenesis of Hodgkin's lymphoma. J. Virol. 85:9568-9577.
    • (2011) J. Virol. , vol.85 , pp. 9568-9577
    • Leonard, S.1    Wei, W.2    Anderton, J.3    Vockerodt, M.4    Rowe, M.5    Murray, P.G.6    Woodman, C.B.7
  • 13
    • 0025290086 scopus 로고
    • The Epstein- Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif
    • Chang YN, Dong DL, Hayward GS, Hayward SD. 1990. The Epstein- Barr virus Zta transactivator: a member of the bZIP family with unique DNA-binding specificity and a dimerization domain that lacks the characteristic heptad leucine zipper motif. J. Virol. 64:3358-3369.
    • (1990) J. Virol. , vol.64 , pp. 3358-3369
    • Chang, Y.N.1    Dong, D.L.2    Hayward, G.S.3    Hayward, S.D.4
  • 14
    • 0023503201 scopus 로고
    • Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency
    • Countryman J, Jenson H, Seibl R, Wolf H, Miller G. 1987. Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency. J. Virol. 61:3672-3679.
    • (1987) J. Virol. , vol.61 , pp. 3672-3679
    • Countryman, J.1    Jenson, H.2    Seibl, R.3    Wolf, H.4    Miller, G.5
  • 15
    • 0025177308 scopus 로고
    • An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators
    • Cox MA, Leahy J, Hardwick JM. 1990. An enhancer within the divergent promoter of Epstein-Barr virus responds synergistically to the R and Z transactivators. J. Virol. 64:313-321.
    • (1990) J. Virol. , vol.64 , pp. 313-321
    • Cox, M.A.1    Leahy, J.2    Hardwick, J.M.3
  • 16
    • 0034660443 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators
    • Feederle R, Kost M, Baumann M, Janz A, Drouet E, Hammerschmidt W, Delecluse HJ. 2000. The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators. EMBO J. 19:3080-3089.
    • (2000) EMBO J. , vol.19 , pp. 3080-3089
    • Feederle, R.1    Kost, M.2    Baumann, M.3    Janz, A.4    Drouet, E.5    Hammerschmidt, W.6    Delecluse, H.J.7
  • 17
    • 0023889721 scopus 로고
    • A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen
    • Hardwick JM, Lieberman PM, Hayward SD. 1988. A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen. J. Virol. 62:2274-2284.
    • (1988) J. Virol. , vol.62 , pp. 2274-2284
    • Hardwick, J.M.1    Lieberman, P.M.2    Hayward, S.D.3
  • 18
    • 0024550905 scopus 로고
    • The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters
    • Kenney S, Kamine J, Holley-Guthrie E, Lin JC, Mar EC, Pagano J. 1989. The Epstein-Barr virus (EBV) BZLF1 immediate-early gene product differentially affects latent versus productive EBV promoters. J. Virol. 63: 1729-1736.
    • (1989) J. Virol. , vol.63 , pp. 1729-1736
    • Kenney, S.1    Kamine, J.2    Holley-guthrie, E.3    Lin, J.C.4    Mar, E.C.5    Pagano, J.6
  • 19
    • 0024379416 scopus 로고
    • The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle
    • Rooney CM, Rowe DT, Ragot T, Farrell PJ. 1989. The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle. J. Virol. 63:3109-3116.
    • (1989) J. Virol. , vol.63 , pp. 3109-3116
    • Rooney, C.M.1    Rowe, D.T.2    Ragot, T.3    Farrell, P.J.4
  • 20
    • 0029830047 scopus 로고    scopus 로고
    • Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism
    • Zalani S, Holley-Guthrie E, Kenney S. 1996. Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism. Proc. Natl. Acad. Sci. U. S. A. 93:9194-9199.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 9194-9199
    • Zalani, S.1    Holley-guthrie, E.2    Kenney, S.3
  • 21
    • 0024469056 scopus 로고
    • Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos
    • Farrell PJ, Rowe DT, Rooney CM, Kouzarides T. 1989. Epstein-Barr virus BZLF1 trans-activator specifically binds to a consensus AP-1 site and is related to c-fos. EMBO J. 8:127-132.
    • (1989) EMBO J. , vol.8 , pp. 127-132
    • Farrell, P.J.1    Rowe, D.T.2    Rooney, C.M.3    Kouzarides, T.4
  • 22
    • 0025214570 scopus 로고
    • Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1
    • Flemington E, Speck SH. 1990. Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1. J. Virol. 64:1227-1232.
