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Volumn 25, Issue 1, 2013, Pages 59-65

Lessons from tumor reversion for cancer treatment

Author keywords

p53; Sertraline; Thioridazine; TPT1 TCTP; Tumor reversion

Indexed keywords

PHENOTHIAZINE DERIVATIVE; PRESENILIN 1; SEROTONIN UPTAKE INHIBITOR; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84871986116     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0b013e32835b7d21     Document Type: Review
Times cited : (60)

References (57)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011; 144:646-674
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 60749083173 scopus 로고    scopus 로고
    • The molecular programme of tumour reversion: The steps beyond malignant transformation
    • Telerman A, Amson R. The molecular programme of tumour reversion: The steps beyond malignant transformation. Nat Rev Cancer 2009; 9:206-216
    • (2009) Nat Rev Cancer , vol.9 , pp. 206-216
    • Telerman, A.1    Amson, R.2
  • 4
    • 9244251506 scopus 로고    scopus 로고
    • Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: Activation of the vertebrate homologue of the drosophila seven in absentia gene
    • Amson RB, Nemani M, Roperch JP, et al. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: Activation of the vertebrate homologue of the drosophila seven in absentia gene. Proc Natl Acad Sci USA 1996; 93:3953-3957
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3953-3957
    • Amson, R.B.1    Nemani, M.2    Roperch, J.P.3
  • 5
    • 9444262440 scopus 로고    scopus 로고
    • Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression
    • Nemani M, Linares-Cruz G, Bruzzoni-Giovanelli H, et al. Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression. Proc Natl Acad Sci USA 1996; 93:9039-9042
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 9039-9042
    • Nemani, M.1    Linares-Cruz, G.2    Bruzzoni-Giovanelli, H.3
  • 7
    • 0033529217 scopus 로고    scopus 로고
    • SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: Identification of common effectors with p53 and p21(Waf1
    • Roperch JP, Lethrone F, Prieur S, et al. SIAH-1 promotes apoptosis and tumor suppression through a network involving the regulation of protein folding, unfolding, and trafficking: Identification of common effectors with p53 and p21(Waf1). Proc Natl Acad Sci USA 1999; 96:8070-8073
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 8070-8073
    • Roperch, J.P.1    Lethrone, F.2    Prieur, S.3
  • 8
    • 0031593685 scopus 로고    scopus 로고
    • Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression
    • Roperch JP, Alvaro V, Prieur S, et al. Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression. Nat Med 1998; 4:835-838
    • (1998) Nat Med , vol.4 , pp. 835-838
    • Roperch, J.P.1    Alvaro, V.2    Prieur, S.3
  • 10
    • 47249118484 scopus 로고    scopus 로고
    • TCTP protects from apoptotic cell death by antagonizing bax function
    • Susini L, Besse S, Duflaut D, et al. TCTP protects from apoptotic cell death by antagonizing bax function. Cell Death Differ 2008; 15:1211-1220
    • (2008) Cell Death Differ , vol.15 , pp. 1211-1220
    • Susini, L.1    Besse, S.2    Duflaut, D.3
  • 11
    • 0037069412 scopus 로고    scopus 로고
    • Biological models and genes of tumor reversion: Cellular reprogramming through tpt1/TCTP and SIAH-1
    • Tuynder M, Susini L, Prieur S, et al. Biological models and genes of tumor reversion: Cellular reprogramming through tpt1/TCTP and SIAH-1. Proc Natl Acad Sci USA 2002; 99:14976-14981
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 14976-14981
    • Tuynder, M.1    Susini, L.2    Prieur, S.3
  • 12
    • 7444246058 scopus 로고    scopus 로고
    • Translationally controlled tumor protein is a target of tumor reversion
    • Tuynder M, Fiucci G, Prieur S, et al. Translationally controlled tumor protein is a target of tumor reversion. Proc Natl Acad Sci USA 2004; 101:15364- 15369
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15364-15369
    • Tuynder, M.1    Fiucci, G.2    Prieur, S.3
  • 13
    • 84855535930 scopus 로고    scopus 로고
    • Reciprocal repression between P53 and TCTP
