-
1
-
-
33645017891
-
EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5
-
Bark-Jones SJ, Webb HM, West MJ. 2006. EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5. Oncogene 25:1775-1785.
-
(2006)
Oncogene
, vol.25
, pp. 1775-1785
-
-
Bark-Jones, S.J.1
Webb, H.M.2
West, M.J.3
-
2
-
-
78149302949
-
CpG-methylation regulates a class of Epstein-Barr virus promoters
-
Bergbauer M, et al. 2010. CpG-methylation regulates a class of Epstein-Barr virus promoters. PLoS Pathog. 6:e1001114.
-
(2010)
PLoS Pathog
, vol.6
-
-
Bergbauer, M.1
-
3
-
-
19944397140
-
BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186
-
Bhende PM, Seaman WT, Delecluse HJ, Kenney SC. 2005. BZLF1 activation of the methylated form of the BRLF1 immediate-early promoter is regulated by BZLF1 residue 186. J. Virol. 79:7338-7348.
-
(2005)
J. Virol.
, vol.79
, pp. 7338-7348
-
-
Bhende, P.M.1
Seaman, W.T.2
Delecluse, H.J.3
Kenney, S.C.4
-
4
-
-
6944244957
-
The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome
-
Bhende PM, Seaman WT, Delecluse HJ, Kenney SC. 2004. The EBV lytic switch protein, Z, preferentially binds to and activates the methylated viral genome. Nat. Genet. 36:1099-1104.
-
(2004)
Nat. Genet.
, vol.36
, pp. 1099-1104
-
-
Bhende, P.M.1
Seaman, W.T.2
Delecluse, H.J.3
Kenney, S.C.4
-
5
-
-
0036786424
-
Signal transduction and transcription factor modification during reactivation of Epstein-Barr virus from latency
-
Bryant H, Farrell PJ. 2002. Signal transduction and transcription factor modification during reactivation of Epstein-Barr virus from latency. J. Virol. 76:10290-10298.
-
(2002)
J. Virol.
, vol.76
, pp. 10290-10298
-
-
Bryant, H.1
Farrell, P.J.2
-
6
-
-
0034667777
-
Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation
-
Chang LK, Liu ST. 2000. Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation. Nucleic Acids Res. 28: 3918-3925.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 3918-3925
-
-
Chang, L.K.1
Liu, S.T.2
-
7
-
-
43249126604
-
Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virusinfected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors
-
Countryman JK, Gradoville L, Miller G. 2008. Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virusinfected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors. J. Virol. 82:4706-4719.
-
(2008)
J. Virol.
, vol.82
, pp. 4706-4719
-
-
Countryman, J.K.1
Gradoville, L.2
Miller, G.3
-
8
-
-
79956067296
-
Valproic acid antagonizes the capacity of other histone deacetylase inhibitors to activate the Epstein-Barr virus lytic cycle
-
Daigle D, et al. 2011. Valproic acid antagonizes the capacity of other histone deacetylase inhibitors to activate the Epstein-Barr virus lytic cycle. J. Virol. 85:5628-5643.
-
(2011)
J. Virol.
, vol.85
, pp. 5628-5643
-
-
Daigle, D.1
-
9
-
-
63449134294
-
Methylation-dependent binding of the Epstein-Barr virus BZLF1 protein to viral promoters
-
Dickerson SJ, et al. 2009. Methylation-dependent binding of the Epstein-Barr virus BZLF1 protein to viral promoters. PLoS Pathog. 5:e1000356.
-
(2009)
PLoS Pathog
, vol.5
-
-
Dickerson, S.J.1
-
10
-
-
77957922753
-
A subset of replication proteins enhances origin recognition and lytic replication by the Epstein-Barr virus ZEBRA protein
-
El-Guindy A, Heston L, Miller G. 2010. A subset of replication proteins enhances origin recognition and lytic replication by the Epstein-Barr virus ZEBRA protein. PLoS Pathog. 6:e1001054.
-
(2010)
PLoS Pathog
, vol.6
-
-
El-Guindy, A.1
Heston, L.2
Miller, G.3
-
11
-
-
77952677694
-
Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner
-
Ellis AL, Wang Z, Yu X, Mertz JE. 2010. Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner. J. Virol. 84:6139-6152.
-
(2010)
J. Virol.
, vol.84
, pp. 6139-6152
-
-
Ellis, A.L.1
Wang, Z.2
Yu, X.3
Mertz, J.E.4
-
12
-
-
34248184571
-
H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation
-
Ewald B, Sampath D, Plunkett W. 2007. H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation. Mol. Cancer Ther. 6:1239-1248.
-
(2007)
Mol. Cancer Ther.