    • (1990) J. Virol. , vol.64 , pp. 1227-1232
    • Flemington, E.1    Speck, S.H.2
  • 23
    • 0025604607 scopus 로고
    • Evidence for coiled-coil dimer formation by an Epstein-Barr virus transactivator that lacks a heptad repeat of leucine residues
    • Flemington E, Speck SH. 1990. Evidence for coiled-coil dimer formation by an Epstein-Barr virus transactivator that lacks a heptad repeat of leucine residues. Proc. Natl. Acad. Sci. U. S. A. 87:9459-9463.
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 9459-9463
    • Flemington, E.1    Speck, S.H.2
  • 24
    • 80053966424 scopus 로고    scopus 로고
    • Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor
    • doi:10.1371/journal.pone.0025922
    • Flower K, Thomas D, Heather J, Ramasubramanyan S, Jones S, Sinclair AJ. 2011. Epigenetic control of viral life-cycle by a DNA-methylation dependent transcription factor. PLoS One 6:e25922. doi:10.1371/ journal.pone.0025922.
    • (2011) PLoS One , vol.6
    • Flower, K.1    Thomas, D.2    Heather, J.3    Ramasubramanyan, S.4    Jones, S.5    Sinclair, A.J.6
  • 25
    • 0025255970 scopus 로고
    • The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions
    • Lieberman PM, Hardwick JM, Sample J, Hayward GS, Hayward SD. 1990. The zta transactivator involved in induction of lytic cycle gene expression in Epstein-Barr virus-infected lymphocytes binds to both AP-1 and ZRE sites in target promoter and enhancer regions. J. Virol. 64:1143-1155.
    • (1990) J. Virol. , vol.64 , pp. 1143-1155
    • Lieberman, P.M.1    Hardwick, J.M.2    Sample, J.3    Hayward, G.S.4    Hayward, S.D.5
  • 26
    • 0038678667 scopus 로고    scopus 로고
    • Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta
    • Liu P, Speck SH. 2003. Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta. Virology 310: 199-206.
    • (2003) Virology , vol.310 , pp. 199-206
    • Liu, P.1    Speck, S.H.2
  • 27
    • 6944244957 scopus 로고    scopus 로고
    • The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome
    • Bhende PM, Seaman WT, Delecluse H-J, Kenney SC. 2004. The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome. Nat. Genet. 36:1099-1104.
    • (2004) Nat. Genet. , vol.36 , pp. 1099-1104
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.-J.3    Kenney, S.C.4
  • 28
    • 19944397140 scopus 로고    scopus 로고
    • BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186
    • Bhende PM, Seaman WT, Delecluse H-J, Kenney SC. 2005. BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. J. Virol. 79:7338-7348.
    • (2005) J. Virol. , vol.79 , pp. 7338-7348
    • Bhende, P.M.1    Seaman, W.T.2    Delecluse, H.-J.3    Kenney, S.C.4
  • 29
    • 63449134294 scopus 로고    scopus 로고
    • Methylation-dependent binding of the Epstein-Barr virus BZLF1 protein to viral promoters
    • doi:10.1371/journal.ppat.1000356.
    • Dickerson SJ, Xing Y, Robinson AR, Seaman WT, Gruffat H, Kenney SC. 2009. Methylation-dependent binding of the Epstein-Barr virus BZLF1 protein to viral promoters. PLoS Pathog. 5:e1000356. doi:10.1371/ journal.ppat.1000356.
    • (2009) PLoS Pathog. , vol.5
    • Dickerson, S.J.1    Xing, Y.2    Robinson, A.R.3    Seaman, W.T.4    Gruffat, H.5    Kenney, S.C.6
  • 30
    • 0032506210 scopus 로고    scopus 로고
    • Rescue of the Epstein-Barr virus BZLF1 mutant, Z(S186A), early gene activation defect by the BRLF1 gene product
    • Adamson AL, Kenney SC. 1998. Rescue of the Epstein-Barr virus BZLF1 mutant, Z(S186A), early gene activation defect by the BRLF1 gene product. Virology 251:187-197.