    • Amson R, Pece S, Lespagnol A, et al. Reciprocal repression between P53 and TCTP. Nat Med 2012; 18:91-99
    • (2012) Nat Med , vol.18 , pp. 91-99
    • Amson, R.1    Pece, S.2    Lespagnol, A.3
  • 15
    • 33845867147 scopus 로고
    • The reversal of tumor growth
    • Braun AC. The reversal of tumor growth. Sci Am 1965; 213:75-83
    • (1965) Sci A.m. , vol.213 , pp. 75-83
    • Braun, A.C.1
  • 16
    • 0038224034 scopus 로고
    • A Demonstration Of The Recovery Of The crown-gall tumor cell with the use of complex tumors of single-cell origin
    • Braun AC. A demonstration of the recovery of the crown-gall tumor cell with the use of complex tumors of single-cell origin. Proc Natl Acad Sci USA 1959; 45:932-938
    • (1959) Proc Natl Acad Sci USA , vol.45 , pp. 932-938
    • Braun, A.C.1
  • 17
    • 37049230959 scopus 로고
    • Recovery of tumor cells from effects of the tumor-inducing principle in crown gall
    • Braun AC. Recovery of tumor cells from effects of the tumor-inducing principle in crown gall. Science 1951; 113:651-653
    • (1951) Science , vol.113 , pp. 651-653
    • Braun, A.C.1
  • 18
    • 84883845299 scopus 로고
    • Multipotentiality of single embryonal carcinoma cells
    • Kleinsmith LJ, Pierce GB Jr. Multipotentiality of single embryonal carcinoma cells. Cancer Res 1964; 24:1544-1551
    • (1964) Cancer Res , vol.24 , pp. 1544-1551
    • Kleinsmith, L.J.1    Pierce Jr., G.B.2
  • 19
    • 84965029816 scopus 로고
    • I. Demonstration of teratogenesis by metamorphosis of multipotential cells. Cancer
    • Pierce GB, Dixon FJ Jr. Testicular teratomas. I. Demonstration of teratogenesis by metamorphosis of multipotential cells. Cancer 1959; 12:573-583
    • (1959) Testicular teratomas , vol.12 , pp. 573-583
    • Pierce, G.B.1    Dixon Jr., F.J.2
  • 20
    • 0005922021 scopus 로고
    • Induction and differentiation of an epithelial tumour in the newt (Triturus cristatus)
    • Seilern-Aspang F, Kratochwil K. Induction and differentiation of an epithelial tumour in the newt (Triturus cristatus). J Embryol Exp Morphol 1962; 10:337- 356
    • (1962) J Embryol Exp Morphol , vol.10 , pp. 337-356
    • Seilern-Aspang, F.1    Kratochwil, K.2
  • 21
    • 0002572411 scopus 로고
    • Reversion in Hamster cells transformed by Rous sarcoma virus
    • Macpherson I. Reversion in Hamster cells transformed by Rous sarcoma virus. Science 1965; 148:1731-1733
    • (1965) Science , vol.148 , pp. 1731-1733
    • Macpherson, I.1
  • 22
    • 0014290104 scopus 로고
    • Growth control in cultured cells: Selection of sublines with increased sensitivity to contact inhibition and decreased tumorproducing ability
    • Pollack RE, Green H, Todaro GJ. Growth control in cultured cells: Selection of sublines with increased sensitivity to contact inhibition and decreased tumorproducing ability. Proc Natl Acad Sci USA 1968; 60:126-133
    • (1968) Proc Natl Acad Sci USA , vol.60 , pp. 126-133
    • Pollack, R.E.1    Green, H.2    Todaro, G.J.3
  • 23
    • 0014426049 scopus 로고
    • Reversion of properties in cells transformed by polyoma virus
    • Rabinowitz Z, Sachs L. Reversion of properties in cells transformed by polyoma virus. Nature 1968; 220:1203-1206
    • (1968) Nature , vol.220 , pp. 1203-1206
    • Rabinowitz, Z.1    Sachs, L.2
  • 24
    • 2342520813 scopus 로고
    • Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes
    • Noda M, Kitayama H, Matsuzaki T, et al. Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes. Proc Natl Acad Sci USA 1989; 86:162-166
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 162-166
    • Noda, M.1    Kitayama, H.2    Matsuzaki, T.3
  • 25
    • 0345366593 scopus 로고
    • Normal genetically mosaic mice produced from malignant teratocarcinoma cells
    • Mintz B, Illmensee K. Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc Natl Acad Sci USA 1975; 72:3585-3589
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 3585-3589
    • Mintz, B.1    Illmensee, K.2
  • 26
    • 12344318372 scopus 로고    scopus 로고
    • Context, tissue plasticity, and cancer: Are tumor stem cells also regulated by the microenvironment?