, vol.6
, pp. 1239-1248
-
-
Ewald, B.1
Sampath, D.2
Plunkett, W.3
-
13
-
-
0034660443
-
The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators
-
Feederle R, et al. 2000. The Epstein-Barr virus lytic program is controlled by the co-operative functions of two transactivators. EMBO J. 19: 3080-3089.
-
(2000)
EMBO J
, vol.19
, pp. 3080-3089
-
-
Feederle, R.1
-
14
-
-
61849085358
-
The dynamic DNA methylomes of doublestranded DNA viruses associated with human cancer
-
Fernandez AF, et al. 2009. The dynamic DNA methylomes of doublestranded DNA viruses associated with human cancer. Genome Res. 19: 438-451.
-
(2009)
Genome Res
, vol.19
, pp. 438-451
-
-
Fernandez, A.F.1
-
15
-
-
0028915139
-
Replication of Epstein-Barr virus oriLyt: lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays
-
Fixman ED, Hayward GS, Hayward SD. 1995. Replication of Epstein-Barr virus oriLyt: lack of a dedicated virally encoded origin-binding protein and dependence on Zta in cotransfection assays. J. Virol. 69: 2998-3006.
-
(1995)
J. Virol.
, vol.69
, pp. 2998-3006
-
-
Fixman, E.D.1
Hayward, G.S.2
Hayward, S.D.3
-
16
-
-
0026708186
-
trans-acting requirements for replication of Epstein-Barr virus ori-Lyt
-
Fixman ED, Hayward GS, Hayward SD. 1992. trans-acting requirements for replication of Epstein-Barr virus ori-Lyt. J. Virol. 66:5030-5039.
-
(1992)
J. Virol.
, vol.66
, pp. 5030-5039
-
-
Fixman, E.D.1
Hayward, G.S.2
Hayward, S.D.3
-
17
-
-
0025214570
-
Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1
-
Flemington E, Speck SH. 1990. Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1. J. Virol. 64:1227-1232.
-
(1990)
J. Virol.
, vol.64
, pp. 1227-1232
-
-
Flemington, E.1
Speck, S.H.2
-
18
-
-
0025719722
-
Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis
-
Flemington EK, Goldfeld AE, Speck SH. 1991. Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis. J. Virol. 65:7073-7077.
-
(1991)
J. Virol.
, vol.65
, pp. 7073-7077
-
-
Flemington, E.K.1
Goldfeld, A.E.2
Speck, S.H.3
-
20
-
-
0032785445
-
Detection of Epstein-Barr virus (EBV) genomes in the serum of patients with EBV-associated Hodgkin's disease
-
Gallagher A, et al. 1999. Detection of Epstein-Barr virus (EBV) genomes in the serum of patients with EBV-associated Hodgkin's disease. Int. J. Cancer 84:442-448.
-
(1999)
Int. J. Cancer 84
, pp. 442-448
-
-
Gallagher, A.1
-
21
-
-
16544365033
-
Quantitative sequential chromatin immunoprecipitation, a method for analyzing co-occupancy of proteins at genomic regions in vivo
-
Geisberg JV, Struhl K. 2004. Quantitative sequential chromatin immunoprecipitation, a method for analyzing co-occupancy of proteins at genomic regions in vivo. Nucleic Acids Res. 32:e151.
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Geisberg, J.V.1
Struhl, K.2
-
22
-
-
0036193460
-
MEF2-mediated recruitment of class II HDAC at the EBV immediate-early gene BZLF1 links latency and chromatin remodeling
-
Gruffat H, Manet E, Sergeant A. 2002. MEF2-mediated recruitment of class II HDAC at the EBV immediate-early gene BZLF1 links latency and chromatin remodeling. EMBO Rep. 3:141-146.
-
(2002)
EMBO Rep
, vol.3
, pp. 141-146
-
-
Gruffat, H.1
Manet, E.2
Sergeant, A.3
-
23
-
-
77951209628
-
Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death
-
Hui KF, Chiang AK. 2010. Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death. Int. J. Cancer 126:2479-2489.
-
(2010)
Int. J. Cancer
, vol.126
, pp. 2479-2489
-
-
Hui, K.F.1
Chiang, A.K.2
-
24
-
-
0033987840
-
Histone acetylation and reactivation of Epstein-Barr virus from latency
-
Jenkins PJ, Binne UK, Farrell PJ. 2000. Histone acetylation and reactivation of Epstein-Barr virus from latency. J. Virol. 74:710-720.