    • (1998) Virology , vol.251 , pp. 187-197
    • Adamson, A.L.1    Kenney, S.C.2
  • 31
    • 0033029629 scopus 로고    scopus 로고
    • Amino acid substitutions reveal distinct functions of serine 186 of the ZEBRA protein in activation of early lytic cycle genes and synergy with the Epstein-Barr virus R transactivator
    • Francis A, Ragoczy T, Gradoville L, Heston L, El-Guindy A, Endo Y, Miller G. 1999. Amino acid substitutions reveal distinct functions of serine 186 of the ZEBRA protein in activation of early lytic cycle genes and synergy with the Epstein-Barr virus R transactivator. J. Virol. 73:4543-4551.
    • (1999) J. Virol. , vol.73 , pp. 4543-4551
    • Francis, A.1    Ragoczy, T.2    Gradoville, L.3    Heston, L.4    El-guindy, A.5    Endo, Y.6    Miller, G.7
  • 32
    • 0031694397 scopus 로고    scopus 로고
    • The Epstein-Barr virus Rta protein activates lytic cycle genes and can disrupt latency in B lymphocytes
    • Ragoczy T, Heston L, Miller G. 1998. The Epstein-Barr virus Rta protein activates lytic cycle genes and can disrupt latency in B lymphocytes. J. Virol. 72:7978-7984.
    • (1998) J. Virol. , vol.72 , pp. 7978-7984
    • Ragoczy, T.1    Heston, L.2    Miller, G.3
  • 33
    • 22544459366 scopus 로고    scopus 로고
    • Marked variation in response of consensus binding elements for the Rta protein of Epstein- Barr virus
    • Chen L-W, Chang P-J, Delecluse H-J, Miller G. 2005. Marked variation in response of consensus binding elements for the Rta protein of Epstein- Barr virus. J. Virol. 79:9635-9650.
    • (2005) J. Virol. , vol.79 , pp. 9635-9650
    • Chen, L.-W.1    Chang, P.-J.2    Delecluse, H.-J.3    Miller, G.4
  • 34
    • 0026541305 scopus 로고
    • Characterization of an R-binding site mediating the R-induced activation of the Epstein-Barr virus BMLF1 promoter
    • Gruffat H, Duran N, Buisson M, Wild F, Buckland R, Sergeant A. 1992. Characterization of an R-binding site mediating the R-induced activation of the Epstein-Barr virus BMLF1 promoter. J. Virol. 66:46-52.
    • (1992) J. Virol. , vol.66 , pp. 46-52
    • Gruffat, H.1    Duran, N.2    Buisson, M.3    Wild, F.4    Buckland, R.5    Sergeant, A.6
  • 35
    • 0025666546 scopus 로고
    • The enhancer factor R of Epstein-Barr virus (EBV) is a sequence-specific DNA binding protein
    • Gruffat H, Manet E, Rigolet A, Sergeant A. 1990. The enhancer factor R of Epstein-Barr virus (EBV) is a sequence-specific DNA binding protein. Nucleic Acids Res. 18:6835-6843.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 6835-6843
    • Gruffat, H.1    Manet, E.2    Rigolet, A.3    Sergeant, A.4
  • 36
    • 0028237964 scopus 로고
    • Characterization of the DNA-binding site repertoire for the Epstein-Barr virus transcription factor R
    • Gruffat H, Sergeant A. 1994. Characterization of the DNA-binding site repertoire for the Epstein-Barr virus transcription factor R. Nucleic Acids Res. 22:1172-1178.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1172-1178
    • Gruffat, H.1    Sergeant, A.2
  • 39
    • 0032708891 scopus 로고    scopus 로고
    • Role of the Epstein-Barr virus RTA protein in activation of distinct classes of viral lytic cycle genes
    • Ragoczy T, Miller G. 1999. Role of the Epstein-Barr virus RTA protein in activation of distinct classes of viral lytic cycle genes. J. Virol. 73:9858-9866.
    • (1999) J. Virol. , vol.73 , pp. 9858-9866
    • Ragoczy, T.1    Miller, G.2
  • 40
    • 77955794374 scopus 로고    scopus 로고
    • MCAF1 and synergistic activation of the transcription of Epstein-Barr virus lytic genes by Rta and Zta
    • Chang L-K, Chuang J-Y, Nakao M, Liu S-T. 2010. MCAF1 and synergistic activation of the transcription of Epstein-Barr virus lytic genes by Rta and Zta. Nucleic Acids Res. 38:4687-4700.