    • Bissell MJ, Labarge MA. Context, tissue plasticity, and cancer: Are tumor stem cells also regulated by the microenvironment? Cancer Cell 2005; 7:17- 23
    • (2005) Cancer Cell , vol.7 , pp. 17-23
    • Bissell, M.J.1    Labarge, M.A.2
  • 27
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver VM, Petersen OW, Wang F, et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol 1997; 137:231-245
    • (1997) J Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1    Petersen, O.W.2    Wang, F.3
  • 28
    • 33947583623 scopus 로고    scopus 로고
    • Reprogramming metastatic tumour cells with embryonic microenvironments
    • Hendrix MJ, Seftor EA, Seftor RE, et al. Reprogramming metastatic tumour cells with embryonic microenvironments. Nat Rev Cancer 2007; 7:246-255
    • (2007) Nat Rev Cancer , vol.7 , pp. 246-255
    • Hendrix, M.J.1    Seftor, E.A.2    Seftor, R.E.3
  • 29
    • 3042561857 scopus 로고    scopus 로고
    • Siah-1b is a direct transcriptional target of p53: Identification of the functional p53 responsive element in the siah-1b promoter
    • Fiucci G, Beaucourt S, Duflaut D, et al. Siah-1b is a direct transcriptional target of p53: Identification of the functional p53 responsive element in the siah-1b promoter. Proc Natl Acad Sci USA 2004; 101:3510-3515
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3510-3515
    • Fiucci, G.1    Beaucourt, S.2    Duflaut, D.3
  • 30
    • 0037418216 scopus 로고    scopus 로고
    • The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase
    • Passer BJ, Nancy-Portebois V, Amzallag N, et al. The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. Proc Natl Acad Sci USA 2003; 100:2284-2289
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2284-2289
    • Passer, B.J.1    Nancy-Portebois, V.2    Amzallag, N.3
  • 31
    • 8544232810 scopus 로고    scopus 로고
    • TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway
    • Amzallag N, Passer BJ, Allanic D, et al. TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway. J Biol Chem 2004; 279:46104-46112
    • (2004) J Biol Chem , vol.279 , pp. 46104-46112
    • Amzallag, N.1    Passer, B.J.2    Allanic, D.3
  • 32
    • 54049088501 scopus 로고    scopus 로고
    • Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice
    • Lespagnol A, Duflaut D, Beekman C, et al. Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ 2008; 15:1723- 1733
    • (2008) Cell Death Differ , vol.15 , pp. 1723-1733
    • Lespagnol, A.1    Duflaut, D.2    Beekman, C.3
  • 33
    • 10744220545 scopus 로고    scopus 로고
    • Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A
    • Cans C, Passer BJ, Shalak V, et al. Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A. Proc Natl Acad Sci USA 2003; 100:13892-13897
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 13892-13897
    • Cans, C.1    Passer, B.J.2    Shalak, V.3
  • 34
    • 16244384614 scopus 로고    scopus 로고
    • Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP
    • Liu H, Peng HW, Cheng YS, et al. Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP. Mol Cell Biol 2005; 25:3117-3126
    • (2005) Mol Cell Biol , vol.25 , pp. 3117-3126
    • Liu, H.1    Peng, H.W.2    Cheng, Y.S.3
  • 35
    • 23044467160 scopus 로고    scopus 로고
    • An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity
    • Yang Y, Yang F, Xiong Z, et al. An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity. Oncogene 2005; 24:4778-4788
    • (2005) Oncogene , vol.24 , pp. 4778-4788
    • Yang, Y.1    Yang, F.2    Xiong, Z.3
  • 36
    • 34347391544 scopus 로고    scopus 로고
    • A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner
    • Chen SH, Wu PS, Chou CH, et al. A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner. Mol Biol Cell 2007; 18:2525-2532
    • (2007) Mol Biol Cell , vol.18 , pp. 2525-2532
    • Chen, S.H.1    Wu, P.S.2    Chou, C.H.3
  • 37
    • 84865049831 scopus 로고    scopus 로고