-
(2000)
J. Virol.
, vol.74
, pp. 710-720
-
-
Jenkins, P.J.1
Binne, U.K.2
Farrell, P.J.3
-
25
-
-
76249132533
-
AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome
-
Kalla M, Schmeinck A, Bergbauer M, Pich D, Hammerschmidt W. 2010. AP-1 homolog BZLF1 of Epstein-Barr virus has two essential functions dependent on the epigenetic state of the viral genome. Proc. Natl. Acad. Sci. U. S. A. 107:850-855.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 850-855
-
-
Kalla, M.1
Schmeinck, A.2
Bergbauer, M.3
Pich, D.4
Hammerschmidt, W.5
-
26
-
-
42949174160
-
Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein
-
Karlsson QH, Schelcher C, Verrall E, Petosa C, Sinclair AJ. 2008. Methylated DNA recognition during the reversal of epigenetic silencing is regulated by cysteine and serine residues in the Epstein-Barr virus lytic switch protein. PLoS Pathog. 4:e1000005.
-
(2008)
PLoS Pathog
, vol.4
-
-
Karlsson, Q.H.1
Schelcher, C.2
Verrall, E.3
Petosa, C.4
Sinclair, A.J.5
-
27
-
-
84929262107
-
Reactivation and lytic replication of EBV
-
Arvin A, et al (ed), Cambridge University Press, Cambridge, United Kingdom
-
Kenney SC. 2007. Reactivation and lytic replication of EBV, p 403-433. In Arvin A, et al (ed), Human herpesviruses: biology, therapy, and immunoprophylaxis. Cambridge University Press, Cambridge, United Kingdom.
-
(2007)
Human herpesviruses: biology, therapy, and immunoprophylaxis
, pp. 403-433
-
-
Kenney, S.C.1
-
28
-
-
0037213910
-
ZEB negatively regulates the lytic-switch BZLF1 gene promoter of Epstein-Barr virus
-
Kraus RJ, Perrigoue JG, Mertz JE. 2003. ZEB negatively regulates the lytic-switch BZLF1 gene promoter of Epstein-Barr virus. J. Virol. 77: 199-207.
-
(2003)
J. Virol.
, vol.77
, pp. 199-207
-
-
Kraus, R.J.1
Perrigoue, J.G.2
Mertz, J.E.3
-
29
-
-
14844336913
-
Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment
-
Kudoh A, et al. 2005. Epstein-Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment. J. Biol. Chem. 280:8156-8163.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 8156-8163
-
-
Kudoh, A.1
-
31
-
-
0024328960
-
The switch between EBV latency and replication
-
Miller G. 1989. The switch between EBV latency and replication. Yale J. Biol. Med. 62:205-213.
-
(1989)
Yale J. Biol. Med.
, vol.62
, pp. 205-213
-
-
Miller, G.1
-
32
-
-
79959364715
-
Involvement of Jun dimerization protein 2 (JDP2) in the maintenance of Epstein-Barr virus latency
-
Murata T, et al. 2011. Involvement of Jun dimerization protein 2 (JDP2) in the maintenance of Epstein-Barr virus latency. J. Biol. Chem. 286: 22007-22016.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22007-22016
-
-
Murata, T.1
-
33
-
-
0027257936
-
Strain variation in Epstein-Barr virus immediate-early genes
-
Packham G, Brimmell M, Cook D, Sinclair AJ, Farrell PJ. 1993. Strain variation in Epstein-Barr virus immediate-early genes. Virology 192: 541-550.
-
(1993)
Virology
, vol.192
, pp. 541-550
-
-
Packham, G.1
Brimmell, M.2
Cook, D.3
Sinclair, A.J.4
Farrell, P.J.5
-
34
-
-
80055084043
-
RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus
-
Palermo RD, Webb HM, West MJ. 2011. RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus. PLoS Pathog. 7:e1002334.
-
(2011)
PLoS Pathog
, vol.7
-
-
Palermo, R.D.1
Webb, H.M.2
West, M.J.3
-
35
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull TT, et al. 2000. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10:886-895.
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
-
36
-
-
0003401079
-
-
5th ed.Lippincott/Williams and Wilkins, Philadelphia, PA
-
Rickinson A, Kieff E (ed). 2007.Epstein-Barr virus, 5th ed.Lippincott/Williams and Wilkins, Philadelphia, PA.
-
(2007)
Epstein-Barr virus
-
-
Rickinson, A.1
Kieff, E.2
-
37
-
-
0034737439
-
Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139
-
Rogakou EP, Nieves-Neira W, Boon C, Pommier Y, Bonner WM. 2000. Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139. J. Biol. Chem. 275:9390-9395.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9390-9395
-
-
Rogakou, E.P.1
Nieves-Neira, W.2
Boon, C.3
Pommier, Y.4
Bonner, W.M.5
-
38
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. 1998. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273:5858-5868.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
39
-
-
70749143567
-
Burkitt's lymphoma: the Rosetta Stone deciphering Epstein-Barr virus biology
-
Rowe M, Kelly GL, Bell AI, Rickinson AB. 2009. Burkitt's lymphoma: the Rosetta Stone deciphering Epstein-Barr virus biology. Semin. Cancer Biol. 19:377-388.
-
(2009)
Semin. Cancer Biol.