    • (2010) Nucleic Acids Res. , vol.38 , pp. 4687-4700
    • Chang, L.-K.1    Chuang, J.-Y.2    Nakao, M.3    Liu, S.-T.4
  • 41
    • 0034974152 scopus 로고    scopus 로고
    • Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation
    • Darr CD, Mauser A, Kenney S. 2001. Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation. J. Virol. 75: 6135-6142.
    • (2001) J. Virol. , vol.75 , pp. 6135-6142
    • Darr, C.D.1    Mauser, A.2    Kenney, S.3
  • 42
    • 0035026624 scopus 로고    scopus 로고
    • Autostimulation of the Epstein-Barr virus BRLF1 promoter is mediated through consensus Sp1 and Sp3 binding sites
    • Ragoczy T, Miller G. 2001. Autostimulation of the Epstein-Barr virus BRLF1 promoter is mediated through consensus Sp1 and Sp3 binding sites. J. Virol. 75:5240-5251.
    • (2001) J. Virol. , vol.75 , pp. 5240-5251
    • Ragoczy, T.1    Miller, G.2
  • 43
    • 80052286938 scopus 로고    scopus 로고
    • Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency
    • Robinson AR, Kwek SS, Hagemeier SR, Wille CK, Kenney SC. 2011. Cellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latency. J. Virol. 85:8940-8953.
    • (2011) J. Virol. , vol.85 , pp. 8940-8953
    • Robinson, A.R.1    Kwek, S.S.2    Hagemeier, S.R.3    Wille, C.K.4    Kenney, S.C.5
  • 44
    • 0023698910 scopus 로고
    • Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus
    • Hammerschmidt W, Sugden B. 1988. Identification and characterization of oriLyt, a lytic origin of DNA replication of Epstein-Barr virus. Cell 55:427-433.
    • (1988) Cell , vol.55 , pp. 427-433
    • Hammerschmidt, W.1    Sugden, B.2
  • 45
    • 0027282974 scopus 로고
    • A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus
    • Schepers A, Pich D, Hammerschmidt W. 1993. A transcription factor with homology to the AP-1 family links RNA transcription and DNA replication in the lytic cycle of Epstein-Barr virus. EMBO J. 12:3921-3929.
    • (1993) EMBO J. , vol.12 , pp. 3921-3929
    • Schepers, A.1    Pich, D.2    Hammerschmidt, W.3
  • 46
    • 0029944992 scopus 로고    scopus 로고
    • Activation of oriLyt, the lytic origin of DNA replication of Epstein-Barr virus, by BZLF1
    • Schepers A, Pich D, Hammerschmidt W. 1996. Activation of oriLyt, the lytic origin of DNA replication of Epstein-Barr virus, by BZLF1. Virology 220:367-376.
    • (1996) Virology , vol.220 , pp. 367-376
    • Schepers, A.1    Pich, D.2    Hammerschmidt, W.3
  • 47
    • 0029861946 scopus 로고    scopus 로고
    • A replication function associated with the activation domain of the Epstein-Barr virus Zta transactivator
    • Sarisky RT, Gao Z, Lieberman PM, Fixman ED, Hayward GS, Hayward SD. 1996. A replication function associated with the activation domain of the Epstein-Barr virus Zta transactivator. J. Virol. 70:8340-8347.
    • (1996) J. Virol. , vol.70 , pp. 8340-8347
    • Sarisky, R.T.1    Gao, Z.2    Lieberman, P.M.3    Fixman, E.D.4    Hayward, G.S.5    Hayward, S.D.6
  • 48
    • 0031710581 scopus 로고    scopus 로고
    • The Epstein-Barr virus lytic transactivator Zta interacts with the helicase-primase replication proteins
    • Gao Z, Krithivas A, Finan JE, Semmes OJ, Zhou S, Wang Y, Hayward SD. 1998. The Epstein-Barr virus lytic transactivator Zta interacts with the helicase-primase replication proteins. J. Virol. 72:8559-8567.
    • (1998) J. Virol. , vol.72 , pp. 8559-8567
    • Gao, Z.1    Krithivas, A.2    Finan, J.E.3    Semmes, O.J.4    Zhou, S.5    Wang, Y.6    Hayward, S.D.7
  • 49
    • 0029931715 scopus 로고    scopus 로고
    • Functional and physical interactions between the Epstein-Barr virus (EBV) proteins BZLF1 and BMRF1: effects on EBV transcription and lytic replication
    • Zhang Q, Hong Y, Dorsky D, Holley-Guthrie E, Zalani S, Elshiekh NA, Kiehl A, Le T, Kenney S. 1996. Functional and physical interactions between the Epstein-Barr virus (EBV) proteins BZLF1 and BMRF1: effects on EBV transcription and lytic replication. J. Virol. 70:5131-5142.