    • Binding of translationally controlled tumour protein to the N-terminal domain of HDM2 is inhibited by Nutlin-3
    • Funston G, Goh W, Wei SJ, et al. Binding of translationally controlled tumour protein to the N-terminal domain of HDM2 is inhibited by Nutlin-3. PLoS One 2012; 7:e42642
    • (2012) PLoS One , vol.7
    • Funston, G.1    Goh, W.2    Wei, S.J.3
  • 38
    • 77951081382 scopus 로고    scopus 로고
    • The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling
    • Lin CJ, Robert F, Sukarieh R, et al. The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling. Cancer Res 2010; 70:3199-3208
    • (2010) Cancer Res , vol.70 , pp. 3199-3208
    • Lin, C.J.1    Robert, F.2    Sukarieh, R.3
  • 39
    • 33847174115 scopus 로고    scopus 로고
    • Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase
    • Hsu YC, Chern JJ, Cai Y, et al. Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase. Nature 2007; 445:785- 788
    • (2007) Nature , vol.445 , pp. 785-788
    • Hsu, Y.C.1    Chern, J.J.2    Cai, Y.3
  • 40
    • 84865126692 scopus 로고    scopus 로고
    • Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells
    • Kang S, Dong SM, Kim BR, et al. Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells. Apoptosis 2012; 17:989-997
    • (2012) Apoptosis , vol.17 , pp. 989-997
    • Kang, S.1    Dong, S.M.2    Kim, B.R.3
  • 41
    • 33646893689 scopus 로고    scopus 로고
    • Identifying off-target effects and hidden phenotypes of drugs in human cells
    • MacDonald ML, Lamerdin J, Owens S, et al. Identifying off-target effects and hidden phenotypes of drugs in human cells. Nat Chem Biol 2006; 2:329-337
    • (2006) Nat Chem Biol , vol.2 , pp. 329-337
    • MacDonald, M.L.1    Lamerdin, J.2    Owens, S.3
  • 42
    • 84861995326 scopus 로고    scopus 로고
    • Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells
    • Sachlos E, Risueno RM, Laronde S, et al. Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 2012; 149:1284-1297
    • (2012) Cell , vol.149 , pp. 1284-1297
    • Sachlos, E.1    Risueno, R.M.2    Laronde, S.3
  • 43
    • 33645776219 scopus 로고    scopus 로고
    • Use of antidepressants and risk of colorectal cancer: A nested case-control study
    • Xu W, Tamim H, Shapiro S, et al. Use of antidepressants and risk of colorectal cancer: A nested case-control study. Lancet Oncol 2006; 7:301-308
    • (2006) Lancet Oncol , vol.7 , pp. 301-308
    • Xu, W.1    Tamim, H.2    Shapiro, S.3
  • 45
    • 78349240636 scopus 로고    scopus 로고
    • Colorectal cancer risk in relation to antidepressant medication use
    • Chubak J, Boudreau DM, Rulyak SJ, Mandelson MT. Colorectal cancer risk in relation to antidepressant medication use. Int J Cancer 2011; 128:227-232
    • (2011) Int J Cancer , vol.128 , pp. 227-232
    • Chubak, J.1    Boudreau, D.M.2    Rulyak, S.J.3    Mandelson, M.T.4
  • 46
    • 84870580756 scopus 로고    scopus 로고
    • Targeting TCTP as a new therapeutic strategy in castration resistant prostate cancer
    • Epub ahead of print]
    • Baylot V, Katsogiannou M, Andrieu C, et al. Targeting TCTP as a new therapeutic strategy in castration resistant prostate cancer. Mol Ther 2012. [Epub ahead of print]
    • Mol Ther 2012. [
    • Baylot, V.1    Katsogiannou, M.2    Andrieu, C.3
  • 47
    • 84870394042 scopus 로고    scopus 로고
    • Chen SF. miR-27b-regulated TCTP as a novel plasma biomarker for oral cancer: From quantitative proteomics to posttranscriptional study
    • Epub ahead of print]
    • Lo WY, Wang HJ, Chiu CW, Chen SF. miR-27b-regulated TCTP as a novel plasma biomarker for oral cancer: From quantitative proteomics to posttranscriptional study. J Proteomics 2012. [Epub ahead of print]
    • J Proteomics 2012. [
    • Lo, W.Y.1    Wang, H.J.2    Chiu, C.W.3
  • 48
    • 20544460148 scopus 로고    scopus 로고
    • Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
    • Van Es JH, van Gijn ME, Riccio O, et al. Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 2005; 435:959-963