, vol.19
, pp. 377-388
-
-
Rowe, M.1
Kelly, G.L.2
Bell, A.I.3
Rickinson, A.B.4
-
40
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
Rozen S, Skaletsky H. 2000. Primer3 on the WWW for general users and for biologist programmers. Methods Mol. Biol. 132:365-386.
-
(2000)
Methods Mol. Biol.
, vol.132
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.2
-
41
-
-
0043169617
-
bZIP proteins of human gammaherpesviruses
-
Sinclair AJ. 2003. bZIP proteins of human gammaherpesviruses. J. Gen. Virol. 84:1941-1949.
-
(2003)
J. Gen. Virol.
, vol.84
, pp. 1941-1949
-
-
Sinclair, A.J.1
-
42
-
-
0026163624
-
Pathways of activation of the Epstein-Barr virus productive cycle
-
Sinclair AJ, Brimmell M, Shanahan F, Farrell PJ. 1991. Pathways of activation of the Epstein-Barr virus productive cycle. J. Virol. 65: 2237-2244.
-
(1991)
J. Virol.
, vol.65
, pp. 2237-2244
-
-
Sinclair, A.J.1
Brimmell, M.2
Shanahan, F.3
Farrell, P.J.4
-
44
-
-
77956167119
-
Heterochromatin silencing of p53 target genes by a small viral protein
-
Soria C, Estermann FE, Espantman KC, O'Shea CC. 2010. Heterochromatin silencing of p53 target genes by a small viral protein. Nature 466: 1076-1081.
-
(2010)
Nature
, vol.466
, pp. 1076-1081
-
-
Soria, C.1
Estermann, F.E.2
Espantman, K.C.3
O'Shea, C.C.4
-
45
-
-
0030760456
-
Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene
-
Speck SH, Chatila T, Flemington E. 1997. Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene. Trends Microbiol. 5:399-405.
-
(1997)
Trends Microbiol
, vol.5
, pp. 399-405
-
-
Speck, S.H.1
Chatila, T.2
Flemington, E.3
-
46
-
-
0021351866
-
Cross-linking of surface immunoglobulins induces Epstein-Barr virus in Burkitt's lymphoma cell lines
-
Takada K. 1984. Cross-linking of surface immunoglobulins induces Epstein-Barr virus in Burkitt's lymphoma cell lines. Int. J. Cancer 33:27-32.
-
(1984)
Int. J. Cancer
, vol.33
, pp. 27-32
-
-
Takada, K.1
-
47
-
-
0024590981
-
Synchronous and sequential activation of latently infected Epstein-Barr virus genomes
-
Takada K, Ono Y. 1989. Synchronous and sequential activation of latently infected Epstein-Barr virus genomes. J. Virol. 63:445-449.
-
(1989)
J. Virol.
, vol.63
, pp. 445-449
-
-
Takada, K.1
Ono, Y.2
-
48
-
-
34249910944
-
Gammaherpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication
-
Tarakanova VL, et al. 2007. Gammaherpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host Microbe 1:275-286.
-
(2007)
Cell Host Microbe
, vol.1
, pp. 275-286
-
-
Tarakanova, V.L.1
-
50
-
-
34447338834
-
Hijacking the DNA damage response to enhance viral replication: gammaherpesvirus 68 orf36 phosphorylates histone H2AX
-
Xie A, Scully R. 2007. Hijacking the DNA damage response to enhance viral replication: gammaherpesvirus 68 orf36 phosphorylates histone H2AX. Mol. Cell 27:178-179.
-
(2007)
Mol. Cell
, vol.27
, pp. 178-179
-
-
Xie, A.1
Scully, R.2
-
51
-
-
34548147218
-
De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists
-
Ye J, Gradoville L, Daigle D, Miller G. 2007. De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists. J. Virol. 81:9279-9291.
-
(2007)
J. Virol.
, vol.81
, pp. 9279-9291
-
-
Ye, J.1
Gradoville, L.2
Daigle, D.3
Miller, G.4
-
52
-
-
4344643333
-
The Epstein-Barr virus transactivator Zta binds to its own promoter and is required for full promoter activity during anti-Ig and TGF-β1 mediated reactivation
-
Yin Q, Jupiter K, Flemington EK. 2004. The Epstein-Barr virus transactivator Zta binds to its own promoter and is required for full promoter activity during anti-Ig and TGF-β1 mediated reactivation. Virology 327: 134-143.
-
(2004)
Virology
, vol.327
, pp. 134-143
-
-
Yin, Q.1
Jupiter, K.2
Flemington, E.K.3
-
53
-
-
0026058670
-
Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia
-
Young LS, et al. 1991. Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia. J. Virol. 65:2868-2874.
-
(1991)
J. Virol.
, vol.65
, pp. 2868-2874
-
-
Young, L.S.1
|