    • (1996) J. Virol. , vol.70 , pp. 5131-5142
    • Zhang, Q.1    Hong, Y.2    Dorsky, D.3    Holley-guthrie, E.4    Zalani, S.5    Elshiekh, N.A.6    Kiehl, A.7    Le, T.8    Kenney, S.9
  • 50
    • 79952431682 scopus 로고    scopus 로고
    • Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNADNA hybrid molecule at OriLyt
    • Rennekamp AJ, Lieberman PM. 2011. Initiation of Epstein-Barr virus lytic replication requires transcription and the formation of a stable RNADNA hybrid molecule at OriLyt. J. Virol. 85:2837-2850.
    • (2011) J. Virol. , vol.85 , pp. 2837-2850
    • Rennekamp, A.J.1    Lieberman, P.M.2
  • 51
    • 0037439799 scopus 로고    scopus 로고
    • Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability
    • Piboonniyom S, Duensing S, Swilling NW, Hasskarl J, Hinds PW, Münger K. 2003. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Res. 63: 476-483.
    • (2003) Cancer Res. , vol.63 , pp. 476-483
    • Piboonniyom, S.1    Duensing, S.2    Swilling, N.W.3    Hasskarl, J.4    Hinds, P.W.5    Münger, K.6
  • 52
    • 2942654609 scopus 로고    scopus 로고
    • Production of high-titer Epstein-Barr virus recombinants derived from Akata cells by using a bacterial artificial chromosome system
    • Kanda T, Yajima M, Ahsan N, Tanaka M, Takada K. 2004. Production of high-titer Epstein-Barr virus recombinants derived from Akata cells by using a bacterial artificial chromosome system. J. Virol. 78:7004-7015.
    • (2004) J. Virol. , vol.78 , pp. 7004-7015
    • Kanda, T.1    Yajima, M.2    Ahsan, N.3    Tanaka, M.4    Takada, K.5
  • 53
    • 38449102144 scopus 로고    scopus 로고
    • Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector
    • Klug M, Rehli M. 2006. Functional analysis of promoter CpG methylation using a CpG-free luciferase reporter vector. Epigenetics 1:127-130.
    • (2006) Epigenetics , vol.1 , pp. 127-130
    • Klug, M.1    Rehli, M.2
  • 56
    • 84857078927 scopus 로고    scopus 로고
    • Dynamic chromatin environment of key lytic cycle regulatory regions of the Epstein- Barr virus genome
    • Ramasubramanyan S, Osborn K, Flower K, Sinclair AJ. 2012. Dynamic chromatin environment of key lytic cycle regulatory regions of the Epstein- Barr virus genome. J. Virol. 86:1809-1819.
    • (2012) J. Virol. , vol.86 , pp. 1809-1819
    • Ramasubramanyan, S.1    Osborn, K.2    Flower, K.3    Sinclair, A.J.4
  • 57
    • 0028027740 scopus 로고
    • Optimal lengths for DNAs encapsidated by Epstein-Barr virus
    • Bloss TA, Sugden B. 1994. Optimal lengths for DNAs encapsidated by Epstein-Barr virus. J. Virol. 68:8217-8222.
    • (1994) J. Virol. , vol.68 , pp. 8217-8222
    • Bloss, T.A.1    Sugden, B.2
  • 59
    • 2342520167 scopus 로고    scopus 로고
    • The BRRF1 early gene of Epstein-Barr virus encodes a transcription factor that enhances induction of lytic infection by BRLF1
    • Hong GK, Delecluse H-J, Gruffat H, Morrison TE, Feng W-H, Sergeant A, Kenney SC. 2004. The BRRF1 early gene of Epstein-Barr virus encodes a transcription factor that enhances induction of lytic infection by BRLF1. J. Virol. 78:4983-4992.
    • (2004) J. Virol. , vol.78 , pp. 4983-4992
    • Hong, G.K.1    Delecluse, H.-J.2    Gruffat, H.3    Morrison, T.E.4    Feng, W-H.5    Sergeant, A.6    Kenney, S.C.7
  • 60
    • 0034979367 scopus 로고    scopus 로고
    • Epstein-Barr virus immediate-early protein BRLF1 interacts with CBP, promoting enhanced BRLF1 transactivation
    • Swenson JJ, Holley-Guthrie E, Kenney SC. 2001. Epstein-Barr virus immediate-early protein BRLF1 interacts with CBP, promoting enhanced BRLF1 transactivation. J. Virol. 75:6228-6234.