    • (2005) Nature , vol.435 , pp. 959-963
    • Van Es, J.H.1    Van Gijn, M.E.2    Riccio, O.3
  • 49
    • 84863786154 scopus 로고    scopus 로고
    • Preclinical analysis of the gamma-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia
    • Samon JB, Castillo-Martin M, Hadler M, et al. Preclinical analysis of the gamma-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia. Mol Cancer Ther 2012; 11:1565-1575
    • (2012) Mol Cancer Ther , vol.11 , pp. 1565-1575
    • Samon, J.B.1    Castillo-Martin, M.2    Hadler, M.3
  • 50
    • 80051640151 scopus 로고    scopus 로고
    • Notch1 inhibition targets the leukemiainitiating cells in a Tal1/Lmo2 mouse model of T-ALL
    • Tatarek J, Cullion K, Ashworth T, et al. Notch1 inhibition targets the leukemiainitiating cells in a Tal1/Lmo2 mouse model of T-ALL. Blood 2011; 118:1579-1590
    • (2011) Blood , vol.118 , pp. 1579-1590
    • Tatarek, J.1    Cullion, K.2    Ashworth, T.3
  • 51
    • 80053331448 scopus 로고    scopus 로고
    • The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma
    • Huynh C, Poliseno L, Segura MF, et al. The novel gamma secretase inhibitor RO4929097 reduces the tumor initiating potential of melanoma. PLoS One 2011; 6:e25264
    • (2011) PLoS One , vol.6
    • Huynh, C.1    Poliseno, L.2    Segura, M.F.3
  • 52
    • 34548572895 scopus 로고    scopus 로고
    • Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers
    • Konishi J, Kawaguchi KS, Vo H, et al. Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers. Cancer Res 2007; 67:8051-8057
    • (2007) Cancer Res , vol.67 , pp. 8051-8057
    • Konishi, J.1    Kawaguchi, K.S.2    Vo, H.3
  • 53
    • 84856721785 scopus 로고    scopus 로고
    • MRK003, a gamma-secretase inhibitor exhibits promising in vitro preclinical activity in multiple myeloma and non-Hodgkin's lymphoma
    • Ramakrishnan V, Ansell S, Haug J, et al. MRK003, a gamma-secretase inhibitor exhibits promising in vitro preclinical activity in multiple myeloma and non-Hodgkin's lymphoma. Leukemia 2012; 26:340-348
    • (2012) Leukemia , vol.26 , pp. 340-348
    • Ramakrishnan, V.1    Ansell, S.2    Haug, J.3
  • 54
    • 84860374357 scopus 로고    scopus 로고
    • Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma
    • Cook N, Frese KK, Bapiro TE, et al. Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma. J Exp Med 2012; 209:437-444
    • (2012) J Exp Med , vol.209 , pp. 437-444
    • Cook, N.1    Frese, K.K.2    Bapiro, T.E.3
  • 55
    • 80052494506 scopus 로고    scopus 로고
    • Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence
    • Pandya K, Meeke K, Clementz AG, et al. Targeting both Notch and ErbB-2 signalling pathways is required for prevention of ErbB-2-positive breast tumour recurrence. Br J Cancer 2011; 105:796-806
    • (2011) Br J Cancer , vol.105 , pp. 796-806
    • Pandya, K.1    Meeke, K.2    Clementz, A.G.3
  • 56
    • 13144256688 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase- 9 and inhibition of tumor invasion by the membraneanchored glycoprotein RECK
    • Takahashi C, Sheng Z, Horan TP, et al. Regulation of matrix metalloproteinase- 9 and inhibition of tumor invasion by the membraneanchored glycoprotein RECK. Proc Natl Acad Sci USA 1998; 95: 13221-13226
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13221-13226
    • Takahashi, C.1    Sheng, Z.2    Horan, T.P.3
  • 57
    • 80052055075 scopus 로고    scopus 로고
    • A novel screen using the Reck tumor suppressor gene promoter detects both conventional and metastasis-suppressing anticancer drugs
    • Murai R, Yoshida Y, Muraguchi T, et al. A novel screen using the Reck tumor suppressor gene promoter detects both conventional and metastasis-suppressing anticancer drugs. Oncotarget 2010; 1:252-264.
    • (2010) Oncotarget , vol.1 , pp. 252-264
    • Murai, R.1    Yoshida, Y.2    Muraguchi, T.3


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