    • (2001) J. Virol. , vol.75 , pp. 6228-6234
    • Swenson, J.J.1    Holley-guthrie, E.2    Kenney, S.C.3
  • 61
    • 0032798394 scopus 로고    scopus 로고
    • The Epstein-Barr virus BZLF1 protein interacts physically and functionally with the histone acetylase CREBbinding protein
    • Adamson AL, Kenney S. 1999. The Epstein-Barr virus BZLF1 protein interacts physically and functionally with the histone acetylase CREBbinding protein. J. Virol. 73:6551-6558.
    • (1999) J. Virol. , vol.73 , pp. 6551-6558
    • Adamson, A.L.1    Kenney, S.2
  • 62
    • 0033049563 scopus 로고    scopus 로고
    • The amino-terminal C/H1 domain of CREB binding protein mediates zta transcriptional activation of latent Epstein-Barr virus
    • Zerby D, Chen CJ, Poon E, Lee D, Shiekhattar R, Lieberman PM. 1999. The amino-terminal C/H1 domain of CREB binding protein mediates zta transcriptional activation of latent Epstein-Barr virus. Mol. Cell. Biol. 19: 1617-1626.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1617-1626
    • Zerby, D.1    Chen, C.J.2    Poon, E.3    Lee, D.4    Shiekhattar, R.5    Lieberman, P.M.6
  • 63
    • 84866899397 scopus 로고    scopus 로고
    • BZLF1 governs CpG-methylated chromatin of Epstein-Barr virus reversing epigenetic repression
    • doi:10.1371/journal.ppat.1002902
    • Woellmer A, Arteaga-Salas JM, Hammerschmidt W. 2012. BZLF1 governs CpG-methylated chromatin of Epstein-Barr virus reversing epigenetic repression. PLoS Pathog. 8:e1002902. doi:10.1371/journal.ppat.1002902.
    • (2012) PLoS Pathog. , vol.8
    • Woellmer, A.1    Arteaga-salas, J.M.2    Hammerschmidt, W.3
  • 64
    • 70350327345 scopus 로고    scopus 로고
    • General and target-specific RNA binding properties of Epstein-Barr virus SM posttranscriptional regulatory protein
    • Han Z, Verma D, Hilscher C, Dittmer DP, Swaminathan S. 2009. General and target-specific RNA binding properties of Epstein-Barr virus SM posttranscriptional regulatory protein. J. Virol. 83:11635-11644.
    • (2009) J. Virol. , vol.83 , pp. 11635-11644
    • Han, Z.1    Verma, D.2    Hilscher, C.3    Dittmer, D.P.4    Swaminathan, S.5
  • 65
    • 0034979001 scopus 로고    scopus 로고
    • Epstein-Barr virus SM protein interacts withmRNAin vivo and mediates a gene-specific increase in cytoplasmic mRNA
    • Ruvolo V, Gupta AK, Swaminathan S. 2001. Epstein-Barr virus SM protein interacts withmRNAin vivo and mediates a gene-specific increase in cytoplasmic mRNA. J. Virol. 75:6033-6041.
    • (2001) J. Virol. , vol.75 , pp. 6033-6041
    • Ruvolo, V.1    Gupta, A.K.2    Swaminathan, S.3
  • 66
    • 0032555233 scopus 로고    scopus 로고
    • The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression
    • Ruvolo V, Wang E, Boyle S, Swaminathan S. 1998. The Epstein-Barr virus nuclear protein SM is both a post-transcriptional inhibitor and activator of gene expression. Proc. Natl. Acad. Sci. U. S. A. 95:8852-8857.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 8852-8857
    • Ruvolo, V.1    Wang, E.2    Boyle, S.3    Swaminathan, S.4
  • 67
    • 0027265976 scopus 로고
    • Epstein-Barr virus gene expression in oral hairy leukoplakia
    • Lau R, Middeldorp J, Farrell PJ. 1993. Epstein-Barr virus gene expression in oral hairy leukoplakia. Virology 195:463-474.
    • (1993) Virology , vol.195 , pp. 463-474
    • Lau, R.1    Middeldorp, J.2    Farrell, P.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.